| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| José da Silva, Lariza Oliveira de Souza, Maria Paula Arakaki Severo, Sarah Luize Camargo Rodrigues, Patrícia Molz, Patrícia Schonhofen, Alice Laschuk Herlinger, Nadja Schröde. Effects of the AMPAR Antagonist, Perampanel, on Cognitive Function in Rats Exposed to Neonatal Iron Overload. Molecular neurobiology. 2024-05-02. PMID:38696064. |
recognition and aversive memory were evaluated, ampar subunit phosphorylation, as well as the relative expression of genes such as gria1, gria2, dlg4, and cac, which code proteins involved in ampar anchoring. |
2024-05-02 |
2024-05-04 |
rat |
| Lindsay M Achzet, Darrell A Jackso. Sex-Dependent Differences in the Ischemia/Reperfusion-Induced Expression of AMPA Receptors. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396906. |
there was a rapid decrease in gria1 (glua1) and gria2 (glua2) mrna levels in the male hippocampus following ischemic insult, but this was not observed in females. |
2024-02-24 |
2024-02-26 |
rat |
| Francesco Matrisciano, Valentina Locci, Erbo Dong, Ferdinando Nicoletti, Alessandro Guidotti, Dennis R Grayso. Altered Expression and in vivo Activity of mGlu5 variant a Receptors in the striatum of BTBR mice: Novel insights into the pathophysiology of adult idiopathic forms of autism spectrum disorders. Current neuropharmacology. 2022-02-10. PMID:35139800. |
striatal up-regulation of mglu5 receptors was associated with changes in the expression of genes encoding for proteins involved in excitatory and inhibitory neurotransmission and synaptic plasticity, including fmr1, dlg4 (psd-95), shank3 (all increased), brd4, bdnf-exon ix, mef2c, and arc (all increased), gria2, glun1, nr2a (all increased) and grm1 (mglu1), grm2 (mglu2), gria1 (glua1), and gad1 (gad-67) (all decreased). |
2022-02-10 |
2023-08-13 |
mouse |
| Junta Nakahara, Yasunori Masubuchi, Kazumi Takashima, Yasunori Takahashi, Ryo Ichikawa, Tomohiro Nakao, Mihoko Koyanagi, Robert R Maronpot, Toshinori Yoshida, Shim-Mo Hayashi, Makoto Shibutan. Continuous exposure to amorphous formula of curcumin from the developmental stage facilitates anti-anxiety-like behavior and fear-extinction learning in rats. Nutrition research (New York, N.Y.). vol 85. 2021-10-08. PMID:33460863. |
the constitutive gene expression levels of gria1, gria2, grin2d, slc17a6, and slc17a7 were altered in the hippocampal dentate gyrus and amygdala on pnd 77. |
2021-10-08 |
2023-08-13 |
rat |
| Vasiliy V Reshetnikov, Polina E Kisaretova, Nikita I Ershov, Anastasia S Shulyupova, Dmitry Yu Oshchepkov, Natalia V Klimova, Anna V Ivanchihina, Tatiana I Merkulova, Natalia P Bonda. Genes associated with cognitive performance in the Morris water maze: an RNA-seq study. Scientific reports. vol 10. issue 1. 2021-04-28. PMID:33328525. |
in high-mwm-performance mice, we also demonstrated significant upregulation of the "flip" splice variant of gria1 and gria2 transcripts encoding subunits of ampa receptor. |
2021-04-28 |
2023-08-13 |
mouse |
| Florian Freudenber. Quantitative analysis of Gria1, Gria2, Dlg1 and Dlg4 expression levels in hippocampus following forced swim stress in mice. Scientific reports. vol 9. issue 1. 2020-11-04. PMID:31575955. |
quantitative analysis of gria1, gria2, dlg1 and dlg4 expression levels in hippocampus following forced swim stress in mice. |
2020-11-04 |
2023-08-13 |
mouse |
| Betina Elfving, Heidi Kaastrup Müller, Ignasi Oliveras, Tina Becher Østerbøg, Cristobal Rio-Alamos, Ana Sanchez-Gonzalez, Adolf Tobeña, Alberto Fernandez-Teruel, Susana Azna. Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-28. PMID:31228641. |
