| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minli Zhao, Qiuping Zhang, Yuan Lin, Yukun Chen, Hua Ca. Impact of nitric oxide via cardiopulmonary bypass on pediatric heart surgery: a meta-analysis of randomized controlled trials. Journal of cardiothoracic surgery. vol 19. issue 1. 2024-07-20. PMID:39030578. |
the impact of nitric oxide (no) administered via cardiopulmonary bypass (cpb) on pediatric heart surgery remains controversial. |
2024-07-20 |
2024-07-22 |
Not clear |
| Nikolay O Kamenshchikov, Mariia L Diakova, Yuri K Podoksenov, Elena A Churilina, Tatiana Yu Rebrova, Shamil D Akhmedov, Leonid N Maslov, Alexander V Mukhomedzyanov, Elena B Kim, Ekaterina S Tokareva, Igor V Kravchenko, Alexander M Boiko, Maxim S Kozulin, Boris N Kozlo. Potential Mechanisms for Organoprotective Effects of Exogenous Nitric Oxide in an Experimental Study. Biomedicines. vol 12. issue 4. 2024-04-27. PMID:38672075. |
performing cardiac surgery under cardiopulmonary bypass (cpb) and circulatory arrest (ca) provokes the development of complications caused by tissue metabolism, microcirculatory disorders, and endogenous nitric oxide (no) deficiency. |
2024-04-27 |
2024-04-29 |
Not clear |
| Yun Yan, Nikolay Kamenshchikov, Ziyu Zheng, Chong Le. Inhaled nitric oxide and postoperative outcomes in cardiac surgery during cardiopulmonary bypass: A systematic review and meta-analysis. Nitric oxide : biology and chemistry. 2024-03-31. PMID:38556145. |
the inhaled nitric oxide (ino) has been frequently used as an important composite of perioperative management during cardiac surgery under cpb. |
2024-03-31 |
2024-04-03 |
Not clear |
| Emanuele Rezoagli, Simone Redaelli, Edward A Bittner, Roberto Fumagalli, Fumito Ichinose, Lorenzo Berr. Role of hemolysis on pulmonary arterial compliance and right ventricular systolic function after cardiopulmonary bypass. Nitric oxide : biology and chemistry. 2024-03-23. PMID:38521488. |
cardiopulmonary bypass (cpb) is associated with intravascular hemolysis which depletes endogenous nitric oxide (no). |
2024-03-23 |
2024-03-26 |
Not clear |
| Divya A Khandekar, Troy G Seelhammer, Kristin C Mara, Elizabeth H Stephens, Erica D Wittwer, Patrick M Wieruszewsk. Intraoperative Versus Postoperative Hydroxocobalamin for Vasoplegic Shock in Cardiothoracic Surgery. Journal of cardiothoracic and vascular anesthesia. 2023-09-18. PMID:37723020. |
hydroxocobalamin inhibits nitric oxide pathways contributing to vasoplegic shock in patients undergoing cardiopulmonary bypass (cpb). |
2023-09-18 |
2023-10-07 |
Not clear |
| Fei Xu, Weina L. Delivery exogenous nitric oxide via cardiopulmonary bypass in pediatric cardiac surgery reduces the duration of postoperative mechanical ventilation-A meta-analysis of randomized controlled trials. Heliyon. vol 9. issue 8. 2023-08-28. PMID:37636442. |
the aim of this study is to summarize the available evidence and evaluate whether exogenous nitric oxide administered via cpb circuits can improve recovery after cardiac surgery in children. |
2023-08-28 |
2023-09-07 |
Not clear |
| Walaa Elnaiem, Abdulhay Mohamed Elnour, Abubaker E A Koko, Maysa Madany, Lina Hemmed. Efficacy and safety of inhaled nitric oxide administered during cardiopulmonary bypass for pediatric cardiac surgery: a systematic review and meta-analysis. Annals of medicine and surgery (2012). vol 85. issue 6. 2023-06-27. PMID:37363460. |
the benefits of incorporating nitric oxide (no) into the cpb circuit have been reported in terms of reduced inflammation, enhanced dynamic circulation, oxygenation, and end-organ function. |
2023-06-27 |
2023-08-14 |
Not clear |
