| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Kaplinsky, Reut Halperin, Gadi Shlomai, Amit Tiros. Role of epigenetic regulation on catecholamine synthesis in pheochromocytoma and paraganglioma. Cancer. 2024-06-14. PMID:38872410. |
catecholamines are synthesized by several enzymes: phenylalanine hydroxylase (encoded by pah), tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (ddc), dopamine β-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt). |
2024-06-14 |
2024-06-16 |
Not clear |
| Yoshiaki Soejima, Nahoko Iwata, Koichiro Yamamoto, Atsuhito Suyama, Yasuhiro Nakano, Fumio Otsuk. Mutual Effects of Orexin and Bone Morphogenetic Proteins on Catecholamine Regulation Using Adrenomedullary Cells. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338864. |
orexin a treatment reduced the mrna levels of key enzymes for catecholamine synthesis, including tyrosine hydroxylase (th), 3,4-dihydroxyphenylalanie decarboxylase (ddc) and dopamine β-hydroxylase (dbh), in a concentration-dependent manner. |
2024-02-10 |
2024-02-12 |
rat |
| Jovana Zlatkovic, Adrià Dalmau Gasull, Daniel Hägg, Ferran Font-Gironès, Jakob Bellman, Björn Meister, Vilborg Palsdottir, Johan Ruud, Claes Ohlsson, Suzanne L Dickson, Fredrik Anesten, John-Olov Jansso. Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract. Journal of neuroendocrinology. 2023-10-27. PMID:37885347. |
these neurones also expressed tyrosine hydroxylase (th) and dopamine-beta-hydroxylase (dbh), a pattern typical of norepinephrine neurones. |
2023-10-27 |
2023-11-08 |
mouse |
| Toshiharu Nagats. Catecholamines and Parkinson's disease: tyrosine hydroxylase (TH) over tetrahydrobiopterin (BH4) and GTP cyclohydrolase I (GCH1) to cytokines, neuromelanin, and gene therapy: a historical overview. Journal of neural transmission (Vienna, Austria : 1996). 2023-08-28. PMID:37638996. |
the author identified the genes and proteins of human enzymes involved in the biosynthesis of catecholamines (dopamine, norepinephrine, epinephrine) and tetrahydrobiopterin (bh4): tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), dopamine β-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt), and gtp cyclohydrolase i (gch1). |
2023-08-28 |
2023-09-07 |
human |
| Z Pidsudko, J Godlewski, K Wąsowic. The distribution and chemical coding of urinary bladder trigone-projecting neurons in testicular and aorticorenal ganglia in male pigs. Polish journal of veterinary sciences. vol 25. issue 3. 2022-09-26. PMID:36155594. |
the expression of tyrosine hydroxylase (th) or dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), nitric oxide synthase (nos) and vesicular acetylcholine transporter (vacht) were investigated. |
2022-09-26 |
2023-08-14 |
Not clear |
| Ayumi Sato, Takehiro Yajima, Daisuke Tachiya, Hiroyuki Ichikawa, Tadasu Sat. Innervation of the human minor salivary glands; immunohistochemical study for neurochemical substances. Tissue & cell. vol 79. 2022-09-20. PMID:36126414. |
distributions of choline acetyltransferase (chat), vasoactive intestinal polypeptide (vip), dopamine β-hydroxylase (dbh), tyrosine hydroxylase (th), neuropeptide y (npy) and the transient receptor potential cation channel subfamily v member 2 (trpv2) were examined in the human minor salivary glands. |
2022-09-20 |
2023-08-14 |
human |
| Agata Szlaga, Patryk Sambak, Anna Gugula, Aleksandra Trenk, Andrew L Gundlach, Anna Blasia. Catecholaminergic innervation and D2-like dopamine receptor-mediated modulation of brainstem nucleus incertus neurons in the rat. Neuropharmacology. 2022-08-16. PMID:35973599. |
our immunohistochemical and viral-based retrograde tract-tracing studies revealed a dense innervation of the ni area by fibers containing the catecholaminergic biosynthesis enzymes, tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh), and indicated the major sources of the catecholaminergic innervation of the ni as the darkschewitsch, raphe and hypothalamic a13 nuclei. |
