All Relations between ds and basal ganglia

Publication Sentence Publish Date Extraction Date Species
Giuseppe Pasculli, Pierpaolo Busan, Eric S Jackson, Per A Alm, Danilo De Gregorio, Gerald A Maguire, Guy M Goodwin, Gabriella Gobbi, David Erritzoe, Robin L Carhart-Harri. Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective? Frontiers in human neuroscience. vol 18. 2024-07-04. PMID:38962146. the neural background of ds is likely to be heterogeneous, and some contribution from genetically determinants of metabolic deficiencies in the basal ganglia and speech-motor cortical regions are thought to play a role in appearance of ds symptoms, which possibly results in a cascade of events contributing to impairments in speech-motor execution. 2024-07-04 2024-07-10 Not clear
Eram Nahid, Saumya Gupta, Kshitij Prasad, Anish Kumar Saha, Mukti Prakash Meher, L P Meen. Diabetic striatopathy in an adult with ketotic hyperglycaemia. The National medical journal of India. vol 36. issue 4. 2024-05-01. PMID:38692636. ds is characterized by dyskinesias with basal ganglia hyperintensities on imaging. 2024-05-01 2024-05-04 Not clear
He Li, YiRan Cheng, Wei Tang, YiBin Hu, GeHui Jia, Tong Wu, KangFeng Wan. Cognitive decline as the main manifestation of diabetic striatal disease but without involuntary movements: a case report. BMC neurology. vol 23. issue 1. 2023-11-30. PMID:38036957. in this paper, we report a patient with ds who presented solely with subacute cognitive decline without involuntary movements, and cranial ct showed bilateral high density in the basal ganglia. 2023-11-30 2023-12-10 Not clear
A Arecco, S Ottaviani, M Boschetti, P Renzetti, L Marinell. Diabetic striatopathy: an updated overview of current knowledge and future perspectives. Journal of endocrinological investigation. 2023-08-14. PMID:37578646. diabetic striatopathy (ds) is a rare complication of poorly controlled diabetes mellitus (dm), characterized by hyperglycemia associated with chorea/ballism and characteristic reversible basal ganglia abnormalities on computed tomography (ct) and/or magnetic resonance imaging (mri). 2023-08-14 2023-08-16 Not clear
Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhur. Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35162984. extensive blood vessel damage in the basal ganglia and deposition of punctate ferritin heavy chain (fth) and hepcidin were found in the caudate and putamen within striosomes/matrix in both pd and ds brains. 2022-02-15 2023-08-13 human
Jerzy Wegiel, Michael Flory, Izabela Kuchna, Krzysztof Nowicki, Jarek Wegiel, Shuang Yong Ma, Nanbert Zhong, Teresa Wierzba Bobrowicz, Mony de Leon, Florence Lai, Wayne P Silverman, Thomas Wisniewsk. Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome. Acta neuropathologica communications. vol 10. issue 1. 2022-01-05. PMID:34983655. the aims of this study of 14 brain regions including the entorhinal cortex, hippocampus, basal ganglia, and cerebellum in 33 adults with ds 26-72 years of age were to identify the magnitude of brain region-specific developmental neuronal deficits contributing to intellectual deficits, to apply this baseline to identification of the topography and magnitude of neurodegeneration and neuronal and volume losses caused by eoad, and to establish age-based staging of the pattern of genetically driven neuropathology in ds. 2022-01-05 2023-08-13 human
Mihael Emilov Tsalta-Mladenov, Darina Kirilova Georgieva, Silva Peteva Andonov. Hyperglycemic hemichorea due to diabetic striatopathy: case-based review. Current medical research and opinion. 2021-12-07. PMID:34873977. ds predominantly leads to a unilateral reversible injury of the basal ganglia resulting in various movement disorders such as hemichorea and hemibalismus. 2021-12-07 2023-08-13 Not clear
Shigeki Kato, Kayo Nishizawa, Kazuto Kobayash. Thalamostriatal System Controls the Acquisition, Performance, and Flexibility of Learning Behavior. Frontiers in systems neuroscience. vol 15. 2021-11-05. PMID:34733142. the dorsal striatum (ds) is a key structure of the basal ganglia circuitry, which regulates various types of learning processes and flexible switching of behavior. 2021-11-05 2023-08-13 Not clear
Toru Imagi, Tomonaga Matsushita, Miyuki Matsushita, Yukako Yae, Takaoki Yokochi, Go Kawano, Yukihiro Akita, Keizo Ohbu, Toyojiro Matsuish. Brain stem infarction in a 6-year-old boy with Down syndrome. Brain & development. vol 41. issue 6. 2019-08-14. PMID:30857880. infarct locations in children with arterial ischemic stroke have primarily been reported to be lobar or in the basal ganglia, and those in patients with down syndrome (ds) and antiphospholipid syndrome (aps) are typically wide and multiple. 2019-08-14 2023-08-13 Not clear
Andrew Bowers, Lisa M Bowers, Daniel Hudock, Heather L Ramsdell-Hudoc. Phonological working memory in developmental stuttering: Potential insights from the neurobiology of language and cognition. Journal of fluency disorders. vol 58. 2019-05-07. PMID:30224087. to further address the role of attention and executive function in pwm and ds, we also review neurobiological models proposing that prefrontal cortex (pfc) and basal ganglia (bg) function to facilitate working memory under distracting conditions and neuroimaging evidence implicating the pfc and bg in stuttering. 2019-05-07 2023-08-13 Not clear
