All Relations between cox and aspartate

Publication Sentence Publish Date Extraction Date Species
Mohammad Dehghani Firouzabadi, Amirhossein Poopak, Ali Sheikhy, Fatemeh Dehghani Firouzabadi, Fatemeh Moosaie, Soghra Rabizadeh, Sara Momtazmanesh, Manouchehr Nakhjavani, Alireza Esteghamat. Nonalcoholic Fatty Liver Disease as a Potential Risk Factor for Cardiovascular Disease in Patients with Type 2 Diabetes: A Prospective Cohort Study. International journal of endocrinology. vol 2024. 2024-07-04. PMID:38962375. cox regression analysis was used to assess the association between nafld, liver enzyme level, aspartate aminotransferase to platelet ratio index (apri), and the incidence risk of cvd and its subgroups (i.e., myocardial infarction, chronic heart disease, coronary artery bypass grafting, and percutaneous coronary intervention). 2024-07-04 2024-07-10 Not clear
KyoungSoo Lim, Aburough Abegesah, Chunling Fan, Jimmy Zhijian He, Xuyang Song, Cecil Chen, Alejandra Negro, Mallory Makowsky, Charu Gupta, Song Ren, Alex Phipps, Megan Gibbs, Diansong Zho. Population Pharmacokinetics and Exposure-Response Analysis of Tremelimumab 300 Mg Single Dose Combined With Durvalumab 1,500 Mg Q4w (Stride) in Patients With Unresectable Hepatocellular Carcinoma. Journal of clinical pharmacology. 2023-06-10. PMID:37300457. baseline aspartate aminotransferase and neutrophil-to-lymphocyte ratio were associated with overall survival (p < 0.001) by cox proportional hazards model. 2023-06-10 2023-08-14 Not clear
Oana Albai, Mirela Frandes, Alexandra Sima, Bogdan Timar, Adrian Vlad, Romulus Tima. Practical Applicability of the ISARIC-4C Score on Severity and Mortality due to SARS-CoV-2 Infection in Patients with Type 2 Diabetes. Medicina (Kaunas, Lithuania). vol 58. issue 7. 2022-07-28. PMID:35888567. the cox regression model showed that the length of hospitalization (lh) was significantly influenced by body mass index, lung impairment, and aspartate aminotransferase, increasing the hazards, while lower hba1c and lower sato2 significantly decreased the hazards. 2022-07-28 2023-08-16 Not clear
Sabreen E Fadl, Zizy I Elbialy, Walied Abdo, Adel Hassan Saad, Mohamed Aboubakr, Ahmed Abdeen, Mohamed Morsi Elkamshishi, Abdallah S Salah, Amany El-Mleeh, Rafa Almeer, Lotfi Aleya, Mohamed M Abdel-Daim, Agnieszka Najda, Ehab Yahya Abdelhie. Ameliorative effect of Spirulina and Saccharomyces cerevisiae against fipronil toxicity in Oreochromis niloticus. Ecotoxicology and environmental safety. vol 242. 2022-07-23. PMID:35870348. fipronil is a kind of pesticide that is widely used in agriculture, thus this trial was conducted to evaluate the effect of fipronil on growth related parameters (final body weight, feed intake, weight gain, feed conversion ratio, specific growth rate, and protein efficiency ratio), hematology related parameters (rbcs, wbcs, hemoglobin, packed cell volume, and deferential leukocytic count), biochemistry related parameters (alanine aminotransferase, aspartate aminotransferase, total protein, albumin, urea, and creatinine), histopathology of liver, intestine, gills, and spleen, and gene expression of antioxidants, stress, inflammatory, apoptotic, and related to junction proteins genes as sod and gpx, cox ii, tnf-α, casp-3, and claudin-3, respectively, in nile tilapia (oreochromis niloticus). 2022-07-23 2023-08-14 Not clear
Jinsoo Rhu, Jong Man Kim, Kyunga Kim, Heejin Yoo, Gyu-Seong Choi, Jae-Won Jo. Prediction model for early graft failure after liver transplantation using aspartate aminotransferase, total bilirubin and coagulation factor. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34145352. cox regression model for predicting early graft failure after liver transplantation using post-transplantation aspartate aminotransferase, total bilirubin, and international normalized ratio of prothrombin time was constructed based on data from both living donor (n = 1153) and deceased donor (n = 359) liver transplantation performed during 2004 to 2018. 2021-11-05 2023-08-13 Not clear
