| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Megan Caldwell, Vanessa Ayo-Jibunoh, Josue Criollo Mendoza, Katherine R Brimblecombe, Lauren M Reynolds, Xin Yan Zhu Jiang, Colin Alarcon, Elizabeth Fiore, Jacquelyn N Tomaio, Greg R Phillips, Susana Mingote, Cecilia Flores, Patrizia Casaccia, Jia Liu, Stephanie J Cragg, Dan P McCloskey, Leora Yetnikof. Axo-glial interactions between midbrain dopamine neurons and oligodendrocyte lineage cells in the anterior corpus callosum. Brain structure & function. 2023-09-05. PMID:37668732. |
using rnascope, we further demonstrate that\xe2\x80\x89~\xe2\x80\x8940% of olig2\xe2\x80\x89+\xe2\x80\x89/pdfgra\xe2\x80\x89+\xe2\x80\x89cells and\xe2\x80\x89~\xe2\x80\x8920% of olig2\xe2\x80\x89+\xe2\x80\x89/pdgfra- cells in the anterior corpus callosum express drd1 and drd2 transcripts. |
2023-09-05 |
2023-09-07 |
mouse |
| Navina Suresh, Suvarna Jyothi Kantipudi, Deepika Ramu, Suresh Kumar Muniratnam, Vettriselvi Venkatesa. Association between opioid and dopamine receptor gene polymorphisms OPRM1rs1799971, DAT VNTR9-10 repeat allele, DRD1 rs4532 and DRD2 rs1799732 and alcohol dependence: an ethnicity oriented meta-analysis. Pharmacogenetics and genomics. 2023-07-19. PMID:37466123. |
we carried out a meta-analysis of four opioid and dopamine candidate gene polymorphisms having conflicting results in prior literature, namely oprm1 rs1799971, dat vntr9-10 repeat, drd1 rs4532 and drd2 rs1799732, to clarify their association with alcohol dependence and further stratified results by ethnicity to analyze possible ethnicity-mediated effects. |
2023-07-19 |
2023-08-14 |
Not clear |
| Ewa Ferensztajn-Rochowiak, Monika Dmitrzak-W\\xc4\\x99glarz, Aleksandra Szczepankiewicz, Maria Skibi\\xc5\\x84ska, Sebastian Kliwicki, Agnieszka Permoda-Pachuta, Aleksandra Suwalska, Piotr Czerski, Joanna Pawlak, Joanna Hause. Studies on candidate genes for lithium prophylaxis performed at the Poznan University of Medical Sciences. Psychiatria polska. vol 56. issue 5. 2023-04-19. PMID:37074853. |
the associations with lithium prophylactic efficacy were found for the polymorphisms in 5htt, acp1, arntl, bdnf, comt, drd1, fkbp5, fyn, glcc, nr3c1, and tim, genes, but not those in 5ht2a, 5ht2c, drd2, drd3, drd4, grin2b, gsk-3\xce\xb2, mmp-9, and ntrk2 genes. |
2023-04-19 |
2023-08-14 |
Not clear |
| Micha\\xc5\\x82 Szulc, Rados\\xc5\\x82aw Kujawski, Amanda Pacholak, Marta Poprawska, Kamila Czora-Poczwardowska, Bogna Geppert, Przemys\\xc5\\x82aw \\xc5\\x81 Miko\\xc5\\x82ajcza. Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats. Nutrients. vol 15. issue 7. 2023-04-13. PMID:37049542. |
in the prefrontal cortex, hippocampus, and striatum, the cannabinoid (cb1r and cb2r) and dopaminergic (drd1, drd2, drd4, drd5) receptors' mrna level changes were analyzed using the quantitative rt-pcr method. |
2023-04-13 |
2023-08-14 |
rat |
| Micha\\xc5\\x82 Szulc, Rados\\xc5\\x82aw Kujawski, Amanda Pacholak, Marta Poprawska, Kamila Czora-Poczwardowska, Bogna Geppert, Przemys\\xc5\\x82aw \\xc5\\x81 Miko\\xc5\\x82ajcza. Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats. Nutrients. vol 15. issue 7. 2023-04-13. PMID:37049542. |
for cb1r, drd1, and drd2 mrnas, the cbd + ethanol interaction produced opposite effects than for cb2r ones. |
2023-04-13 |
2023-08-14 |
rat |
| Darya Bazovkina, Nina B Illarionova, Elizabeth A Kulikova, Ekaterina Yu Bazhenova, Nadezhda A Sinyakova, Nikita V Khotskin, Sergey Nikitin, Vasily S Lankin, Elena E Terenina, Oleg V Trapezov, Aleksandr V Kuliko. Studying the brain monoaminergic systems and neurotrophic factors in minipigs with high and low tolerance to the presence of human. Brain, behavior and evolution. 2023-03-13. PMID:36913918. |
however, the expression of genes regulating a dopaminergic system (comt, drd1 and drd2) in ht and lt animal groups varied depending on brain structure. |
2023-03-13 |
2023-08-14 |
human |
