| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oyovwi Mega Obukohwo, Benneth Ben-Azu, Eze Kingsley Nwangwa, Ejiro Peggy Ohwin, John C Igweh, Ezekiel Adeogun Adetomiw. Adverse hematological profiles associated with chlorpromazine antipsychotic treatment in male rats: Preventive and reversal mechanisms of taurine and coenzyme-Q10. Toxicology reports. vol 12. 2024-05-02. PMID:38693965. |
chlorpromazine (cpz) is one of the most effective antipsychotic drugs used for managing psychotic related disorders owing to its dopamine receptor blocking action. |
2024-05-02 |
2024-05-04 |
rat |
| Sara Krawczyk, Sylwia Golba, Cristina Neves, João Tedi. Chlorpromazine-Polypyrrole Drug Delivery System Tailored for Neurological Application. Molecules (Basel, Switzerland). vol 29. issue 7. 2024-04-13. PMID:38611809. |
in this research, a well-known cp, polypyrrole (ppy), was synthesized in the presence of the polysaccharide heparin (hep) and chlorpromazine (cpz) using sodium dodecyl sulfate (sds) as electrolyte on a steel substrate. |
2024-04-13 |
2024-04-15 |
Not clear |
| James Dumba, Antwi Joseph Barimah, Mohammed Mohammed Ibrahim, Solomon Saka Allotey, Semefa Alorvi, William Appertey, Luke Sopaal, Frank Acheampong, Rebecca Dorcas Commey, Yaw Boakye Nketiah, Deborah Ampofo, Bernard Opoku Amoah, Larry Agyeman. Prevalence and prescribers' knowledge of psychotropic polypharmacy in the Bono, Bono East, and Ahafo Regions, Ghana. Heliyon. vol 10. issue 2. 2024-01-31. PMID:38293502. |
psychotropic polypharmacy was prevalent (66.0 %) in the study area with antipsychotic polypharmacy (74.0 %) being the common form with the co-prescription of chlorpromazine (cpz) + haloperidol (70.0 %) being frequent. |
2024-01-31 |
2024-02-02 |
Not clear |
| Mohammad K Hammood, Jalal N Jeber, Maryam A Khalaf, Haneen Abdul Hadi Kharab. Rapid colorimetric sensing of chlorpromazine HCl antipsychotic through RSC advances. vol 14. issue 4. 2024-01-12. PMID:38213959. |
rapid colorimetric sensing of chlorpromazine hcl antipsychotic through antipsychotic drugs like chlorpromazine hydrochloride (cpz) are widely used to treat mental illnesses but can accumulate in the environment if not properly disposed of. |
2024-01-12 |
2024-01-14 |
Not clear |
| Mohammad K Hammood, Jalal N Jeber, Maryam A Khalaf, Haneen Abdul Hadi Kharab. Rapid colorimetric sensing of chlorpromazine HCl antipsychotic through RSC advances. vol 14. issue 4. 2024-01-12. PMID:38213959. |
this study reports a colorimetric assay for detection of the antipsychotic drug chlorpromazine hydrochloride (cpz) based on its ability to reduce gold ions and form gold nanoparticles (aunps). |
2024-01-12 |
2024-01-14 |
Not clear |
| Federica Impellitteri, Katerina Yunko, Giovanna Calabrese, Miriam Porretti, Viktoria Martyniuk, Lesya Gnatyshyna, Vincenzo Nava, Angela Giorgia Potortì, Giuseppe Piccione, Giuseppa Di Bella, Oksana Stoliar, Caterina Faggi. Chlorpromazine's impact on Mytilus galloprovincialis: A multi-faceted investigation. Chemosphere. 2023-12-31. PMID:38160957. |
the antipsychotic chlorpromazine (cpz) has raised concern as a pharmaceutical effluent due to its wide medical applications. |
2023-12-31 |
2024-01-05 |
Not clear |
| Claudia Abbruzzese, Silvia Matteoni, Paola Matarrese, Michele Signore, Barbara Ascione, Elisabetta Iessi, Aymone Gurtner, Andrea Sacconi, Lucia Ricci-Vitiani, Roberto Pallini, Andrea Pace, Veronica Villani, Andrea Polo, Susan Costantini, Alfredo Budillon, Gennaro Ciliberto, Marco G Pagg. Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2. Cell death & disease. vol 14. issue 12. 2023-12-13. PMID:38092755. |
