| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael J Christensen, Trevor J Huff, Austin M Pickrell, Samuel N Roger. Simultaneously occurring diabetic striatopathy and osmotic demyelination syndrome: A rare case report. The neuroradiology journal. 2025-03-17. PMID:40096849. |
specifically, the patient demonstrated unilateral basal ganglia hyperdensity on ct, indicative of ds, alongside central pontine diffusion restriction and t2/flair hyperintensity, consistent with ods. |
2025-03-17 |
2025-03-20 |
Not clear |
| Yaning Chen, Chunliu Wu, Ming Ren, Qingjun Wang, Zhiwei Wang, Yimo Zhang, Yingxin Y. Clinical and neuroimaging characteristics of diabetic striatopathy: a case series report. Frontiers in endocrinology. vol 15. 2024-12-25. PMID:39720255. |
diabetic striatopathy (ds) is a rare disorder characterized by clinical manifestations of hemichorea, non-ketotic hyperglycemia, and high signal on t1-weighted mri or high density on ct scan in basal ganglia, typically associated with poor glycemic control. |
2024-12-25 |
2024-12-27 |
Not clear |
| Paula A Calvo, Raquel Flore. Diabetic Striatopathy: A Case Report of Two Distinct Presentations in Elderly Patients. Cureus. vol 16. issue 10. 2024-11-26. PMID:39588441. |
the diagnosis of diabetic striatopathy (ds) is based on the presence of a triad characterized by hyperglycemia, hemiballismus/chorea, and hypersignal of the basal ganglia on t1-weighted mri. |
2024-11-26 |
2024-11-28 |
Not clear |
| Marco Emili, Fiorenza Stagni, Maria Paola Bonasoni, Sandra Guidi, Renata Bartesagh. Cellularity Defects Are Not Ubiquitous in the Brains of Fetuses With Down Syndrome. Developmental neurobiology. 2024-09-30. PMID:39344402. |
the hypocellularity found in the basal ganglia, which are critically implicated in the control of movement, suggests that such alterations may contribute to the motor abnormalities of ds. |
2024-09-30 |
2024-10-02 |
Not clear |
| Marco Emili, Fiorenza Stagni, Maria Paola Bonasoni, Sandra Guidi, Renata Bartesagh. Cellularity Defects Are Not Ubiquitous in the Brains of Fetuses With Down Syndrome. Developmental neurobiology. 2024-09-30. PMID:39344402. |
in the current study, we have examined the basal ganglia, the insular cortex (ins), and the cingulate cortex (ccx) of fetuses with ds and age-matched controls (18-22 weeks of gestation), to establish whether cellularity defects involve regions that are not primarily involved in explicit memory. |
2024-09-30 |
2024-10-02 |
Not clear |
| Giuseppe Pasculli, Pierpaolo Busan, Eric S Jackson, Per A Alm, Danilo De Gregorio, Gerald A Maguire, Guy M Goodwin, Gabriella Gobbi, David Erritzoe, Robin L Carhart-Harri. Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective? Frontiers in human neuroscience. vol 18. 2024-07-04. PMID:38962146. |
the neural background of ds is likely to be heterogeneous, and some contribution from genetically determinants of metabolic deficiencies in the basal ganglia and speech-motor cortical regions are thought to play a role in appearance of ds symptoms, which possibly results in a cascade of events contributing to impairments in speech-motor execution. |
2024-07-04 |
2024-07-10 |
Not clear |
| Eram Nahid, Saumya Gupta, Kshitij Prasad, Anish Kumar Saha, Mukti Prakash Meher, L P Meen. Diabetic striatopathy in an adult with ketotic hyperglycaemia. The National medical journal of India. vol 36. issue 4. 2024-05-01. PMID:38692636. |
ds is characterized by dyskinesias with basal ganglia hyperintensities on imaging. |
2024-05-01 |
2024-05-04 |
Not clear |
| He Li, YiRan Cheng, Wei Tang, YiBin Hu, GeHui Jia, Tong Wu, KangFeng Wan. Cognitive decline as the main manifestation of diabetic striatal disease but without involuntary movements: a case report. BMC neurology. vol 23. issue 1. 2023-11-30. PMID:38036957. |
in this paper, we report a patient with ds who presented solely with subacute cognitive decline without involuntary movements, and cranial ct showed bilateral high density in the basal ganglia. |
2023-11-30 |
2023-12-10 |
Not clear |
| A Arecco, S Ottaviani, M Boschetti, P Renzetti, L Marinell. Diabetic striatopathy: an updated overview of current knowledge and future perspectives. Journal of endocrinological investigation. 2023-08-14. PMID:37578646. |
diabetic striatopathy (ds) is a rare complication of poorly controlled diabetes mellitus (dm), characterized by hyperglycemia associated with chorea/ballism and characteristic reversible basal ganglia abnormalities on computed tomography (ct) and/or magnetic resonance imaging (mri). |
2023-08-14 |
2023-08-16 |
Not clear |
| Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhur. Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35162984. |
extensive blood vessel damage in the basal ganglia and deposition of punctate ferritin heavy chain (fth) and hepcidin were found in the caudate and putamen within striosomes/matrix in both pd and ds brains. |
2022-02-15 |
2023-08-13 |
human |
| Jerzy Wegiel, Michael Flory, Izabela Kuchna, Krzysztof Nowicki, Jarek Wegiel, Shuang Yong Ma, Nanbert Zhong, Teresa Wierzba Bobrowicz, Mony de Leon, Florence Lai, Wayne P Silverman, Thomas Wisniewsk. Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome. Acta neuropathologica communications. vol 10. issue 1. 2022-01-05. PMID:34983655. |
