| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiangtao Cui, Shiyi Zhang, Kiran Acharya, Yan Xu, Heng Guo, Tong Li, Donghe Fu, Zizhen Yang, Lingnan Hou, Xiaotao Xing, Xiaoyi H. Decorin attenuates hypertrophic scar fibrosis via TGFβ/Smad signalling. Experimental dermatology. vol 33. issue 7. 2024-07-24. PMID:39045898. |
in our research, we observed a decrease in dcn expression within hypertrophic scar tissue and its derived cells (hsfc) compared to that in normal tissue. |
2024-07-24 |
2024-07-26 |
Not clear |
| Shanxi Wang, Yunkun Qu, Xuan Fang, Qing Ding, Hongqi Zhao, Xiaojun Yu, Tao Xu, Rui Lu, Shaoze Jing, Chaoxu Liu, Hua Wu, Yang Li. Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1. Experimental & molecular medicine. 2023-07-02. PMID:37394592. |
these findings imply that dcn is a potential therapeutic candidate for ligamentum flavum hypertrophy. |
2023-07-02 |
2023-08-14 |
human |
| Shanxi Wang, Yunkun Qu, Xuan Fang, Qing Ding, Hongqi Zhao, Xiaojun Yu, Tao Xu, Rui Lu, Shaoze Jing, Chaoxu Liu, Hua Wu, Yang Li. Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1. Experimental & molecular medicine. 2023-07-02. PMID:37394592. |
the dcn protein expression in hypertrophic lf samples was higher than that in non-lfh samples, but the difference was not significant. |
2023-07-02 |
2023-08-14 |
human |
| Haihan Chu, Yunpeng Wang, Xiuchun Wang, Xianhui Song, Huaqing Liu, Xue L. Effects of transplanted adipose derived stem cells on the expressions of α-SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186394. |
to study the effects of transplanted adipose derived stem cells (adscs) on the expressions of α-smooth muscle actin (α-sma) and decorin (dcn) in fibroblasts of hypertrophic scar tissues in rabbit ears. |
2020-10-01 |
2023-08-13 |
rabbit |
| Haihan Chu, Yunpeng Wang, Xiuchun Wang, Xianhui Song, Huaqing Liu, Xue L. Effects of transplanted adipose derived stem cells on the expressions of α-SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186394. |
effects of transplanted adipose derived stem cells on the expressions of α-sma and dcn in fibroblasts of hypertrophic scar tissues in rabbit ears. |
2020-10-01 |
2023-08-13 |
rabbit |
| Yue Shen, Matthew R Zeglinski, Christopher T Turner, Sheetal A Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R Cameron, Anthony Papp, David J Granvill. Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing. Experimental & molecular medicine. vol 50. issue 5. 2019-03-18. PMID:29849046. |
as dcn is anti-fibrotic and contributes to reduced hypertrophic scarring, gzmb-induced dcn cleavage could play a role in wound healing following burn injury. |
2019-03-18 |
2023-08-13 |
Not clear |
| Wenduo Zhang, Chengliang Deng, Changmin Guo, Kaiyu Nie, Xiujun Tang, Zairong Wei, Dali Wan. [Influences of human dermis derived mesenchymal stem cells on α-SMA and DCN expressions of hypertrophic scars fibroblasts]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 32. issue 4. 2018-08-06. PMID:30044575. |
to preliminarily explore the effects of human dermis derived mesenchymal stem cells (hdmscs) on expressions of α-smooth muscle actin (α-sma) and decorin (dcn) in hypertrophic scars fibroblasts (hsfb) at different periods,and to explore the feasibility of mscs in prevention and treatment of hsfbs. |
2018-08-06 |
2023-08-13 |
human |
| Wenduo Zhang, Chengliang Deng, Changmin Guo, Kaiyu Nie, Xiujun Tang, Zairong Wei, Dali Wan. [Influences of human dermis derived mesenchymal stem cells on α-SMA and DCN expressions of hypertrophic scars fibroblasts]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 32. issue 4. 2018-08-06. PMID:30044575. |
[influences of human dermis derived mesenchymal stem cells on α-sma and dcn expressions of hypertrophic scars fibroblasts]. |
2018-08-06 |
2023-08-13 |
human |
| Wen Yan, Peihua Wang, Chun Xia Zhao, Jiarong Tang, Xiao Xiao, Dao Wen Wan. Decorin gene delivery inhibits cardiac fibrosis in spontaneously hypertensive rats by modulation of transforming growth factor-beta/Smad and p38 mitogen-activated protein kinase signaling pathways. Human gene therapy. vol 20. issue 10. 2010-02-03. PMID:19697998. |
thus, these results suggest that raav-mediated dcn overexpression led to the inhibition of hypertension-induced cardiac fibrosis and hypertrophy and improved cardiac function, and therefore may have therapeutic potential for organ fibrosis. |
2010-02-03 |
2023-08-12 |
rat |