All Relations between ko and corpus callosum

Publication Sentence Publish Date Extraction Date Species
Tomonori Hoshino, Hajime Takase, Hidehiro Ishikawa, Gen Hamanaka, Shintaro Kimura, Norito Fukuda, Ji Hyun Park, Hiroki Nakajima, Hisashi Shirakawa, Akihiro Shindo, Kyu-Won Kim, Irwin H Gelman, Josephine Lok, Ken Ara. Transcriptomic Profiles of AKAP12 Deficiency in Mouse Corpus Callosum. Bioinformatics and biology insights. vol 18. 2024-09-30. PMID:39345723. in this study, we investigate the impact of akap12 deficiency by transcriptome analysis using rna-sequencing (rna-seq) on the corpus callosum of akap12 knockout (ko) mice. 2024-09-30 2024-10-02 mouse
Sukanya G Gakare, Jay M Bhatt, Kishore Kumar S Narasimhan, Shashank M Dravi. Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions. PloS one. vol 18. issue 11. 2023-11-24. PMID:37983226. in contrast, in cuprizone-induced demyelination, we observed reduced mbp staining in the corpus callosum of glud1 ko mice. 2023-11-24 2023-11-28 mouse
Kay Richards, Nikola Jancovski, Eric Hanssen, Alan Connelly, Steve Petro. Atypical myelinogenesis and reduced axon caliber in the Scn1a variant model of Dravet syndrome: An electron microscopy pilot study of the developing and mature mouse corpus callosum. Brain research. vol 1751. 2021-11-30. PMID:33069731. morphometric analyses of axons within the corpus callosum were completed at p16 and p50 in scn1a heterozygote ko male mice and their age-matched wild-type littermates. 2021-11-30 2023-08-13 mouse
Kay Richards, Nikola Jancovski, Eric Hanssen, Alan Connelly, Steve Petro. Atypical myelinogenesis and reduced axon caliber in the Scn1a variant model of Dravet syndrome: An electron microscopy pilot study of the developing and mature mouse corpus callosum. Brain research. vol 1751. 2021-11-30. PMID:33069731. the data has indicated, in the absence of behavioral seizures, factors that governed a shift toward small calibre axons at p16 have persisted in adult scn1a heterozygote ko corpus callosum. 2021-11-30 2023-08-13 mouse
Da Shi, Su Xu, Jiachen Zhuo, Mary C McKenna, Rao P Gullapall. White Matter Alterations in Fmr1 Knockout Mice during Early Postnatal Brain Development. Developmental neuroscience. vol 41. issue 5-6. 2021-04-29. PMID:32348987. differences in the developmental accumulation of white matter and myelin between fmr1 ko and wt mice were observed in the corpus callosum, external and internal capsules, cerebral peduncle, and fimbria. 2021-04-29 2023-08-13 mouse
Rensheng Wan, Veronica T Cheli, Diara A Santiago-González, Shaina L Rosenblum, Qiuchen Wan, Pablo M Pae. Impaired Postnatal Myelination in a Conditional Knockout Mouse for the Ferritin Heavy Chain in Oligodendroglial Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 40. 2021-01-15. PMID:32868463. furthermore, the corpus callosum of fth ko animals presented a significant decrease in the percentage of remyelinated axons and a substantial reduction in the average myelin thickness. 2021-01-15 2023-08-13 mouse
Brendan B McAllister, David K Wright, Ryan C Wortman, Sandy R Shultz, Richard H Dyc. Elimination of vesicular zinc alters the behavioural and neuroanatomical effects of social defeat stress in mice. Neurobiology of stress. vol 9. 2020-10-01. PMID:30450385. volumetric analysis revealed that znt3 ko mice have larger corpus callosum and parietal cortex volumes, and that corpus callosum volume was decreased by stress in znt3 ko, but not wild type, mice. 2020-10-01 2023-08-13 mouse
Stephan C Collins, Ana Uzquiano, Mohammed Selloum, Olivia Wendling, Marion Gaborit, Maria Osipenko, Marie-Christine Birling, Binnaz Yalcin, Fiona Franci. The neuroanatomy of Eml1 knockout mice, a model of subcortical heterotopia. Journal of anatomy. vol 235. issue 3. 2020-09-11. PMID:31173351. eml1 ko mice on the c57bl/6n genetic background also appear to present a wider phenotype than the original mouse mutant, showing additional brain anomalies, such as corpus callosum abnormalities. 2020-09-11 2023-08-13 mouse
Frankie H F Lee, Terence K Y Lai, Ping Su, Fang Li. Altered cortical Cytoarchitecture in the Fmr1 knockout mouse. Molecular brain. vol 12. issue 1. 2020-05-26. PMID:31200759. in terms of glial cells, fmr1 ko mice exhibited an increase in olig2-oligodendrocytes, which corresponded to the abnormally higher myelin expression in the corpus callosum. 2020-05-26 2023-08-13 mouse
Phan H Truong, Giuseppe D Ciccotosto, Tobias D Merson, Loredana Spoerri, Mun Joo Chuei, Margaret Ayers, Yao Lulu Xing, Ben Emery, Roberto Cappa. Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons. Glia. vol 67. issue 3. 2019-06-13. PMID:30506868. in the peripheral nervous system, we identified that adult, but not juvenile ko mice, have lower densities of myelinated axons in their sciatic nerves while in the central nervous system, axons within both the optic nerves and corpus callosum of both ko mice were significantly hypomyelinated compared to wild-type (wt) controls. 2019-06-13 2023-08-13 mouse
Raffaella De Pace, Miguel Skirzewski, Markus Damme, Rafael Mattera, Jeffrey Mercurio, Arianne M Foster, Loreto Cuitino, Michal Jarnik, Victoria Hoffmann, H Douglas Morris, Tae-Un Han, Grazia M S Mancini, Andrés Buonanno, Juan S Bonifacin. Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. PLoS genetics. vol 14. issue 4. 2018-06-19. PMID:29698489. in addition, ap-4 ε ko mice display a thin corpus callosum and axonal swellings in various areas of the brain and spinal cord. 2018-06-19 2023-08-13 mouse
Lucas J Sosa, James S Malter, Jie Hu, Florentyna Bustos Plonka, Mariana Oksdath, Alvaro F Nieto Guil, Santiago Quiroga, Karl H Pfenninge. Protein interacting with NIMA (never in mitosis A)-1 regulates axonal growth cone adhesion and spreading through myristoylated alanine-rich C kinase substrate isomerization. Journal of neurochemistry. vol 137. issue 5. 2017-06-05. PMID:26991250. the pin1 ko mice exhibited disturbed neuronal projections from the cerebral cortex and reduced white matter tracks such as the corpus callosum. 2017-06-05 2023-08-13 mouse
Marco Bortolato, Sean C Godar, Loai Alzghoul, Junlin Zhang, Ryan D Darling, Kimberly L Simpson, Valentina Bini, Kevin Chen, Cara L Wellman, Rick C S Lin, Jean C Shi. Monoamine oxidase A and A/B knockout mice display autistic-like features. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22850464. furthermore, both maoa and a/b ko mice displayed neuropathological alterations reminiscent of typical asd features, including reduced thickness of the corpus callosum, increased dendritic arborization of pyramidal neurons in the prefrontal cortex and disrupted microarchitecture of the cerebellum. 2013-12-27 2023-08-12 mouse