| Jason W Greenberg, Spencer Hogue, Muhammad Aanish Raees, Hosam F Ahmed, William A Abplanalp, Amalia Guzman-Gomez, Zakia Abdelhamed, Karthik Thangappan, James A Reagor, James E Rose, Michaela Collins, Jennifer L Kasten, Stuart L Goldstein, Farhan Zafar, David L S Morales, David S Coope. Exogenous Nitric Oxide Delivery Protects Against Cardiopulmonary Bypass-Associated Acute Kidney Injury: Histologic and Serologic Evidence from an Ovine Model. The Journal of thoracic and cardiovascular surgery. 2023-05-10. PMID:37164051. |
several human studies have associated nitric oxide (no) administration via the cardiopulmonary bypass-(cpb) circuit with decreased incidence of cpb-associated acute kidney injury-(aki), but histopathologic and serologic evidence of no efficacy for aki attenuation are lacking. |
2023-05-10 |
2023-08-14 |
human |
| Zied Ltaief, Nawfel Ben-Hamouda, Valentina Rancati, Ziyad Gunga, Carlo Marcucci, Matthias Kirsch, Lucas Liaude. Vasoplegic Syndrome after Cardiopulmonary Bypass in Cardiovascular Surgery: Pathophysiology and Management in Critical Care. Journal of clinical medicine. vol 11. issue 21. 2022-11-11. PMID:36362635. |
surgical trauma, exposure to the elements of the cpb circuit and ischemia-reperfusion promote a systemic inflammatory response with the release of cytokines (il-1β, il-6, il-8, and tnf-α) with vasodilating properties, both direct and indirect through the expression of inducible nitric oxide (no) synthase. |
2022-11-11 |
2023-08-14 |
Not clear |
| Jacek Kolcz, Elzbieta Karnas, Zbigniew Madeja, Ewa K Zuba-Surm. The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study. Journal of intensive care. vol 10. issue 1. 2022-10-13. PMID:36229863. |
this study investigated the influence of inhaled nitric oxide (no) during cpb on early clinical results, including the duration of postoperative respiratory support as a primary outcome and a panel of laboratory analytes. |
2022-10-13 |
2023-08-14 |
Not clear |
| Leandro da Costa Clementino, Guilherme Felipe Santos Fernandes, Igor Muccilo Prokopczyk, Wilquer Castro Laurindo, Danyelle Toyama, Bruno Pereira Motta, Amanda Martins Baviera, Flávio Henrique-Silva, Jean Leandro Dos Santos, Marcia A S Graminh. Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity. PloS one. vol 16. issue 11. 2021-11-05. PMID:34723989. |
in vitro studies suggested that 4f may act by a dual effect, by releasing nitric oxide after biotransformation and by inhibiting cysteine protease cpb (ic50: 4.5 μm). |
2021-11-05 |
2023-08-13 |
mouse |
| Robert A Niebler, Huang Chiang-Ching, Kevin Daley, Rae Janecke, Shawn M Jobe, Michael E Mitchell, Caleb Varner, Katherine Woods, John P Scot. Nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass in infants: A pilot randomized controlled trial. Artificial organs. vol 45. issue 1. 2021-09-27. PMID:32737900. |
our objective was to assess the effect of nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass (cpb) in infants on platelet count, platelet function, clinical outcomes, and safety. |
2021-09-27 |
2023-08-13 |
Not clear |
| Robert A Niebler, Huang Chiang-Ching, Kevin Daley, Rae Janecke, Shawn M Jobe, Michael E Mitchell, Caleb Varner, Katherine Woods, John P Scot. Nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass in infants: A pilot randomized controlled trial. Artificial organs. vol 45. issue 1. 2021-09-27. PMID:32737900. |
nitric oxide added to the sweep gas of the oxygenator during cpb in infants did not have an appreciable effect on the preservation of platelet count, platelet responsiveness to agonist, or clinical outcomes. |
2021-09-27 |
2023-08-13 |
Not clear |
| Jerry J Markar, Andrew A Disqu. Ventilator Failure Following Cardiopulmonary Bypass: A Case Report. A&A practice. vol 14. issue 10. 2021-07-28. PMID:32739985. |
