| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| José Luis Ferran, Luis Puelle. Atypical Course of the Habenulo-Interpeduncular Tract in Chick Embryos. The Journal of comparative neurology. vol 532. issue 7. 2024-07-04. PMID:38961604. |
it typically emerges out of the caudal hb, courses dorsoventrally across thalamic alar and basal plates just in front of the thalamo-pretectal boundary, and then sharply bends 90° caudalwards at paramedian basal plate levels (this is the "retroflexion"), to approach longitudinally via paramedian pretectum and midbrain the rostralmost hindbrain, specifically the prepontine median interpeduncular complex across isthmus and rhombomere 1. |
2024-07-04 |
2024-07-10 |
chicken |
| Nora L Salaberry, Jorge Mendoz. The circadian clock in the mouse habenula is set by catecholamines. Cell and tissue research. 2021-11-24. PMID:34816282. |
anatomically, the hb projects to the midbrain dopamine (da) and serotonin (5-ht) systems, and it receives inputs from the forebrain, midbrain, and brainstem. |
2021-11-24 |
2023-08-13 |
mouse |
| Seo-Eun Cho, Chan-A Park, Kyoung-Sae Na, ChiHye Chung, Hyo-Jin Ma, Chang-Ki Kang, Seung-Gul Kan. Left-right asymmetric and smaller right habenula volume in major depressive disorder on high-resolution 7-T magnetic resonance imaging. PloS one. vol 16. issue 8. 2021-11-23. PMID:34343199. |
the habenula (hb) has been hypothesized to play an essential role in major depressive disorder (mdd) as it is considered to be an important node between fronto-limbic areas and midbrain monoaminergic structures based on animal studies. |
2021-11-23 |
2023-08-13 |
human |
| Bodhisattwa Banerjee, Debaprasad Koner, David Karasik, Nirmalendu Sah. Genome-wide identification of novel long non-coding RNAs and their possible roles in hypoxic zebrafish brain. Genomics. vol 113. issue 1 Pt 1. 2021-09-14. PMID:33264657. |
from the rna-seq in the forebrain (fb), midbrain (mb), and hindbrain (hb) regions of hypoxic and normoxic zebrafish, we identified novel lncrnas, whose potential cis targets showed involvement in neuronal development and differentiation pathways. |
2021-09-14 |
2023-08-13 |
zebrafish |
| Martin Metzger, Rudieri Souza, Leandro B Lima, Debora Bueno, Luciano Gonçalves, Chemutai Sego, Jose Donato, Sara J Shammah-Lagnad. Habenular connections with the dopaminergic and serotonergic system and their role in stress-related psychiatric disorders. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31833616. |
so far, research on hb has focused on the role of the lhb in regulating midbrain dopamine release. |
2021-06-28 |
2023-08-13 |
Not clear |
| Peng Qu, Yachun Wang, Lei Liu, Mengmeng Qi, Yimeng Sun, Siyang Zheng, Zichen Xu, Changhong Liu, Xiaoyan Bai, Qinggao Zhang, Limin Yan. Habenula lesions improve glucose metabolism in rats with type 2 diabetes by increasing insulin sensitivity and inhibiting gluconeogenesis. BMJ open diabetes research & care. vol 8. issue 1. 2021-06-21. PMID:32393480. |
the habenular nucleus (hb), a famous relay station in the midbrain, is vital for controlling many physiological functions of vertebrates. |
2021-06-21 |
2023-08-13 |
rat |
| Li Wang, Zhijian Zhang, Jiacheng Chen, Anne Manyande, Rafi Haddad, Qing Liu, Fuqiang X. Cell-Type-Specific Whole-Brain Direct Inputs to the Anterior and Posterior Piriform Cortex. Frontiers in neural circuits. vol 14. 2021-06-10. PMID:32116571. |
we found that for both types of neurons, apc and ppc share some similarities in input networks, with dominant inputs originating from the olfactory region (olf), followed by the cortical subplate (ctxsp), isocortex, cerebral nuclei (cnu), hippocampal formation (hpf) and interbrain (ib), whereas the midbrain (mb) and hindbrain (hb) were rarely labeled. |
2021-06-10 |
2023-08-13 |
Not clear |
| Edra London, Jason C Wester, Michelle Bloyd, Shelby Bettencourt, Chris J McBain, Constantine A Strataki. Loss of habenular Prkar2a reduces hedonic eating and increases exercise motivation. JCI insight. vol 5. issue 23. 2021-05-24. PMID:33141766. |
the habenula (hb) is a bilateral, evolutionarily conserved epithalamic structure connecting forebrain and midbrain structures that has gained attention for its roles in depression, addiction, rewards processing, and motivation. |
2021-05-24 |
2023-08-13 |
mouse |
| Esther Yang, Jin Yong Kim, Soo Hyun Yang, Eunsoo Lee, Woong Sun, Hyun Woo Lee, Hyun Ki. Three-Dimensional Analysis of Mouse Habenula Subnuclei Reveals Reduced Volume and Gene Expression in the Lipopolysaccharide-mediated Depression Model. Experimental neurobiology. vol 28. issue 6. 2020-09-28. PMID:31902158. |
the habenula (hb) is small but important brain structure, anatomically and functionally links the forebrain with the midbrain to modulate various neuropsychiatric functions associated with drug addiction and emotion-associated dysfunctions. |
2020-09-28 |
2023-08-13 |
mouse |
| Savannah N Gosnell, Kaylah N Curtis, Kenia Velasquez, J Christopher Fowler, Alok Madan, Wayne Goodman, Ramiro Sala. Habenular connectivity may predict treatment response in depressed psychiatric inpatients. Journal of affective disorders. vol 242. 2019-02-12. PMID:30195174. |
