| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fengjiao Liu, Yaxin Jia, Liwei Zhao, Li-Na Xiao, Xizhen Cheng, Yingying Xiao, Ying Zhang, Yuling Zhang, Huimin Yu, Qiao-En Deng, Yuanyuan Zhang, Yimeng Feng, Junfang Wang, Yonggang Gao, Xuan Zhang, Yunyun Gen. Escin ameliorates CUMS-induced depressive-like behavior via BDNF/TrkB/CREB and TLR4/MyD88/NF-κB signaling pathways in rats. European journal of pharmacology. 2024-10-19. PMID:39426465. |
it also decreased serum adrenal cortical hormone (acth) and corticosterone (cort) levels while increasing 5-ht and brain-derived neurotrophic factor (bdnf) levels in the cums rats, as measured by the enzyme-linked immunosorbent assay (elisa). |
2024-10-19 |
2024-10-22 |
rat |
| María Del Pilar Meza-Rodríguez, Philippe Leff-Gelman, Diana Medina-Bastidas, Miroslava Avila-García, Ricardo Figueroa-Damián, Ignacio Camacho-Arroy. Serotonin, cortisol, and DHEA-S levels in anxious and depressive pregnant women living with HIV. BMC psychology. vol 12. issue 1. 2024-10-18. PMID:39420397. |
imbalances in serotonin (5-ht), dehydroepiandrosterone sulfate (dhea-s), and cortisol (cort) levels can contribute to anx and dep manifestations. |
2024-10-18 |
2024-10-20 |
human |
| María Del Pilar Meza-Rodríguez, Philippe Leff-Gelman, Diana Medina-Bastidas, Miroslava Avila-García, Ricardo Figueroa-Damián, Ignacio Camacho-Arroy. Serotonin, cortisol, and DHEA-S levels in anxious and depressive pregnant women living with HIV. BMC psychology. vol 12. issue 1. 2024-10-18. PMID:39420397. |
this study aimed to characterize 5-ht, dhea-s, and cort plasma levels in mexican pregnant wlwh presenting anx/dep. |
2024-10-18 |
2024-10-20 |
human |
| Wenli Ma, Dayun Sui, Weilun Sun, Ping Yu, Yuangeng Li, Meiqi Guo, Huifeng Wang, Xiaoze Zhang, Xiaofeng Yu, Wenwen Fu, Huali X. 5,7,3',4',5'-Pentamethoxyflavone, a Flavonoid Monomer Extracted From Murraya paniculata (L.) Jack, Alleviates Anxiety Through the A Phytotherapy research : PTR. 2024-09-11. PMID:39261011. |
enzyme-linked immunosorbent assay (elisa) kits were used to analyze the serum levels of corticosterone (cort), 5-hydroxytryptamine (5-ht), gamma-aminobutyric acid (gaba), and cyclic adenosine monophosphate (camp) in the hippocampus. |
2024-09-11 |
2024-09-14 |
mouse |
| Liu Tang, Xiaoqin Cao, Shaoze Chen, Xiao Jiang, Dan Li, Guanghui Che. Dietary Galacto-oligosaccharides Ameliorate Atopic Dermatitis-like Skin Inflammation and Behavioral Deficits by Modulating Gut Microbiota-Brain-Skin Axis. Journal of agricultural and food chemistry. 2024-03-27. PMID:38536703. |
moreover, gos significantly improved the anxiety- and depressive-like symptoms as mirrored by the behavior tests including fst, tst, oft, and ezm through normalizing the neurotransmitter levels of 5-ht, da, ne, and cort in the brain. |
2024-03-27 |
2024-03-30 |
mouse |
| Yi Yang, Yan-E Hu, Yu-Qing Huang, Yi-Fang Jiang, Xi Fu, Feng-Ming Yo. [Tongxie Yaofang regulates tumor-associated macrophage polarization in colorectal cancer under chronic stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 22. 2023-12-19. PMID:38114221. |
enzyme-linked immunosorbent assay was employed to determine the levels of cortisol(cort), 5-hydroxytryptamine(5-ht), norepinephrine(ne), m1-associated inflammatory cytokines [interleukin(il)-1β, il-12, and tumor necrosis factor(tnf)-α], and m2-associated inflammatory cytokines(il-4 and il-10) in the serum. |
2023-12-19 |
2023-12-23 |
mouse |
| Yi Yang, Yan-E Hu, Yu-Qing Huang, Yi-Fang Jiang, Xi Fu, Feng-Ming Yo. [Tongxie Yaofang regulates tumor-associated macrophage polarization in colorectal cancer under chronic stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 22. 2023-12-19. PMID:38114221. |
