| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aman Nikhil, Mudasir B Gugjoo, Ankita Das, Syed M Ahmad, Ashok Kuma. 3D-Printed-Cryogel-Impregnated Functionalized Scaffold Augments Bone Regeneration in Critical Tibia Fracture in Goat. Advanced healthcare materials. 2024-10-01. PMID:39350449. |
histology showed significant cell infiltration and matrix deposition over the printed p─p─h scaffold and within the gh cryogel site in the treatment group. |
2024-10-01 |
2024-10-03 |
rat |
| Maria Danielma Dos Santos Reis, Luciana Peixoto Veneziani, Felipe Lima Porto, Marvin Paulo Lins, Daniella Arêas Mendes-da-Cruz, Wilson Savin. Intrathymic somatotropic circuitry: consequences upon thymus involution. Frontiers in immunology. vol 14. 2023-07-10. PMID:37426675. |
interestingly, gh, igf-1, ghrelin, and somatostatin are expressed in the thymus in the lymphoid and microenvironmental compartments, where they stimulate the secretion of soluble factors and extracellular matrix molecules involved in the general process of intrathymic t-cell development. |
2023-07-10 |
2023-08-14 |
Not clear |
| Wei Ji, Fei Han, Xian Feng, Lei Shi, Hongdong Ma, Yue Lu, Ran Ta. Cocktail-like gradient gelatin/hyaluronic acid bioimplant for enhancing tendon-bone healing in fatty-infiltrated rotator cuff injury models. International journal of biological macromolecules. 2023-06-17. PMID:37330074. |
as collagen and hyaluronic acid are the main biomacromolecules that constitute the extracellular matrix of enthesis tissue, this hydrogel was composed of uv-curable gelatin/hyaluronic acid (gelma/hama) dual network gel (gh) with nanoclay (nc) and stem cells loaded. |
2023-06-17 |
2023-08-14 |
Not clear |
| Yu Zhu, Yi Sun, Biyu Rui, Junqing Lin, Junjie Shen, Huimin Xiao, Xuanzhe Liu, Yimin Chai, Jia Xu, Yunlong Yan. A Photoannealed Granular Hydrogel Facilitating Hyaline Cartilage Regeneration via Improving Chondrogenic Phenotype. ACS applied materials & interfaces. 2022-09-02. PMID:36052731. |
further in vivo studies of subcutaneous culture and the rat full-thickness cartilage defect model proved that chondrocyte loaded gh could significantly stimulate hyaline cartilage matrix deposition and connection, therefore facilitating hyaline-like cartilage regeneration. |
2022-09-02 |
2023-08-14 |
rat |
| Min Jae Kan. Novel genetic cause of idiopathic short stature. Annals of pediatric endocrinology & metabolism. vol 22. issue 3. 2020-10-01. PMID:29025200. |
in addition, recent studies have shown that many factors, including paracrine signals, extracellular matrix, and intracellular mechanisms of chondrocytes, regulate the growth plate independent of the gh - igf-i system. |
2020-10-01 |
2023-08-13 |
Not clear |
| M Kužma, Z Killinger, P Jackuliak, P Vaňuga, D Hans, N Binkley, J Paye. Pathophysiology of growth hormone secretion disorders and their impact on bone microstructure as measured by trabecular bone score. Physiological research. vol 68. issue Suppl 2. 2020-05-01. PMID:31842575. |
gh, via receptor activator of nuclear factor-kappab (rank), its ligand (rank-l), and the osteoprotegerin system, stimulates production of osteoprotegerin and its accumulation in bone matrix. |
2020-05-01 |
2023-08-13 |
Not clear |
| Jan M. Wit, Asma Deeb, Bassam Bin-Abbas, Angham Al Mutair, Ekaterina Koledova, Martin O. Savag. Achieving Optimal Short- and Long-term Responses to Paediatric Growth Hormone Therapy Journal of clinical research in pediatric endocrinology. vol 11. issue 4. 2020-04-14. PMID:31284701. |
genetic discoveries have ranged from defects of pituitary development and gh action to abnormalities in intracellular mechanisms, paracrine regulation and cartilage matrix formation. |