in our attempts to identify repositionable drugs in glioblastoma therapy, we identified the neuroleptic drug chlorpromazine (cpz) as a very promising compound. |
2023-12-13 |
2023-12-17 |
Not clear |
| Junhee Lee, Sanghoon Oh, Sun-Young Moon, Silvia Kyungjin Loh, Minah Kim, Tae Young Lee, Jun Soo Kwo. Impact of long-acting injectable aripiprazole on the concomitant medication and antipsychotic polypharmacy: a retrospective, observational study of 127 patients with psychosis. International clinical psychopharmacology. 2023-11-20. PMID:37982292. |
daily chlorpromazine equivalent (cpz) dose of aps decreased from 124.40 ± 235.35 mg to 77.95 ± 210.36 mg (p = 0.027). |
2023-11-20 |
2023-11-29 |
Not clear |
| Ningning Li, Lingling Rao, Xueqing Zhao, Junwen Shen, Dan Su, Guoqiang Ma, Shan Sun, Qilian Ma, Li Zhang, Chunsheng Dong, Kin Yip Tam, Jochen H M Prehn, Hongfeng Wang, Zheng Yin. Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling. Frontiers in cell and developmental biology. vol 11. 2023-09-25. PMID:37745295. |
according to the previous studies, chlorpromazine (cpz), an fda-approved antipsychotic drug, affects autophagy in diverse cell lines, but the underlying mechanism remains elusive. |
2023-09-25 |
2023-10-07 |
human |
| Xuemei Xian, Sheng Yang, Yonghong Shi, Qiusheng Che. Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts. Poultry science. vol 102. issue 9. 2023-07-16. PMID:37454644. |
dtmuv entry into bhk-21 and def cells was blocked by clathrin inhibitor, chlorpromazine (cpz), indicating that the flavivirus dtmuv enters bhk-21 and def both via a clathrin-mediated endocytosis (cme) pathway rather than caveola-mediated endocytosis or micropinocytosis. |
2023-07-16 |
2023-08-14 |
Not clear |
| Haoxiang Guo, Huan Yu, He Zu, Jinbin Cui, Heng Ding, Yanan Xia, Dandan Chen, Yuan Zeng, Yangyun Wang, Yong Wang, Leshuai W Zhan. Mechanistic Study for Drug Induced Cholestasis Using Batch-Fabricated 3D Spheroids Developed by Agarose-Stamping Method. Toxicology letters. 2023-06-16. PMID:37327977. |
chlorpromazine (cpz) was used as a model drug to investigate the mechanism for drug induced cholestasis (dic) by agarose-stamping method. |
2023-06-16 |
2023-08-14 |
rat |
| Thinh To Quoc, Krisztina Bíró, Ágota Pető, Dóra Kósa, Dávid Sinka, István Lekli, Attila Kiss-Szikszai, István Budai, Mónika Béres, Miklós Vecsernyés, Pálma Fehér, Ildikó Bácskay, Zoltán Ujhely. Development and Evaluation of an FDM Printed Nasal Device for CPZ Solid Nanoparticles. Molecules (Basel, Switzerland). vol 28. issue 11. 2023-06-11. PMID:37298882. |
we used chlorpromazine (cpz), which is mainly used in the treatment of psychotic disorders such as schizophrenia and bipolar disorder. |
2023-06-11 |
2023-08-14 |
Not clear |
| Yvonne Kohl, Nicola William, Elisabeth Elje, Nadine Backes, Mario Rothbauer, Annamaria Srancikova, Elise Rundén-Pran, Naouale El Yamani, Rafi Korenstein, Lea Madi, Alexander Barbul, Katarina Kozics, Monika Sramkova, Karen Steenson, Alena Gabelova, Peter Ertl, Maria Dusinska, Andrew Nelso. Rapid identification of in vitro cell toxicity using an electrochemical membrane screening platform. Bioelectrochemistry (Amsterdam, Netherlands). vol 153. 2023-05-27. PMID:37244203. |
this study compares the performance and output of an electrochemical phospholipid membrane platform against respective in vitro cell-based toxicity testing methods using three toxicants of different biological action (chlorpromazine (cpz), colchicine (col) and methyl methanesulphonate (mms)). |
2023-05-27 |
2023-08-14 |
human |
