| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F Page, Lindsay Liang, David M Young, Athena R Ypsilanti, Matthew W State, Alex S Nord, Stephan J Sanders, John L R Rubenstei. Five autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes. Cell reports. vol 43. issue 6. 2024-06-08. PMID:38850535. |
chromatin immunoprecipitation sequencing (chip-seq) was used to identify the regulatory targets of arid1b, bcl11a, foxp1, tbr1, and tcf7l2, asd-associated trs in the developing human and mouse cortex. |
2024-06-08 |
2024-06-11 |
mouse |
| Marissa Co, Ashley G Anderson, Genevieve Konopk. FOXP transcription factors in vertebrate brain development, function, and disorders. Wiley interdisciplinary reviews. Developmental biology. vol 9. issue 5. 2021-10-11. PMID:31999079. |
here, foxp1, foxp2, and foxp4 are expressed in distinct cell type-specific spatiotemporal patterns in multiple regions, including the cortex, hippocampus, amygdala, basal ganglia, thalamus, and cerebellum. |
2021-10-11 |
2023-08-13 |
human |
| Caroline Alayne Pearson, Destaye M Moore, Haley O Tucker, Joseph D Dekker, Hui Hu, Amaya Miquelajáuregui, Bennett G Novitc. Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell reports. vol 30. issue 6. 2021-03-08. PMID:32049024. |
foxp1 expression is further associated with the initial formation and expansion of basal rg (brg) during human corticogenesis and can promote the formation of cells exhibiting characteristics of brg when misexpressed in the mouse cortex. |
2021-03-08 |
2023-08-13 |
mouse |
| Xue Li, Xin Han, Xiaomeng Tu, Dan Zhu, Yue Feng, Tian Jiang, Youping Yang, Jia Qu, Jie-Guang Che. An Autism-Related, Nonsense Foxp1 Mutant Induces Autophagy and Delays Radial Migration of the Cortical Neurons. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 7. 2020-09-28. PMID:30124790. |
disruptions of foxp1, a transcription factor expressed in the developing cerebral cortex, were associated with asd. |
2020-09-28 |
2023-08-13 |
mouse |
| Weng Lam Fong, Hsiao-Ying Kuo, Hsiao-Lin Wu, Shih-Yun Chen, Fu-Chin Li. Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain. Neuroscience. vol 388. 2019-03-29. PMID:30031127. |
moreover, none of parvalbumin-, somatostatin-, nnos-, and calretinin-positive interneurons co-expressed foxp1 or foxp2 in the cerebral cortex. |
2019-03-29 |
2023-08-13 |
mouse |
| Henning Fröhlich, Rafiullah Rafiullah, Nathalie Schmitt, Sonja Abele, Gudrun A Rappol. Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization. Human molecular genetics. vol 26. issue 8. 2017-05-15. PMID:28204507. |
we further analyzed foxp1 and foxp2 expression in the striatum and cortex of cd1 mice at different embryonic and postnatal stages and observed sex differences in both genes at e17.5 and p7.5. |
2017-05-15 |
2023-08-13 |
mouse |
| Henning Fröhlich, Rafiullah Rafiullah, Nathalie Schmitt, Sonja Abele, Gudrun A Rappol. Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization. Human molecular genetics. vol 26. issue 8. 2017-05-15. PMID:28204507. |
we show that foxp1 and the androgen receptor are co-expressed in striatal medium spiny neurons and that brain-specific androgen receptor ko (arnescre) mice exhibit reduced foxp1 expression in the striatum at e17.5 and p7.5 and an increased foxp2 level in the cortex at p7.5. |
2017-05-15 |
2023-08-13 |
mouse |
| Henning Fröhlich, Rafiullah Rafiullah, Nathalie Schmitt, Sonja Abele, Gudrun A Rappol. Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization. Human molecular genetics. vol 26. issue 8. 2017-05-15. PMID:28204507. |
as expression differences of foxp1 or foxp2 could explain the sex-dimorphic vocalization in wt animals, we quantified both proteins in the striatum and cortex at p7.5 and detected a sex-specific expression of foxp2 in the striatum. |
2017-05-15 |
2023-08-13 |
mouse |
| Xue Li, Jian Xiao, Henning Fröhlich, Xiaomeng Tu, Lianlian Li, Yue Xu, Huateng Cao, Jia Qu, Gudrun A Rappold, Jie-Guang Che. Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PloS one. vol 10. issue 5. 2016-04-21. PMID:26010426. |
mice with foxp1 knockdown exhibited ectopic neurons in deep layers of the cortex postnatally. |
2016-04-21 |
2023-08-13 |
mouse |