Tak Kyu Oh, Eun Sun Jang, In-Ae Son. Long-term mortality due to infection associated with elevated liver enzymes: a population-based cohort study. Scientific reports. vol 11. issue 1. 2021-11-01. PMID:34127778. aspartate transaminase (ast), alanine aminotransferase (alt), γ-glutamyl transpeptidase (γ-gtp), ast/alt ratio, and dynamic ast/alt ratio (daar) were included in multivariable cox modeling. 2021-11-01 2023-08-13 Not clear
Giovanni Marasco, Francesco Poggioli, Antonio Colecchia, Giuseppe Cabibbo, Filippo Pelizzaro, Edoardo Giovanni Giannini, Sara Marinelli, Gian Ludovico Rapaccini, Eugenio Caturelli, Mariella Di Marco, Elisabetta Biasini, Fabio Marra, Filomena Morisco, Francesco Giuseppe Foschi, Marco Zoli, Antonio Gasbarrini, Gianluca Svegliati Baroni, Alberto Masotto, Rodolfo Sacco, Giovanni Raimondo, Francesco Azzaroli, Andrea Mega, Gianpaolo Vidili, Maurizia Rossana Brunetto, Gerardo Nardone, Luigina Vanessa Alemanni, Elton Dajti, Federico Ravaioli, Davide Festi, Franco Trevisani, On Behalf Of The Italian Liver Cancer Ita Li Ca Grou. A Nomogram-Based Prognostic Model for Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib: A Multicenter Study. Cancers. vol 13. issue 11. 2021-06-15. PMID:34072309. the eastern cooperative oncology group (ecog) performance status (ps) (hazard ratio (hr) 1.284), maximum tumoral diameter (hr 1.100), plasma total bilirubin (hr 1.119), aspartate amino transferase assessed as multiple of the upper normal value (hr 1.032), alpha-fetoprotein ≥200 ng/ml (hr 1.342), hemoglobin (hr 0.903) and platelet count (hr 1.002) were associated with os at multivariate cox regression analysis. 2021-06-15 2023-08-13 Not clear
Jiandong Zhou, Sharen Lee, Xiansong Wang, Yi Li, William Ka Kei Wu, Tong Liu, Zhidong Cao, Daniel Dajun Zeng, Keith Sai Kit Leung, Abraham Ka Chung Wai, Ian Chi Kei Wong, Bernard Man Yung Cheung, Qingpeng Zhang, Gary Ts. Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong. NPJ digital medicine. vol 4. issue 1. 2021-04-29. PMID:33833388. a risk score including the following components was derived from cox regression: gender, age, diabetes mellitus, hypertension, atrial fibrillation, heart failure, ischemic heart disease, peripheral vascular disease, stroke, dementia, liver diseases, gastrointestinal bleeding, cancer, increases in neutrophil count, potassium, urea, creatinine, aspartate transaminase, alanine transaminase, bilirubin, d-dimer, high sensitive troponin-i, lactate dehydrogenase, activated partial thromboplastin time, prothrombin time, and c-reactive protein, as well as decreases in lymphocyte count, platelet, hematocrit, albumin, sodium, low-density lipoprotein, high-density lipoprotein, cholesterol, glucose, and base excess. 2021-04-29 2023-08-13 Not clear
Xiaoting Wu, Mengli Chen, Kai Wang, Rongrong Gao, Xinli L. Gender Differences in Prognostic Markers of All-Cause Death in Patients with Acute Heart Failure: a Prospective 18-Month Follow-Up Study. Journal of cardiovascular translational research. vol 13. issue 1. 2020-09-14. PMID:31119563. based on multiple cox stepwise regression and roc curve analysis, diastolic blood pressure (dbp), serum sodium, serum creatinine, and pulmonary artery systolic pressure (pasp) were identified as independent predictors of all-cause death in male ahf patients, while systolic blood pressure (sbp), serum aspartate transaminase (ast), serum creatinine, and serum d-dimer as independent predictors in females. 2020-09-14 2023-08-13 Not clear