we present 3 cardiothoracic surgery cases during which the drager perseus a500 anesthesia machine and the inomax delivery system were used concurrently, resulting in ventilator failures while attempting to separate from cardiopulmonary bypass (cpb). |
2021-07-28 |
2023-08-13 |
Not clear |
| Vincent Peyko, Michael Finamor. Use of Intravenous Hydroxocobalamin without Methylene Blue for Refractory Vasoplegic Syndrome After Cardiopulmonary Bypass. The American journal of case reports. vol 22. 2021-06-22. PMID:34143764. |
vasoplegic syndrome after cpb that is refractory to other vasopressors, such as catecholamine and vasopressin, has been successfully treated with inhibitors of the nitric oxide (no) system, such as methylene blue and hydroxocobalamin. |
2021-06-22 |
2023-08-13 |
Not clear |
| Joseph Mc Loughlin, Lorraine Browne, John Hinchio. The impact of exogenous nitric oxide during cardiopulmonary bypass for cardiac surgery. Perfusion. 2021-05-13. PMID:33983090. |
this study is a systematic review of the impact of gaseous nitric oxide (gno), delivered via the cardiopulmonary bypass (cpb) circuit during cardiac surgery, on post-operative outcomes. |
2021-05-13 |
2023-08-13 |
Not clear |
| Luregn J Schlapbach, Stephen Brian Horton, Debbie Amanda Long, John Beca, Simon Erickson, Marino Festa, Yves d'Udekem, Nelson Alphonso, David Winlaw, Kerry Johnson, Carmel Delzoppo, Kim van Loon, B Gannon, Jonas Fooken, Antje Blumenthal, Paul Young, Mark Jones, Warwick Butt, Andreas Schible. Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial. BMJ open. vol 9. issue 8. 2020-08-27. PMID:31420383. |
delivery of nitric oxide (no) into cpb circuits can provide myocardial protection and reduce bypass-induced inflammation, leading to less lcos and improved recovery. |
2020-08-27 |
2023-08-13 |
Not clear |
| Qinghong Li, Dorothy P Laflamme, John E Baue. Serum untargeted metabolomic changes in response to diet intervention in dogs with preclinical myxomatous mitral valve disease. PloS one. vol 15. issue 6. 2020-08-24. PMID:32555688. |
arginine and citrulline, precursors of nitric oxide biosynthesis, were both increased 2-fold; caprate, a medium chain fa, was increased 3-fold; and deoxycarnitine, precursor of carnitine biosynthesis, was increased 2.5-fold in cpb dogs. |
2020-08-24 |
2023-08-13 |
Not clear |
| Nikolay O Kamenshchikov, Yana J Anfinogenova, Boris N Kozlov, Yulia S Svirko, Stanislav E Pekarskiy, Vladimir V Evtushenko, Vladimir A Lugovsky, Vladimir M Shipulin, Vladimir V Lomivorotov, Yuriy K Podokseno. Nitric oxide delivery during cardiopulmonary bypass reduces acute kidney injury: A randomized trial. The Journal of thoracic and cardiovascular surgery. 2020-07-28. PMID:32718702. |
the aim of this study was to evaluate the effects of nitric oxide (no) supplementation to the cpb circuit on the development of cardiac surgery-associated aki. |
2020-07-28 |
2023-08-13 |
Not clear |
| Nikolay O Kamenshchikov, Irina A Mandel, Yuriy K Podoksenov, Yulia S Svirko, Vladimir V Lomivorotov, Sergey L Mikheev, Boris N Kozlov, Vladimir M Shipulin, Aleksandra A Nenakhova, Yana J Anfinogenov. Nitric oxide provides myocardial protection when added to the cardiopulmonary bypass circuit during cardiac surgery: Randomized trial. The Journal of thoracic and cardiovascular surgery. vol 157. issue 6. 2020-02-24. PMID:30447958. |
the aim of this pilot study was to elucidate the effects of exogenous nitric oxide (no) supply to the extracorporeal circulation circuit for cardioprotection against ischemia-reperfusion injury during coronary artery bypass grafting (cabg) with cardiopulmonary bypass (cpb). |
2020-02-24 |
2023-08-13 |
Not clear |