| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M H Wilson, L E Limbir. Mechanisms regulating the cell surface residence time of the alpha 2A-adrenergic receptor. Biochemistry. vol 39. issue 4. 2000-02-23. PMID:10651634. |
in contrast, the shorter surface t(1/2) of the delta 3i alpha(2a)ar, whose cell surface t(1/2) and steady state density were not altered by ligand occupancy, occurred in the context of a structurally stable receptor in detergent solution. |
2000-02-23 |
2023-08-12 |
Not clear |
| S Wilkens, J Zhou, R Nakayama, S D Dunn, R A Capald. Localization of the delta subunit in the Escherichia coli F(1)F(0)-ATPsynthase by immuno electron microscopy: the delta subunit binds on top of the F(1). Journal of molecular biology. vol 295. issue 3. 2000-02-18. PMID:10623533. |
the images show that the antibody is bound at the very top of the f(1) domain indicating that at least part of delta is bound in the dimple formed by the n termini of the alpha and beta subunits. |
2000-02-18 |
2023-08-12 |
Not clear |
| T Hisayama, M Inomoto, Y Hioki, H Fuku. [Identification of PKC isozymes and effect of knockdown of PKC alpha by antisense oligodeoxynucleotide on iNOS expression via interleukin-1 receptor in vascular smooth muscle cells]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 114 Suppl 1. 2000-02-16. PMID:10629861. |
western blot analysis revealed the presence of cpkc (alpha), npkcs (delta and epsilon) and apkcs (tau and lambda). |
2000-02-16 |
2023-08-12 |
rat |
| M G Bixel, M Krauss, Y Liu, M L Bolognesi, M Rosini, I S Mellor, P N Usherwood, C Melchiorre, K Nakanishi, F Huch. Structure-activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor. European journal of biochemistry. vol 267. issue 1. 2000-02-15. PMID:10601857. |
to elucidate the site of phtx binding, a photolabile, radioactive phtx derivative was photocross-linked to the nachr in its closed channel conformation resulting in labeling yields for the two alpha and the beta, gamma and delta subunits of 10.4, 11.1, 4.0 and 7.4%, respectively. |
2000-02-15 |
2023-08-12 |
Not clear |
| A M Caccuri, G Antonini, P G Board, M W Parker, M Nicotra, M Lo Bello, G Federici, G Ricc. Proton release on binding of glutathione to alpha, Mu and Delta class glutathione transferases. The Biochemical journal. vol 344 Pt 2. 2000-02-11. PMID:10567224. |
the delta gst, which is closely related to the mammalian theta class enzymes and is distantly related to alpha and mu gsts in the evolutionary pathway, might display a different activation mechanism for gsh. |
2000-02-11 |
2023-08-12 |
Not clear |
| J Weber-Arden, O M Wilbert, D Kabelitz, B Arde. V delta repertoire during thymic ontogeny suggests three novel waves of gamma delta TCR expression. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 2. 2000-02-10. PMID:10623850. |
neonatal delta-chain transcripts used a second wave of diverse v alpha gene segments that are exclusively located in the delta locus-proximal gene cluster of intermingled single members of different v alpha subfamilies. |
2000-02-10 |
2023-08-12 |
Not clear |
| M J Yi, T H Kim, S J Lee, C K Cho, I H Bae, Y S Le. Radiation augments a sequential program of differentiation in PKC inhibitor- pretreated mouse epidermal cells. Journal of radiation research. vol 40. issue 3. 2000-02-04. PMID:10641489. |
radiation also induced pkc alpha expression in sts pretreated cells, independent of ca(2+)-shift, as well as altered expressions of pkc delta and -eta, while expressions of pkc alpha, -delta, -epsilon, and -eta were enhanced in v-rasha transformed cells. |
2000-02-04 |
2023-08-12 |
mouse |
| E Kocsis, M Kessel, E DeMoll, D A Graham. Structure of the Ni/Fe-S protein subcomponent of the acetyl-CoA decarbonylase/synthase complex from Methanosarcina thermophila at 26-A resolution. Journal of structural biology. vol 128. issue 2. 2000-02-02. PMID:10600570. |
the complex is composed of five different subunits, with a probable stoichiometry of alpha(8)beta(8)gamma(8)delta(8)epsilon(8). |
2000-02-02 |
2023-08-12 |
Not clear |
| S J Diede, D E Gottschlin. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. vol 99. issue 7. 2000-02-01. PMID:10619426. |
telomerase-mediated telomere addition in vivo requires dna primase and dna polymerases alpha and delta. |
2000-02-01 |
2023-08-12 |
Not clear |
| S J Diede, D E Gottschlin. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. vol 99. issue 7. 2000-02-01. PMID:10619426. |
telomere addition was detected in m phase arrested cells, which permitted us to determine that the essential dna polymerases alpha and delta and dna primase were required. |