the results showed that chronic stress increased the immobility time of mice, elevated the serum levels of cort, il-4, and il-10, lowered the levels of 5-ht, ne, il-1β, il-12, and tnf-α, and promoted the growth of subcutaneous tumors. |
2023-12-19 |
2023-12-23 |
mouse |
| Yi Yang, Yan-E Hu, Yu-Qing Huang, Yi-Fang Jiang, Xi Fu, Feng-Ming Yo. [Tongxie Yaofang regulates tumor-associated macrophage polarization in colorectal cancer under chronic stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 22. 2023-12-19. PMID:38114221. |
the treatment with tongxie yaofang shortened the immobility time of mice, lowered the serum levels of cort, il-4, and il-10, elevated the serum levels of 5-ht, ne, il-1β, il-12, and tnf-α, and inhibited the growth of subcutaneous tumors in mice. |
2023-12-19 |
2023-12-23 |
mouse |
| Jiao Ma, Chen-Yang Guo, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Prophylactic Effects of Hemp Seed Oil on Perimenopausal Depression: A Role of HPA Axis. Journal of oleo science. 2023-09-13. PMID:37704445. |
sucrose preference test (spt), forced swimming test (fst), open field test (oft), estrogen receptor α (erα) and estrogen receptor β (erβ) expression, estradiol (e2), follicle stimulating hormone (fsh), luteinizing hormone (lh), cortisol (cort), adrenocorticotropic hormone (acth), corticotropin releasing hormone (crh), norepinephrine (ne), 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5hiaa) levels are measured to evaluate the function of the hypothalamic-pituitary-ovarian (hpo) and hypothalamic-pituitary-adrenal (hpa) axis. |
2023-09-13 |
2023-10-07 |
rat |
| Jiao Ma, Chen-Yang Guo, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Prophylactic Effects of Hemp Seed Oil on Perimenopausal Depression: A Role of HPA Axis. Journal of oleo science. 2023-09-13. PMID:37704445. |
hso treatment significantly improves depression-like behaviors, upregulates the expression of erα and erβ, improves hpo axis function by increasing e2 levels and decreasing fsh and lh levels, reverses hpa axis hyperactivation by decreasing cort, acth, and crh levels, and upregulates ne, 5-ht, and 5hiaa levels in model rats. |
2023-09-13 |
2023-10-07 |
rat |
| Yujuan Zhao, You Kang, Zijian Zhao, Ge Yang, Yansong Gao, Lei Gao, Chao Wang, Shengyu L. Lacticaseibacillus rhamnosus TF318 prevents depressive behavior in rats by inhibiting HPA-axis hyperactivity and upregulating BDNF expression. Neuroscience letters. 2023-08-24. PMID:37619699. |
administration of l. rhamnosus tf318 resulted in lower hippocampal levels of adrenocorticotropic hormone and corticotropin-releasing factor and serum levels of cort and restoration of hippocampal levels of 5-hydroxytryptamine, dopamine, and norepinephrine. |
2023-08-24 |
2023-09-07 |
rat |
| Pei-Pei Li, Shuo Wang, Tao Chen, Ruo-Lan Long, Dan Feng, Yang-Fei Wei, Zhi-Bo Song, Yu-Lin Li, Jing Su. [Comparison of mouse models of depression induced by different modeling methods]. Sheng li xue bao : [Acta physiologica Sinica]. vol 75. issue 3. 2023-06-21. PMID:37340647. |
after modeling, forced swimming test (fst), tail suspension test (tst) and sucrose preference test (spt) were used to detect the behavioral changes of mice, and the serum levels of brain-derived neurotrophic factor (bdnf), 5-hydroxytryptamine (5-ht) and cort were detected with elisa kits. |
2023-06-21 |
2023-08-14 |
mouse |
| Pei-Pei Li, Shuo Wang, Tao Chen, Ruo-Lan Long, Dan Feng, Yang-Fei Wei, Zhi-Bo Song, Yu-Lin Li, Jing Su. [Comparison of mouse models of depression induced by different modeling methods]. Sheng li xue bao : [Acta physiologica Sinica]. vol 75. issue 3. 2023-06-21. PMID:37340647. |
the serum 5-ht levels of model mice from the cort and cc groups were significantly reduced, while the serum bdnf and cort levels of model mice from the cums, cort, and cc groups showed no significant changes. |
2023-06-21 |
2023-08-14 |
