| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manuel Glauco Carbone, Icro Maremman. Chronic Cocaine Use and Parkinson's Disease: An Interpretative Model. International journal of environmental research and public health. vol 21. issue 8. 2024-08-29. PMID:39200714. |
according to the 2023 world drug report, 0.4% of the world's population aged 15 to 64 report using cocaine; this number corresponds to approximately 24.6 million cocaine users worldwide and approximately 1 million subjects with cocaine use disorder (cud). |
2024-08-29 |
2024-09-01 |
human |
| Cecilia Nunez, Jin H Yoon, Constanza de Dios, Vincent Dang, Scott D Lane, Jessica N Vincent, Joy M Schmitz, Margaret C Wardl. Undervaluing nondrug rewards or overvaluing cocaine? Cocaine demand relates to cocaine use severity more strongly than anhedonia in individuals with cocaine use disorder. Experimental and clinical psychopharmacology. 2024-08-29. PMID:39207396. |
cocaine use disorder (cud) is a major public health issue, and greater cocaine use severity has been associated with worse treatment retention and outcomes. |
2024-08-29 |
2024-09-04 |
human |
| Daniel J Wood, Jessica L Huebschman, Dalia Martinez, Evgeny Tsvetkov, Kirsten Snyder, Raymond Tjhia, Jaswinder Kumar, Brandon W Hughes, Makoto Taniguchi, Laura N Smith, Christopher W Cowan, Rachel D Penro. The activity-regulated cytoskeleton-associated protein (Arc) functions in a cell type- and sex-specific manner in the adult nucleus accumbens to regulate non-contingent cocaine behaviors. Genes, brain, and behavior. vol 23. issue 4. 2024-08-21. PMID:39164860. |
repeated cocaine use produces adaptations in brain function that contribute to long-lasting behaviors associated with cocaine use disorder (cud). |
2024-08-21 |
2024-08-23 |
mouse |
| Melissa R Schick, Brian D Kiluk, Charla Nich, Donna LaPaglia, Angela M Haen. Measurement invariance of the perceived stress scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. Journal of substance use and addiction treatment. 2024-08-16. PMID:39151798. |
the present study evaluated measurement invariance of the perceived stress scale (pss) across race, sex, and time, examined its association with cocaine use disorder (cud) treatment outcomes, and tested whether associations were moderated by race and/or sex. |
2024-08-16 |
2024-08-20 |
Not clear |
| Roberto J Morales-Silva, Yobet Perez-Perez, John Alvarado-Torres, Nilenid Rivera-Aviles, Genesis Rodriguez-Torres, Ursula Gelpi-Dominguez, Benjamin Dominguez-Padovani, Alexandra Amador-Maldonado, Marian T Sepulveda-Oreng. Sex-Specific Effects of Chronic Stress Prior to Cocaine Exposure on Cue- vs Drug-Induced Relapse after Prolonged Abstiinence. Behavioural brain research. 2024-08-11. PMID:39128627. |
the comorbidity between cocaine use disorder (cud) and trauma/stressor-related disorders suggests a connection between neurophysiological changes induced by stress and those that lead to cocaine use. |
2024-08-11 |
2024-08-14 |
rat |
| Joya Maser, Mary F Morrison, Helene Philogene Khalid, Ronan Cunningham, Daohai Yu, M Ingre Walters, Xiaoning Lu, Nicolas R Bol. Clavulanic Acid-Mediated Increases in Anterior Cingulate Glutamate Levels are Associated With Decreased Cocaine Craving and Brain Network Functional Connectivity Changes. Current therapeutic research, clinical and experimental. vol 101. 2024-07-24. PMID:39045086. |
there is an urgent need for pharmacological treatment for cocaine (coc) use disorder (cud). |
2024-07-24 |
2024-07-26 |
Not clear |
| Chinwe Nwaneshiudu, Kiran Girdhar, Steven P Kleopoulos, John F Fullard, Eduardo R Butelman, Muhammad A Parvaz, Rita Z Goldstein, Nelly Alia-Klein, Panos Rousso. Dynamic alterations in gene co-expression networks and gene-transcript associations characterize co-morbidities in cocaine use disorder. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026764. |