Zhenyin Liu, Jing Zhan. Age, choline-to-N-acetyl aspartate, and lipids-lactate-to-creatine ratios assemble a significant Cox's proportional-hazards regression model for survival prediction in patients with high-grade gliomas. The British journal of radiology. vol 90. issue 1075. 2018-10-30. PMID:28508689. age, choline-to-n-acetyl aspartate, and lipids-lactate-to-creatine ratios assemble a significant cox's proportional-hazards regression model for survival prediction in patients with high-grade gliomas. 2018-10-30 2023-08-13 Not clear
Tsung-Ming Chen, Chun-Che Lin, Pi-Teh Huang, Chen-Fan We. High post-treatment absolute monocyte count predicted hepatocellular carcinoma risk in HCV patients who failed peginterferon/ribavirin therapy. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 6. 2017-02-07. PMID:26662957. cox regression analysis revealed that post-treatment afp level (hr 1.070; 95 % ci = 1.024-1.119, p = 0.003) and post-treatment aspartate aminotransferase (ast)-to-platelet ratio index (apri) ≥0.5 (hr 4.401; 95 % ci = 1.463-13.233, p = 0.008) were independent variables associated with hcc development for svr patients. 2017-02-07 2023-08-13 Not clear
Ernesto Roldan-Valadez, Camilo Rios, Daniel Motola-Kuba, Juan Matus-Santos, Antonio R Villa, Sergio Moreno-Jimene. Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas. The British journal of radiology. vol 89. issue 1067. 2017-01-30. PMID:27626830. choline-to-n-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant cox's proportional-hazards regression model for prediction of survival in high-grade gliomas. 2017-01-30 2023-08-13 Not clear
Chi-Lung Tseng, Wei-Jen Lai, Chun-Jui Huang, Yi-Hsiang Huang, Chien-Wei Su, I-Cheng Lee, Hsiou-Shan Tseng, Chung-Pin Li, Rheun-Chuan Lee, Han-Chieh Lin, Yee Cha. The Effectiveness of ART Score in Selecting Patients for Transarterial Chemoembolization Retreatment: A Cohort Study in Taiwan. Medicine. vol 94. issue 47. 2016-04-07. PMID:26632677. multivariate cox regression analysis revealed that tumor size >7.2 cm (hazard ratio 4.44, p < 0.001), aspartate transaminase (ast) level above 95 iu/l (hazard ratio 2.18, p = 0.02), ast increase more than 25% (hazard ratio 2.13, p = 0.02), 2nd/1st (pre-tace) alpha-fetoprotein ratio (hazard ratio 1.40, p = 0.001), and lack of radiological response to tace (hazard ratio 2.21, p = 0.02) were independent clinical determinants of survival. 2016-04-07 2023-08-13 Not clear
Vincent Lo Re, Michael J Kallan, Janet P Tate, Joseph K Lim, Matthew Bidwell Goetz, Marina B Klein, David Rimland, Maria C Rodriguez-Barradas, Adeel A Butt, Cynthia L Gibert, Sheldon T Brown, Lesley S Park, Robert Dubrow, K Rajender Reddy, Jay R Kostman, Amy C Justice, A Russell Locali. Predicting Risk of End-Stage Liver Disease in Antiretroviral-Treated Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Patients. Open forum infectious diseases. vol 2. issue 3. 2015-08-18. PMID:26284259. cox regression was used to develop prognostic models based on baseline demographic, clinical, and laboratory variables, including fib-4 and aspartate aminotransferase-to-platelet ratio index, previously validated markers of hepatic fibrosis. 2015-08-18 2023-08-13 human
Meejung Ahn, Jong Sang Park, Sungwook Chae, Seungjoon Kim, Changjong Moon, Jin Won Hyun, Taekyun Shi. Hepatoprotective effects of Lycium chinense Miller fruit and its constituent betaine in CCl4-induced hepatic damage in rats. Acta histochemica. vol 116. issue 6. 2015-04-20. PMID:24998029. the treatment of lc fruit extract significantly suppressed the increase of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the sera of ccl4 injured rats, and restored the decreased levels of anti-oxidant enzymes such as total antioxidant capacity (tac), superoxide dismutase (sod), catalase (cat) and glutathione peroxidase (gpx) and suppressed the expression of inflammatory mediators including inducible nitric oxide synthase (inos) and cyclooxygenase (cox)-1 and -2. 2015-04-20 2023-08-13 rat
