| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guillermo Vázquez-Cabrera, Martin Škandík, Noémie Roncier, Farah Real Oualit, Mireia Cruz De Los Santos, Austeja Baleviciute, Mathilde Cheray, Bertrand Josep. ID2-ETS2 axis regulates the transcriptional acquisition of pro-tumoral microglia phenotype in glioma. Cell death & disease. vol 15. issue 7. 2024-07-17. PMID:39019900. |
id2 and ets2 genes were found to be expressed by the tumour-associated microglia isolated from human glioblastoma tumour biopsies. |
2024-07-17 |
2024-07-20 |
human |
| Guillermo Vázquez-Cabrera, Martin Škandík, Noémie Roncier, Farah Real Oualit, Mireia Cruz De Los Santos, Austeja Baleviciute, Mathilde Cheray, Bertrand Josep. ID2-ETS2 axis regulates the transcriptional acquisition of pro-tumoral microglia phenotype in glioma. Cell death & disease. vol 15. issue 7. 2024-07-17. PMID:39019900. |
collectively, our findings indicate that the regulation of ets2 by id2 plays a role in the transcriptional regulation of microglia in response to stimuli originating from glioblastoma cells, information that could lead to developing therapeutic strategies to manipulate microglial tumour-trophic functions. |
2024-07-17 |
2024-07-20 |
human |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
interestingly, in lipopolysaccharides (lps)-treated microglia, id2 increased and underwent a cytoplasmic relocation. |
2024-06-08 |
2024-06-11 |
Not clear |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
here, we identified that inhibitor of dna binding protein 2 (id2) was a negative regulator of tumor necrosis factor-α (tnfα) in cultured microglia. |
2024-06-08 |
2024-06-11 |
Not clear |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
collectively, our data delineate a novel effect of id2 on tnfα regulation in microglia, which may shed a light on the proinflammatory cytokines regulating in microglia associated neuroimmune disorders. |
2024-06-08 |
2024-06-11 |
Not clear |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
a novel effect of id2 in microglia tnfα regulation. |
2024-06-08 |
2024-06-11 |
Not clear |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
knockdown of id2 significantly increased the expression of tnfα in microglia, while overexpression of id2 inhibited tnfα expression. |
2024-06-08 |
2024-06-11 |
Not clear |
| Wenhui Wang, Asiru, Guoya Luo, Yanmei Chen, Yu Cui, Suning Ping, Yuan Che. A Novel Effect of Id2 in Microglia TNFα Regulation. Molecular neurobiology. 2024-06-08. PMID:38850351. |
immunoprecipitation and immunostaining results showed that by binding to the lim domain of id2, a scaffold protein pdz and lim 5 (pdlim5) involved in the id2 cytoplasmic relocation, which inactivated id2 and resulted in higher tnfα expression in lps-treated microglia. |
2024-06-08 |
2024-06-11 |
Not clear |
| Tetsuhiro Niidome, Satoru Matsuda, Hideki Nonaka, Akinori Akaike, Takeshi Kihara, Hachiro Sugimot. A molecular pathway involved in the generation of microtubule-associated protein 2-positive cells from microglia. Biochemical and biophysical research communications. vol 370. issue 1. 2008-05-12. PMID:18361915. |
immunocytochemical analyses demonstrated that the generation of map2-positive and gfap-positive cells from microglia was promoted by bone morphogenetic proteins (bmps) and was inhibited by noggin which is a bmp antagonist, smad4 sirna and id2 sirna. |
2008-05-12 |
2023-08-12 |
Not clear |
| S F Tzeng, M Kahn, S Liva, J De Velli. Tumor necrosis factor-alpha regulation of the Id gene family in astrocytes and microglia during CNS inflammatory injury. Glia. vol 26. issue 2. 1999-09-03. PMID:10384879. |
id2 and id3 mrna+ cells were identified as gfap+ and s100 alpha + astrocytes as well as ed1+ microglia. |
1999-09-03 |
2023-08-12 |
rat |