| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Macarena González-Portilla, Sandra Montagud-Romero, Susana Mellado, Fernando Rodríguez de Fonseca, María Pascual, Marta Rodríguez-Aria. Region-Specific Gene Expression Changes Associated with Oleoylethanolamide-Induced Attenuation of Alcohol Self-Administration. International journal of molecular sciences. vol 25. issue 16. 2024-08-29. PMID:39201687. |
in addition, we measured gene expression changes in the striatum and hippocampus of relevant receptors for alcohol consumption (drd1, drd2, cnr1, oprm) as well as immune-related proteins (il-6, il-1β, tlr4) and the brain-derived neurotrophic factor (bdnf). |
2024-08-29 |
2024-09-04 |
Not clear |
| P D Pravikova, M A Arssan, E A Zalivina, E M Kondaurova, E A Kulikova, I I Belokopytova, V S Naumenk. Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6 J). Vavilovskii zhurnal genetiki i selektsii. vol 28. issue 4. 2024-07-19. PMID:39027124. |
in this study, we investigated the expression of key dopamine receptors (drd1, drd2), brain-derived neurotrophic factor (bdnf), its receptors (ntrkb2, ngfr) and the transcription factor creb1 that mediates bdnf action, as well as cerebral dopamine neurotrophic factor (cdnf) during the critical periods of embryogenesis (e14 and e18) and postnatal development (p14, p28, p60) in the hippocampus and frontal cortex of btbr mice with autism-like behavior compared to the neurotypical c57bl/6 j strain. |
2024-07-19 |
2024-07-21 |
mouse |
| P D Pravikova, M A Arssan, E A Zalivina, E M Kondaurova, E A Kulikova, I I Belokopytova, V S Naumenk. Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6 J). Vavilovskii zhurnal genetiki i selektsii. vol 28. issue 4. 2024-07-19. PMID:39027124. |
a decrease in the expression of cdnf, bdnf and its receptor ntrkb2, as well as dopamine receptors (drd1, drd2) was detected in btbr mice in the postnatal period of ontogenesis mainly in the frontal cortex, while in the hippocampus of mature mice (p60), only a decrease in the drd2 mrna level was revealed. |
2024-07-19 |
2024-07-21 |
mouse |
| Yujie Huang, Ruoting Qing, Yu Yang, Ming Li, Jun Ga. Sex and Age Differences in Ontogeny of Alloparenting: A Relation to Forebrain DRD1, DRD2, and HTR2A mRNA Expression? Developmental psychobiology. vol 66. issue 6. 2024-07-08. PMID:38973227. |
sex and age differences in ontogeny of alloparenting: a relation to forebrain drd1, drd2, and htr2a mrna expression? |
2024-07-08 |
2024-07-11 |
rat |
| Stephanie M Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C M Schlachetzki, Howard S Fox, Peter J Gaskil. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915663. |
however, the exact pathways by which dopamine drives myeloid inflammation are not well defined, and studies in both rodent and human systems indicate that dopamine can impact the production of inflammatory mediators through both d1-like dopamine receptors (drd1, drd5) and d2-like dopamine receptors (drd2, drd3, and drd4). |
2024-06-25 |
2024-06-27 |
human |
| Stephanie M Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C M Schlachetzki, Howard S Fox, Peter J Gaskil. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915663. |
our data in primary human monocyte-derived macrophages (hmdm) indicate that drd1 expression is necessary for dopamine-mediated increases in il-1β, and that changes in the expression of drd2 and other dopamine receptors can alter the magnitude of the dopamine-mediated increase in il-1β. |
2024-06-25 |
2024-06-27 |
human |
| Sanae Inokuchi-Sakata, Ryo Narita, Yukari Takahashi, Yozo Ishiuji, Akihiko Asahina, Fusao Kat. Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice - a model-free multivariate analysis. Molecular brain. vol 17. issue 1. 2024-05-24. PMID:38783364. |
in the brains of mice exhibiting scratching behaviors, we analyzed the expression of the c-fos gene (fos) as a readout of an immediate activation of neurons during itch/scratch and dopamine receptors (drd1 and drd2) using multiplex single-molecule fluorescence in situ hybridization (rnascope) in the nac and surrounding structures. |