2022-08-16 |
2023-08-14 |
rat |
| Kui Cui, Fan Yang, Turan Tufan, Muhammad U Raza, Yanqiang Zhan, Yan Fan, Fei Zeng, Russell W Brown, Jennifer B Price, Thomas C Jones, Gary W Miller, Meng-Yang Zh. Restoration of Noradrenergic Function in Parkinson's Disease Model Mice. ASN neuro. vol 13. 2021-11-30. PMID:33940943. |
biochemical analysis showed that microinjection of lentiviral expression cassettes into the lc significantly increased mrna levels of phox2a, and phox2b, which were accompanied by parallel increases of mrna and proteins of dopamine β-hydroxylase (dbh) and tyrosine hydroxylase (th) in the lc. |
2021-11-30 |
2023-08-13 |
mouse |
| Mutsuko Kawashima, Takehiro Yajima, Daisuke Tachiya, Souichi Kokubun, Hiroyuki Ichikawa, Tadasu Sat. Parasympathetic neurons in the human submandibular ganglion. Tissue & cell. vol 70. 2021-11-29. PMID:33517097. |
in this study, immunohistochemistry for vasoactive intestinal polypeptide (vip), neuropeptide y (npy), choline acetyltransferase (chat), dopamine β-hydroxylase (dbh), tyrosine hydroxylase (th), and the transient receptor potential cation channel subfamily v members 1 (trpv1) and 2 (trpv2) was performed on the human smg. |
2021-11-29 |
2023-08-13 |
human |
| Noriko Kimura, Kiyoto Shiga, Ken-Ichi Kaneko, Yutaka Oki, Chiho Sugisawa, Jun Saito, Seiich Tawara, Hiroshi Akahori, Susumu Sogabe, Takafumi Yamashita, Kazuhiro Takekoshi, Mitsuhide Naruse, Takayuki Katabam. Immunohistochemical Expression of Choline Acetyltransferase and Catecholamine-Synthesizing Enzymes in Head-and-Neck and Thoracoabdominal Paragangliomas and Pheochromocytomas. Endocrine pathology. vol 32. issue 4. 2021-11-23. PMID:34743284. |
to determine the phenotypic features of these pgls, we performed an immunohistochemical study using specific antibodies against choline acetyltransferase (chat), an enzyme involved in acetylcholine synthesis, and enzymes for the catecholamine-synthesis, tyrosine hydroxylase (th), and dopamine beta-hydroxylase (dbh), in 34 hnpgls from 31 patients, 12 thoracoabdominal pgls from 12 patients, and 26 pheochromocytomas from 22 patients. |
2021-11-23 |
2023-08-13 |
Not clear |
| Hayden Torres, Clara Huesing, David H Burk, Adrien J R Molinas, Winfried L Neuhuber, Hans-Rudolf Berthoud, Heike Münzberg, Andrei V Derbenev, Andrea Zsombo. Sympathetic innervation of the mouse kidney and liver arising from prevertebral ganglia. American journal of physiology. Regulatory, integrative and comparative physiology. vol 321. issue 3. 2021-09-16. PMID:34231420. |
we used tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh) reporter mice to visualize abdominal prevertebral ganglia. |
2021-09-16 |
2023-08-13 |
mouse |
| Zhong-Wen Chang, Yi-Chun Yeh, Chin-Chyuan Chan. Role of novel protein kinase C in neuroendocrine-immune regulatory network in haemocytes of Litopenaeus vannamei: An in vitro approach. Fish & shellfish immunology. vol 105. 2021-04-16. PMID:32645515. |
the same deviated pattern was observed in tyrosine, dopamine, and norepinephrine levels, and in dopamine β-hydroxylase (dbh) activity and gene expressions of tyrosine hydroxylase, dopa decarboxylase, and dbh involving in ba biosynthesis. |
2021-04-16 |
2023-08-13 |
Not clear |
| Yunxiao Li, Yongsheng Zhu, Jianghua Lai, Xugang Shi, Yuanyuan Chen, Jinyu Zhang, Shuguang We. Association studies of dopamine synthesis and metabolism genes with multiple phenotypes of heroin dependence. BMC medical genetics. vol 21. issue 1. 2020-10-28. PMID:32736537. |
this study aimed to identify the association between genetic polymorphisms of da synthesis and metabolism genes, including tyrosine hydroxylase (th), dopa decarboxylase (ddc), solute carrier family 6 member 3 (slc6a3) and da beta-hydroxylase (dbh), with six important phenotypes of heroin dependence. |
2020-10-28 |
2023-08-13 |
Not clear |