| Hae-Yeon Park, Hyun-Mi Oh, Tae-Woo Kim, Youngkook Kim, Geun-Young Park, Hyemi Hwang, Sun I. Single Nucleotide Polymorphisms May Increase the Risk of Aspiration Pneumonia in Post-Stroke Patients with Dysphagia. Current issues in molecular biology. vol 44. issue 8. 2023-03-08. PMID:36005151. |
genotyping was performed for catechol-o-methyltransferase (rs4680, rs165599), dopamine receptors (drd1; rs4532, drd2; rs1800497, drd3; rs6280), brain-derived neurotrophic factor (rs6265), apolipoprotein e (rs429358, rs7412), and the interleukin-1 receptor antagonist gene (rs4251961). |
2023-03-08 |
2023-08-16 |
human |
| Ayako Maegawa, Koshi Murata, Kazuki Kuroda, Shigeharu Fujieda, Yugo Fukazaw. Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice. Frontiers in neural circuits. vol 16. 2022-08-08. PMID:35937204. |
neuronal subtypes of the ot can be distinguished by their expression of the dopamine receptors d1 (drd1) and d2 (drd2). |
2022-08-08 |
2023-08-14 |
mouse |
| Mengwei Wu, Yeqing Chen, Zui Shen, Yichen Zhu, Siqi Xiao, Xixiao Zhu, Zemin Wu, Jinggen Liu, Chi Xu, Pingan Yao, Weiwei Xu, Yi Liang, Boyi Liu, Junying Du, Xiaofen He, Boyu Liu, Xiaoming Jin, Jianqiao Fang, Xiaomei Sha. Electroacupuncture Alleviates Anxiety-Like Behaviors Induced by Chronic Neuropathic Pain via Regulating Different Dopamine Receptors of the Basolateral Amygdala. Molecular neurobiology. 2022-06-13. PMID:35696012. |
dopamine receptor d1 (drd1) and dopamine receptor d2 (drd2) in the basolateral amygdala (bla) have been implicated in mediating anxiety-related behaviors, but their potential roles in the bla in neuropathic pain-induced anxiety have not been examined. |
2022-06-13 |
2023-08-14 |
mouse |
| Mengwei Wu, Yeqing Chen, Zui Shen, Yichen Zhu, Siqi Xiao, Xixiao Zhu, Zemin Wu, Jinggen Liu, Chi Xu, Pingan Yao, Weiwei Xu, Yi Liang, Boyi Liu, Junying Du, Xiaofen He, Boyu Liu, Xiaoming Jin, Jianqiao Fang, Xiaomei Sha. Electroacupuncture Alleviates Anxiety-Like Behaviors Induced by Chronic Neuropathic Pain via Regulating Different Dopamine Receptors of the Basolateral Amygdala. Molecular neurobiology. 2022-06-13. PMID:35696012. |
electroacupuncture (ea) is commonly used to treat chronic pain and emotional disorders, but it is still unclear whether ea plays a role in analgesia and anxiety relief through drd1 and drd2 in the bla. |
2022-06-13 |
2023-08-14 |
mouse |
| Mengwei Wu, Yeqing Chen, Zui Shen, Yichen Zhu, Siqi Xiao, Xixiao Zhu, Zemin Wu, Jinggen Liu, Chi Xu, Pingan Yao, Weiwei Xu, Yi Liang, Boyi Liu, Junying Du, Xiaofen He, Boyu Liu, Xiaoming Jin, Jianqiao Fang, Xiaomei Sha. Electroacupuncture Alleviates Anxiety-Like Behaviors Induced by Chronic Neuropathic Pain via Regulating Different Dopamine Receptors of the Basolateral Amygdala. Molecular neurobiology. 2022-06-13. PMID:35696012. |
to further demonstrate the role of drd1 and drd2 in the bla in spared nerve injury (sni) model-induced anxiety-like behaviors, we injected the drd1 agonist skf38393 or the drd2 antagonist sulpiride into the bla. |
2022-06-13 |
2023-08-14 |
mouse |
| Stephanie Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Joanna Canagarajah, Kaitlyn Runner, Emily Nickoloff-Bybel, Peter J Gaskil. Dopamine-driven Increase in IL-1\\xce\\xb2 in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556752. |
studies indicate that d1-like dopamine receptors (drd1, drd5) mediate inflammatory activity while d2-like dopamine receptors (drd2, drd3, and drd4) mediate anti-inflammatory activity, and we have shown that human macrophages and microglia have higher expression of d1-like receptors. |
2022-05-13 |
2023-08-13 |
human |
| Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-05-02. PMID:35501380. |
furthermore, in the activity-based anorexia (aba) paradigm, which is a mouse model mimicking some clinical features of human anorexia nervosa (an), we observed a drd2 to drd1 shift of da neurotransmission on 5-ht |
2022-05-02 |
2023-08-13 |
mouse |