2024-05-24 |
2024-05-27 |
mouse |
| Megan Caldwell, Josue Criollo Mendoza, Xin Yan Zhu Jiang, Colin Alarcon, Vanessa Ayo-Jibunoh, Shelby Louis, Daniel Maronna, Rania Darwish, Jaquelyn Tomaio, Susana Mingote, Leora Yetnikof. Reorganization of dopamine circuitry in the anterior corpus callosum between early adolescence and adulthood in the mouse. The European journal of neuroscience. vol 59. issue 10. 2024-05-21. PMID:38720367. |
we further demonstrate with rnascope that, as in the adult, drd1 and drd2 transcripts are expressed at higher levels in oligodendrocyte precursor cells (opcs) and decline as these cells differentiate into oligodendrocytes. |
2024-05-21 |
2024-05-27 |
mouse |
| Hanfei Sun, Yi Feng, Shaoqin Tu, Jianwu Zhou, Yuxuan Wang, Jiaming Wei, Sai Zhang, Yuluan Hou, Yiting Shao, Hong Ai, Zheng Che. Dopamine promotes osteogenic differentiation of PDLSCs by activating DRD1 and DRD2 during orthodontic tooth movement via ERK1/2 signaling pathway. Regenerative therapy. vol 27. 2024-04-15. PMID:38617443. |
dopamine promotes osteogenic differentiation of pdlscs by activating drd1 and drd2 during orthodontic tooth movement via erk1/2 signaling pathway. |
2024-04-15 |
2024-04-17 |
Not clear |
| Hong-Hua Li, Xi-Fei Wang, Bing Wang, Fei-Yong Ji. Vitamin D3 improves iminodipropionitrile-induced tic-like behavior in rats through regulation of GDNF/c-Ret signaling activity. European child & adolescent psychiatry. 2024-02-24. PMID:38396228. |
all groups were tested for behavior, serum and striatal 25(oh)d and dopamine (da), mrna expressions of vitamin d receptor (vdr), glial cell line-derived neurotrophic factor (gdnf), protooncogene tyrosine-protein kinase receptor ret (c-ret), and da d1 (drd1) and d2 (drd2) receptor genes in the striatum. |
2024-02-24 |
2024-02-26 |
rat |
| C Medina-Saldivar, G V E Pardo, L F Pacheco-Otalor. Effect of MCH1, a fatty-acid amide hydrolase inhibitor, on the depressive-like behavior and gene expression of endocannabinoid and dopaminergic-signaling system in the mouse nucleus accumbens. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-02-21. PMID:38381881. |
the present study aimed to evaluate the effect of the in vivo administration of mch1 (3, 10, and 30 mg/kg, ip) in 2-month-old balb/c male mice (n=97) on forced swimming test (fst), light-dark box (ldb), and open field test (oft) and on early gene expression changes 2 h after drug injection related to the endocannabinoid system (cnr1 and faah) and dopaminergic signaling (drd1 and drd2) in the nac core. |
2024-02-21 |
2024-02-24 |
mouse |
| Heliana de Barros Fernandes, Bruna da Silva Oliveira, Caroline Amaral Machado, Brener Cunha Carvalho, Eliana Cristina de Brito Toscano, Maria Carolina M da Silva, Érica Leandro Marciano Vieira, Antônio Carlos Pinheiro de Oliveira, Antônio Lúcio Teixeira, Aline Silva de Miranda, Aristóbolo Mendes da Silv. Behavioral, neurochemical and neuroimmune features of RasGEF1b deficient mice. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-04. PMID:38048936. |
a down-regulation of mrna of dopamine receptor (drd1, drd2, drd4 and drd5) and serotonin receptor genes (5htr1a, 5htr1b and 5htr1d) was observed in hippocampus of rasgef1b-cko mice. |
2023-12-04 |
2023-12-10 |
mouse |
| Heliana de Barros Fernandes, Bruna da Silva Oliveira, Caroline Amaral Machado, Brener Cunha Carvalho, Eliana Cristina de Brito Toscano, Maria Carolina M da Silva, Érica Leandro Marciano Vieira, Antônio Carlos Pinheiro de Oliveira, Antônio Lúcio Teixeira, Aline Silva de Miranda, Aristóbolo Mendes da Silv. Behavioral, neurochemical and neuroimmune features of RasGEF1b deficient mice. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-04. PMID:38048936. |
these mice also had reduction of drd1 and drd2 in prefrontal cortex and 5htr1d in striatum. |
2023-12-04 |
2023-12-10 |
mouse |
