Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kiah A Spencer, Alexandra Boogers, Srdjan Sumarac, David B J Crompton, Leon A Steiner, Luka Zivkovic, Yijinmide Buren, Alexandre Boutet, Andres M Lozano, Suneil K Kalia, William D Hutchison, Alfonso Fasano, Luka Milosevi. Modulating inhibitory synaptic plasticity to restore basal ganglia dynamics in Parkinson's disease. Brain : a journal of neurology. 2025-03-12. PMID:40073201. |
parkinson's disease is characterized, in part, by hypoactivity of direct pathway inhibitory projections from striatum to the globus pallidus internus (gpi) and indirect pathway inhibitory projections from globus pallidus externus (gpe) to the subthalamic nucleus (stn). |
2025-03-12 |
2025-03-15 |
Not clear |
Tian Wei, Zhu Guanyu, Fan Shiying, Meng Fangang, Yang Anchao, Zhang Jiangu. STN and GPi-Deep Brain Stimulation for Primary Cervical Dystonia. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 35. issue 2. 2025-02-12. PMID:39936204. |
to evaluate the safety and efficiency of deep brain stimulation (dbs) in the treatment of primary cervical dystonia (cd) and to compare the difference between the stn (subthalamic nucleus)-dbs and gpi (globus pallidus internus)-dbs. |
2025-02-12 |
2025-02-14 |
Not clear |
Hutao Xie, Jiansong Huang, Yu Diao, Zixiao Yin, Shu Wang, Quan Zhang, Ming Shan, Houyou Fan, Zhaoting Zheng, Zehua Zhao, Guanyu Zhu, Yin Jiang, Jianguo Zhan. Efficacy comparison and outcome predictors of GPi- and STN-targeted deep brain stimulation for Meige syndrome: a systematic review of individual patient data. Journal of neurosurgery. 2025-01-24. PMID:39854720. |
the aim of this study was to evaluate outcomes of deep brain stimulation (dbs) for meige syndrome, compare the efficacy of globus pallidus internus (gpi) and subthalamic nucleus (stn) as targets, and identify potential outcome predictors. |
2025-01-24 |
2025-01-27 |
Not clear |
Nadja R Ging-Jehli, James F Cavanagh, Minkyu Ahn, David J Segar, Wael F Asaad, Michael J Fran. Basal ganglia components have distinct computational roles in decision-making dynamics under conflict and uncertainty. PLoS biology. vol 23. issue 1. 2025-01-23. PMID:39847590. |
we collected intracranial recordings from patients diagnosed with either parkinson's disease (pd) (n = 14) or dystonia (n = 3) in the subthalamic nucleus (stn), globus pallidus internus (gpi), and globus pallidus externus (gpe) during their performance of a novel perceptual discrimination task in which we independently manipulated uncertainty and conflict. |
2025-01-23 |
2025-01-26 |
human |
Maria Cecilia Fernandez, Ximena Giordano, Waleska Berrios, Licina Barbieri, Agustina Ciceri, Gaston Moreno Milicich, Pablo Vera Cornejo, Carla Stefani, Lucia Ciancaglini, Jose Bestoso, Diego Baus. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 3. 2025-01-03. PMID:39750587. |
however, changes in mood and cognition have been reported after surgical intervention in the subthalamic nucleus (stn) or the internal globus pallidus (gpi), but the literature is inconsistent. |
2025-01-03 |
2025-01-05 |
Not clear |
Obai Yousef, Abdallah Abbas, Maickel Abdelmeseh, Ruaa Mustafa Qafesha, Yehia Nabil, Amr Elrosasy, Ahmed Negida, Brian D Berma. Subthalamic nucleus versus globus pallidus internus deep brain stimulation in the treatment of dystonia: A systematic review and meta-analysis of safety and efficacy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 132. 2024-12-08. PMID:39647323. |
this systematic review and meta-analysis aimed to compare the efficacy and safety of deep brain stimulation (dbs) targeting subthalamic nucleus (stn) versus the globus pallidus internus (gpi) in the treatment of dystonia. |
2024-12-08 |
2024-12-11 |
Not clear |
Makenna Huhn, Matthew Prewett, Julien Rossignol, Gary L Dunba. Comparison of the Long-Term Efficacy of Targeting the Subthalamic Nucleus Versus the Globus Pallidus Interna for Deep Brain Stimulation Treatment of Motor Dysfunction in Patients With Parkinson's Disease: A Meta-Analysis Study. Parkinson's disease. vol 2024. 2024-12-04. PMID:39628904. |
