| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arippa Ravindran, Qi Zong Lao, Jo Beth Harry, Parwiz Abrahimi, Evgeny Kobrinsky, Nikolai M Soldato. Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 23. 2008-06-27. PMID:18535142. |
here, we describe a surprising discovery that coexpression of exogenous cam (cam(ex)) with alpha(1c)/alpha(2)delta in cos1 cells in the absence of ca(v)beta subunits stimulates the plasma membrane targeting of alpha(1c), facilitates calcium channel gating, and supports ca2+-dependent inactivation. |
2008-06-27 |
2023-08-12 |
monkey |
| Daniel J Clau. Pharmacotherapy for patients with fibromyalgia. The Journal of clinical psychiatry. vol 69 Suppl 2. 2008-06-27. PMID:18537460. |
despite research detailing the efficacy of a variety of medicinal treatments, most notably, tricyclic antidepressants, serotonin-norepinephrine re-uptake inhibitors, and alpha(2)delta ligands, there is still widespread, routine use of agents that are mostly ineffective in treating the central nature of fibromyalgic pain. |
2008-06-27 |
2023-08-12 |
Not clear |
| Annina Lyly, Sanna K Marjavaara, Aija Kyttälä, Kristiina Uusi-Rauva, Kaisu Luiro, Outi Kopra, Laurent O Martinez, Kimmo Tanhuanpää, Nisse Kalkkinen, Anu Suomalainen, Matti Jauhiainen, Anu Jalank. Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism. Human molecular genetics. vol 17. issue 10. 2008-06-23. PMID:18245779. |
while no changes in the mitochondrial function could be detected in the brain of the ppt1(delta ex4) mice, the levels of f(1)-subunits alpha and beta on the plasma membrane were specifically increased in the ppt1(delta ex4) neurons. |
2008-06-23 |
2023-08-12 |
mouse |
| Owen W Nadeau, Gerald J Wyckoff, Justin E Paschall, Antonio Artigues, Jessica Sage, Maria T Villar, Gerald M Carlso. CrossSearch, a user-friendly search engine for detecting chemically cross-linked peptides in conjugated proteins. Molecular & cellular proteomics : MCP. vol 7. issue 4. 2008-06-23. PMID:18281724. |
using this strategy, the (alpha beta gamma delta)(4) phosphorylase kinase model complex was cross-linked to form with high specificity a 170-kda betagamma conjugate in which we identified residues involved in the intramolecular cross-linking of the 125-kda beta subunit between its regulatory n terminus and its c terminus. |
2008-06-23 |
2023-08-12 |
Not clear |
| N V Ponomareva, G I Korovaitseva, E I Rogae. EEG alterations in non-demented individuals related to apolipoprotein E genotype and to risk of Alzheimer disease. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17293007. |
under hyperventilation the presence of the epsilon4 allele in ad relatives was associated with the manifestation of synchronous high-voltage delta-, theta-activity and sharp-waves, pronounced decrease in alpha and increase in delta and theta relative powers. |
2008-06-20 |
2023-08-12 |
Not clear |
| Nicolas Jonckheere, Erin Mayes, Hung-Ping Shih, Boan Li, Oleg Lioubinski, Xing Dai, Maike Sande. Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Developmental biology. vol 318. issue 2. 2008-06-18. PMID:18452912. |
consistent with its function after e12.5, late-developing endocrine cell types, such as beta, delta and pp cells, are specifically reduced, while the earlier-forming alpha cells develop normally. |
2008-06-18 |
2023-08-12 |
mouse |
| T Lookman, A Saxena, R C Alber. Phonon mechanisms and transformation paths in Pu. Physical review letters. vol 100. issue 14. 2008-06-17. PMID:18518047. |
a long-standing problem in pu science is the crystallographic mechanism for the delta-->alpha' (fcc-->monoclinic) transformation. |
2008-06-17 |
2023-08-12 |
Not clear |
| T Lookman, A Saxena, R C Alber. Phonon mechanisms and transformation paths in Pu. Physical review letters. vol 100. issue 14. 2008-06-17. PMID:18518047. |
we suggest that the delta-->alpha' transition in pu lies at the threshold of a change in character of the orientation relationship from lighter to heavier actinides, correlating with changes in electron itinerancy, magnetism, and volume. |
2008-06-17 |
2023-08-12 |
Not clear |
| Austin Samakande, Radhouane Chaghi, Gaelle Derrien, Clarence Charnay, Patrice C Hartman. Aqueous behaviour of cationic surfactants containing a cleavable group. Journal of colloid and interface science. vol 320. issue 1. 2008-06-16. PMID:18243236. |
the critical micelle concentration (cmc), the degree of micelle ionization (alpha), the head group surface area (a 0), delta h mic, delta g mic and t delta s mic are reported at 303 k. the thermodynamic parameters have been compared to those of the conventional surfactant cetyltrimethylammonium bromide (ctab) in order to specify structural relationships. |
