| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sylvana I S Rendeiro de Noronha, Lauro Angelo Gonçalves de Moraes, James E Hassell, Christopher E Stamper, Mathew R Arnold, Jared D Heinze, Christine L Foxx, Margaret M Lieb, Kristin E Cler, Bree L Karns, Sophia Jaekel, Kelsey M Loupy, Fernanda C S Silva, Deoclécio Alves Chianca-Jr, Christopher A Lowry, Rodrigo Cunha de Meneze. High-fat diet, microbiome-gut-brain axis signaling, and anxiety-like behavior in male rats. Biological research. vol 57. issue 1. 2024-05-05. PMID:38705984. |
we found that tph2, htr1a and slc6a4 mrna expression were increased in subregions of the dorsal raphe nucleus in the hfd, relative to control diet. |
2024-05-05 |
2024-05-08 |
rat |
| Sylvana I S Rendeiro de Noronha, Lauro Angelo Gonçalves de Moraes, James E Hassell, Christopher E Stamper, Mathew R Arnold, Jared D Heinze, Christine L Foxx, Margaret M Lieb, Kristin E Cler, Bree L Karns, Sophia Jaekel, Kelsey M Loupy, Fernanda C S Silva, Deoclécio Alves Chianca-Jr, Christopher A Lowry, Rodrigo Cunha de Meneze. High-fat diet, microbiome-gut-brain axis signaling, and anxiety-like behavior in male rats. Biological research. vol 57. issue 1. 2024-05-05. PMID:38705984. |
we show that hfd intake decreased alpha diversity and altered the community composition of the gut microbiome in association with obesity, increased brainstem tph2, htr1a and slc6a4 mrna expression, including in the caudal part of the dorsomedial dorsal raphe nucleus (cdrd), a subregion previously associated with stress- and anxiety-related behavioral responses, and, finally, increased anxiety-related defensive behavioral responses. |
2024-05-05 |
2024-05-08 |
rat |
| Steven C Wyler, Lauren J Donovan, Mia Yeager, Evan Deneri. Pet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin Neurons. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:25642596. |
in situ hybridizations revealed that virtually all 5-ht neurons in the dorsal raphe depend on pet-1 for slc22a3 expression; similar results were obtained for htr1a. |
2016-04-19 |
2023-08-13 |
Not clear |
| Gilda Baccini, Boris Mlinar, Enrica Audero, Cornelius Thilo Gross, Renato Corradett. Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors. PloS one. vol 7. issue 9. 2013-02-26. PMID:23028768. |
impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1a (htr1a) receptors. |
2013-02-26 |
2023-08-12 |
mouse |
| Younger W-Y Yu, Shih-Jen Tsai, Ying-Jay Liou, Chen-Jee Hong, Tai-Jui Che. Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 16. issue 7. 2006-11-14. PMID:16458487. |
the firing rate of dorsal raphe serotonergic neurons is modulated by somatodendritic 5-hydroxytryptamine 1a (htr1a) autoreceptors. |
2006-11-14 |
2023-08-12 |
Not clear |
| C-J Hong, T-J Chen, Y W-Y Yu, S-J Tsa. Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder. The pharmacogenomics journal. vol 6. issue 1. 2006-02-13. PMID:16302021. |
the firing rate of dorsal raphe serotonergic neurons is controlled by somatodendritic 5-hydroxytryptamine 1a (htr1a) autoreceptors, and desensitization of these receptors is implicated in the antidepressant mechanism of selective serotonin reuptake inhibitors. |
2006-02-13 |
2023-08-12 |
Not clear |