we performed a comprehensive characterization of the rha-i/rla-i rats by real-time qpcr and western blotting for 5-ht1a, 5-ht2a, mglu2, dopamine 1 and dopamine 2 receptors (drd1 and drd2), ampa receptor subunits gria1, gria2 and nmda receptor subunits grin1, grin2a and grin2b, as well as pre- and post-synaptic components in pfc and hippocampus (hip). |
2020-08-28 |
2023-08-13 |
rat |
| Gaoyi Yao, Yang Yun, Nan San. Differential effects between one week and four weeks exposure to same mass of SO2 on synaptic plasticity in rat hippocampus. Environmental toxicology. vol 31. issue 7. 2017-03-06. PMID:25534910. |
the results showed that the mrna level of synaptic plasticity marker arc, glutamate receptors (gria1, gria2, grin1, grin2a, and grin2b) and the protein expression of memory related kinase p-camkпα were consistently inhibited by so2 both in 1 week and 4 weeks exposure cases; the protein expression of presynaptic marker synaptophysin, postsynaptic density protein 95 (psd-95), protein kinase a (pka), and protein kinase c (pkc) were increased in 1 week exposure case, and decreased in 4 weeks exposure case. |
2017-03-06 |
2023-08-13 |
rat |
| Cong Zhang, Sheng Li, Yahui Sun, Wei Dong, Fengyuan Piao, Yongjun Piao, Shuang Liu, Huai Guan, Shengbo Y. Arsenic downregulates gene expression at the postsynaptic density in mouse cerebellum, including genes responsible for long-term potentiation and depression. Toxicology letters. vol 228. issue 3. 2014-09-12. PMID:24831965. |
among these differentially expressed genes, significant decreases in the mrna expressions of camkii, gria1, gria2, grin1, itpr1, grm1 and plcβ4 related to the ltp and ltd were found at the psd of mouse cerebellum exposed to arsenic. |
2014-09-12 |
2023-08-13 |
mouse |
| Anusha Priya, Kaid Johar, Bindu Nair, Margaret T T Wong-Rile. Specificity protein 4 (Sp4) regulates the transcription of AMPA receptor subunit GluA2 (Gria2). Biochimica et biophysica acta. vol 1843. issue 6. 2014-06-03. PMID:24576410. |
by means of multiple approaches, including electrophoretic mobility shift and supershift assays, chromatin immunoprecipitation, promoter mutations, real-time quantitative pcr, and western blot analysis, we found that sp4, but not sp1 or sp3, regulates the gria2, but not gria1, 3, or 4, subunit gene of the ampa receptor in a concurrent and parallel manner with nrf-1. |
2014-06-03 |
2023-08-12 |
Not clear |
| Alberto Chiesa, Concetta Crisafulli, Stefano Porcelli, Changsu Han, Ashwin A Patkar, Soo-Jung Lee, Moon Ho Park, Tae-Youn Jun, Alessandro Serretti, Chi-Un Pa. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. European archives of psychiatry and clinical neuroscience. vol 262. issue 4. 2012-10-18. PMID:22057216. |
influence of gria1, gria2 and gria4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. |
2012-10-18 |
2023-08-12 |
Not clear |
| Alberto Chiesa, Concetta Crisafulli, Stefano Porcelli, Changsu Han, Ashwin A Patkar, Soo-Jung Lee, Moon Ho Park, Tae-Youn Jun, Alessandro Serretti, Chi-Un Pa. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. European archives of psychiatry and clinical neuroscience. vol 262. issue 4. 2012-10-18. PMID:22057216. |
the present study is aimed to exploring whether some single nucleotide polymorphisms (snps) within gria1, gria2 and gria4 could be associated with major depressive disorder (mdd) and whether they could predict clinical outcomes in korean in-patients, respectively, treated with antidepressants. |
2012-10-18 |
2023-08-12 |
Not clear |
| Cynthia L Bethea, Arubala P Redd. Ovarian steroids increase glutamatergic related gene expression in serotonin neurons of macaques. Molecular and cellular neurosciences. vol 49. issue 3. 2012-07-13. PMID:22154832. |
