All Relations between lap and dopaminergic

Publication Sentence Publish Date Extraction Date Species
Heba M Mansour, Ahmed F Mohamed, Mahmoud M Khattab, Aiman S El-Khati. Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor. Brain research. 2024-03-30. PMID:38554797. our findings indicate that lap effectively alleviated motor impairment, improved histopathological abnormalities, and restored dopaminergic neurons in the substantia nigra. 2024-03-30 2024-04-02 rat
Heba M Mansour, Ahmed F Mohamed, Mahmoud M Khattab, Aiman S El-Khati. Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease. European journal of pharmacology. 2023-06-29. PMID:37385578. in the current study, administration of 100 mg/kg lap in rotenone-treated rats for 21 days ameliorates motor impairment, debilitated histopathological alterations, and revived dopaminergic neurons by increasing tyrosine hydroxylase (th) expression in sn, along with increased dopamine level. 2023-06-29 2023-08-14 rat
Thomas W Elston, David K Bilke. Anterior Cingulate Cortex Modulation of the Ventral Tegmental Area in an Effort Task. Cell reports. vol 19. issue 11. 2018-04-16. PMID:28614710. rats with implants in the acc and ventral tegmental area (vta), a dopaminergic brain area implicated in motivation, were trained to run laps around a rectangular track for a fixed reward, where each lap varied in physical effort (a 30-cm climbable barrier). 2018-04-16 2023-08-13 rat