| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jared P Schober, Kevin B Ginsburg, Alexander Kutikov, Eric Y Cho, Matt Loecher, David Strauss, Alberto Andres Castro Bigalli, Elizabeth Handorf, Mengying Deng M Math, Jordan Anaokar, David Yt Chen, Richard E Greenberg, Marc C Smaldone, Rosalia Viterbo, Andres F Correa, Robert G Uzzo, Marshall Strothe. Real-time Estimation of Nephron Activity with a Linear Measurement System (RENAL-MS) Predicts Postoperative eGFR. BJU international. 2023-09-05. PMID:37667554. |
real-time estimation of nephron activity with a linear measurement system (renal-ms) predicts postoperative egfr. |
2023-09-05 |
2023-09-07 |
Not clear |
| Paul Vergnaud, Camille Cohen, Pierre Isnar. [Towards understanding chronic kidney disease]. Medecine sciences : M/S. vol 39. issue 3. 2023-03-21. PMID:36943124. |
the physiopathology of ckd progression is unclear but some hypotheses have been described: i) the nephron "overwork", supported by recent works showing that the nephron reduction leads to hyperfiltration by the remaining nephrons and the stability of the gfr; ii) the "podocyte adaptation" theory, reflected by the importance of the podocytopathy in ckd progression and the crucial role of residual proteinuria in renal lesion development; iii) the activation of egfr signaling pathways in surgical nephron reduction model and its involvement in ckd progression. |
2023-03-21 |
2023-08-14 |
Not clear |
| Dana Bielopolski, Elani Streja, Tali Steinmetz, Benaya Rozen-Zvi, Kamyar Kalantar-Zade. Novel insights in classic versus relative glomerular hyperfiltration and implications on pharmacotherapy. Current opinion in nephrology and hypertension. vol 32. issue 1. 2022-11-29. PMID:36444663. |
current egfr formulae are indexed for standardized body surface area (bsa) of 1.73 m2, ignoring persons and populations wherein the ratio of bsa or metabolic rate to nephron number might be different, due to increased bsa, increased metabolic rate or reduced nephron number. |
2022-11-29 |
2023-08-14 |
Not clear |
| Go Kanzaki, Victor G Puelles, Luise A Cullen-McEwen, Wendy E Hoy, Yusuke Okabayashi, Nobuo Tsuboi, Akira Shimizu, Kate M Denton, Michael D Hughson, Takashi Yokoo, John F Bertra. New insights on glomerular hyperfiltration: a Japanese autopsy study. JCI insight. vol 2. issue 19. 2019-07-29. PMID:28978800. |
we estimated total nephron (glomerular) number (nglomtotal) as well as numbers of nonsclerosed (nglomnsg) and globally sclerosed glomeruli (nglomgsg), and the mean volume of nonsclerosed glomeruli (vglomnsg) in japanese normotensive, hypertensive, and ckd subjects and investigated associations between these parameters and estimated glomerular filtration rate (egfr). |
2019-07-29 |
2023-08-13 |
human |
| Andrew P Morris, Thu H Le, Haojia Wu, Artur Akbarov, Peter J van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J Gaulton, Girish N Nadkarni, Adan Valladares-Salgado, Niels Wacher-Rodarte, Josyf C Mychaleckyj, Nicole D Dueker, Xiuqing Guo, Yang Hai, Jeffrey Haessler, Yoichiro Kamatani, Adrienne M Stilp, Gu Zhu, James P Cook, Johan Ärnlöv, Susan H Blanton, Martin H de Borst, Erwin P Bottinger, Thomas A Buchanan, Sylvia Cechova, Fadi J Charchar, Pei-Lun Chu, Jeffrey Damman, James Eales, Ali G Gharavi, Vilmantas Giedraitis, Andrew C Heath, Eli Ipp, Krzysztof Kiryluk, Holly J Kramer, Michiaki Kubo, Anders Larsson, Cecilia M Lindgren, Yingchang Lu, Pamela A F Madden, Grant W Montgomery, George J Papanicolaou, Leslie J Raffel, Ralph L Sacco, Elena Sanchez, Holger Stark, Johan Sundstrom, Kent D Taylor, Anny H Xiang, Aleksandra Zivkovic, Lars Lind, Erik Ingelsson, Nicholas G Martin, John B Whitfield, Jianwen Cai, Cathy C Laurie, Yukinori Okada, Koichi Matsuda, Charles Kooperberg, Yii-Der Ida Chen, Tatjana Rundek, Stephen S Rich, Ruth J F Loos, Esteban J Parra, Miguel Cruz, Jerome I Rotter, Harold Snieder, Maciej Tomaszewski, Benjamin D Humphreys, Nora Franceschin. Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. Nature communications. vol 10. issue 1. 2019-02-19. PMID:30604766. |
