| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julia Herrou, Guillaume Mabilleau, Jean-Michel Lecerf, Thierry Thomas, Emmanuel Biver, Julien Pacco. Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity. Calcified tissue international. 2023-11-24. PMID:37999750. |
further studies are needed to investigate the bone impact of glp-1ra, dual- and triple-receptor agonists for glp-1, glucose-dependent insulin releasing polypeptide (gip), and glucagon in pwo. |
2023-11-24 |
2023-11-29 |
Not clear |
| Sara Becerril, Javier A Cienfuegos, Amaia Rodr\\xc3\\xadguez, Victoria Catal\\xc3\\xa1n, Beatriz Ram\\xc3\\xadrez, V\\xc3\\xadctor Valent\\xc3\\xad, Rafael Moncada, Xabier Unamuno, Javier G\\xc3\\xb3mez-Ambrosi, Gema Fr\\xc3\\xbchbec. Single anastomosis duodeno-ileal bypass with sleeve gastrectomy generates sustained improvement of glycemic control compared with sleeve gastrectomy in the diet-induced obese rat model. Journal of physiology and biochemistry. 2023-11-07. PMID:37935948. |
body weight and food intake were weekly monitored, and 6\xc2\xa0weeks after interventions, fasting plasma glucose, oral glucose and insulin tolerance tests, plasma insulin, adiponectin, gip, glp-1, and ghrelin levels were determined.the body weight of sadi-s rats was significantly (p\xe2\x80\x89<\xe2\x80\x890.001) lower as compared to the sham-operated, sg, and pair-fed groups. |
2023-11-07 |
2023-11-20 |
rat |
| Mohammad Mukul Hossain, Juscelino Tovar, Lieselotte Cloetens, Anne Nilsso. Inclusion of Oat Polar Lipids in a Solid Breakfast Improves Glucose Tolerance, Triglyceridemia, and Gut Hormone Responses Postprandially and after a Standardized Second Meal: A Randomized Crossover Study in Healthy Subjects. Nutrients. vol 15. issue 20. 2023-10-30. PMID:37892464. |
test variables (blood glucose, serum insulin, triglyceride (tg), free fatty acids (ffa), ghrelin, glp-1, pyy, and gip) were measured at fasting and repeatedly during the 5.5 h after ingestion of the breakfast. |
2023-10-30 |
2023-11-08 |
human |
| Mona Mashayekhi, Hui Nian, Dustin Mayfield, Jessica K Devin, Jorge L Gamboa, Chang Yu, Heidi J Silver, Kevin Niswender, James M Luther, Nancy J Brow. Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes. Diabetes. 2023-10-24. PMID:37874653. |
sitagliptin increased endogenous glp-1 and gip without altering insulin sensitivity or fasting glucose, but decreased post-prandial glucose and glucagon. |
2023-10-24 |
2023-11-08 |
Not clear |
| Jing Xu, Peng Chen, Dongzhi Wu, Qiang Zhou, Sijie Chen, Xiang Ding, Hongping Xion. The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway. Aging. vol 15. 2023-10-18. PMID:37851373. |
da3-ch is a novel dual receptor agonist of glucagon like peptide-1 (glp-1) and glucose dependent insulin stimulating polypeptide (gip). |
2023-10-18 |
2023-11-08 |
rat |
| Nan Wu, Guohua A. A Quantitative Systems Pharmacology Model of the Incretin Hormones GIP and GLP1, Glucagon, Glucose, Insulin, and the Small Molecule DPP-4 Inhibitor, Linagliptin. Journal of pharmaceutical sciences. 2023-09-16. PMID:37716531. |
in the current study, we established a comprehensive quantitative systems pharmacology (qsp) model using linagliptin as the model drug, where drug disposition, drug intervention on dipeptidyl peptidase-4 (dpp-4), glucose-dependent insulinotropic peptide (gip), glucagon-like peptide-1 (glp-1), glucagon, glucose, and insulin are integrated together with the cross talk and feedback loops incorporated among the whole glycemic control system. |
2023-09-16 |
2023-10-07 |
human |