| b' Jiandan Chen, Hongying Liu, Chenwei Wang, Kai Fan, Lihua Li, Yuqing Zhang, Lu Fang, Zheng-Zhi Yin, Zhong L\\xc3\\xb. An electrochemical chlorpromazine sensor based on a gold-copper bimetallic synergetic molecularly imprinted interface on an acupuncture needle electrode. The Analyst. 2023-04-28. PMID:37114554.' |
chlorpromazine (cpz) is a medicine for nervous system disorders. |
2023-04-28 |
2023-08-14 |
Not clear |
| Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu, Amit Awasthi, Krishnan H Harshan, Sanjeev Jain, Shantanu Chowdhur. G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters. Frontiers in molecular biosciences. vol 10. 2023-04-03. PMID:37006620. |
the g4 structure was targeted using fda-approved drugs that can bind g4s - chlorpromazine (cpz) and prochlorperazine (pcz). |
2023-04-03 |
2023-08-14 |
Not clear |
| Ruijue Chen, Qiying Chen, Ying Wang, Zhiyang Feng, ZiWei Xu, Pei Zhou, Wenyi Huang, Hao Cheng, Lijun Li, Jun Fen. Ultrasensitive SERS substrate for label-free therapeutic drug monitoring of chlorpromazine hydrochloride and aminophylline in human serum. Analytical and bioanalytical chemistry. 2023-03-17. PMID:36928580. |
owing to the large specific surface area and ultra-high porosity of mil-101(cr)@ag, we developed a method for the determination of chlorpromazine hydrochloride (cpz) and aminophylline (amp) in human serum by using it as a solid-phase extraction sorbent and sers substrate. |
2023-03-17 |
2023-08-14 |
human |
| Tian Qishuo, Zhang Youyou, Zhang Jie, Yu Yalei, Zhang Wei, Liu Quan, Liu Liang, Ren Lian. Role of the heat shock protein family in chlorpromazine-induced cardiotoxicity. Journal of applied toxicology : JAT. 2023-02-08. PMID:36751017. |
chlorpromazine (cpz), a first-generation antipsychotic, is widely used in treating schizophrenia and other psychiatric disorders. |
2023-02-08 |
2023-08-14 |
rat |
| Clara Inés McCarthy, Emilio Román Mustafá, María Paula Cornejo, Agustín Yaneff, Silvia Susana Rodríguez, Mario Perello, Jesica Raing. Chlorpromazine, an Inverse Agonist of D1R-Like, Differentially Targets Voltage-Gated Calcium Channel (Ca Molecular neurobiology. 2023-01-24. PMID:36694048. |
here, we studied the impact of d1r-like constitutive activity and chlorpromazine (cpz), an antipsychotic drug and d1r-like inverse agonist, on various neuronal ca |
2023-01-24 |
2023-08-14 |
Not clear |
| Rui Bai, Xiaohui Dai, Xingang Miao, Bing Xie, Feng Yu, Bin Cong, Di Wen, Chunling M. Dynamic Changes in Plasma Metabolic Profiles Reveal a Potential Metabolite Panel for Interpretation of Fatal Intoxication by Chlorpromazine or Olanzapine in Mice. Metabolites. vol 12. issue 12. 2022-12-23. PMID:36557223. |
we used liquid chromatography-mass spectrometry-based integrated metabolomics analysis to measure changes in metabolic profiles in the plasma of mice that died from fatal intoxication due to chlorpromazine (cpz) or olanzapine (ola). |
2022-12-23 |
2023-08-14 |
mouse |
| Sen Feng, Yongzhi Zhang, Fan Gao, Meng Li, Lingyun Zhu, Hao Wen, Yilong Xi, Xianling Xian. Inhibitory Effects of Antipsychotic Chlorpromazine on the Survival, Reproduction and Population Growth Other Than Neurotransmitters of Zooplankton in Light of Global Warming. International journal of environmental research and public health. vol 19. issue 23. 2022-12-11. PMID:36498239. |
however, little information is available on the effects of antipsychotic drugs commonly used to treat psychosis, such as chlorpromazine (cpz), on non-target aquatic organisms in light of global warming. |
2022-12-11 |
2023-08-14 |
Not clear |