All Relations between ift88 and hippocampus
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Hyun Jin Jung, Mi Suk Lee, Seung Hee Choi, Youngshik Cho. Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer's disease. Acta neuropathologica communications. vol 11. issue 1. 2023-09-04. PMID:37667395. |
to further address the regulation of dns by primary cilia, we conducted knockdown of the ift88 gene in hippocampal neurons, which impaired ev-mediated secretion of a\xce\xb2 and promoted accumulation of axonal spheroids. |
2023-09-04 |
2023-09-07 |
mouse |
Nicolas F Berbari, Erik B Malarkey, S M Zaki R Yazdi, Andrew D McNair, Jordyn M Kippe, Mandy J Croyle, Timothy W Kraft, Bradley K Yode. Hippocampal and cortical primary cilia are required for aversive memory in mice. PloS one. vol 9. issue 9. 2015-05-14. PMID:25184295. |
furthermore, hippocampal neurons from mutants displayed an altered paired-pulse response, suggesting that loss of ift88 can alter synaptic properties. |
2015-05-14 |
2023-08-13 |
mouse |
Nicolas F Berbari, Erik B Malarkey, S M Zaki R Yazdi, Andrew D McNair, Jordyn M Kippe, Mandy J Croyle, Timothy W Kraft, Bradley K Yode. Hippocampal and cortical primary cilia are required for aversive memory in mice. PloS one. vol 9. issue 9. 2015-05-14. PMID:25184295. |
to determine if neuronal cilia have a role in behavior we specifically disrupted ciliogenesis in the cortex and hippocampus of mice through conditional deletion of the intraflagellar transport 88 (ift88) gene. |
2015-05-14 |
2023-08-13 |
mouse |