2020-04-14 |
2023-08-13 |
human |
| Darlene E Berryman, Brooke Henry, Rikke Hjortebjerg, Edward O List, John J Kopchic. Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic. Expert review of endocrinology & metabolism. vol 11. issue 2. 2019-11-20. PMID:28435436. |
at depot-specific alterations in immune cells, extracellular matrix, adipokines, and senescence indicate an expanded role for gh in at physiology. |
2019-11-20 |
2023-08-13 |
mouse |
| Zipeng Li, Hidetoshi Masumoto, Jun-Ichiro Jo, Kazuhiro Yamazaki, Tadashi Ikeda, Yasuhiko Tabata, Kenji Minatoy. Sustained release of basic fibroblast growth factor using gelatin hydrogel improved left ventricular function through the alteration of collagen subtype in a rat chronic myocardial infarction model. General thoracic and cardiovascular surgery. vol 66. issue 11. 2018-12-11. PMID:29982930. |
here we aimed to testify the therapeutic effects of sustained release of basic fibroblast growth factor (bfgf) using gelatin hydrogel (gh) in a rat chronic mi model and to elucidate the therapeutic mechanism including the alteration of extracellular matrix component. |
2018-12-11 |
2023-08-13 |
rat |
| Maria Danielma Dos Santos Reis, Yngrid Mickaelli Oliveira Dos Santos, Clarice Agudo de Menezes, Karen Steponavicius Cruz Borbely, Salete Smaniott. Resident murine macrophage migration and phagocytosis are modulated by growth hormone. Cell biology international. vol 42. issue 5. 2018-09-10. PMID:29363842. |
herein, we showed that in vivo gh treatment resulted in decreased expression of vla-5 and vla-6 integrins on the macrophage surface, accompanied by a reduction in macrophage adhesion to extracellular matrix (ecm) ligands, fibronectin, and laminin. |
2018-09-10 |
2023-08-13 |
mouse |
| Rehab Abdelmonem, Mohamed El Nabarawi, Alshaimaa Atti. Development of novel bioadhesive granisetron hydrochloride spanlastic gel and insert for brain targeting and study their effects on rats. Drug delivery. vol 25. issue 1. 2018-07-24. PMID:29228824. |
gelatin and hpmc as matrix former, glycine as a collapse protecting and mannitol as an insert filler and sweeting agent were used to prepare gh spanlastic loaded in lyophilized inserts (ghspnis). |
2018-07-24 |
2023-08-13 |
rat |
| M Victoria Recouvreux, J Boyang Wu, Allen C Gao, Svetlana Zonis, Vera Chesnokova, Neil Bhowmick, Leland W Chung, Shlomo Melme. Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells. Endocrinology. vol 158. issue 7. 2017-09-29. PMID:28444169. |
we also show that gh enhances invasive behavior of crpc 22rv1 cells, as reflected by increased migration, invasion, and anchorage-independent growth, as well as expression of matrix metalloproteases. |
2017-09-29 |
2023-08-13 |
human |
| P Swathi Chitra, T Swathi, Rakesh Sahay, G Bhanuprakash Reddy, Ram K Menon, P Anil Kuma. Growth Hormone Induces Transforming Growth Factor-Beta-Induced Protein in Podocytes: Implications for Podocyte Depletion and Proteinuria. Journal of cellular biochemistry. vol 116. issue 9. 2016-05-10. PMID:25740786. |
to elucidate the molecular basis for the effects of gh on podocyte depletion, we conducted pcr-array analyses for extracellular matrix and adhesion molecules in podocytes. |
2016-05-10 |
2023-08-13 |
rat |
| Jeffrey Baron, Lars Sävendahl, Francesco De Luca, Andrew Dauber, Moshe Phillip, Jan M Wit, Ola Nilsso. Short and tall stature: a new paradigm emerges. Nature reviews. Endocrinology. vol 11. issue 12. 2016-03-21. PMID:26437621. |
consequently, normal growth in children depends not only on gh and igf-1 but also on multiple hormones, paracrine factors, extracellular matrix molecules and intracellular proteins that regulate the activity of growth plate chondrocytes. |
