| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aleksandra Antos, Agnieszka Topolska-Woś, Marcin Woś, Agata Mitura, Paulina Sarzyńska, Tomasz Lipiński, Andrzej Kurylcio, Piotr Ziółkowski, Marta Świtalska, Joanna Tkaczuk-Włach, Andrzej Gamian, Wojciech P Polkowski, Magdalena Staniszewsk. The unique monoclonal antibodies and immunochemical assay for comprehensive determination of the cell-bound and soluble HER2 in different biological samples. Scientific reports. vol 14. issue 1. 2024-02-17. PMID:38368450. |
however, a soluble extracellular domain (ecd) of her2 is released to the extracellular matrix, thus the blood assays for her2 measurements present an attractive way for her2 level determination. |
2024-02-17 |
2024-02-20 |
human |
| Gianluigi Albano, Lorenzo Portus, Elisa Martinelli, Gennaro Pescitelli, Lorenzo Di Bar. Impact of Temperature on the Chiroptical Properties of Thin Films of Chiral Thiophene-based Oligomers. ChemPlusChem. 2024-02-10. PMID:38339881. |
according to the theoretical model based on the mueller matrix approach, the experimental electronic circular dichroism (ecd) for thin films of chiral organic dyes can be expressed as the sum of several contributions, two of which are the most significant: 1) an intrinsic component (cdiso) invariant upon sample orientation, reflecting the molecular and/or supramolecular chirality, due to 3d-chiral nanoscopic structures; 2) a non-reciprocal component (ldlb) which inverts its sign upon sample flipping, which arises from the interaction of linear dichroism and linear birefringence in locally anisotropic domains, expression of 2d-chiral micro/mesoscopic structures. |
2024-02-10 |
2024-02-12 |
Not clear |
| Massimiliano Aschi, Laura Palombi, Andrea Amade. Theoretical-Computational Modeling of CD Spectra of Aqueous Monosaccharides by Means of Molecular Dynamics Simulations and Perturbed Matrix Method. Molecules (Basel, Switzerland). vol 28. issue 8. 2023-04-28. PMID:37110825. |
the electronic circular dichroism (ecd) spectra of aqueous d-glucose and d-galactose were modeled using a theoretical-computational approach combining molecular dynamics (md) simulations and perturbed matrix method (pmm) calculations, hereafter termed md-pmm. |
2023-04-28 |
2023-08-14 |
Not clear |
| Ru Xu, Peixuan Cheng, Kaili Meng, Linkang Li, Meizhi Jiao, Xue Zhao, Pu Jia, Xiaohui Zheng, Chaoni Xia. Extracellular domain of human calcium sensing receptor immobilized to silica beads as biomaterial: A rapid chromatographic method for recognizing ligands from complex matrix 'Shuangdan'. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1208. 2022-08-11. PMID:35952444. |
herein, extracellular domain (ecd) of casr as its functional fragment was used to develop a rapid chromatographic method, which involved the synthesis of stationary phase material based on the site-specific covalent reaction of halogenated alkane dehalogenase (halo)-tagged ecd of casr in cell lysate with 6-chlorocaproic acid modified silica beads, the use of the immobilized casr column for revealing the interaction of three known agonists with casr and further screening ligands from complex matrix like chinese herb medicine 'shuangdan'. |
2022-08-11 |
2023-08-14 |
human |
| Wei Li, Liang-Jun Jiang, Xiao-Jun Zhou, Xian-Zhou Lu, Long-Fei Liu, Song Wan. Association of the invasiveness of colon cancer with the expression of C/EBPα. Oncology letters. vol 17. issue 2. 2020-09-30. PMID:30675263. |
in addition, the expression levels of tumor invasion-associated proteins, including kruppel-like factor 5 (klf5), matrix metallopeptidase (mmp)-2, mmp-9, and e-cadherin (ecd) were detected subsequent to transfection. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chunli Wang, Siyao Wang, Songcai Liu, Yunyun Cheng, Hongwei Geng, Rui Yang, Tianqi Feng, Guanhong Lu, Xiaotong Sun, Jie Song, Linlin Ha. Synonymous Mutations of Porcine Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32754602. |
