| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Breyanna L Cavanaugh, Michelle L Milstein, R Casey Boucher, Sharon X Tan, Mario W Hanna, Adam Seidel, Rikard Frederiksen, Thomas L Saunders, Alapakkam P Sampath, Kenneth P Mitton, Dao-Qi Zhang, Andrew F X Goldber. A new mouse model for PRPH2 pattern dystrophy exhibits functional compensation prior and subsequent to retinal degeneration. Human molecular genetics. 2024-09-04. PMID:39231530. |
young (p21) prph2y285x/wt mice developed near-normal photoreceptor numbers; however, os membrane architecture was disrupted, os protein levels were reduced, and in vivo and ex vivo electroretinography (erg) analyses found that rod and cone photoreceptor function were each severely reduced. |
2024-09-04 |
2024-09-08 |
mouse |
| Mikhail Kulyabin, Aleksei Zhdanov, Andreas Maier, Lynne Loh, Jose J Estevez, Paul A Constabl. Generating Synthetic Light-Adapted Electroretinogram Waveforms Using Artificial Intelligence to Improve Classification of Retinal Conditions in Under-Represented Populations. Journal of ophthalmology. vol 2024. 2024-07-24. PMID:39045382. |
the full-field flash electroretinogram (erg) assesses the global contribution of the outer and inner retinal layers initiated by the rods and cone pathways depending on the state of retinal adaptation. |
2024-07-24 |
2024-07-26 |
human |
| Tomoko Sato, Kazuki Kuniyoshi, Takaaki Hayashi, Hirokazu Nishiwaki, Kei Mizobuchi, Shunji Kusak. Clinical course of two siblings with potassium voltage-gated channel modifier subfamily V member 2 (KCNV2)-associated retinopathy. Documenta ophthalmologica. Advances in ophthalmology. 2024-04-17. PMID:38630375. |
kcnv2-associated retinopathy causes a phenotype reported as "cone dystrophy with nyctalopia and supernormal rod responses (cdsrr; omim# 610356)," featuring pathognomonic findings on electroretinography (erg). |
2024-04-17 |
2024-04-19 |
Not clear |
| Qing-An Ding, Chunyan Liu, Fangfang Ning, Xiaoyuan Li, Binghui Hou, Yuhua Gao, Jianyu Li, Chaoran G. Investigating the ERG a-wave and Retinal Diseases with Rod Equivalent Circuit Model Based on the APD. Biophysical journal. 2024-03-13. PMID:38475997. |
moreover, the typical waveform characteristics of two retinal diseases, the enhanced short wavelength sensitivity (sws) cone syndrome and retinitis pigmentosa (rp), are investigated on the basis of electroretinogram (erg) a-wave. |
2024-03-13 |
2024-03-15 |
Not clear |
| Chengjie He, Jingyi Peng, Jiayi Jin, Wanwen Shao, Yongxin Zheng, Liuxueying Zhon. Comparison of retinal parameters between rhesus and cynomolgus macaques. Experimental animals. vol 73. issue 1. 2024-02-14. PMID:37460311. |
dark-adapted 3.0 oscillatory potentials (reflection of amacrine cell activity) and light-adapted 30-hz flicker erg (a sensitive cone-pathway-driven response) waveforms of the ff-erg were similar in both species, while the times to peaks in dark-adapted 0.01 erg (the rod-driven response of bipolar cells) and dark-adapted 3.0 erg (combined rod and cone system responses) as well as the implicit times of the a- and b-waves in light-adapted 3.0 erg (the single-flash cone response) were substantially different. |
2024-02-14 |
2024-02-17 |
monkey |
| Alex Diamond, Steven Silverstein, Brian Kean. Poster Session: Visual System Assessment for Predicting a Transition to Psychosis. Journal of vision. vol 23. issue 11. 2023-09-21. PMID:37733533. |
promising retinal markers include reduced cone a- and b-wave amplitudes and photopic negative response (erg). |
2023-09-21 |
2023-10-07 |
Not clear |
| Yunlu Xue, Xiaomei Sun, Sean K Wang, Gayle B Collin, Vladimir J Kefalov, Constance L Cepk. Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 23. 2023-05-31. PMID:37252956. |
using physiological assays, we investigated the timing of cone electroretinogram (erg) decline in rp mouse models. |
2023-05-31 |
2023-08-14 |
mouse |
| Yunlu Xue, Xiaomei Sun, Sean K Wang, Gayle B Collin, Vladimir J Kefalov, Constance L Cepk. Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 23. 2023-05-31. PMID:37252956. |
a correlation between the time of loss of the cone erg and the loss of rods was found. |
2023-05-31 |
2023-08-14 |
mouse |
| Chong Chen, Yu Rong, Youyuan Zhuang, Cheng Tang, Qian Liu, Peng Lin, Dandan Li, Xinyi Zhao, Fan Lu, Jia Qu, Xinting Li. RNA-Seq Analysis Reveals an Essential Role of the cGMP-PKG-MAPK Pathways in Retinal Degeneration Caused by Cep250 Deficiency. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240188. |
after recording the erg responses and oct images at p90 and p180, the cone and rod photoreceptors were visualised using an immunofluorescent stain. |
2023-05-27 |
2023-08-14 |
mouse |
| Jaime E Brown, Breanna Aldred, Tyler Boulter, Rachel Sullivan, James Ver Hoeve, Bikash R Pattnaik, Melanie Schmit. A case report of retinal dystrophy in patients with PACS1 syndrome. Ophthalmic genetics. 2023-05-23. PMID:37218682. |
