All Relations between elovl4 and purkinje

Publication Sentence Publish Date Extraction Date Species
Jennifer L Fessler, Megan A Stiles, Martin-Paul Agbaga, Mohiuddin Ahmad, David M Sherr. The Spinocerebellar Ataxia 34-Causing W246G ELOVL4 Mutation Does Not Alter Cerebellar Neuron Populations in a Rat Model. Cerebellum (London, England). 2024-06-08. PMID:38850484. to test whether w246g elovl4 altered neuronal generation or survival in the cerebellum, we compared the numbers of purkinje cells, unipolar brush cells, molecular layer interneurons, granule and displaced granule cells in the cerebellum of wildtype, heterozygous, and homozygous sca34-ki rats at four months of age, when motor impairment is already present. 2024-06-08 2024-06-11 human
Raghavendra Y Nagaraja, David M Sherry, Jennifer L Fessler, Megan A Stiles, Feng Li, Karanpreet Multani, Albert Orock, Mohiuddin Ahmad, Richard S Brush, Robert E Anderson, Martin-Paul Agbaga, Ferenc Deá. W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34227061. to understand the mechanism of these motor deficits, we performed electrophysiological studies using cerebellar slices from rats homozygous for w246g mutant elovl4 and found marked reduction of long-term potentiation at parallel fiber synapses and long-term depression at climbing fiber synapses onto purkinje cells. 2021-10-27 2023-08-13 rat