| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emma-Jane Mallas, Sara De Simoni, Peter O Jenkins, Michael C B David, Niall J Bourke, David J Shar. Methylphenidate differentially alters corticostriatal connectivity after traumatic brain injury. Brain : a journal of neurology. 2024-10-21. PMID:39432756. |
123i-ioflupane spect dopamine transporter (dat) scans were performed, and specific binding ratios were extracted from caudate subdivisions. |
2024-10-21 |
2024-10-24 |
Not clear |
| Elnaz Khezerlou, Jacqueline Saenz, Sanjana Surya Prakash, Ping-Yue Pa. Protocol for live neuron imaging analysis of basal surface fraction and dynamic availability of the dopamine transporter using DAT-pHluorin. STAR protocols. vol 5. issue 4. 2024-10-05. PMID:39368094. |
surface availability of the dopamine (da) transporter (dat) critically influences da transmission. |
2024-10-05 |
2024-10-08 |
mouse |
| Hirotaka Sakuramoto, Hiroaki Fujita, Keitaro Ogaki, Keisuke Suzuk. Vascular parkinsonism showing dopamine transporter scan findings mimicking those of Parkinson's disease. eNeurologicalSci. vol 37. 2024-09-30. PMID:39346749. |
dopamine transporter (dat) scan is important in the diagnosis of parkinson's disease (pd). |
2024-09-30 |
2024-10-02 |
Not clear |
| Hirotaka Sakuramoto, Hiroaki Fujita, Keitaro Ogaki, Keisuke Suzuk. Vascular parkinsonism showing dopamine transporter scan findings mimicking those of Parkinson's disease. eNeurologicalSci. vol 37. 2024-09-30. PMID:39346749. |
we herein report a patient with vascular parkinsonism (vp) who showed dopamine transporter (dat) scan findings which mimicked those typically seen in patients with parkinson's disease (pd). |
2024-09-30 |
2024-10-02 |
Not clear |
| Ana Catya Jimenez-Torres, Jamison A Hastie, Sarah E Davis, Katherine D Porter, Bin Lei, Omar Moukha-Chafiq, Sixue Zhang, Theresa H Nguyen, Subramaniam Ananthan, Corinne E Augelli-Szafran, Jun Zh. The Journal of pharmacology and experimental therapeutics. 2024-09-16. PMID:39284625. |
we have demonstrated that sri-32742, a novel allosteric modulator of dopamine (da) transporter (dat), attenuates cocaine- and tat-binding to dat, alleviates tat-induced cognitive deficits and potentiation of cocaine reward in inducible tat transgenic mice. |
2024-09-16 |
2024-09-19 |
mouse |
| Salih Cayir, Melike Tezel, David Matuske. Socioenvironmental Factors are Associated With Dopamine Transporter Availability in Healthy Individuals but not in Parkinson's Disease. Journal of geriatric psychiatry and neurology. 2024-09-08. PMID:39244698. |
this study investigated the relationship between socioenvironmental factors and dopamine transporter (dat) availability in healthy individuals (n = 74) and those with parkinson's disease (pd) (n = 240). |
2024-09-08 |
2024-09-11 |
Not clear |
| Ryosuke Shimasaki, Masanori Kurihara, Keiko Hatano, Ryoji Goto, Kenichiro Taira, Ryoko Ihara, Mana Higashihara, Yasushi Nishina, Masashi Kameyama, Atsushi Iwat. Associations of cerebrospinal fluid monoamine metabolites with striatal dopamine transporter binding and Parkinsonism & related disorders. vol 128. 2024-09-06. PMID:39241507. |
although some reported associations between hva and striatal dopamine transporter (dat) or 5-hiaa and cardiac |
2024-09-06 |
2024-09-10 |
Not clear |
| Tomohiro Sato, Setsu Sawai, Naokazu Shimad. Comparison of the ability of different quantitative indices in Japanese journal of radiology. 2024-09-05. PMID:39235674. |