Samanta Rodrigues, Cristiane Salum, Tatiana L Ferreir. Dorsal striatum D1-expressing neurons are involved with sensorimotor gating on prepulse inhibition test. Journal of psychopharmacology (Oxford, England). vol 31. issue 4. 2018-01-04. PMID:28114835. these results point to an important role of ds, probably mediated by direct basal ganglia pathway, on modulation of sensorimotor gating, in accordance with clinical studies showing ppi deficits in schizophrenia, tourette syndrome, and compulsive disorders - pathologies related to basal ganglia dysfunctions. 2018-01-04 2023-08-13 rat
A S Karlsen, S Korbo, H B M Uylings, B Pakkenber. A stereological study of the mediodorsal thalamic nucleus in Down syndrome. Neuroscience. vol 279. 2015-07-08. PMID:25220902. the cortical structures of the same four ds brains were previously estimated to be half the normal size of controls with a reduction in cell numbers whereas the basal ganglia were unaffected. 2015-07-08 2023-08-13 Not clear
Anna Schou Karlsen, Bente Pakkenber. Total numbers of neurons and glial cells in cortex and basal ganglia of aged brains with Down syndrome--a stereological study. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 11. 2012-01-23. PMID:21427166. the total numbers of neurons and glial cells in the neocortex and basal ganglia in adults with down syndrome (ds) were estimated with design-based stereological methods, providing quantitative data on brains affected by delayed development and accelerated aging. 2012-01-23 2023-08-12 human
Anna Schou Karlsen, Bente Pakkenber. Total numbers of neurons and glial cells in cortex and basal ganglia of aged brains with Down syndrome--a stereological study. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 11. 2012-01-23. PMID:21427166. in contrast, the total number of neurons in the basal ganglia was the same in the 2 groups, whereas the number of oligodendrocytes in the basal ganglia was reduced by almost 50% in ds (405 × 10(6) vs. 816 × 10(6), 2p = 0.01). 2012-01-23 2023-08-12 human
Mara Dierssen, Yann Herault, Xavier Estivil. Aneuploidy: from a physiological mechanism of variance to Down syndrome. Physiological reviews. vol 89. issue 3. 2009-08-20. PMID:19584316. we present recent data on the role of genome-altering processes in the generation of diversity in ds neural phenotypes focusing on the impact of trisomy on brain structure and mental retardation and on biological pathways and cell types in target brain regions (including prefrontal cortex, hippocampus, cerebellum, and basal ganglia). 2009-08-20 2023-08-12 mouse
M El-Ruby, N A Hemly, M S Zak. Maternal balanced translocation (4;21) leading to an offspring with partial duplication of 4q and 21q without phenotypic manifestations of Down syndrome. Genetic counseling (Geneva, Switzerland). vol 18. issue 2. 2007-10-16. PMID:17710874. in spite of detection of most of the 3 copies of chromosome 21, specific features of down syndrome (ds) were lacked in this patient, except for notable bilateral symmetrical calcification of basal ganglia. 2007-10-16 2023-08-12 Not clear
M El-Ruby, N A Hemly, M S Zak. Maternal balanced translocation (4;21) leading to an offspring with partial duplication of 4q and 21q without phenotypic manifestations of Down syndrome. Genetic counseling (Geneva, Switzerland). vol 18. issue 2. 2007-10-16. PMID:17710874. nevertheless, presence of basal ganglia calcification in this patient may point out to a more proximal region contributing in its development in ds, or that genes outside the critical region may influence or control manifestations of ds features. 2007-10-16 2023-08-12 Not clear
R Seidl, S T Kaehler, H Prast, N Singewald, N Cairns, M Gratzer, G Lube. Serotonin (5-HT) in brains of adult patients with Down syndrome. Journal of neural transmission. Supplementum. vol 57. 2000-04-12. PMID:10666678. the results of this study confirm and extend putatively specific 5-ht dysfunction in basal ganglia (caudate nucleus) of adult ds, which is not present in ad. 2000-04-12 2023-08-12 Not clear
E H Aylward, Q Li, Q R Habbak, A Warren, M B Pulsifer, P E Barta, M Jerram, G Pearlso. Basal ganglia volume in adults with Down syndrome. Psychiatry research. vol 74. issue 2. 1997-08-28. PMID:9204510. results suggest that volume reductions of the basal ganglia are not a salient feature of aging or of the dementia associated with ds. 1997-08-28 2023-08-12 human
E H Aylward, Q Li, Q R Habbak, A Warren, M B Pulsifer, P E Barta, M Jerram, G Pearlso. Basal ganglia volume in adults with Down syndrome. Psychiatry research. vol 74. issue 2. 1997-08-28. PMID:9204510. although there were some significant correlations between basal ganglia volumes and age, neuropsychological test performance, and dementia status in the ds subjects, these associations appeared to be a reflection of neurodevelopmental or atrophic reductions in overall brain volume rather than a reflection of specific basal ganglia abnormality. 1997-08-28 2023-08-12 human