individuals with cocaine use disorder (cud) who attempt abstinence experience craving and relapse, which poses challenges in treatment. |
2024-07-19 |
2024-07-21 |
Not clear |
| Li Yan McCurdy, Elise E DeVito, Jennifer M Loya, Charla Nich, Zu Wei Zhai, Brian D Kiluk, Marc N Potenz. Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. Drug and alcohol dependence reports. vol 11. 2024-07-06. PMID:38966567. |
few studies have investigated changes in brain structure and function associated with recovery from cocaine use disorder (cud), and fewer still have identified brain changes associated with specific cud treatments, which could inform treatment development and optimization. |
2024-07-06 |
2024-07-08 |
Not clear |
| T Lehoux, Antonio Capobianco, Jérôme Lacoste, Sloane Rollier, Yann Mopsus, Manuela Melgire, Flavien Lecuyer, Miguel Gervilla, Luisa Weine. Virtual reality cue-exposure therapy in reducing cocaine craving: the Promoting Innovative COgnitive behavioral therapy for Cocaine use disorder (PICOC) study protocol for a randomized controlled trial. Trials. vol 25. issue 1. 2024-06-28. PMID:38937824. |
cocaine craving is a central symptom of cocaine use disorders (cud). |
2024-06-28 |
2024-06-30 |
Not clear |
| T Lehoux, Antonio Capobianco, Jérôme Lacoste, Sloane Rollier, Yann Mopsus, Manuela Melgire, Flavien Lecuyer, Miguel Gervilla, Luisa Weine. Virtual reality cue-exposure therapy in reducing cocaine craving: the Promoting Innovative COgnitive behavioral therapy for Cocaine use disorder (PICOC) study protocol for a randomized controlled trial. Trials. vol 25. issue 1. 2024-06-28. PMID:38937824. |
the purpose of this study is to evaluate the efficacy and acceptability of vrcet, as a stand-alone and add-on intervention (i.e., combined with cognitive therapy), compared to a picture-based cet (pcet), in reducing self-reported cocaine craving in inpatients hospitalized for cud. |
2024-06-28 |
2024-06-30 |
Not clear |
| Damiano Terenzi, Nicolas Simon, Michael Joe Munyua Gachomba, Jeanne-Laure de Peretti, Bruno Nazarian, Julien Sein, Jean-Luc Anton, Didier Grandjean, Christelle Baunez, Thierry Chaminad. Social context and drug cues modulate inhibitory control in cocaine addiction: involvement of the STN evidenced through functional MRI. Molecular psychiatry. 2024-06-26. PMID:38926543. |
this study investigated the impact of social context and drug cues on brain correlates of inhibitory control in individuals with and without cocaine use disorder (cud) using functional magnetic resonance imaging (fmri). |
2024-06-26 |
2024-06-29 |
human |
| Damiano Terenzi, Nicolas Simon, Michael Joe Munyua Gachomba, Jeanne-Laure de Peretti, Bruno Nazarian, Julien Sein, Jean-Luc Anton, Didier Grandjean, Christelle Baunez, Thierry Chaminad. Social context and drug cues modulate inhibitory control in cocaine addiction: involvement of the STN evidenced through functional MRI. Molecular psychiatry. 2024-06-26. PMID:38926543. |
the results showed that cud participants, while slower at stopping with neutral cues, recovered control level stopping abilities with cocaine cues, while hc did not show any difference. |
2024-06-26 |
2024-06-29 |
human |
| Mia I Allen, Bernard N Johnson, Ashish Kumar, Yixin Su, Sangeeta Singh, Gagan Deep, Michael A Nade. Behavioral and neuronal extracellular vesicle biomarkers associated with nicotine's enhancement of the reinforcing strength of cocaine in female and male monkeys. Addiction neuroscience. vol 11. 2024-06-24. PMID:38911873. |