fine-mapping reveals 40 high-confidence variants driving egfr associations and highlights putative causal genes with cell-type specific expression in glomerulus, and in proximal and distal nephron. |
2019-02-19 |
2023-08-13 |
Not clear |
| Y Kandasamy, R Smith, I M R Wright, E R Lumber. Reduced nephron endowment in the neonates of Indigenous Australian peoples. Journal of developmental origins of health and disease. vol 5. issue 1. 2015-01-14. PMID:24847688. |
despite a smaller kidney volume (and reduced nephron number), indigenous neonates did not have a significantly lower egfr. |
2015-01-14 |
2023-08-13 |
Not clear |
| Carolyn L Abitbol, Wacharee Seeherunvong, Marta G Galarza, Chryso Katsoufis, Denise Francoeur, Marissa Defreitas, Alcia Edwards-Richards, Vimal Master Sankar Raj, Jayanthi Chandar, Shahnaz Duara, Salih Yasin, Gaston Zilleruel. Neonatal kidney size and function in preterm infants: what is a true estimate of glomerular filtration rate? The Journal of pediatrics. vol 164. issue 5. 2014-06-02. PMID:24607244. |
to distinguish between cystatin c (cysc) and creatinine (cr) as markers of estimated glomerular filtration rate (egfr) in preterm infants and to correlate egfr with total kidney volume (tkv) as a surrogate of nephron mass. |
2014-06-02 |
2023-08-12 |
Not clear |
| Denise Laouari, Martine Burtin, Aurélie Phelep, Frank Bienaime, Laure-Hélène Noel, David C Lee, Christophe Legendre, Gérard Friedlander, Marco Pontoglio, Fabiola Terz. A transcriptional network underlies susceptibility to kidney disease progression. EMBO molecular medicine. vol 4. issue 8. 2012-12-07. PMID:22711280. |
we have recently shown that the susceptibility to development of renal lesions after nephron reduction is controlled by a locus on mouse chromosome 6 and requires epidermal growth factor receptor (egfr) activation. |
2012-12-07 |
2023-08-12 |
mouse |
| Daniel Canter, Alexander Kutikov, Mohit Sirohi, Ryan Street, Rosalia Viterbo, David Y T Chen, Richard E Greenberg, Robert G Uzz. Prevalence of baseline chronic kidney disease in patients presenting with solid renal tumors. Urology. vol 77. issue 4. 2011-07-04. PMID:21316090. |
egfr and chronic kidney disease ckd stage are more clinically relevant parameters to reflect the risk of morbidity and mortality in patients after nephron loss. |
2011-07-04 |
2023-08-12 |
Not clear |
| Amandine Viau, Khalil El Karoui, Denise Laouari, Martine Burtin, Clément Nguyen, Kiyoshi Mori, Evangéline Pillebout, Thorsten Berger, Tak Wah Mak, Bertrand Knebelmann, Gérard Friedlander, Jonathan Barasch, Fabiola Terz. Lipocalin 2 is essential for chronic kidney disease progression in mice and humans. The Journal of clinical investigation. vol 120. issue 11. 2010-12-07. PMID:20921623. |
we recently showed that the severity of renal lesions after nephron reduction varied substantially among mouse strains and required activation of egfr. |
2010-12-07 |
2023-08-12 |
mouse |
| Gérard Friedlander, Fabiola Terz. [Angiotensin and EGF receptor cross-talk in chronic kidney diseases: towards a new therapeutic approach]. Bulletin de l'Academie nationale de medecine. vol 190. issue 4-5. 2007-03-09. PMID:17195617. |
we show that transgenic mice harboring a dominant negative form of egfr are resistant to the progression of renal lesions induced by nephron reduction or angiotensin infusion. |
2007-03-09 |
2023-08-12 |
mouse |