Moritz F Sinner, Na Wang, Caroline S Fox, João D Fontes, Michiel Rienstra, Jared W Magnani, Ramachandran S Vasan, Audrey H Calderwood, Michael Pencina, Lisa M Sullivan, Patrick T Ellinor, Emelia J Benjami. Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation. The American journal of cardiology. vol 111. issue 2. 2013-02-26. PMID:23127690. cox proportional-hazards models adjusted for standard af risk factors (age, gender, body mass index, systolic blood pressure, electrocardiographic pr interval, antihypertensive treatment, smoking, diabetes, valvular heart disease, and alcohol consumption) were examined to investigate associations between baseline serum transaminase levels (alanine transaminase and aspartate transaminase) and the incidence of af over up to 10 years (29,099 person-years) of follow-up. 2013-02-26 2023-08-12 human
Aldo J Montano-Loza, Andrew L Mason, Mang Ma, Ravin J Bastiampillai, Vincent G Bain, Puneeta Tando. Risk factors for recurrence of autoimmune hepatitis after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 15. issue 10. 2009-12-17. PMID:19790153. by univariate cox analysis, the features before liver transplantation associated with a higher risk of recurrence were concomitant autoimmune disease [hazard ratio (hr), 3.74; 95% confidence interval (ci), 1.05-13.36; p = 0.04], high aspartate aminotransferase (hr, 1.09; 95% ci, 1.03-1.14; p = 0.002), high alanine aminotransferase (hr, 1.09; 95% ci, 1.03-1.20; p = 0.003), and high immunoglobulin g (igg; hr, 1.25; 95% ci, 1.11-1.41; p = 0.0003). 2009-12-17 2023-08-12 Not clear
B J Veldt, J J Poterucha, K D S Watt, R H Wiesner, J E Hay, C B Rosen, J K Heimbach, H L A Janssen, M R Charlto. Insulin resistance, serum adipokines and risk of fibrosis progression in patients transplanted for hepatitis C. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. vol 9. issue 6. 2009-12-02. PMID:19459812. multivariate cox regression analysis showed that insulin resistance (hazard ratio (hr) 2.07; confidence interval (ci) 1.10-3.91, p = 0.024), donor age (hr 1.33;ci 1.08-1.63, p = 0.007) and aspartate aminotransferase (hr 1.03;ci 1.01-1.05, p < 0.001) were significantly associated with a higher probability of developing advanced fibrosis, i.e. 2009-12-02 2023-08-12 Not clear
T V Vygodina, C Pecoraro, D Mitchell, R Gennis, A A Konstantino. Mechanism of inhibition of electron transfer by amino acid replacement K362M in a proton channel of Rhodobacter sphaeroides cytochrome c oxidase. Biochemistry. vol 37. issue 9. 1998-04-03. PMID:9485458. these are denoted as the k-channel (for the highly conserved lysine residue, k362 in rhodobacter sphaeroides cox) and the d-channel (for the highly conserved aspartate gating the channel at the n-side, d132 in r. sphaeroides). 1998-04-03 2023-08-12 Not clear
K Iwata, T Yamasaki, H Saito, S Ito, M Fukahori, T Nakazato, S Naga. [Results of annual health examination for the aged provided by the law that are predictive of increased mortality risk]. [Nihon koshu eisei zasshi] Japanese journal of public health. vol 41. issue 11. 1995-03-31. PMID:7873766. after adjustment for age using cox proportional hazards models, in men liver dysfunction (aspartate aminotransferase > 40 u/l or alanine aminotransferase > 35 u/l), fasting blood glucose > or = 110 mg/dl and glucosuria, and in women serum creatinine > or = 1.2 mg/dl, fasting blood glucose > or = 110 mg/dl and proteinuria were found to be associated with a significantly increased risk of total mortality. 1995-03-31 2023-08-12 Not clear