| Pamela Bowman, Kashyap A Patel, Timothy J McDonald, Jens J Holst, Bolette Hartmann, Maria Leveridge, Beverley M Shields, Suzie Hammersley, Steve R Spaull, Bridget A Knight, Sarah E Flanagan, Maggie H Shepherd, Rob C Andrews, Andrew T Hattersle. Incretin hormone responses to carbohydrate and protein/fat are preserved in adults with sulfonylurea-treated KCNJ11 neonatal diabetes. Journal of diabetes investigation. 2023-08-21. PMID:37602910. |
the incretin hormones glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip), are thought to be the main drivers of insulin secretion in individuals with sulfonylurea (su)-treated kcnj11 permanent neonatal diabetes. |
2023-08-21 |
2023-09-07 |
human |
| Stine Smedegaard, Ulla Kampmann, Per G Ovesen, Henrik St\\xc3\\xb8vring, Nikolaj Ritti. Whey Protein Premeal Lowers Postprandial Glucose Concentrations in Adults Compared with Water-The Effect of Timing, Dose, and Metabolic Status: a Systematic Review and Meta-analysis. The American journal of clinical nutrition. vol 118. issue 2. 2023-08-03. PMID:37536867. |
the underlying mechanisms are only partly understood but may involve stimulation of glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic polypeptide (gip), and insulin secretion together with a slower gastric emptying rate. |
2023-08-03 |
2023-08-14 |
Not clear |
| Danielle L Jones, Clive J Petry, Keith Burling, Peter Barker, Elizabeth H Turner, Laura C Kusinski, Claire L Mee. Pregnancy glucagon-like peptide 1 predicts insulin but not glucose concentrations. Acta diabetologica. 2023-07-13. PMID:37439859. |
incretin hormones glucagon-like peptide 1 (glp-1) and gastric inhibitory peptide (gip) cause increased insulin secretion in non-pregnant adults, but their role in pregnancy, where there are additional metabolically-active hormones from the placenta, is less clear. |
2023-07-13 |
2023-08-14 |
Not clear |
| Aaron Hengist, Christina M Sciarrillo, Juen Guo, Mary Walter, Kevin D Hal. Discordance between gut-derived appetite hormones and energy intake in humans. medRxiv : the preprint server for health sciences. 2023-07-10. PMID:37425848. |
ghrelin increases hunger and decreases after food intake, whereas satiation and satiety are induced by peptide yy (pyy), glucagon-like peptide-1 (glp-1), and perhaps glucose-dependent insulinotropic polypeptide (gip) which are increased after food intake [1-3]. |
2023-07-10 |
2023-08-14 |
Not clear |
| Kimberley El, Jonathan D Douros, Francis S Willard, Aaron Novikoff, Ashot Sargsyan, Diego Perez-Tilve, David B Wainscott, Bin Yang, Alex Chen, Donald Wothe, Callum Coupland, Mattias H Tsch\\xc3\\xb6p, Brian Finan, David A D'Alessio, Kyle W Sloop, Timo D M\\xc3\\xbcller, Jonathan E Campbel. The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets. Nature metabolism. 2023-06-05. PMID:37277609. |
the incretins glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide 1 (glp-1) mediate insulin responses that are proportionate to nutrient intake to facilitate glucose tolerance |
2023-06-05 |
2023-08-14 |
human |
| Gaber El-Saber Batiha, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Nada A Ashour, Walaa A Neg. Potential role of tirzepatide towards Covid-19 infection in diabetic patients: a perspective approach. Inflammopharmacology. 2023-05-19. PMID:37208555. |
the beneficial effect of tzt in t2dm and obesity is related to direct activation of gip and glp-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight. |
2023-05-19 |
2023-08-14 |
Not clear |
| Daniel J Drucker, Jens J Hols. The expanding incretin universe: from basic biology to clinical translation. Diabetologia. 2023-03-28. PMID:36976349. |