2000-02-01 |
2023-08-12 |
Not clear |
| A Chadha, L G Dawson, P G Jenner, S Dut. Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus. Neuroscience. vol 95. issue 1. 2000-01-31. PMID:10619468. |
this study examined whether changes in expression of the genes encoding known gaba(a) receptor subunits (alpha(1-4), beta(1-3), gamma(1-3) and delta) could account for this receptor plasticity using a rodent model of parkinson's disease with a 6-hydroxydopamine-induced nigrostriatal lesion. |
2000-01-31 |
2023-08-12 |
Not clear |
| X J Chen, G D Clark-Walke. Alpha and beta subunits of F1-ATPase are required for survival of petite mutants in Saccharomyces cerevisiae. Molecular & general genetics : MGG. vol 262. issue 4-5. 2000-01-31. PMID:10628876. |
inactivation of either the alpha or beta subunit, but not the gamma, delta, or epsilon subunit of f1, renders cells petite-negative. |
2000-01-31 |
2023-08-12 |
Not clear |
| G L Mendes, A R Santos, A Malheiros, V C Filho, R A Yunes, J B Calixt. Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial. The Journal of pharmacology and experimental therapeutics. vol 292. issue 1. 2000-01-27. PMID:10604944. |
the mechanism by which polygodial produces antinociception seems likely to involve an interaction with the opioid system, mainly kappa and delta subtypes, depend on the activation of g(i/o) protein sensitive to pertussis toxin, alpha(1)-adrenoceptors, and the serotoninergic system. |
2000-01-27 |
2023-08-12 |
mouse |
| D L Burgess, C F Davis, L A Gefrides, J L Noebel. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome research. vol 9. issue 12. 2000-01-27. PMID:10613843. |
ten paralogous genes have been identified that encode isoforms of the alpha(1) subunit, four that encode beta subunits, and three that encode alpha(2)delta subunits. |
2000-01-27 |
2023-08-12 |
mouse |
| T Lehne. Immunopathogenesis of Behçet's disease. Annales de medecine interne. vol 150. issue 6. 2000-01-19. PMID:10615534. |
microbial infection induced stress upregulates hsp65 and mica gene product which stimulate gamma delta and alpha beta t cell receptor positive cells, to generate effector and suppressor t cells (fig. |
2000-01-19 |
2023-08-12 |
human |
| M Filizola, L Laakkonen, G H Loe. 3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors. Protein engineering. vol 12. issue 11. 2000-01-18. PMID:10585498. |
refined 3d models of the transmembrane domains of the cloned delta, mu and kappa opioid receptors belonging to the superfamily of g-protein coupled receptors (gpcrs) were constructed from a multiple sequence alignment using the alpha carbon template of rhodopsin recently reported. |
2000-01-18 |
2023-08-12 |
mouse |
| I Corre, H Baumann, S Hermoue. Regulation by Gi2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3. Oncogene. vol 18. issue 46. 2000-01-10. PMID:10597233. |
we found that tyrosine phosphorylation of stat3, also activated by csf-1r/v-fms, was inhibited in alpha i2-g204a/v-fms cells; in addition, expression of an 85 kda, c-terminal truncated form of stat3 (stat3 delta) was constitutively increased. |
2000-01-10 |
2023-08-12 |
Not clear |
| S B Smith, H C Ee, J R Conners, M S Germa. Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development. Molecular and cellular biology. vol 19. issue 12. 2000-01-06. PMID:10567552. |
in the absence of pax4, the numbers of insulin-producing beta cells and somatostatin-producing delta cells are drastically reduced, while the numbers of glucagon-producing alpha cells are increased. |
2000-01-06 |
2023-08-12 |
mouse |
| A C Hausrath, G Grüber, B W Matthews, R A Capald. Structural features of the gamma subunit of the Escherichia coli F(1) ATPase revealed by a 4.4-A resolution map obtained by x-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 24. 2000-01-06. PMID:10570135. |
the bacterial f(1) consists of five subunits with stoichiometry alpha(3), beta(3), gamma, delta, and epsilon. |
2000-01-06 |
2023-08-12 |
rat |
| K Ohshima, J Suzumiya, M Sugihara, M Kanda, K Shimazaki, C Kawasaki, S Haraoka, M Kikuch. Clinical, immunohistochemical and phenotypic features of aggressive nodal cytotoxic lymphomas, including alpha/beta, gamma/delta T-cell and natural killer cell types. Virchows Archiv : an international journal of pathology. vol 435. issue 2. 2000-01-06. PMID:10599306. |
cytotoxic cells include natural killer (nk) cells and cytotoxic alpha beta and gamma delta t lymphocytes (ctls). |
2000-01-06 |
2023-08-12 |
Not clear |