the insulin-like growth factor 1 receptor (igf-1r), which receives signals through the extracellular domain (ecd) binding with ligands, is crucial in regulating cell growth and bone matrix mineralization. |
2020-09-28 |
2023-08-13 |
Not clear |
| Tingting Li, Jin'e Liu, Hao Cai, Baomei Wang, Yunfeng Feng, Jun Li. Incorporation of DDR2 clusters into collagen matrix via integrin-dependent posterior remnant tethering. International journal of biological sciences. vol 14. issue 6. 2019-06-11. PMID:29904280. |
although the oligomerization of ddr extracellular domain (ecd) proteins can affect matrix remodeling by inhibiting fibrillogenesis, it is still unknown how cellular ddr2 is incorporated into collagen matrix. |
2019-06-11 |
2023-08-13 |
Not clear |
| Tekleweini Gereslassie, Ababo Workineh, Onyango Janet Atieno, Jun Wan. Determination of Occurrences, Distribution, Health Impacts of Organochlorine Pesticides in Soils of Central China. International journal of environmental research and public health. vol 16. issue 1. 2019-05-28. PMID:30621114. |
sample extraction was carried out by solid phase matrix extraction method and analyzed using agilent gas chromatograph 7890b equipped with electron capture detectors (ecd). |
2019-05-28 |
2023-08-13 |
Not clear |
| Daniele Padula, Lorenzo Di Bari, Gennaro Pescitell. The "Case of Two Compounds with Similar Configuration but Nearly Mirror Image CD Spectra" Refuted. Reassignment of the Absolute Configuration of N-Formyl-3',4'-dihydrospiro[indan-1,2'(1'H)-pyridine]. The Journal of organic chemistry. vol 81. issue 17. 2018-05-16. PMID:27463608. |
the main reason for the observed failure is the use of the matrix method, a popular approach to predict ecd spectra of compounds which can be treated with an independent system approximation (isa), including proteins. |
2018-05-16 |
2023-08-13 |
Not clear |
| Moses O Oyewumi, Dharani Manickavasagam, Kimberly Novak, Daniel Wehrung, Nikola Paulic, Fouad M Moussa, Gregory R Sondag, Fayez F Safad. Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells. Oncotarget. vol 7. issue 12. 2017-12-15. PMID:26883195. |
meanwhile, sirna-mediated knockdown of gpnmb/oa in cancer cells significantly reduced gpnmb/oa ecd protein shedding, migration, invasion and adhesion to extracellular matrix materials. |
2017-12-15 |
2023-08-13 |
human |
| Xiangnan Li, Fangyu Zhu, Yongsong He, Fang Lu. [Arginase inhibitor nor-NOHA induces apoptosis and inhibits invasion and migration of HepG2 cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 33. issue 4. 2017-09-14. PMID:28395717. |
the protein levels of arginase 1 (arg1), p53, matrix metalloproteinase-2 (mmp-2), e-cadherin (ecd) were determined by western blotting. |
2017-09-14 |
2023-08-13 |
Not clear |
| Carmen Capone, Emmanuel Cognat, Lamia Ghezali, Céline Baron-Menguy, Déborah Aubin, Laurent Mesnard, Heidi Stöhr, Valérie Domenga-Denier, Mark T Nelson, Anne Joute. Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice. Annals of neurology. vol 79. issue 3. 2016-07-19. PMID:26648042. |
timp3 and vitronectin are 2 extracellular matrix proteins that abnormally accumulate in notch3(ecd) -containing deposits on brain vessels of mice and patients with cadasil. |
2016-07-19 |
2023-08-13 |
mouse |
| Xiaohong Zhang, Xianxiang Xu, Tao Xu, Si Qi. β-Ecdysterone suppresses interleukin-1β-induced apoptosis and inflammation in rat chondrocytes via inhibition of NF-κB signaling pathway. Drug development research. vol 75. issue 3. 2014-12-18. PMID:24648308. |
il-1β-induced inflammation and matrix degration were also prevented by ecd via down-regulation of matrix metalloproteinases mmp 3, mmp 9, and cyclooxygenase-2 expression. |
