| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Brawek, M Löffler, D J Dooley, A Weyerbrock, T J Feuerstei. Differential modulation of K(+)-evoked (3)H-neurotransmitter release from human neocortex by gabapentin and pregabalin. Naunyn-Schmiedeberg's archives of pharmacology. vol 376. issue 5. 2008-04-03. PMID:18074120. |
such alpha(2)delta ligands appear to be selective modulators of the release of certain, but not all, neurotransmitters. |
2008-04-03 |
2023-08-12 |
human |
| Adam R Clarke, Robert J Barry, Patrick C L Heaven, Rory McCarthy, Mark Selikowitz, Mitchell K Byrn. EEG coherence in adults with attention-deficit/hyperactivity disorder. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 67. issue 1. 2008-04-01. PMID:18029040. |
waveshape coherence was calculated for 8 intrahemispheric electrode pairs (4 in each hemisphere), and 8 interhemispheric electrode pairs, within each of the delta, theta, alpha and beta bands. |
2008-04-01 |
2023-08-12 |
Not clear |
| Priya Xavier, Khosrow Behbehani, Donald Watenpaugh, John R Bur. Detecting electroencephalography variations due to sleep disordered breathing events. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2007. 2008-03-28. PMID:18003406. |
the normalized power changes between the frequency bands delta, theta, alpha and sigma were calculated using the welch averaging periodogram method between 10 s of eeg data before the event termination and 10 s of eeg data after event termination. |
2008-03-28 |
2023-08-12 |
human |
| Priya Xavier, Khosrow Behbehani, Donald Watenpaugh, John R Bur. Detecting electroencephalography variations due to sleep disordered breathing events. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2007. 2008-03-28. PMID:18003406. |
a significant decrease in normalized delta power (1-4 hz) (p=1.34e-06) and a significant increase in normalized theta (4-8 hz) (p=0.0002), alpha (8-12 hz) (p=0.0001) and sigma (12-16 hz) (p=0.0007) powers were observed across the event terminations. |
2008-03-28 |
2023-08-12 |
human |
| Katsuyo Ohashi, Mitsuhisa Kawai, Noriko Ninomiya, Charles Taylor, Yoichi Kurebayash. Effect of a new alpha 2 delta ligand PD-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats. Pharmacology. vol 81. issue 2. 2008-03-25. PMID:17989503. |
effect of a new alpha 2 delta ligand pd-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats. |
2008-03-25 |
2023-08-12 |
rat |
| Katsuyo Ohashi, Mitsuhisa Kawai, Noriko Ninomiya, Charles Taylor, Yoichi Kurebayash. Effect of a new alpha 2 delta ligand PD-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats. Pharmacology. vol 81. issue 2. 2008-03-25. PMID:17989503. |
pd-217014, a new gaba analog (1 alpha,3 alpha,5 alpha-3-aminomethyl-bicyclo[3.2.0]heptane-3-acetic acid), inhibited [(3)h]-gabapentin binding to alpha(2)delta subunit of voltage-gated calcium channels in a concentration-dependent manner (k(i) = 18 nmol/l). |
2008-03-25 |
2023-08-12 |
rat |
| Katsuyo Ohashi, Mitsuhisa Kawai, Noriko Ninomiya, Charles Taylor, Yoichi Kurebayash. Effect of a new alpha 2 delta ligand PD-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats. Pharmacology. vol 81. issue 2. 2008-03-25. PMID:17989503. |
these results indicate that pd-217014 is a potent alpha(2)delta ligand and possesses visceral analgesic activity. |
2008-03-25 |
2023-08-12 |
rat |
| Susanne A Gatz, Lisa Wiesmülle. Take a break--resveratrol in action on DNA. Carcinogenesis. vol 29. issue 2. 2008-03-25. PMID:18174251. |
however, results demonstrating rv-dependent dna breakage in the presence of cu(ii) ions and inhibition of dna polymerases alpha and delta produced some controversy regarding rv's role as a caretaker compound. |
2008-03-25 |
2023-08-12 |
Not clear |
| Fan Jia, Minerva Yue, Dev Chandra, Gregg E Homanics, Peter A Goldstein, Neil L Harriso. Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus. The Journal of pharmacology and experimental therapeutics. vol 324. issue 3. 2008-03-24. PMID:18094320. |
in addition, isoflurane directly activated alpha(4)beta(2)delta gaba(a)-rs expressed in human embryonic kidney 293 cells, and it was more potent at alpha(4)beta(2)delta than at alpha(1)beta(2)gamma(2) receptors (the presumptive extrasynaptic and synaptic gaba(a)-r subtypes in vb neurons). |
2008-03-24 |
2023-08-12 |
mouse |
| Amine Sadok, Véronique Bourgarel-Rey, Florence Gattacceca, Claude Penel, Maxime Lehmann, Hervé Kovaci. Nox1-dependent superoxide production controls colon adenocarcinoma cell migration. Biochimica et biophysica acta. vol 1783. issue 1. 2008-03-19. PMID:18023288. |
we conclude that nox1 activation by arachidonic acid metabolism occurs through 12-lipoxygenase and protein kinase c delta, and controls cell migration by affecting integrin alpha 2 subunit turn-over. |
2008-03-19 |
2023-08-12 |
Not clear |
