| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyan Hu, Shuang Liu, Zhang Jing, Yuxiao He, Gang Qin, Liang Jian. Immunomodulation in allergic rhinitis: Insights from Th2 cells and NLRP3/IL-18 pathway. Cell biochemistry and function. vol 42. issue 3. 2024-03-31. PMID:38555506. |
following ova stimulation, increased nasal symptoms were observed in the ova group along with augmented gata3 expression and elevated il-4 and il-1b levels, indicative of th2 polarization and cellular pyroptosis involvement. |
2024-03-31 |
2024-04-02 |
mouse |
| Yunxiu Wang, Zhiwei Cao, He Zhao, Zhaowei G. Nonylphenol exacerbates ovalbumin-induced allergic rhinitis via the TSLP-TSLPR/IL-7R pathway and JAK1/2-STAT3 signaling in a mouse model. Ecotoxicology and environmental safety. vol 243. 2022-08-27. PMID:36029577. |
the levels of the typical t helper 2 cytokines, as well as the mrna levels of ox40/ox40l and gata3, were elevated in the nasal mucosa of ova-challenged mice exposed to np. |
2022-08-27 |
2023-08-14 |
mouse |
| Yunxiu Wang, Zhiwei Cao, He Zhao, Zhaowei G. Nonylphenol exacerbates ovalbumin-induced allergic rhinitis via the TSLP-TSLPR/IL-7R pathway and JAK1/2-STAT3 signaling in a mouse model. Ecotoxicology and environmental safety. vol 243. 2022-08-27. PMID:36029577. |
the mrna levels of ox40/ox40l and gata3 in nasal mucosa were detected by qpcr, and the expression levels of the tslp and jak1/2-stat3 signaling pathway components were also identified. |
2022-08-27 |
2023-08-14 |
mouse |
| Jianguo Liu, Xunshuo Jiang, Lihua Li, Hongbing Liu, Xiana Zhang, Ke Liu, Chunping Yan. Iloprost inhibits acute allergic nasal inflammation by GATA3 -ILC2 pathway in mice. Respiratory physiology & neurobiology. vol 276. 2021-10-05. PMID:31899354. |
iloprost inhibits acute allergic nasal inflammation by gata3 -ilc2 pathway in mice. |
2021-10-05 |
2023-08-13 |
mouse |
| Xia Li, Zhiyuan Wang, Lihong Chang, Xiaohong Chen, Luoying Yang, Xiaoping Lai, Shuaixiang Li, Jiancong Huang, Zizhen Huang, Xifu Wu, Joseph A Bellanti, Song Guo Zheng, Gehua Zhan. γδT cells contribute to type 2 inflammatory profiles in eosinophilic chronic rhinosinusitis with nasal polyps. Clinical science (London, England : 1979). vol 133. issue 22. 2020-05-26. PMID:31722010. |
moreover, inflammatory markers including type 2 proinflammatory cytokines (il-4, il-5, il-13), gata3, eosinophil cationic protein (ecp), and eotaxin levels were also increased in nasal tissues of patients with ecrs, and vγ1+ γδt cells mrna expression was positively correlated with type 2 cytokines, gata3, and ecp. |
2020-05-26 |
2023-08-13 |
human |
| Xia Li, Zhiyuan Wang, Lihong Chang, Xiaohong Chen, Luoying Yang, Xiaoping Lai, Shuaixiang Li, Jiancong Huang, Zizhen Huang, Xifu Wu, Joseph A Bellanti, Song Guo Zheng, Gehua Zhan. γδT cells contribute to type 2 inflammatory profiles in eosinophilic chronic rhinosinusitis with nasal polyps. Clinical science (London, England : 1979). vol 133. issue 22. 2020-05-26. PMID:31722010. |
in the ecrs murine model, anti-vγ1+ γδt antibody treatment reduced the infiltration of eosinophils and expression of type 2 cytokines, gata3, and ecp in nasal mucosae. |
2020-05-26 |
2023-08-13 |
human |
| Z Chen, Y Deng, F Li, B Xiao, X Zhou, Z Ta. MicroRNA-466a-3p attenuates allergic nasal inflammation in mice by targeting GATA3. Clinical and experimental immunology. vol 197. issue 3. 2020-05-06. PMID:31081939. |
microrna-466a-3p attenuates allergic nasal inflammation in mice by targeting gata3. |
2020-05-06 |
2023-08-13 |
mouse |
| Tanja Kosak Soklic, Matija Rijavec, Mira Silar, Ana Koren, Izidor Kern, Irena Hocevar-Boltezar, Peter Korose. Transcription factors gene expression in chronic rhinosinusitis with and without nasal polyps. Radiology and oncology. vol 53. issue 3. 2020-03-23. PMID:31326962. |
in crssnp, we unexpectedly found simultaneous upregulation of t-bet and gata3 that is currently unexplained; however, it might originate from activated cd8+ cells, abundant in nasal mucosa of crssnp patients. |
2020-03-23 |
2023-08-13 |
Not clear |
| Thi Tho Bui, Chun Hua Piao, Chang Ho Song, Ok Hee Cha. Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release. International immunopharmacology. vol 52. 2018-06-12. PMID:28886581. |
ova-induced ar mice increased nasal symptoms, eosinophils and mast cells infiltration into nasal cavity, ova-specific ige/igg1 and histamine in serum, th2 cytokines including il-13 and gata3, and nf-κb signaling in nalf and lung homogenate. |
2018-06-12 |
2023-08-13 |
mouse |
| Zhao Wei Gu, Yun Xiu Wang, Zhi Wei Ca. Neutralization of interleukin-9 ameliorates symptoms of allergic rhinitis by reducing Th2, Th9, and Th17 responses and increasing the Treg response in a murine model. Oncotarget. vol 8. issue 9. 2017-10-09. PMID:28187441. |
we measured nasal rubbing motion, sneezing and eosinophils, as well as the th1 (th1 cell percentage, ifn-γ mrna/protein, t-bet mrna), th2 (th2 cell percentage, il-4 mrna/protein, gata3 mrna), th9 (th9 cell percentages il-9 mrna/protein, pu.1 and irf4 mrna), th17 (th17 cell percentage, il-17 mrna/protein, rorγt mrna), and treg (treg cell percentage, foxp3 mrna) responses in the nasal mucosa. |
2017-10-09 |
2023-08-13 |
mouse |
| Jenny Mjösberg, Jochem Bernink, Korneliusz Golebski, Julien J Karrich, Charlotte P Peters, Bianca Blom, Anje A te Velde, Wytske J Fokkens, Cornelis M van Drunen, Hergen Spit. The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity. vol 37. issue 4. 2012-12-27. PMID:23063330. |
nasal polyp epithelial cells expressed tslp, which enhanced stat5 activation, gata3 expression, and type 2 cytokine production in ilc2s. |
2012-12-27 |
2023-08-12 |
human |