mouse |
| M Maetzi Estévez-Cabrera, Fausto Sánchez-Muñoz, Gilberto Pérez-Sánchez, Lenin Pavón, Adrian Hernández-Díazcouder, J Luis Córtes Altamirano, C Soria-Fregoso, Alfonso Alfaro-Rodríguez, Herlinda Bonilla-Jaim. Therapeutic treatment with fluoxetine using the chronic unpredictable stress model induces changes in neurotransmitters and circulating miRNAs in extracellular vesicles. Heliyon. vol 9. issue 2. 2023-02-28. PMID:36852042. |
after cums, the rats performed the fst, and serum levels of cort and six micrornas (mir-16, -21, -144, -155, -146a, -223) were analyzed, as were levels of dopamine, noradrenaline, and serotonin in the prefrontal cortex, hippocampus, and hypothalamus. |
2023-02-28 |
2023-08-14 |
rat |
| Yan Sun, Haiyan Zhu, Rongrong Cheng, Zhengquan Tang, Min Zhan. Outer membrane protein Amuc_1100 of Akkermansia muciniphila alleviates antibiotic-induced anxiety and depression-like behavior in mice. Physiology & behavior. 2022-11-06. PMID:36336146. |
in the present study, a depressed mouse model using a broad-spectrum cocktail mixture resulted in increased anxiety and depression-like behavior, decreased serum and hippocampal levels of 5-hydroxytryptamine (5-ht), and increased serum corticosterone (cort) levels. |
2022-11-06 |
2023-08-14 |
mouse |
| Girdhari Lal Gupta, Lalit Sharma, Manu Sharm. 18β-Glycyrrhetinic Acid Ameliorates Neuroinflammation Linked Depressive Behavior Instigated by Chronic Unpredictable Mild Stress via Triggering BDNF/TrkB Signaling Pathway in Rats. Neurochemical research. 2022-10-28. PMID:36307572. |
the therapy of 18βga dramatically declined cytokines, acth and cort and improved 5ht and norepinephrine in cums rats. |
2022-10-28 |
2023-08-14 |
rat |
| Yajie Hu, Yang Liu, Shize L. Effect of Acute Cold Stress on Neuroethology in Mice and Establishment of Its Model. Animals : an open access journal from MDPI. vol 12. issue 19. 2022-10-14. PMID:36230412. |
subsequently, blood samples were collected and used for the determination of corticosterone (cort), corticotropin-releasing hormone (crh), epinephrine (e), norepinephrine (ne), dopamine (da) and 5-hydroxytryptamine (5-ht) by enzyme-linked immunosorbent assay (elisa). |
2022-10-14 |
2023-08-14 |
mouse |
| Yajie Hu, Yang Liu, Shize L. Effect of Acute Cold Stress on Neuroethology in Mice and Establishment of Its Model. Animals : an open access journal from MDPI. vol 12. issue 19. 2022-10-14. PMID:36230412. |
the physiological basis of these behavioral and emotional changes in mice under different intensity cold stimulation is the fluctuation of cort, crh, e, ne, da and 5-ht. |
2022-10-14 |
2023-08-14 |
mouse |
| Hui Zhao, Meiqiong Jiang, Mingsan Mia. Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model. Journal of healthcare engineering. vol 2022. 2022-04-08. PMID:35392144. |
changes of serotonin (5-ht), dopamine (da), norepinephrine (ne), serum corticosterone (cort), adrenocorticotropic hormone (acth), organ index, and histopathology in brain tissue, to explore the treatment and characteristics of total white glucosides in depression model, were prepared by different stimuli in 21 days. |
2022-04-08 |
2023-08-13 |
rat |
| Jing-Qi Fan, Zi-Qiao Xu, Yuan-Yuan Chen, Wei-Jing Lu, Xiao-Yan Xie, Yu-Ting Wang, Li-Xing Zhuan. Efficacy of Acupuncture for Parkinson's Disease Anxiety: Two-Stage Protocol for a Randomized Controlled Clinical Trial. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-02-21. PMID:35186098. |
the levels of adrenocorticotropic hormone (acth), cortisol (cort), serotonin (5-ht), and corticotropin-releasing factor (crh) in the patients' serum and the scores on the hoehn-yahr rating scale and the unified parkinson's disease rating scale (updrs) will all be considered among the secondary outcomes. |
2022-02-21 |
2023-08-13 |
human |