| Fatima Zahra Rami, Thong Ba Nguyen, Young-Eun Oh, Maryam Karamikheirabad, Thi-Hung Le, Young-Chul Chun. Risperidone Induced DNA Methylation Changes in Dopamine Receptor and Stathmin Genes in Mice Exposed to Social Defeat Stress. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 20. issue 2. 2022-04-25. PMID:35466108. |
this study investigated dna methylation and mrna expression levels of dopamine d2 and d1 receptor (drd2 and drd1, respectively), nuclear receptor subfamily 3, group c, member 1 (nr3c1) and stathmin 1 (stmn1) in brain regions of mice exposed to social defeat stress (sds) and effects of risperidone on altered methylation and mrna expression levels induced by sds. |
2022-04-25 |
2023-08-13 |
mouse |
| Hyunbin Kim, Min-Ho Nam, Sohyeon Jeong, Hyowon Lee, Soo-Jin Oh, Jeongjin Kim, Nakwon Choi, Jihye Seon. Visualization of differential GPCR crosstalk in DRD1-DRD2 heterodimer upon different dopamine levels. Progress in neurobiology. 2022-04-01. PMID:35364139. |
these dopamine signals can be differentially translated by dopamine receptor type 1 and type 2, drd1 and drd2, which are g protein-coupled receptors (gpcrs). |
2022-04-01 |
2023-08-13 |
Not clear |
| Hyunbin Kim, Min-Ho Nam, Sohyeon Jeong, Hyowon Lee, Soo-Jin Oh, Jeongjin Kim, Nakwon Choi, Jihye Seon. Visualization of differential GPCR crosstalk in DRD1-DRD2 heterodimer upon different dopamine levels. Progress in neurobiology. 2022-04-01. PMID:35364139. |
in response to dopamine, drd1 and drd2 are known to mediate opposite functions on camp production via gs and gi protein signaling. |
2022-04-01 |
2023-08-13 |
Not clear |
| Hyunbin Kim, Min-Ho Nam, Sohyeon Jeong, Hyowon Lee, Soo-Jin Oh, Jeongjin Kim, Nakwon Choi, Jihye Seon. Visualization of differential GPCR crosstalk in DRD1-DRD2 heterodimer upon different dopamine levels. Progress in neurobiology. 2022-04-01. PMID:35364139. |
utilizing these powerful tools, we surprisingly discover differential crosstalk in the drd1-drd2 heterodimers upon different dopamine (da) levels: drd1 activation is selectively inhibited at micromolar da levels, while drd2 is inhibited only by nanomolar da concentration, implying a novel function of the drd1-drd2 heterodimer upon different da levels. |
2022-04-01 |
2023-08-13 |
Not clear |
| Vanessa Feistauer, Joana Fisch, Carolina Kalkmann da Silva Oliveira, M\\xc3\\xa1rcia Giovenardi, Silvana Almeid. Restriction and hyperlipidic diets during pregnancy, lactation and adult life modified the expression of dopaminergic system related genes both in female mice and their adult offspring. Brain research bulletin. vol 162. 2021-09-29. PMID:32619693. |
in dams' vta, both diets upregulated the expression of th, slc6a3/dat1, drd1 and drd2 genes. |
2021-09-29 |
2023-08-13 |
mouse |
| T C Peixoto, E G Moura, P N Soares, V S T Rodrigues, S Claudio-Neto, E Oliveira, A C Manh\\xc3\\xa3es, P C Lisbo. Nicotine exposure during lactation causes disruption of hedonic eating behavior and alters dopaminergic system in adult female rats. Appetite. vol 160. 2021-06-24. PMID:33453337. |
nic females showed hyperphagia, preference for a high-sucrose diet, increased anxiety-like behavior, lower tyrosine hydroxylase (th), lower dopamine transporter and higher dopamine receptor (drd2) in nac; lower drd1 in prefrontal cortex and lower th in dorsal striatum (ds). |
2021-06-24 |
2023-08-13 |
rat |
| Yao Fan, Rongrong Zha, Tomohiko Sano, Xinyu Zhao, Shengzhi Liu, Mark D Woollam, Di Wu, Xun Sun, Kexin Li, Motoki Egi, Fangjia Li, Kazumasa Minami, Amanda P Siegel, Takashi Horiuchi, Jing Liu, Mangilal Agarwal, Akihiro Sudo, Harikrishna Nakshatri, Bai-Yan Li, Hiroki Yokot. Mechanical tibial loading remotely suppresses brain tumors by dopamine-mediated downregulation of CCN4. Bone research. vol 9. issue 1. 2021-06-09. PMID:34031366. |
dopamine and fp exerted antitumor effects through the dopamine receptors drd1 and drd2, respectively. |
2021-06-09 |
2023-08-13 |
mouse |