2014-12-18 |
2023-08-12 |
rat |
| Marie Monet-Leprêtre, Iman Haddad, Céline Baron-Menguy, Maï Fouillot-Panchal, Meriem Riani, Valérie Domenga-Denier, Claire Dussaule, Emmanuel Cognat, Joelle Vinh, Anne Joute. Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL. Brain : a journal of neurology. vol 136. issue Pt 6. 2013-08-07. PMID:23649698. |
further proteomic and immunohistochemical analyses identified two functionally important extracellular matrix proteins, tissue inhibitor of metalloproteinases 3 (timp3) and vitronectin (vtn) that are sequestered into notch3(ecd)-containing aggregates. |
2013-08-07 |
2023-08-12 |
mouse |
| Marie Monet-Leprêtre, Iman Haddad, Céline Baron-Menguy, Maï Fouillot-Panchal, Meriem Riani, Valérie Domenga-Denier, Claire Dussaule, Emmanuel Cognat, Joelle Vinh, Anne Joute. Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL. Brain : a journal of neurology. vol 136. issue Pt 6. 2013-08-07. PMID:23649698. |
specifically, our results suggest a dysregulation of timp3 activity, which could contribute to mutant notch3(ecd) toxicity by impairing extracellular matrix homeostasis in small vessels. |
2013-08-07 |
2023-08-12 |
mouse |
| Marie Monet-Leprêtre, Iman Haddad, Céline Baron-Menguy, Maï Fouillot-Panchal, Meriem Riani, Valérie Domenga-Denier, Claire Dussaule, Emmanuel Cognat, Joelle Vinh, Anne Joute. Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL. Brain : a journal of neurology. vol 136. issue Pt 6. 2013-08-07. PMID:23649698. |
abnormal recruitment of extracellular matrix proteins by excess notch3 ecd: a new pathomechanism in cadasil. |
2013-08-07 |
2023-08-12 |
mouse |
| Marie Monet-Leprêtre, Iman Haddad, Céline Baron-Menguy, Maï Fouillot-Panchal, Meriem Riani, Valérie Domenga-Denier, Claire Dussaule, Emmanuel Cognat, Joelle Vinh, Anne Joute. Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL. Brain : a journal of neurology. vol 136. issue Pt 6. 2013-08-07. PMID:23649698. |
collectively, our findings lend support to a notch3(ecd) cascade hypothesis in cadasil disease pathology, which posits that aggregation/accumulation of notch3(ecd) in the brain vessels is a central event, promoting the abnormal recruitment of functionally important extracellular matrix proteins that may ultimately cause multifactorial toxicity. |
2013-08-07 |
2023-08-12 |
mouse |
| Carlos Spuch, Saida Ortolano, Carmen Navarr. LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease. Frontiers in physiology. vol 3. 2012-10-02. PMID:22934024. |
through its ecd, lrps bind at least 40 different ligands ranging from lipoprotein and protease inhibitor complex to growth factors and extracellular matrix proteins. |
2012-10-02 |
2023-08-12 |
Not clear |
| Yi Luo, Hitoshi Ohmori, Kiyomu Fujii, Yoshitomo Chihara, Satoshi Maruyama, Hiroki Kuniyas. High matrix metalloproteinase-to-E-cadherin ratio measured by bicolor fluorescent in situ hybridization is associated with lymphangiogenesis and lymph node metastasis in prostate cancer. Urologic oncology. vol 30. issue 3. 2012-09-05. PMID:20843706. |
the colorimetric in situ hybridization (cish)-based matrix metalloproteinase (mmp)-to-e-cadherin (ecd) ratio (mer) has been revealed as an excellent marker for the disease stage in prostate cancer. |
2012-09-05 |
2023-08-12 |
Not clear |
| Lisa A Flynn, Angela R Blissett, Edward P Calomeni, Gunjan Agarwa. Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2. Journal of molecular biology. vol 395. issue 3. 2010-03-03. PMID:19900459. |
however, since soluble forms of ddr1 and ddr2 containing its ecd are known to naturally exist in the extracellular matrix, in this work we investigated if these soluble ddr ecds may have a functional role in modulating collagen fibrillogenesis. |
2010-03-03 |
2023-08-12 |
mouse |