2016-03-21 |
2023-08-13 |
Not clear |
| Gilbert E Wieringa, Catharine M Sturgeon, Peter J Traine. The harmonisation of growth hormone measurements: taking the next steps. Clinica chimica acta; international journal of clinical chemistry. vol 432. 2015-01-15. PMID:24509000. |
the establishment of an international harmonisation oversight group is recommended: its key roles to include identification of a commutable matrix reference material, assessing the clinical significance of assay interferents, the evaluation of liquid chromatography-mass spectrometry as a reference measurement procedure and the provision of acceptance criteria for the clinical application of gh methods. |
2015-01-15 |
2023-08-12 |
Not clear |
| A P Boesen, K Dideriksen, C Couppé, S P Magnusson, P Schjerling, M Boesen, P Aagaard, M Kjaer, H Langber. Effect of growth hormone on aging connective tissue in muscle and tendon: gene expression, morphology, and function following immobilization and rehabilitation. Journal of applied physiology (Bethesda, Md. : 1985). vol 116. issue 2. 2014-09-30. PMID:24235105. |
in conclusion, in elderly humans, gh seems to have a matrix stabilizing effect during inactivity and rehabilitation by stimulating collagen expression in the musculotendinous tissue and increasing tendon csa and stiffness. |
2014-09-30 |
2023-08-12 |
human |
| Neethu Ninan, Muthunarayanan Muthiah, In-Kyu Park, Anne Elain, Tin Wui Wong, Sabu Thomas, Yves Grohen. Faujasites incorporated tissue engineering scaffolds for wound healing: in vitro and in vivo analysis. ACS applied materials & interfaces. vol 5. issue 21. 2014-06-16. PMID:24102066. |
the pore size of gelatin/ha scaffold was 50-2000 μm, whereas it was greatly reduced to 10-250 μm after incorporation of 2.4% (w/w) of faujasites in polymer matrix, gh(2.4%). |
2014-06-16 |
2023-08-12 |
rat |
| Jabrullah Ab Hamid, Norhafizah Mohtarrudin, Malina Osman, Andi Anggeriana Andi Asri, Wan Hamilton Wan Hassan, Rohani Azi. Matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases 1 and 2 as potential biomarkers for gestational hypertension. Singapore medical journal. vol 53. issue 10. 2013-12-10. PMID:23112021. |
a cluster of enzymes, called matrix metalloproteinases (mmps), and its specific inhibitors, tissue inhibitors of metalloproteinases (timps), have been reported to be involved in the pathophysiology of gh. |
2013-12-10 |
2023-08-12 |
Not clear |
| A E Rigamonti, M Bozzola, G Banfi, C Meazza, E E Müller, S G Cell. Growth hormone variants: a potential avenue for a better diagnostic characterization of growth hormone deficiency in children. Journal of endocrinological investigation. vol 35. issue 10. 2013-05-28. PMID:23027770. |
however, other factors are involved: a) interference from endogenous gh binding proteins; b) different specificities of anti- gh (monoclonal and polyclonal) antibodies; c) different matrix effects among the calibrators; d) the use of different calibrators. |
2013-05-28 |
2023-08-12 |
human |
| C Meazza, R Albertini, S Pagani, N Sessa, K Laarej, R Falcone, E Bozzola, V Calcaterra, M Bozzol. Diagnosis of growth hormone deficiency is affected by calibrators used in GH immunoassays. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 44. issue 12. 2013-04-22. PMID:22674475. |
growth hormone (gh) values vary among immunoassays depending on different factors, such as the assay method used, specificity of antibodies, matrix difference between standards and samples, and interference with endogenous gh binding proteins (ghbps). |
2013-04-22 |
2023-08-12 |
human |