comparison of the ability of different quantitative indices in by imaging dopamine transporter (dat) uptake in the striatum, |
2024-09-05 |
2024-09-08 |
Not clear |
| Paul C Omaliko, Peter R Ferket, Tunde E Ogundare, Oluwabunmi O Apalowo, Ikenna G Enenya, Odinaka C Iwuozo, Jian Han, Yewande O Fasin. Impact of dietary fat types on expression levels of dopamine and serotonin transporters in the ileum of broiler chickens. Poultry science. vol 103. issue 11. 2024-08-30. PMID:39214056. |
a broiler chicken trial was conducted to evaluate the influence of dietary fat types on protein expression of 2 neurotransmitter transporters, dopamine (dat) and serotonin (5-htt). |
2024-08-30 |
2024-09-04 |
chicken |
| Laurent Galineau, Emmanuelle Claude, Zuhal Gulhan, Sylvie Bodard, Sophie Sérrière, Camille Dupuy, Jérémy Monteiro, Adeline Oury, Priscila Bertevello, Gabrielle Chicheri, Johnny Vercouillie, Lydie Nadal-Desbarats, Sylvie Chalon, Antoine Lefèvre, Patrick Emon. DESI-TQ-MS imaging for ex vivo brain biodistribution assessment: evaluation of LBT-999, a ligand of the dopamine transporter (DAT). EJNMMI radiopharmacy and chemistry. vol 9. issue 1. 2024-08-27. PMID:39192050. |
desi-tq-ms imaging for ex vivo brain biodistribution assessment: evaluation of lbt-999, a ligand of the dopamine transporter (dat). |
2024-08-27 |
2024-08-30 |
Not clear |
| Seunghyeon Shin, Hyun-Yeol Nam, Keunyoung Kim, Jihyun Kim, Myung Jun Lee, Kyoungjune Pa. Clinical assessment and striatal dopaminergic activity in healthy controls and patients with Parkinson's disease: a Bayesian approach. Annals of nuclear medicine. 2024-08-27. PMID:39190111. |
we aimed to evaluate correlations between striatal dopamine transporter (dat) uptake and clinical assessments in both patients with parkinson's disease (pd) and healthy controls. |
2024-08-27 |
2024-08-30 |
Not clear |
| Alfonso Mata-Bermudez, Ricardo Trejo-Chávez, Marina Martínez-Vargas, Adán Pérez-Arredondo, Maria de Los Ángeles Martínez-Cardenas, Araceli Diaz-Ruiz, Camilo Rios, Luz Navarr. Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176379. |
in this work, we summarize the studies carried out in patients who have suffered tbi and describe alterations in the dopaminergic system, highlighting (1) dysfunction of the dopaminergic neuronal circuits caused by tbi, where modifications are shown in the dopamine transporter (dat) and alterations in the expression of dopamine receptor 2 (d2r) in brain areas with dopaminergic innervation, thus establishing a hypodopaminergic state and (2) variations in the concentration of dopamine and its metabolites in biological fluids of post-tbi patients, such as elevated dopamine (da) and alterations in homovanillic acid (hva). |
2024-08-23 |
2024-08-25 |
Not clear |
| Takato Hiranita, Su-Min Li, Jonathan L Kat. Effects of Dual Inhibition at Dopamine Transporter and σ Receptors in the Discriminative-Stimulus Effects of Cocaine in Male Rats. The Journal of pharmacology and experimental therapeutics. 2024-08-23. PMID:39179413. |
however, σr antagonists when combined with dopamine transporter (dat) inhibitors substantially decrease cocaine self-administration. |
2024-08-23 |
2024-08-27 |
rat |