the present study represents a meta-analysis of the long-term (> 5 years) effects of dbs on the two most common targets, the subthalamic nucleus (stn) and the globus pallidus interna (gpi), on scores of motor performance using the updrs-iii. |
2024-12-04 |
2024-12-06 |
Not clear |
Bart E K S Swinnen, Colin W Hoy, Elena Pegolo, Bryony Ishihara, Elena Ubeda Matzilevich, Julia Sun, Francesca Morgante, Erlick Pereira, Fahd Baig, Michael Hart, Huiling Tan, Zimi Sawacha, Martijn Beudel, Sarah Wang, Philip Starr, Simon Little, Lucia Ricciard. Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease. Brain : a journal of neurology. 2024-10-21. PMID:39432676. |
we recorded local field potentials (lfp) from the subthalamic nucleus (stn) or the globus pallidus pars interna (gpi) dbs implants in three pd cohorts: 1) patients with recordings (stn) performed in hospital at rest via perioperatively externalized leads, without active stimulation, both on or off dopaminergic medication; 2) patients with recordings (stn or gpi) performed at home while resting, via a chronically implanted commercially available sensing-enabled neurostimulator (medtronic percepttm device), on dopaminergic medication, with stimulation both on or off; 3) patients with recordings performed at home while engaging in a behavioral task via stn and gpi leads and electrocorticography paddles over premotor cortex connected to an investigational sensing-enabled neurostimulator, on dopaminergic medication, with stimulation both on or off. |
2024-10-21 |
2024-10-24 |
human |
Chunyan Cao, Vladimir Litvak, Shikun Zhan, Wei Liu, Chao Zhang, Bomin Sun, Dianyou Li, Bernadette C M van Wij. Low-beta versus high-beta band cortico-subcortical coherence in movement inhibition and expectation. Neurobiology of disease. 2024-10-04. PMID:39366457. |
beta band oscillations in the sensorimotor cortex and subcortical structures, such as the subthalamic nucleus (stn) and internal pallidum (gpi), are closely linked to motor control. |
2024-10-04 |
2024-10-07 |
human |
Kristin Hageman, Paul Stypulkowski, Scott Stanslask. Characterization of subthalamic nucleus deep brain stimulation evoked resonant neural activity in a large animal model: A pilot study. Brain research. 2024-09-11. PMID:39260788. |
recent reports have described stimulation evoked resonant neural activity (erna) recorded in the subthalamic nucleus (stn) and globus pallidus internus (gpi) of patients during deep brain stimulation (dbs) surgery. |
2024-09-11 |
2024-09-14 |
human |
Srdjan Sumarac, Jinyoung Youn, Conor Fearon, Luka Zivkovic, Prerana Keerthi, Oliver Flouty, Milos Popovic, Mojgan Hodaie, Suneil Kalia, Andres Lozano, William Hutchison, Alfonso Fasano, Luka Milosevi. Clinico-physiological correlates of Parkinson's disease from multi-resolution basal ganglia recordings. NPJ Parkinson's disease. vol 10. issue 1. 2024-09-11. PMID:39261476. |
herein, we analyzed resting-state single-neuron and local field potential (lfp) activities from people with pd who underwent awake deep brain stimulation surgery of the subthalamic nucleus (stn; n = 125) or globus pallidus internus (gpi; n = 44), and correlated rate-based and oscillatory features with updrsiii off-medication subscores. |
2024-09-11 |
2024-09-14 |
Not clear |
Sandra Murcia Carretero, Katrin Petermann, Ines Debove, Deborah Amstutz, Mário Sousa, Julia Waskönig, Andreas Antonios Diamantaras, Gerd Tinkhauser, Andreas Nowacki, Claudio Pollo, Michael Schuepbach, Paul Krack, Martin Lenard Lachenmaye. Quality of Life after Deep Brain Stimulation in Parkinson's Disease: Does the Target Matter? Movement disorders clinical practice. 2024-09-03. PMID:39225548. |
deep brain stimulation (dbs) of the subthalamic nucleus (stn) and globus pallidus internus (gpi) is an accepted therapy for parkinson's disease (pd) with disabling motor complications. |
2024-09-03 |
2024-09-05 |
Not clear |
Rafika Munawara, Asha Rao, Mayank Sharma, Tulika Gupt. Number of serotonergic neurons in the subthalamic nucleus and globus pallidus internus could influence the effects of deep brain stimulation in Parkinson's disease. Clinical anatomy (New York, N.Y.). 2024-07-30. PMID:39076145. |