the first patient is a 14-month-old female who, at 3 months of age, was found to have a depressed rod and cone response on electroretinogram (erg), consistent with possible retinal dystrophy (rd). |
2023-05-23 |
2023-08-14 |
Not clear |
| Xiao Li, Zhilin Jiang, Yujing Su, Kaifang Wang, Xiaoyan Jiang, Kuanxiang Sun, Yeming Yang, Yu Zhou, Xianjun Zhu, Lin Zhan. Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice. The FEBS journal. 2023-04-26. PMID:37098815. |
here, we show that emc1 ablation in the photoreceptor cells of mice recapitulated the retinitis pigmentosa (rp) phenotypes, including an attenuated scotopic electroretinogram (erg) response and the progressive degeneration of rod cells and cone cells. |
2023-04-26 |
2023-08-14 |
mouse |
| Ryo Mukai, Yuki Tajika, Kazuma Saito, Hideo Akiyam. Micro-abnormalities in the retina and choroid induced by anti-CTLA4 treatment. Scientific reports. vol 13. issue 1. 2023-04-18. PMID:37072549. |
on erg, rod, maximum responses of combined rods and cones, and cone response wave amplitudes were significantly reduced in treated mice. |
2023-04-18 |
2023-08-14 |
mouse |
| Monika Modrzejewska, Wojciech Lubiński, Katarzyna Czyżewska, Wiktoria Bosy-Gąsio. Observations for Sjögren's Pigment Epithelial Reticular Dystrophy in a 16-Year-Old Boy-An Extremely Rare Retinal Case Report. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835943. |
multifocal erg (mferg) revealed slight cone photoreceptor and bipolar bioelectrical dysfunction. |
2023-02-25 |
2023-08-14 |
Not clear |
| Monika Modrzejewska, Wojciech Lubiński, Katarzyna Czyżewska, Wiktoria Bosy-Gąsio. Observations for Sjögren's Pigment Epithelial Reticular Dystrophy in a 16-Year-Old Boy-An Extremely Rare Retinal Case Report. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835943. |
flash erg (erg) revealed only slight increase in implicit time of the a and b waves of the rod and cone responses and exclude cone-rod dystrophies. |
2023-02-25 |
2023-08-14 |
Not clear |
| Zeki Baysal, Hamidu Hamisi Gobek. Electrophysiological Evaluation of Macular Photoreceptor Functions in Patients with Choroidal Neovascular Membranes. Current eye research. 2022-12-16. PMID:36524692. |
to evaluate changes in cone functions using light-adapted (la) 30hz flicker and la 3.0 electroretinography (erg) in intravitreal ranibizumab (ivr)-treated naïve neovascular age-related macular degeneration (namd) patients. |
2022-12-16 |
2023-08-14 |
Not clear |
| Nate Pasmanter, Simon M Petersen-Jone. Characterization of scotopic and mesopic rod signaling pathways in dogs using the On-Off electroretinogram. BMC veterinary research. vol 18. issue 1. 2022-12-03. PMID:36463174. |
depending on degree of dark-adaptation and stimulus strength the on and off erg can be shaped by rod and cone photoreceptors and postreceptoral cells, including on and off bipolar cells. |
2022-12-03 |
2023-08-14 |
dog |
| Jared D Chrispell, Yubin Xiong, Ellen R Weis. Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP. The Journal of biological chemistry. 2022-10-23. PMID:36273582. |
erg analyses of larvae treated with forskolin show that elevated intracellular camp significantly decreases recovery of the cone photoresponse, which is mediated by grk7a rather than grk1b. |
2022-10-23 |
2023-08-14 |
mouse |
| You Wang, Li Huang, Limei Sun, Songshan Li, Zhaotian Zhang, Ting Zhang, Yanting Lai, Xiaoyan Din. Ocular findings and genetic test in Alström syndrome in childhood. Experimental eye research. 2022-10-07. PMID:36206858. |
electroretinograms (erg) demonstrated severely diminished cone and rod responses. |
2022-10-07 |
2023-08-14 |
human |
| Sara K Mayer, Jacintha Thomas, Megan Helms, Aishwarya Kothapalli, Ioana Cherascu, Adisa Salesevic, Elliot Stalter, Kai Wang, Poppy Datta, Charles Searby, Seongjin Seo, Ying Hsu, Sajag Bhattarai, Val C Sheffield, Arlene V Drac. Knockout of Bbs10 results in lack of cone electrical function and progressive retinal degeneration of rods and cones. Disease models & mechanisms. 2022-09-20. PMID:36124545. |
cone erg was absent from at least p30, at which time rod erg was reduced to 74.4% of control levels; at eight months rod erg was 2.3% of controls. |
2022-09-20 |
2023-08-14 |
mouse |
| Sara K Mayer, Jacintha Thomas, Megan Helms, Aishwarya Kothapalli, Ioana Cherascu, Adisa Salesevic, Elliot Stalter, Kai Wang, Poppy Datta, Charles Searby, Seongjin Seo, Ying Hsu, Sajag Bhattarai, Val C Sheffield, Arlene V Drac. Progressive retinal degeneration of rods and cones in a Bardet-Biedl syndrome type 10 mouse model. Disease models & mechanisms. vol 15. issue 9. 2022-09-20. PMID:36125046. |
cone erg was absent from at least p30, at which time rod erg was reduced to 74.4% of control levels; at 8 months, rod erg was 2.3% of that of controls. |
2022-09-20 |
2023-08-14 |
mouse |