the aims of this study of 14 brain regions including the entorhinal cortex, hippocampus, basal ganglia, and cerebellum in 33 adults with ds 26-72 years of age were to identify the magnitude of brain region-specific developmental neuronal deficits contributing to intellectual deficits, to apply this baseline to identification of the topography and magnitude of neurodegeneration and neuronal and volume losses caused by eoad, and to establish age-based staging of the pattern of genetically driven neuropathology in ds. |
2022-01-05 |
2023-08-13 |
human |
| Mihael Emilov Tsalta-Mladenov, Darina Kirilova Georgieva, Silva Peteva Andonov. Hyperglycemic hemichorea due to diabetic striatopathy: case-based review. Current medical research and opinion. 2021-12-07. PMID:34873977. |
ds predominantly leads to a unilateral reversible injury of the basal ganglia resulting in various movement disorders such as hemichorea and hemibalismus. |
2021-12-07 |
2023-08-13 |
Not clear |
| Shigeki Kato, Kayo Nishizawa, Kazuto Kobayash. Thalamostriatal System Controls the Acquisition, Performance, and Flexibility of Learning Behavior. Frontiers in systems neuroscience. vol 15. 2021-11-05. PMID:34733142. |
the dorsal striatum (ds) is a key structure of the basal ganglia circuitry, which regulates various types of learning processes and flexible switching of behavior. |
2021-11-05 |
2023-08-13 |
Not clear |
| Toru Imagi, Tomonaga Matsushita, Miyuki Matsushita, Yukako Yae, Takaoki Yokochi, Go Kawano, Yukihiro Akita, Keizo Ohbu, Toyojiro Matsuish. Brain stem infarction in a 6-year-old boy with Down syndrome. Brain & development. vol 41. issue 6. 2019-08-14. PMID:30857880. |
infarct locations in children with arterial ischemic stroke have primarily been reported to be lobar or in the basal ganglia, and those in patients with down syndrome (ds) and antiphospholipid syndrome (aps) are typically wide and multiple. |
2019-08-14 |
2023-08-13 |
Not clear |
| Andrew Bowers, Lisa M Bowers, Daniel Hudock, Heather L Ramsdell-Hudoc. Phonological working memory in developmental stuttering: Potential insights from the neurobiology of language and cognition. Journal of fluency disorders. vol 58. 2019-05-07. PMID:30224087. |
to further address the role of attention and executive function in pwm and ds, we also review neurobiological models proposing that prefrontal cortex (pfc) and basal ganglia (bg) function to facilitate working memory under distracting conditions and neuroimaging evidence implicating the pfc and bg in stuttering. |
2019-05-07 |
2023-08-13 |
Not clear |
| Samanta Rodrigues, Cristiane Salum, Tatiana L Ferreir. Dorsal striatum D1-expressing neurons are involved with sensorimotor gating on prepulse inhibition test. Journal of psychopharmacology (Oxford, England). vol 31. issue 4. 2018-01-04. PMID:28114835. |
these results point to an important role of ds, probably mediated by direct basal ganglia pathway, on modulation of sensorimotor gating, in accordance with clinical studies showing ppi deficits in schizophrenia, tourette syndrome, and compulsive disorders - pathologies related to basal ganglia dysfunctions. |
2018-01-04 |
2023-08-13 |
rat |
| A S Karlsen, S Korbo, H B M Uylings, B Pakkenber. A stereological study of the mediodorsal thalamic nucleus in Down syndrome. Neuroscience. vol 279. 2015-07-08. PMID:25220902. |
the cortical structures of the same four ds brains were previously estimated to be half the normal size of controls with a reduction in cell numbers whereas the basal ganglia were unaffected. |
2015-07-08 |
2023-08-13 |
Not clear |
| Anna Schou Karlsen, Bente Pakkenber. Total numbers of neurons and glial cells in cortex and basal ganglia of aged brains with Down syndrome--a stereological study. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 11. 2012-01-23. PMID:21427166. |
the total numbers of neurons and glial cells in the neocortex and basal ganglia in adults with down syndrome (ds) were estimated with design-based stereological methods, providing quantitative data on brains affected by delayed development and accelerated aging. |
2012-01-23 |
2023-08-12 |
human |
| Anna Schou Karlsen, Bente Pakkenber. Total numbers of neurons and glial cells in cortex and basal ganglia of aged brains with Down syndrome--a stereological study. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 11. 2012-01-23. PMID:21427166. |
in contrast, the total number of neurons in the basal ganglia was the same in the 2 groups, whereas the number of oligodendrocytes in the basal ganglia was reduced by almost 50% in ds (405 × 10(6) vs. 816 × 10(6), 2p = 0.01). |
2012-01-23 |
2023-08-12 |
human |
| Mara Dierssen, Yann Herault, Xavier Estivil. Aneuploidy: from a physiological mechanism of variance to Down syndrome. Physiological reviews. vol 89. issue 3. 2009-08-20. PMID:19584316. |
we present recent data on the role of genome-altering processes in the generation of diversity in ds neural phenotypes focusing on the impact of trisomy on brain structure and mental retardation and on biological pathways and cell types in target brain regions (including prefrontal cortex, hippocampus, cerebellum, and basal ganglia). |
2009-08-20 |
2023-08-12 |
mouse |