comparison of the relative expression or log relative expression in ovx-controls to combined e and e+p treated groups with t-tests showed a significant increase in ampa1 (gria1), ampa2 (gria2), ampa4 (gria4), nmda2a (grin2a), metabotrophic glutamate receptor (grm1), glutamine synthetase (glul), glutamate dehydrogenase (glud), glutamate cysteine ligase modifier subunit (gclm), the glutamate transporter 2 (slc1a2) and the glutamate transporter 3 (slc1a3) with steroid treatment. |
2012-07-13 |
2023-08-12 |
monkey |
| Alberto Chiesa, Concetta Crisafulli, Stefano Porcelli, Beatrice Balzarro, Changsu Han, Ashwin A Patkar, Soo-Jung Lee, Moon Ho Park, Chi-Un Pae, Alessandro Serrett. Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder. International journal of psychiatry in clinical practice. vol 16. issue 1. 2012-04-27. PMID:22122651. |
case-control association study of gria1, gria2 and gria4 polymorphisms in bipolar disorder. |
2012-04-27 |
2023-08-12 |
Not clear |
| Alberto Chiesa, Concetta Crisafulli, Stefano Porcelli, Beatrice Balzarro, Changsu Han, Ashwin A Patkar, Soo-Jung Lee, Moon Ho Park, Chi-Un Pae, Alessandro Serrett. Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder. International journal of psychiatry in clinical practice. vol 16. issue 1. 2012-04-27. PMID:22122651. |
the present study aimed to investigate whether some single nucleotide polymorphisms (snps) within gria1, gria2 and gria4 could be associated with bipolar disorder (bd) and they could predict clinical outcomes in in-patients with bd treated with mood stabilizers. |
2012-04-27 |
2023-08-12 |
Not clear |
| Concetta Crisafulli, Alberto Chiesa, Diana De Ronchi, Changsu Han, Soo-Jung Lee, Moon Ho Park, Ashwin A Patkar, Chi-Un Pae, Alessandro Serrett. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22094384. |
influence of gria1, gria2 and gria4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. |
2012-04-24 |
2023-08-12 |
Not clear |
| Concetta Crisafulli, Alberto Chiesa, Diana De Ronchi, Changsu Han, Soo-Jung Lee, Moon Ho Park, Ashwin A Patkar, Chi-Un Pae, Alessandro Serrett. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22094384. |
one hundred forty five patients with md, 221 in-patients with schizophrenia and 170 psychiatrically healthy controls were genotyped for 17 snps within gria1, gria2 and gria4. |
2012-04-24 |
2023-08-12 |
Not clear |
| Concetta Crisafulli, Alberto Chiesa, Diana De Ronchi, Changsu Han, Soo-Jung Lee, Moon Ho Park, Ashwin A Patkar, Chi-Un Pae, Alessandro Serrett. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22094384. |
our findings provide no evidence for an association between snps within gria1, gria2 and gria4 under investigation and schizophrenia susceptibility, although rs3813296 (gria2) could be associated with improvement on panss negative scores. |
2012-04-24 |
2023-08-12 |
Not clear |
| Concetta Crisafulli, Alberto Chiesa, Diana De Ronchi, Changsu Han, Soo-Jung Lee, Moon Ho Park, Ashwin A Patkar, Chi-Un Pae, Alessandro Serrett. Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22094384. |
the present study is aimed at exploring whether some single nucleotide polymorphisms (snps) within gria1, gria2 and gria4 could be associated with schizophrenia and whether they could predict clinical outcomes in korean in-patients treated with antipsychotics. |
2012-04-24 |
2023-08-12 |
Not clear |
| J A O'Connor, E C Muly, S E Arnold, S E Hemb. AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs. Schizophrenia research. vol 90. issue 1-3. 2007-05-30. PMID:17141476. |
however, in rhesus monkeys chronically treated with antipsychotic drugs, clozapine treatment significantly decreased gria1 and increased gria3 mrna expression, while both clozapine and haloperidol increased the expression of gria2 subunit mrna. |
2007-05-30 |
2023-08-12 |
human |