incretin hormones, principally glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1(glp-1), potentiate meal-stimulated insulin secretion through direct (gip + glp-1) and indirect (glp-1) actions on islet \xce\xb2-cells. |
2023-03-28 |
2023-08-14 |
Not clear |
| Bo Ahr\\xc3\\xa9. Contribution of GIP and GLP-1 to the Insulin Response to Oral Administration of Glucose in Female Mice. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831127. |
contribution of gip and glp-1 to the insulin response to oral administration of glucose in female mice. |
2023-02-25 |
2023-08-14 |
mouse |
| Bo Ahr\\xc3\\xa9. Contribution of GIP and GLP-1 to the Insulin Response to Oral Administration of Glucose in Female Mice. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831127. |
now, i have proceeded and studied the contribution of glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) to the insulin response to oral glucose in female mice by using receptor antagonists. |
2023-02-25 |
2023-08-14 |
mouse |
| Jaros\\xc5\\x82aw Nuszkiewicz, Jolanta Czuczejko, Wiktor Dr\\xc3\\xb3\\xc5\\xbcd\\xc5\\xbc, Alina Wo\\xc5\\xbaniak, Bogdan Ma\\xc5\\x82kowski, Karolina Szewczyk-Gole. Concentration of Selected Adipokines and Factors Regulating Carbohydrate Metabolism in Patients with Head and Neck Cancer in Respect to Their Body Mass Index. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36834693. |
the aim of the study was to determine the concentrations of ghrelin, omentin-1, adipsin, adiponectin, leptin, resistin, visfatin, glucagon, insulin, c-peptide, glucagon-like peptide-1 (glp-1), plasminogen activator inhibitor-1 (pai-1), and gastric inhibitory peptide (gip) in the blood serum of hnc patients depending on their body mass index (bmi). |
2023-02-25 |
2023-08-14 |
Not clear |
| Reema Abu Khalaf, Ebtisam Alwarafi, Dima Sabba. Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and Acta pharmaceutica (Zagreb, Croatia). vol 71. issue 4. 2023-01-18. PMID:36651550. |
dipeptidyl peptidase-iv (dpp-iv) inhibitors minimize glucagon and blood glucose levels by increasing the incretin levels, glucagon-like peptide (glp-1) and glucose-dependent insulinotropic poly-peptide (gip), leading to insulin secretion from pancreatic beta cells. |
2023-01-18 |
2023-08-14 |
Not clear |
| Giovanni Targher, Alessandro Mantovani, Christopher D Byrn. Mechanisms and possible hepatoprotective effects of glucagon-like peptide-1 receptor agonists and other incretin receptor agonists in non-alcoholic fatty liver disease. The lancet. Gastroenterology & hepatology. vol 8. issue 2. 2023-01-09. PMID:36620987. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are incretins that stimulate insulin secretion from pancreatic \xce\xb2 cells in response to food ingestion. |
2023-01-09 |
2023-08-14 |
Not clear |
| Nanna Thurmann J\\xc3\\xb8rgensen, Trine M\\xc3\\xb8ller Erichsen, Morten Buus J\\xc3\\xb8rgensen, Thomas Idorn, Bo Feldt-Rasmussen, Jens J Holst, Ulla Feldt-Rasmussen, Marianne Klos. Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis. Pituitary. 2023-01-07. PMID:36609655. |
the objective of the study was to describe the differential effect of various treatment regimens on the secretion of glucose, insulin, glucagon, glucagon-like peptide-1 (glp-1), and glucose-dependent insulinotropic polypeptide (gip) in patients with acromegaly. |
2023-01-07 |
2023-08-14 |
Not clear |
| Ioannis G Lempesis, Junli Liu, Maria Dalamag. The Metabolism open. vol 16. 2022-12-19. PMID:36530219. |
glp-1 and gip exert pleiotropic physiological actions, including enhancement of insulin secretion, glycemic and appetite control, cardioprotection, and adipose tissue improved function among others. |
2022-12-19 |
2023-08-14 |
Not clear |