| Xue Li, Jian Xiao, Henning Fröhlich, Xiaomeng Tu, Lianlian Li, Yue Xu, Huateng Cao, Jia Qu, Gudrun A Rappold, Jie-Guang Che. Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PloS one. vol 10. issue 5. 2016-04-21. PMID:26010426. |
foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. |
2016-04-21 |
2023-08-13 |
mouse |
| Xue Li, Jian Xiao, Henning Fröhlich, Xiaomeng Tu, Lianlian Li, Yue Xu, Huateng Cao, Jia Qu, Gudrun A Rappold, Jie-Guang Che. Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PloS one. vol 10. issue 5. 2016-04-21. PMID:26010426. |
here, we report that suppression of foxp1 expression in mouse cerebral cortex led to a neuronal migration defect, which was rescued by overexpression of foxp1. |
2016-04-21 |
2023-08-13 |
mouse |
| J Michael Bowers, Miguel Perez-Pouchoulen, Clinton R Roby, Timothy E Ryan, Margaret M McCarth. Androgen modulation of Foxp1 and Foxp2 in the developing rat brain: impact on sex specific vocalization. Endocrinology. vol 155. issue 12. 2015-07-08. PMID:25247470. |
androgen effects on both foxp2 and foxp1 were found to occur in the striatum, cerebellar vermis, and cortex. |
2015-07-08 |
2023-08-13 |
human |
| Qianqian Chen, Jonathan B Heston, Zachary D Burkett, Stephanie A Whit. Expression analysis of the speech-related genes FoxP1 and FoxP2 and their relation to singing behavior in two songbird species. The Journal of experimental biology. vol 216. issue Pt 19. 2014-04-07. PMID:24006346. |
notably, the transcription factors forkhead box proteins 1 and 2 (foxp1, foxp2) exhibit similar expression patterns in the cortex and basal ganglia of humans and the zebra finch species of songbird, among other brain regions. |
2014-04-07 |
2023-08-12 |
Not clear |
| T Hisaoka, Y Nakamura, E Senba, Y Morikaw. The forkhead transcription factors, Foxp1 and Foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20040367. |
although both foxp1 and foxp2 are expressed in the neural circuits that mediate speech and language, including the corticostriatal circuit, the functions of foxp1 and foxp2 in the cerebral cortex remain unclear. |
2010-05-03 |
2023-08-12 |
mouse |
| T Hisaoka, Y Nakamura, E Senba, Y Morikaw. The forkhead transcription factors, Foxp1 and Foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20040367. |
the forkhead transcription factors, foxp1 and foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex. |
2010-05-03 |
2023-08-12 |
mouse |
| T Hisaoka, Y Nakamura, E Senba, Y Morikaw. The forkhead transcription factors, Foxp1 and Foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20040367. |
to gain insight into the functions of foxp1 and foxp2 in the cerebral cortex, we characterized foxp1- and foxp2-expressing cells in postnatal and adult mice using immunohistochemistry. |
2010-05-03 |
2023-08-12 |
mouse |
| T Hisaoka, Y Nakamura, E Senba, Y Morikaw. The forkhead transcription factors, Foxp1 and Foxp2, identify different subpopulations of projection neurons in the mouse cerebral cortex. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20040367. |
foxp1 and foxp2, which belong to the forkhead transcription factor family, are expressed in the developing and adult mouse brain, including the striatum, thalamus, and cerebral cortex. |
2010-05-03 |
2023-08-12 |
mouse |
| Y Morikawa, T Hisaoka, E Senb. Characterization of Foxp2-expressing cells in the developing spinal cord. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19463901. |
two members of winged-helix/forkhead transcription factors, foxp1 and foxp2, are expressed in the developing and adult cns, including the striatum, cerebral cortex, and thalamus. |
2009-11-10 |
2023-08-12 |
mouse |
| S Tamura, Y Morikawa, H Iwanishi, T Hisaoka, E Senb. Foxp1 gene expression in projection neurons of the mouse striatum. Neuroscience. vol 124. issue 2. 2004-06-01. PMID:14980377. |
foxp1 was highly expressed in the striatum and moderately in the cerebral cortex, ca1/2 subfields of the hippocampus, and several thalamic nuclei. |
2004-06-01 |
2023-08-12 |
mouse |
| Russell J Ferland, Timothy J Cherry, Patricia O Preware, Edward E Morrisey, Christopher A Wals. Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain. The Journal of comparative neurology. vol 460. issue 2. 2003-06-04. PMID:12687690. |
foxp1 expression was observed in the cerebral cortex (layers 3-5), hippocampus (ca1), and thalamus. |
2003-06-04 |
2023-08-12 |
mouse |