2008-06-16 |
2023-08-12 |
Not clear |
| Minoru Murata, Etsuko Yokota, Fukashi Shibata, Kazunari Kashihar. Functional analysis of the Arabidopsis centromere by T-DNA insertion-induced centromere breakage. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 21. 2008-06-16. PMID:18495926. |
two minichromosomes (alpha and delta) in addition to two other aberrant chromosomes (beta and gamma) were found in a transgenic arabidopsis plant produced by an in planta vacuum infiltration technique. |
2008-06-16 |
2023-08-12 |
Not clear |
| Minoru Murata, Etsuko Yokota, Fukashi Shibata, Kazunari Kashihar. Functional analysis of the Arabidopsis centromere by T-DNA insertion-induced centromere breakage. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 21. 2008-06-16. PMID:18495926. |
the mini alpha chromosome contained the whole short-arm 2s and a truncated centromere (180-bp repeat cluster), whereas mini delta lacked the terminal region including telomere repeats. |
2008-06-16 |
2023-08-12 |
Not clear |
| Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushin. 1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Bioorganic & medicinal chemistry. vol 16. issue 6. 2008-06-13. PMID:18178092. |
on the other hand, compounds 1 and 2 did not influence the activities of the other families of eukaryotic pols, such as family a (i.e., pol gamma) and family b (i.e., pols alpha, delta, and epsilon), and showed no effect even on the activities of plant pols alpha and beta, prokaryotic pols, and other dna metabolic enzymes, such as calf primase of pol alpha, human immunodeficiency virus type-1 (hiv-1) reverse transcriptase, human telomerase, t7 rna polymerase, mouse imp dehydrogenase (type ii), human topoisomerase i and ii, t4 polynucleotide kinase, and bovine deoxyribonuclease i. |
2008-06-13 |
2023-08-12 |
mouse |
| Mark P Jensen, Shahin Hakimian, Leslie H Sherlin, Felipe Fregn. New insights into neuromodulatory approaches for the treatment of pain. The journal of pain. vol 9. issue 3. 2008-06-12. PMID:18096437. |
specifically, this research suggests that the subjective experience of pain is associated with relatively lower amplitudes of slower wave (delta, theta, and alpha) activity and relatively higher amplitudes of faster wave (beta) activity. |
2008-06-12 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
the ivs6+1g>t prkar1a mutation leads to a protein lacking exon 6 sequences [r1 alpha delta 184-236 (r1 alpha delta 6)]. |
2008-06-10 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
we compared in vitro r1 alpha delta 6 with wild-type (wt) r1 alpha. |
2008-06-10 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
introduction of the r1 alpha delta 6 led to aberrant cellular morphology and higher pka activity but no increase in type ii pka subunits. |
2008-06-10 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
there was diffuse, cytoplasmic localization of r1 alpha protein in wt-r1 alpha- and r1 alpha delta 6-transfected cells but the former also exhibited discrete aggregates of r1 alpha that bound c alpha; these were absent in r1 alpha delta 6-transfected cells and did not bind c alpha at baseline or in response to cyclic amp. |
2008-06-10 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
other changes induced by r1 alpha delta 6 included decreased nuclear c alpha. |
2008-06-10 |
2023-08-12 |
Not clear |
| Elise Meoli, Ioannis Bossis, Laure Cazabat, Manos Mavrakis, Anelia Horvath, Sotiris Stergiopoulos, Miriam L Shiferaw, Glawdys Fumey, Karine Perlemoine, Michael Muchow, Audrey Robinson-White, Frank Weinberg, Maria Nesterova, Yianna Patronas, Lionel Groussin, Jérôme Bertherat, Constantine A Strataki. Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer research. vol 68. issue 9. 2008-06-10. PMID:18451138. |
we conclude that r1 alpha delta 6 leads to increased pka activity through the mt-r1 alpha decreased binding to c alpha and does not involve changes in other pka subunits, suggesting that a switch to type ii pka activity is not necessary for increased kinase activity or tumorigenesis. |
2008-06-10 |
2023-08-12 |
Not clear |
| Dafin F Muresanu, X Anton Alvarez, Herbert Moessler, Manuel Buia, Adina Stan, Daniela Pintea, Florina Moldovan, Bogdan O Popesc. A pilot study to evaluate the effects of Cerebrolysin on cognition and qEEG in vascular dementia: cognitive improvement correlates with qEEG acceleration. Journal of the neurological sciences. vol 267. issue 1-2. 2008-06-02. PMID:18048059. |
baseline adas-cog scores showed significant positive correlations with delta power, theta power and pr scores, and correlated negatively with alpha activity. |
2008-06-02 |
2023-08-12 |
Not clear |