deep brain stimulation (dbs) of the subthalamic nucleus (stn) or globus pallidus internus (gpi) is a standard treatment for parkinson's disease (pd), with both regions exhibiting similar treatment effectiveness. |
2024-07-30 |
2024-08-02 |
Not clear |
Xinyi Geng, Zhaoyu Quan, Ruili Zhang, Guanyu Zhu, Yingnan Nie, Shouyan Wang, Edmund Rolls, Jianguo Zhang, Li H. Subthalamic and pallidal oscillations and their couplings reflect dystonia severity and improvements by deep brain stimulation. Neurobiology of disease. 2024-06-27. PMID:38936434. |
deep brain stimulation (dbs) targeting the globus pallidus internus (gpi) and subthalamic nucleus (stn) is employed for the treatment of dystonia. |
2024-06-27 |
2024-06-30 |
Not clear |
Jackson N Cagle, Tiberio de Araujo, Kara A Johnson, John Yu, Lauren Fanty, Filipe P Sarmento, Simon Little, Michael S Okun, Joshua K Wong, Coralie de Hemptinn. Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson's disease. Nature communications. vol 15. issue 1. 2024-05-30. PMID:38816390. |
circadian rhythms have been shown in the subthalamic nucleus (stn) in parkinson's disease (pd), but only a few studies have focused on the globus pallidus internus (gpi). |
2024-05-30 |
2024-06-02 |
human |
M Sohail Noor, Alexandra K Steina, Cameron C McIntyr. Dissecting deep brain stimulation evoked neural activity in the basal ganglia. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 21. issue 3. 2024-04-12. PMID:38608373. |
the recent identification of large amplitude evoked potential (ep) oscillations from dbs in the subthalamic nucleus (stn) or globus pallidus internus (gpi) are providing new scientific opportunities to expand understanding of human basal ganglia network activity. |
2024-04-12 |
2024-04-15 |
human |
Xin Wu, Tao Xue, Shiqing Pan, Weikang Xing, Chuanjun Huang, Jianguo Zhang, Guozheng Zha. Pallidal versus subthalamic deep brain stimulation for Meige syndrome: A systematic review and meta-analysis. Heliyon. vol 10. issue 6. 2024-03-21. PMID:38510025. |
globus pallidus internus (gpi) and subthalamic nucleus (stn) are two common deep brain stimulation (dbs) targets. |
2024-03-21 |
2024-03-23 |
Not clear |
Arif Abdulbaki, Johannes C Wöhrle, Christian Blahak, Ralf Weigel, Katja Kollewe, H Holger Capelle, Hansjörg Bäzner, Joachim K Kraus. Somatosensory evoked potentials recorded from DBS electrodes: the origin of subcortical N18. Journal of neural transmission (Vienna, Austria : 1996). 2024-03-08. PMID:38456947. |
we studied 24 patients with dystonia, parkinson's disease, and chronic pain who underwent quadripolar electrode implantation for chronic dbs and recorded median nerve seps from globus pallidus internus (gpi), subthalamic nucleus (stn), thalamic ventral intermediate nucleus (vim), and ventral posterolateral nucleus (vpl) and the centromedian-parafascicular complex (cm-pf). |
2024-03-08 |
2024-03-10 |
Not clear |
Frits van Brenk, Kaila L Stipancic, Andrea H Rohl, Daniel M Corcos, Kris Tjaden, Jeremy D W Greenle. No differential effects of subthalamic nucleus vs. globus pallidus deep brain stimulation in Parkinson's disease: Speech acoustic and perceptual findings. IBRO neuroscience reports. vol 16. 2024-03-01. PMID:38425546. |
deep brain stimulation (dbs) in the subthalamic nucleus (stn) or the globus pallidus interna (gpi) is well-established as a surgical technique for improving global motor function in patients with idiopathic parkinson's disease (pd). |
2024-03-01 |
2024-03-03 |
Not clear |
Jeffrey W Chen, Michael Zargari, Matthew W Cole, Rishabh Gupta, Deeptha Subramanian, Benoit M Dawant, Rui Li, Peter E Konrad, Dario J Englot, Kaltra Dhima, Sarah K Bic. Electrode position and cognitive outcome following deep brain stimulation surgery. Journal of neurosurgery. 2024-02-09. PMID:38335523. |
subthalamic nucleus (stn) and globus pallidus internus (gpi) deep brain stimulation (dbs) effectively treat motor symptoms in parkinson's disease (pd) but may be associated with cognitive and psychiatric changes in some patients. |
2024-02-09 |
2024-02-12 |
Not clear |