| Wiebke Bensmann, Nicolas Zink, Larissa Arning, Christian Beste, Ann-Kathrin Stoc. The Presynaptic Regulation of Dopamine and Norepinephrine Synthesis Has Dissociable Effects on Different Kinds of Cognitive Conflicts. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31183808. |
we investigated the effects of presynaptic differences in dopamine and norepinephrine synthesis with the help of the tyrosine hydroxylase (th) rs10770141 and the dopamine-β-hydroxylase (dbh) rs1611115, rs6271, and rs1611122 polymorphisms. |
2020-04-06 |
2023-08-13 |
human |
| Zhijuan Wang, Yedan Gai, Jinlian Zhou, Jiali Liu, Sheng Cu. miR-375 mediates the CRF signaling pathway to regulate catecholamine biosynthesis by targeting Sp1 in porcine adrenal gland. Stress (Amsterdam, Netherlands). vol 22. issue 3. 2020-02-18. PMID:30714474. |
functional studies showed that mir-375 negatively regulated cats synthesis in primary cells by affecting the expression of the cats synthetases tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine-n-methyltransferase (pnmt). |
2020-02-18 |
2023-08-13 |
mouse |
| Z Pidsudko, Ż Listowska, A Franke-Radowiecka, M Klimczuk, M Załęcki, J Kaleczy. Distribution and chemical coding of urinary bladder apex-projecting neurons in aorticorenal and testicular ganglia of the male pig. Polish journal of veterinary sciences. vol 22. issue 2. 2019-12-09. PMID:31269360. |
the presence of tyrosine hydroxylase (th) or dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), nitric oxide synthase (nos) and vesicular acetylcholine transporter (vacht) were investigated. |
2019-12-09 |
2023-08-13 |
Not clear |
| Bojana Stefanovic, Natasa Spasojevic, Predrag Jovanovic, Sladjana Dronja. Melatonin treatment affects changes in adrenal gene expression of catecholamine biosynthesizing enzymes and norepinephrine transporter in the rat model of chronic-stress-induced depression. Canadian journal of physiology and pharmacology. vol 97. issue 7. 2019-12-02. PMID:30773040. |
this entailed quantifying the norepinephrine, epinephrine, mrna, and protein levels of tyrosine hydroxylase (th), dopamine-β-hydroxylase (dbh), phenylethanolamine |
2019-12-02 |
2023-08-13 |
rat |
| A R Murtazina, Yu O Nikishina, L K Dil'mukhametova, A Ya Sapronova, M V Ugrumo. The Role of the Brain in the Regulation of Peripheral Noradrenaline-producing Organs in Rats During Morphogenesis. Doklady. Biochemistry and biophysics. vol 486. issue 1. 2019-08-29. PMID:31367831. |
in this study, we used a rat model that allowed blocking the synthesis of noradrenalin in the brain and evaluated gene expression and protein levels of noradrenaline key synthesis enzymes such as tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) in peripheral noradrenaline-producing organs. |
2019-08-29 |
2023-08-13 |
rat |
| Sachiko Konosu-Fukaya, Kei Omata, Yuta Tezuka, Yoshikiyo Ono, Yayoi Aoyama, Fumitoshi Satoh, Fumiyoshi Fujishima, Hironobu Sasano, Yasuhiro Nakamur. Catecholamine-Synthesizing Enzymes in Pheochromocytoma and Extraadrenal Paraganglioma. Endocrine pathology. vol 29. issue 4. 2019-04-05. PMID:30155766. |
in chromaffin cells, tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), dopamine β-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt) are mainly involved in catecholamine synthesis. |
2019-04-05 |
2023-08-13 |
Not clear |
| Stephanie Mandic, Hélène Volkof. The effects of fasting and appetite regulators on catecholamine and serotonin synthesis pathways in goldfish (Carassius auratus). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 223. 2019-03-15. PMID:29730451. |
in order to better understand the role of monoamine neurotransmitters in the regulation of feeding in fish, we examined the effects of fasting on the brain and intestine gene expression of enzymes involved in their synthesis pathways (spr: sepiapterin reductase; dhpr: dihydropteridine reductase; th: tyrosine hydroxylase; tph: tryptophan hydroxylase; aadc: aromatic l-amino acid decarboxylase; dbh: dopamine β-hydroxylase) in goldfish. |
2019-03-15 |
2023-08-13 |
Not clear |