while the majority of people with cocaine use disorders (cud) also co-use tobacco/nicotine, most preclinical cocaine research does not include nicotine. |
2024-06-24 |
2024-06-26 |
monkey |
| Zhaoyang Cong, Lin Yang, Ziyang Zhao, Guowei Zheng, Cong Bao, Pengfei Zhang, Jun Wang, Weihao Zheng, Zhijun Yao, Bin H. Disrupted dynamic brain functional connectivity in male cocaine use disorder: Hyperconnectivity, strongly-connected state tendency, and links to impulsivity and borderline traits. Journal of psychiatric research. vol 176. 2024-06-18. PMID:38889552. |
cocaine use disorder (cud) is associated with cognitive and emotional impairments, often manifesting as alterations in brain functional connectivity (fc). |
2024-06-18 |
2024-06-21 |
human |
| B Celia Cui, Marina Aksenova, Aliaksandra Sikirzhytskaya, Diana Odhiambo, Elizaveta Korunova, Vitali Sikirzhytski, Hao Ji, Diego Altomare, Eugenia Broude, Norma Frizzell, Rosemarie Booze, Michael D Wyatt, Michael Shtutma. Suppression of HIV-TAT and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters. Journal of neurovirology. 2024-06-17. PMID:38884890. |
there is an urgent need for therapeutic strategies to combat hand comorbid with cocaine use disorder (cud). |
2024-06-17 |
2024-06-19 |
Not clear |
| Leandro F Vendruscolo, Janaina C M Vendruscolo, Kimberly E Whiting, Jane B Acri, Nora D Volkow, George F Koo. The mGlu5 receptor negative allosteric modulator mavoglurant reduces escalated cocaine self-administration in male and female rats. Psychopharmacology. 2024-06-13. PMID:38869515. |
cocaine use disorder (cud) is a brain disorder for which there is no food and drug administration-approved pharmacological treatment. |
2024-06-13 |
2024-06-15 |
rat |
| Joshua N Prete, Miracle A Collier, Phillip M Epperly, Paul W Czot. Effects of self- and experimenter-administered cocaine on subsequent ethanol drinking in rhesus monkeys. Drug and alcohol dependence. vol 260. 2024-06-04. PMID:38833794. |
one possible reason for the lack of fda-approved pharmacotherapies to treat cocaine use disorder (cud) is that, although cocaine is typically used in combination with alcohol, it is studied in isolation in preclinical studies. |
2024-06-04 |
2024-06-07 |
monkey |
| b' Margaux Poireau, Shailendra Segobin, Ang\xe9line Maillard, Virgile Clergue-Duval, Romain Icick, Julien Azuar, Emmanuelle Volle, Christine Delmaire, Vanessa Bloch, Anne-Lise Pitel, Florence Vorspa. Brain alterations in Cocaine Use Disorder: Does the route of use matter and does it relate to the treatment outcome? Psychiatry research. Neuroimaging. vol 342. 2024-05-31. PMID:38820804.' |
cocaine use disorder (cud) is an important health issue, associated with structural brain abnormalities. |
2024-05-31 |
2024-06-02 |
Not clear |
| Margaux Poireau, Virgile Clergue-Duval, Angéline Maillard, Romain Icick, Julien Azuar, Pauline Smith, Mathieu Faurent, Emmanuelle Volle, Christine Delmaire, Julien Cabé, Vanessa Bloch, Florence Vorspa. Predictors of abstinence maintenance after cocaine inpatient detoxification: A prospective study. The American journal on addictions. 2024-05-18. PMID:38761123. |
cocaine is a highly addictive substance, and with no approved medication for cocaine use disorder (cud), leading to a heavy burden. |
2024-05-18 |
2024-05-27 |
Not clear |
| Victoria R Votaw, Felicia R Tuchman, Corey R Roos, Hanna M Hebden, James R McKay, Brian D Kiluk, Katie Witkiewit. Examining cocaine use reductions and long-term outcomes in two clinical trials of continuing care for cocaine dependence. Journal of substance use and addiction treatment. 2024-05-12. PMID:38735481. |
there is a need to identify clinically meaningful non-abstinent endpoints for cocaine use disorder (cud) clinical trials. |
2024-05-12 |
2024-05-27 |
Not clear |