| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela G Correas, Gloria Olaso-Gonzalez, Marta Roca, Mari Carmen Blanco-Gandía, Carla Nascimento, Agustin Lahoz, Marta Rodriguez-Arias, José Miñarro, Mari Carmen Gomez-Cabrera, José Viñ. Glucose 6 phosphate dehydrogenase overexpression rescues the loss of cognition in the double transgenic APP/PS1 mouse model of Alzheimer's disease. Redox biology. vol 75. 2024-06-22. PMID:38908073. |
the cognitive decline characteristic of app/ps1 mice was prevented in 3xtg g6pd mice, despite similar amyloid-β (aβ) levels in the hippocampus. |
2024-06-22 |
2024-06-25 |
mouse |
| Daria Ponomareva, Anton Ivanov, Piotr Bregestovsk. Analysis of the Effects of Pentose Phosphate Pathway Inhibition on the Generation of Reactive Oxygen Species and Epileptiform Activity in Hippocampal Slices. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339211. |
using the specific g6pd inhibitor g6pdi-1, we assessed its effects on mouse hippocampal slices, examining intracellular ros, glucose/oxygen consumption, the nad(p)h level and ros production during synaptic stimulation and in the 4ap epilepsy model. |
2024-02-10 |
2024-02-12 |
mouse |
| Wenjuan Zhou, Yuan Yao, Jinxing Li, Dong Wu, Man Zhao, Zongting Yan, Aimei Pang, Liang Kon. TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis Frontiers in molecular neuroscience. vol 12. 2020-09-29. PMID:31456661. |
in this study, we observed that tigar and g6pd are decreased in the hippocampus of streptozotocin (stz)-induced diabetic mice. |
2020-09-29 |
2023-08-13 |
mouse |
| Oleg Vetrovoy, Kseniia Sarieva, Olga Galkina, Natalia Eschenko, Andrey Lyanguzov, Tatjana Gluschenko, Ekaterina Tyulkova, Elena Rybnikov. Neuroprotective Mechanism of Hypoxic Post-conditioning Involves HIF1-Associated Regulation of the Pentose Phosphate Pathway in Rat Brain. Neurochemical research. vol 44. issue 6. 2019-06-11. PMID:30448928. |
we have observed that sh leads to a decrease of glucose-6-phosphate dehydrogenase (g6pd) activity in the hippocampus and neocortex of rats as well as to a reduction in nadph and total glutathione levels. |
2019-06-11 |
2023-08-13 |
rat |
| Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, Shogo Matsuyam. The influence of chronic nicotine treatment on proteins expressed in the mouse hippocampus and cortex. European journal of pharmacology. vol 780. 2017-03-06. PMID:26988295. |
there was significant change in the expression of 16 proteins and one phosphoprotein in the hippocampus (increased tubulin β-5, atp5b, mdh1, cytochrome b-c1 complex subunit 1, hsc70, dynamin, profilin-2, 4-aminobutyrate aminotransferase, mitochondrial isoform 1 precursor, calpain small subunit 1, and vacuolar adenosine triphosphatase subunit b and decreased γ-actin, α-tubulin isotype m-α-2, putative β-actin, tubulin β-2a, ndufa10, and g6pd) and 24 proteins and two phosphoproteins in the cortex (increased spectrin α chain, non-erythrocytic 1 isoform 1, tubulin β-5, γ-actin, creatine kinase b-type, ldh-b, secernin-1, uch-l1, 14-3-3 γ, type ii peroxiredoxin 1, pebp-1, and unnamed protein product and decreased tubulin α-1c, α-internexin, γ-enolase, pdhe1-b, dpyl2, vacuolar adenosine triphosphatase subunit a, vacuolar adenosine triphosphatase subunit b, tctp, nadh dehydrogenase fe-s protein 1, protein disulfide-isomerase a3, hnrnp h2, γ-actin, atp5b, and unnamed protein product). |
2017-03-06 |
2023-08-13 |
mouse |
| Winnie Jeng, Margaret M Loniewska, Peter G Well. Brain glucose-6-phosphate dehydrogenase protects against endogenous oxidative DNA damage and neurodegeneration in aged mice. ACS chemical neuroscience. vol 4. issue 7. 2013-11-25. PMID:23672460. |
dna oxidation was increased in g6pd(def/def) mice in the cortex (p < 0.02), hippocampus (p < 0.01) and cerebellum (p < 0.006) compared to g6pd(+/+) mice, and was localized to distinct cell types. |
2013-11-25 |
2023-08-12 |
mouse |
| Rachna Agarwal, Abdelhaq Ram. Redistribution of glucose-6-phosphate dehydrogenase in response to cerebral ischemia in rat brain. Indian journal of clinical biochemistry : IJCB. vol 18. issue 2. 2012-10-30. PMID:23105394. |
ischemia induced up-regulation of g6pd in the hippocampus was in a specific manner. |
2012-10-30 |
2023-08-12 |
rat |
| Rachna Agarwal, Abdelhaq Ram. Redistribution of glucose-6-phosphate dehydrogenase in response to cerebral ischemia in rat brain. Indian journal of clinical biochemistry : IJCB. vol 18. issue 2. 2012-10-30. PMID:23105394. |
the redistribution of g6pd in the hippocampus was studied post-ischemia (pi). |
2012-10-30 |
2023-08-12 |
rat |
| Rachna Agarwal, Abdelhaq Ram. Redistribution of glucose-6-phosphate dehydrogenase in response to cerebral ischemia in rat brain. Indian journal of clinical biochemistry : IJCB. vol 18. issue 2. 2012-10-30. PMID:23105394. |
there was a characteristic localisation of g6pd in pyramidal cell layers of the rat hippocampus. |
2012-10-30 |
2023-08-12 |
rat |
| Yanling Zhao, Xiaoli Pan, Jing Zhao, Yang Wang, Yun Peng, Chunjiu Zhon. Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency. Journal of neurochemistry. vol 111. issue 2. 2009-10-22. PMID:19686241. |
the activities of pyruvate dehydrogenase (pdh), alpha-ketoglutamate dehydrogenase (kgdh), glucose-6-phosphate dehydrogenase (g6pd), and transketolase (tk), as well as on the contents of nadp(+) and nadph were determined in whole mouse brain, isolated cortex, and hippocampus of td mice model. |
2009-10-22 |
2023-08-12 |
mouse |
| Yanling Zhao, Xiaoli Pan, Jing Zhao, Yang Wang, Yun Peng, Chunjiu Zhon. Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency. Journal of neurochemistry. vol 111. issue 2. 2009-10-22. PMID:19686241. |
the results showed that td specifically reduced tk activity in both cortex and hippocampus, without significantly affecting the activities of pdh, kgdh, and g6pd in td9 and td14 groups. |
2009-10-22 |
2023-08-12 |
mouse |
| M A Philbert, C M Beiswanger, T L Roscoe, D K Waters, H E Lownde. Enhanced resolution of histochemical distribution of glucose-6-phosphate dehydrogenase activity in rat neural tissue by use of a semipermeable membrane. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 39. issue 7. 1991-09-06. PMID:1865111. |
hippocampal pyramidal and granular cells of the dentate gyrus exhibited moderate, uniform g6pd activity, but only weak activity was seen in hippocampal and dentate molecular layers. |
1991-09-06 |
2023-08-11 |
rat |