Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jung Won Kwon, Kihwang Lee, Sang Wha Kim, Jisu Park, Jung Joo Hong, Jeong-Hwan Che, Seung Hyeok Seo. Therapeutic potential of histamine H Scientific reports. vol 14. issue 1. 2024-09-30. PMID:39349555. |
therapeutic potential of histamine h diabetic retinopathy (dr) is a prevalent complication of diabetes, often resulting in vision loss and blindness. |
2024-09-30 |
2024-10-03 |
Not clear |
Tianhao Zhou, Vik Meadows, Debjyoti Kundu, Konstantina Kyritsi, Travis Owen, Ludovica Ceci, Guido Carpino, Paolo Onori, Eugenio Gaudio, Nan Wu, Shannon Glaser, Burcin Ekser, Gianfranco Alpini, Lindsey Kennedy, Heather Franci. Mast cells selectively target large cholangiocytes during biliary injury via H2HR-mediated cAMP/pERK1/2 signaling. Hepatology communications. 2022-07-08. PMID:35799467. |
bile ducts are heterogenous in structure and function, and primary sclerosing cholangitis (psc) damages specific bile ducts leading to ductular reaction (dr), mast cell (mc) infiltration, increased histamine release, inflammation, and fibrosis. |
2022-07-08 |
2023-08-14 |
Not clear |
Graham Low. Dr James Riley, pioneer in histamine and mast cell studies. The journal of the Royal College of Physicians of Edinburgh. vol 49. issue 3. 2020-06-22. PMID:31497796. |
dr james riley, pioneer in histamine and mast cell studies. |
2020-06-22 |
2023-08-13 |
human |
Graham Low. Dr James Riley, pioneer in histamine and mast cell studies. The journal of the Royal College of Physicians of Edinburgh. vol 49. issue 3. 2020-06-22. PMID:31497796. |
riley and pharmacologist dr geoffrey west went on to galvanise this area of study by showing in a notable series of experiments that the mast cell granules are also the main repository of histamine, a key participant in allergic and anaphylactic reactions. |
2020-06-22 |
2023-08-13 |
human |
Jennifer M Spaethling, David Piel, Hannah Dueck, Peter T Buckley, Jacqueline F Morris, Stephen A Fisher, Jaehee Lee, Jai-Yoon Sul, Junhyong Kim, Tamas Bartfai, Sheryl G Beck, James H Eberwin. Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 2. 2014-03-27. PMID:24192459. |
using these data to inform our selection of receptors to assess, we found that oxytocin and lysophosphatidic acid 1 receptors are translated and active in costimulating, with the α1-adrenergic receptor, the firing of dr 5-ht neurons, while the effects of histamine are inhibitory and exerted at h3 histamine receptors. |
2014-03-27 |
2023-08-12 |
Not clear |
B L Jones, G L Kearn. Histamine: new thoughts about a familiar mediator. Clinical pharmacology and therapeutics. vol 89. issue 2. 2011-02-28. PMID:21178984. |
this is evidenced in part by the awarding of the 1936 nobel prize in physiology or medicine to sir henry hallett dale and dr otto loewi who discovered the actions of histamine and the 1957 nobel prize in physiology or medicine to pharmacologist dr daniel bovet who discovered the first antihistamine, pyrilamine (neoantergan)(1). |
2011-02-28 |
2023-08-12 |
Not clear |
T Kenaki. What systems can and can't do. British journal of pharmacology. vol 153. issue 5. 2008-05-15. PMID:18204481. |
this commentary discusses a paper in this issue by dr jillian baker on the antagonism of histamine h(2) receptors. |
2008-05-15 |
2023-08-12 |
Not clear |
M Cutaia, P Friedrich, R J Porcell. Reversal of vascular tachyphylaxis to catecholamines and histamine in the feline lung. The American review of respiratory disease. vol 137. issue 6. 1989-01-25. PMID:2849331. |
in addition, histamine demonstrated a significant increase in ed50 from dr i to iv, which suggested a loss of sensitivity. |
1989-01-25 |
2023-08-11 |
cat |
M Cutaia, P Friedrich, R J Porcell. Reversal of vascular tachyphylaxis to catecholamines and histamine in the feline lung. The American review of respiratory disease. vol 137. issue 6. 1989-01-25. PMID:2849331. |
the loss of reactivity to histamine was not secondary to changes in circulating catecholamine levels, because the plasma catecholamine levels before dr i and immediately following dr v in a subset of animals (n = 5) were within the reported normal range for this species. |
1989-01-25 |
2023-08-11 |
cat |
M Cutaia, P Friedrich, R J Porcell. Reversal of vascular tachyphylaxis to catecholamines and histamine in the feline lung. The American review of respiratory disease. vol 137. issue 6. 1989-01-25. PMID:2849331. |
all the experiments with norepinephrine (n = 6), epinephrine (n = 10), and histamine (n = 25) demonstrated a progressive loss of vasopressor activity as shown by reductions in the maximum response and slope between dr i to iv. |
1989-01-25 |
2023-08-11 |
cat |
M Cutaia, P Friedrich, R J Porcell. Reversal of vascular tachyphylaxis to catecholamines and histamine in the feline lung. The American review of respiratory disease. vol 137. issue 6. 1989-01-25. PMID:2849331. |
the loss of vasoconstrictor activity to histamine and the catecholamines was restored by the administration of propranolol prior to dr v. in contrast, cimetidine did not restore the initial vasopressor activity of histamine. |
1989-01-25 |
2023-08-11 |
cat |