the habenula (hb) is a small midbrain structure that signals negative events and may play a major role in the etiology of psychiatric disorders including depression. |
2019-02-12 |
2023-08-13 |
Not clear |
| Albert Batalla, Judith R Homberg, Tatiana V Lipina, Guillaume Sescousse, Maartje Luijten, Svetlana A Ivanova, Arnt F A Schellekens, Anton J M Loone. The role of the habenula in the transition from reward to misery in substance use and mood disorders. Neuroscience and biobehavioral reviews. vol 80. 2018-07-10. PMID:28576510. |
the hb receives inputs from the septum, basal ganglia, hypothalamus, anterior cingulate and medial prefrontal cortex, and projects to several midbrain centers, most importantly the inhibitory rostromedial tegmental nucleus (rmtg) and the excitatory interpeduncular nucleus (ipn), which regulate the activity of midbrain monoaminergic nuclei. |
2018-07-10 |
2023-08-13 |
human |
| Laura-Joy Boulos, Emmanuel Darcq, Brigitte Lina Kieffe. Translating the Habenula-From Rodents to Humans. Biological psychiatry. vol 81. issue 4. 2017-08-10. PMID:27527822. |
the habenula (hb) is a central structure connecting forebrain to midbrain regions. |
2017-08-10 |
2023-08-13 |
human |
| M Carceller-Sindreu, J de Diego-Adeliño, M Serra-Blasco, Y Vives-Gilabert, A Martín-Blanco, D Puigdemont, E Álvarez, V Pérez, M J Portell. Volumetric MRI study of the habenula in first episode, recurrent and chronic major depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26404405. |
the habenula (hb) can play an important role in major depressive disorder (mdd) as it is a key node between fronto-limbic areas and midbrain monoaminergic structures. |
2016-08-26 |
2023-08-13 |
human |
| Z Leibovitz, C Shkolnik, K Krajden Haratz, G Malinger, I Shapiro, T Lerman-Sagi. Assessment of fetal midbrain and hindbrain in mid-sagittal cranial plane by three-dimensional multiplanar sonography. Part 1: comparison of new and established nomograms. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. vol 44. issue 5. 2015-06-29. PMID:24448830. |
to construct nomograms for fetal midbrain (mb) and hindbrain (hb) dimensions, assessed in the mid-sagittal cranial plane by three-dimensional multiplanar sonographic reconstruction (3d-mpr). |
2015-06-29 |
2023-08-12 |
Not clear |
| Z Leibovitz, C Shkolnik, K Krajden Haratz, G Malinger, I Shapiro, T Lerman-Sagi. Assessment of fetal midbrain and hindbrain in mid-sagittal cranial plane by three-dimensional multiplanar sonography. Part 2: application of nomograms to fetuses with posterior fossa malformations. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. vol 44. issue 5. 2015-06-29. PMID:24478245. |
to apply fetal midbrain (mb) and hindbrain (hb) nomograms, developed using three-dimensional multiplanar sonographic reconstruction (3d-mpr) in the mid-sagittal cranial plane, to fetuses with known posterior fossa malformations. |
2015-06-29 |
2023-08-12 |
Not clear |
| A James Barkovic. Developmental disorders of the midbrain and hindbrain. Frontiers in neuroanatomy. vol 6. 2012-10-02. PMID:22408608. |
malformations of the midbrain (mb) and hindbrain (hb) have become topics of considerable interest in the neurology and neuroscience literature in recent years. |
2012-10-02 |
2023-08-12 |
Not clear |
| Aldo Villalón, Mauricio Sepúlveda, Néstor Guerrero, Margarita M Meynard, Karina Palma, Miguel L Conch. Evolutionary plasticity of habenular asymmetry with a conserved efferent connectivity pattern. PloS one. vol 7. issue 4. 2012-08-30. PMID:22514727. |
the vertebrate habenulae (hb) is an evolutionary conserved dorsal diencephalic nuclear complex that relays information from limbic and striatal forebrain regions to the ventral midbrain. |
2012-08-30 |
2023-08-12 |
Not clear |
| Aldo Villalón, Mauricio Sepúlveda, Néstor Guerrero, Margarita M Meynard, Karina Palma, Miguel L Conch. Evolutionary plasticity of habenular asymmetry with a conserved efferent connectivity pattern. PloS one. vol 7. issue 4. 2012-08-30. PMID:22514727. |
these results suggest that the circuit design involving the hb of teleosts promotes structural flexibility depending on developmental, cognitive and/or behavioural pressures, without affecting the main midbrain connectivity output, thus unveiling a key conserved role of this connectivity trait in the function of the circuit. |
2012-08-30 |
2023-08-12 |
Not clear |
| Mark Zervas, Sandra Blaess, Alexandra L Joyne. Classical embryological studies and modern genetic analysis of midbrain and cerebellum development. Current topics in developmental biology. vol 69. 2009-09-22. PMID:16243598. |
the regions considered in this chapter are the mb and most-anterior hb (mb/ahb), which are derived from the mesencephalon (mes) and rhombomere 1 (r1), respectively. |
2009-09-22 |
2023-08-12 |
mouse |
| Mark Zervas, Sandra Blaess, Alexandra L Joyne. Classical embryological studies and modern genetic analysis of midbrain and cerebellum development. Current topics in developmental biology. vol 69. 2009-09-22. PMID:16243598. |
the brain can be divided into three primary broad regions: the forebrain, midbrain (mb), and hindbrain (hb), each of which contain further subdivisions. |
2009-09-22 |
2023-08-12 |
mouse |