| Zhiguo He, Xuehui Xie, Shengmu Xiao, Jianshe Liu, Guanzhou Qi. Microbial diversity of mine water at Zhong Tiaoshan copper mine, China. Journal of basic microbiology. vol 47. issue 6. 2008-03-18. PMID:18072249. |
phylogenetic analysis indicated that 60.62% of the clones were affiliated with members of the proteobacteria (alpha -3.10%, beta -24.78%, gamma -31.41%, delta -1.33%), whereas 29.20% of the clones were closely related to the nitrospira (leptospirillum ferrooxidans 20.80%, leptospirillum ferriphilum 0.88% and leptospirillum group iii 7.52%, respectively). |
2008-03-18 |
2023-08-12 |
Not clear |
| Zhaoyang Chen, Hongwei Hao, Luming Li, Jie Don. Wavelet transform for rabbit EEG with vagus nerve electric stimulation. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-17. PMID:17946063. |
the delta, theta, alpha and beta waves are obtained to better understand the stimulation effects on the brain. |
2008-03-17 |
2023-08-12 |
rabbit |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
phasic inhibition is mediated by synaptic gaba(a)rs that are mainly comprised of alpha(1), beta(2), and gamma(2) subunits, whereas tonic inhibition is mediated by extrasynaptic gaba(a)rs comprised of alpha(4/6), beta(2), and delta subunits. |
2008-03-17 |
2023-08-12 |
Not clear |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
we investigated the activation properties of recombinant alpha(4)beta(2)delta and alpha(1)beta(2)gamma(2s) gaba(a)rs in response to gaba and 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3(2h)-one (thip) using electrophysiological recordings from outside-out membrane patches. |
2008-03-17 |
2023-08-12 |
Not clear |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
rapid agonist application experiments indicated that thip produced faster opening rates at alpha(4)beta(2)delta gaba(a)rs (beta approximately 1600 s(-1)) than at alpha(1)beta(2)gamma(2s) gaba(a)rs (beta approximately 460 s(-1)), whereas gaba activated alpha(1)beta(2)gamma(2s) gaba(a)rs more rapidly (beta approximately 1800 s(-1)) than alpha(4)beta(2)delta gaba(a)rs (beta < 440 s(-1)). |
2008-03-17 |
2023-08-12 |
Not clear |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
single channel recordings of alpha(1)beta(2)gamma(2s) and alpha(4)beta(2)delta gaba(a)rs showed that both channels open to a main conductance state of approximately 25 ps at -70 mv when activated by gaba and low concentrations of thip, whereas saturating concentrations of thip elicited approximately 36 ps openings at both channels. |
2008-03-17 |
2023-08-12 |
Not clear |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
saturating concentrations of gaba elicited brief (<10 ms) openings with low intraburst open probability (p(o) approximately 0.3) at alpha(4)beta(2)delta gaba(a)rs and at least two "modes" of single channel bursting activity, lasting approximately 100 ms at alpha(1)beta(2)gamma(2s) gaba(a)rs. |
2008-03-17 |
2023-08-12 |
Not clear |
| Angelo Keramidas, Neil L Harriso. Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptors. The Journal of general physiology. vol 131. issue 2. 2008-03-17. PMID:18227274. |
single channel activity elicited by thip in alpha(4)beta(2)delta and alpha(1)beta(2)gamma(2s) gaba(a)rs occurred as a single population of bursts (p(o) approximately 0.4-0.5) of moderate duration (approximately 33 ms) that could be described by schemes containing two shut and two open states for both gaba(a)rs. |
2008-03-17 |
2023-08-12 |
Not clear |
| Jane S Richardson, Bohdan Schneider, Laura W Murray, Gary J Kapral, Robert M Immormino, Jeffrey J Headd, David C Richardson, Daniela Ham, Eli Hershkovits, Loren Dean Williams, Kevin S Keating, Anna Marie Pyle, David Micallef, John Westbrook, Helen M Berma. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA (New York, N.Y.). vol 14. issue 3. 2008-03-11. PMID:18192612. |
the conformers are given two-character names that reflect the seven-angle delta epsilon zeta alpha beta gamma delta combinations empirically found favorable for the sugar-to-sugar "suite" unit within which the angle correlations are strongest (e.g., 1a for a-form, 5z for the start of s-motifs). |
2008-03-11 |
2023-08-12 |
Not clear |
| Jane S Richardson, Bohdan Schneider, Laura W Murray, Gary J Kapral, Robert M Immormino, Jeffrey J Headd, David C Richardson, Daniela Ham, Eli Hershkovits, Loren Dean Williams, Kevin S Keating, Anna Marie Pyle, David Micallef, John Westbrook, Helen M Berma. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA (New York, N.Y.). vol 14. issue 3. 2008-03-11. PMID:18192612. |
since the half-nucleotides are specified by a number for delta epsilon zeta and a lowercase letter for alpha beta gamma delta, this modular system can also be parsed to describe traditional nucleotide units (e.g., a1) or the dinucleotides (e.g., a1a1) that are especially useful at the level of crystallographic map fitting. |
2008-03-11 |
2023-08-12 |
Not clear |