| Nirosen Vijiaratnam, Christine Girges, Dilan Athauda, Alexa King, Grace Auld, Rachel McComish, Kashfia Chowdhury, Simon Skene, Kate Maclagan, Kallol Ray Chaudhuri, Vincenzo Libri, John Dickson, Thomas Foltyni. Exploring Analysis Approaches for Using the Dopamine Transporter Striatal Binding Ratio in Early- to Mid-Stage Parkinson's Disease Modification Trials. Movement disorders clinical practice. 2024-08-22. PMID:39169806. |
the dopamine transporter striatal binding ratio (dat sbr) has been used as an outcome measure in parkinson's disease (pd) trials of potential disease-modifying therapies; however, both patient characteristics and analysis approach potentially complicate its interpretation. |
2024-08-22 |
2024-08-24 |
Not clear |
| Jacqueline Saenz, Elnaz Khezerlou, Meha Aggarwal, Amina Shaikh, Naga Ganti, Freja Herborg, Ping-Yue Pa. Parkinson's disease gene, Synaptojanin1, dysregulates the surface maintenance of the dopamine transporter. NPJ Parkinson's disease. vol 10. issue 1. 2024-08-08. PMID:39117637. |
we now report a fast depletion of evoked dopamine and impaired maintenance of the axonal dopamine transporter (dat) in the synj1 haploinsufficient (synj1+/-) neurons. |
2024-08-08 |
2024-08-12 |
Not clear |
| Jeppe C Nielsen, Kristine Salomon, Iris E Kalenderoglou, Sarah Bargmeyer, Tillmann Pape, Azadeh Shahsavar, Claus J Lolan. Structure of the human dopamine transporter in complex with cocaine. Nature. 2024-08-07. PMID:39112703. |
the dopamine transporter (dat) is crucial for regulating dopamine signalling and is the prime mediator for the rewarding and addictive effects of cocaine |
2024-08-07 |
2024-08-10 |
human |
| Peng Huang, Zhiting Wan, Shaogang Q. Targeting the RUNX3-miR-186-3p-DAT-IGF1R axis as a therapeutic strategy in a Parkinson's disease model. Journal of translational medicine. vol 22. issue 1. 2024-08-06. PMID:39103832. |
furthermore, the high mir-186-3p expression in pd can be targeted to inhibit the dat expression, resulting in a decrease in the dopamine content of dopaminergic neurons. |
2024-08-06 |
2024-08-08 |
mouse |
| Xiaoyu Zhong, Jisui Li, Xiaohong X. Adolescent exposure to bisphenol-a antagonizes androgen regulation of social behavior in male mice. Neurotoxicology and teratology. 2024-08-03. PMID:39097242. |
in addition, bpa removed down-regulation in the levels of dopamine (da) transporter (dat) and da receptor 1 (dr1) in the nac of tp-gdx mice. |
2024-08-03 |
2024-08-06 |
mouse |
| Ma Chengcheng, An Panpan, Yan Yalong, Su Mingyu, Xu Wei, Chen Jing, Tang Chuanx. GDNF improves the cognitive ability of PD mice by promoting glycosylation and membrane distribution of DAT. Scientific reports. vol 14. issue 1. 2024-08-01. PMID:39090173. |
the regulation of dopamine transporter (dat) is integral to this process. |
2024-08-01 |
2024-08-05 |
mouse |
| Ma Chengcheng, An Panpan, Yan Yalong, Su Mingyu, Xu Wei, Chen Jing, Tang Chuanx. GDNF improves the cognitive ability of PD mice by promoting glycosylation and membrane distribution of DAT. Scientific reports. vol 14. issue 1. 2024-08-01. PMID:39090173. |
additionally, gdnf potentiated the reutilization of neurotransmitters by the pfc presynaptic membrane, boosting the effective release of dopamine following a single electrical stimulation, ultimately ameliorating the cognitive impairments in pd mice.therefore, we propose that gdnf enhances the glycosylation and membrane trafficking of dat by facilitating the re-aggregation of the golgi apparatus, thereby amplifying the utilization of da signals. |
2024-08-01 |
2024-08-05 |
mouse |