| Maurilyn Ayon-Olivas, Daniel Wolf, Thomas Andreska, Noelia Granado, Patrick Lüningschrör, Chi Wang Ip, Rosario Moratalla, Michael Sendtne. Dopaminergic Input Regulates the Sensitivity of Indirect Pathway Striatal Spiny Neurons to Brain-Derived Neurotrophic Factor. Biology. vol 12. issue 10. 2023-10-27. PMID:37887070. |
dopamine receptor d1 (drd1) stimulation is a crucial step in the formation of long-term potentiation (ltp), whereas dopamine receptor d2 (drd2) stimulation is needed for the formation of long-term depression (ltd) in striatal spiny projection neurons (spns). |
2023-10-27 |
2023-11-08 |
Not clear |
| Maurilyn Ayon-Olivas, Daniel Wolf, Thomas Andreska, Noelia Granado, Patrick Lüningschrör, Chi Wang Ip, Rosario Moratalla, Michael Sendtne. Dopaminergic Input Regulates the Sensitivity of Indirect Pathway Striatal Spiny Neurons to Brain-Derived Neurotrophic Factor. Biology. vol 12. issue 10. 2023-10-27. PMID:37887070. |
this provides an explanation for the opposing synaptic plasticity changes observed upon drd1 or drd2 stimulation. |
2023-10-27 |
2023-11-08 |
Not clear |
| Megan Caldwell, Vanessa Ayo-Jibunoh, Josue Criollo Mendoza, Katherine R Brimblecombe, Lauren M Reynolds, Xin Yan Zhu Jiang, Colin Alarcon, Elizabeth Fiore, Jacquelyn N Tomaio, Greg R Phillips, Susana Mingote, Cecilia Flores, Patrizia Casaccia, Jia Liu, Stephanie J Cragg, Dan P McCloskey, Leora Yetnikof. Axo-glial interactions between midbrain dopamine neurons and oligodendrocyte lineage cells in the anterior corpus callosum. Brain structure & function. 2023-09-05. PMID:37668732. |
using rnascope, we further demonstrate that ~ 40% of olig2 + /pdfgra + cells and ~ 20% of olig2 + /pdgfra- cells in the anterior corpus callosum express drd1 and drd2 transcripts. |
2023-09-05 |
2023-09-07 |
mouse |
| Navina Suresh, Suvarna Jyothi Kantipudi, Deepika Ramu, Suresh Kumar Muniratnam, Vettriselvi Venkatesa. Association between opioid and dopamine receptor gene polymorphisms OPRM1rs1799971, DAT VNTR9-10 repeat allele, DRD1 rs4532 and DRD2 rs1799732 and alcohol dependence: an ethnicity oriented meta-analysis. Pharmacogenetics and genomics. 2023-07-19. PMID:37466123. |
we carried out a meta-analysis of four opioid and dopamine candidate gene polymorphisms having conflicting results in prior literature, namely oprm1 rs1799971, dat vntr9-10 repeat, drd1 rs4532 and drd2 rs1799732, to clarify their association with alcohol dependence and further stratified results by ethnicity to analyze possible ethnicity-mediated effects. |
2023-07-19 |
2023-08-14 |
Not clear |
| Ewa Ferensztajn-Rochowiak, Monika Dmitrzak-Węglarz, Aleksandra Szczepankiewicz, Maria Skibińska, Sebastian Kliwicki, Agnieszka Permoda-Pachuta, Aleksandra Suwalska, Piotr Czerski, Joanna Pawlak, Joanna Hause. Studies on candidate genes for lithium prophylaxis performed at the Poznan University of Medical Sciences. Psychiatria polska. vol 56. issue 5. 2023-04-19. PMID:37074853. |
the associations with lithium prophylactic efficacy were found for the polymorphisms in 5htt, acp1, arntl, bdnf, comt, drd1, fkbp5, fyn, glcc, nr3c1, and tim, genes, but not those in 5ht2a, 5ht2c, drd2, drd3, drd4, grin2b, gsk-3β, mmp-9, and ntrk2 genes. |
2023-04-19 |
2023-08-14 |
Not clear |
| Michał Szulc, Radosław Kujawski, Amanda Pacholak, Marta Poprawska, Kamila Czora-Poczwardowska, Bogna Geppert, Przemysław Ł Mikołajcza. Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats. Nutrients. vol 15. issue 7. 2023-04-13. PMID:37049542. |
in the prefrontal cortex, hippocampus, and striatum, the cannabinoid (cb1r and cb2r) and dopaminergic (drd1, drd2, drd4, drd5) receptors' mrna level changes were analyzed using the quantitative rt-pcr method. |
2023-04-13 |
2023-08-14 |
rat |
| Michał Szulc, Radosław Kujawski, Amanda Pacholak, Marta Poprawska, Kamila Czora-Poczwardowska, Bogna Geppert, Przemysław Ł Mikołajcza. Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats. Nutrients. vol 15. issue 7. 2023-04-13. PMID:37049542. |
for cb1r, drd1, and drd2 mrnas, the cbd + ethanol interaction produced opposite effects than for cb2r ones. |
2023-04-13 |
2023-08-14 |
rat |