| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fengjiao Liu, Yaxin Jia, Liwei Zhao, Li-Na Xiao, Xizhen Cheng, Yingying Xiao, Ying Zhang, Yuling Zhang, Huimin Yu, Qiao-En Deng, Yuanyuan Zhang, Yimeng Feng, Junfang Wang, Yonggang Gao, Xuan Zhang, Yunyun Gen. Escin ameliorates CUMS-induced depressive-like behavior via BDNF/TrkB/CREB and TLR4/MyD88/NF-κB signaling pathways in rats. European journal of pharmacology. 2024-10-19. PMID:39426465. |
it also decreased serum adrenal cortical hormone (acth) and corticosterone (cort) levels while increasing 5-ht and brain-derived neurotrophic factor (bdnf) levels in the cums rats, as measured by the enzyme-linked immunosorbent assay (elisa). |
2024-10-19 |
2024-10-22 |
rat |
| Yanlin Tao, Zikang Li, Jinfeng Yuan, Hui Wu, Hailian Shi, Xiaojun Wu, Fei Huan. Dried bear bile exerts its antidepressant effect by modulating adrenal FXR to reduce peripheral glucocorticoid levels. Brain, behavior, & immunity - health. vol 41. 2024-09-18. PMID:39290473. |
we used the chronic unpredictable mild stress (cums) mouse model and fxr agonist gw4064 stimulated mice, as well as h295r human adrenal cortical carcinoma cells, employing behavioral tests, biochemical analysis, and gene expression analysis to assess the effects of dbb treatment on depressive behavior, serum corticosterone (cort) levels, and adrenal fxr and steroid biosynthesis-related gene expression. |
2024-09-18 |
2024-09-20 |
mouse |
| Noriyuki Okudaira, Mi-Ho Akimoto, Takao Susa, Miho Akimoto, Harumi Hisaki, Masayoshi Iizuka, Hiroko Okinaga, Julio A Almunia, Noboru Ogiso, Tomoki Okazaki, Mimi Tamamori-Adach. Accumulation of senescent cells in the adrenal gland induces hypersecretion of corticosterone via IL1β secretion. Aging cell. 2024-05-21. PMID:38769821. |
our findings suggest that the disappearance of cort diurnal oscillation is a characteristic of aging individuals and is caused by the secretion of il1β, one of the sasps, from senescent cells that accumulate in the zf of the adrenal cortex. |
2024-05-21 |
2024-05-27 |
mouse |
| Chuan Jiang, Chaonan Wang, Weizhong Qu, Yuanyuan Wang, Hua Wang, Xin Wei, Mingyan Wang, Qianqian He, Yihan Wang, Lirong Yuan, Yonggang Ga. Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1. Heliyon. vol 9. issue 11. 2023-11-30. PMID:38034773. |
moreover, the levels of crh, adrenal cortical hormone (acth) and corticosterone (cort) in serum also decreased significantly. |
2023-11-30 |
2023-12-10 |
rat |
| Maryam Radahmadi, Kowsar Salehifard, Parham Reis. Invivo synaptic potency, short-term and long-term plasticity at the hippocampal Schaffer Collateral-CA1 Synapses: Role of different light-dark cycles in male rats. Brain research. 2023-07-27. PMID:37499734. |
the present study compared the effects of various l/d cycles on invivo synaptic potency, short-term and long-term plasticity in the hippocampal ca1 area, adrenal glands weight(agws), corticosterone (cort) levels, and body weight differences(bwd) in male rats. |
2023-07-27 |
2023-08-14 |
rat |
| M A Murray, C Soos, K L Machi. The effects of pre-hatch elevated corticosterone and post-hatch restrictive food availability on the HPA axis development of mallard ducks (Anas platyrhynchos). General and comparative endocrinology. 2023-06-27. PMID:37369328. |
stressors trigger the hypothalamic pituitary adrenal (hpa) axis to release corticosterone (cort) which modifies energy homeostasis. |
2023-06-27 |
2023-08-14 |
Not clear |
| M A Murray, C Soos, K L Machi. The effects of pre-hatch elevated corticosterone and post-hatch restrictive food availability on the HPA axis development of mallard ducks (Anas platyrhynchos). General and comparative endocrinology. 2023-06-27. PMID:37369328. |
the hpa axis was assessed at seven weeks by measuring cort at baseline, and following restraint stress, and dexamethasone (negative feedback) and acth (maximal adrenal capacity) challenges. |
2023-06-27 |
2023-08-14 |
Not clear |
| Dominik Langgartner, Mascha Koenen, Sandra Kupfer, Lisa Glogger, Lisa Kurz, Luis Gustavo Perez-Rivas, Marily Theodoropoulou, Michael Noll-Hussong, Sabine Vettorazzi, Jan Tuckermann, Stefan O Rebe. Intact GR dimerization is critical for restraining plasma ACTH levels during chronic psychosocial stress. Neurobiology of stress. vol 24. 2023-05-23. PMID:37215522. |
male c57bl/6n mice exposed to the chronic subordinate colony housing (csc; 19 days) paradigm, a preclinically validated model of chronic psychosocial stress, are characterized by unaffected basal morning plasma corticosterone (cort) concentrations despite adrenal and pituitary hyperplasia and increased adrenocorticotropic hormone (acth) plasma concentrations, compared with single-housed control (shc) mice. |
2023-05-23 |
2023-08-14 |
mouse |
| Jonathan M Branco, Erika Hingst-Zaher, Renee Jordan-Ward, Danielle Dillon, Joe Siegrist, Jason D Fischer, Luis Schiesari, Frank A von Hippel, C Loren Buc. Interrelationships among feather mercury content, body condition and feather corticosterone in a Neotropical migratory bird, the Purple Martin (Progne subis subis). Environmental pollution (Barking, Essex : 1987). 2022-10-07. PMID:36206890. |
because feathers accumulate hg and hormones while growing, quantification of hg and cort in feathers provides an opportunity to retrospectively assess hg exposure and adrenal activity of birds using minimally invasive methods. |
2022-10-07 |
2023-08-14 |
Not clear |
| Alexandria M Szalanczy, Gina Giorgio, Emily Goff, Osborne Seshie, Michael Grzybowski, Jason Klotz, Mackenzie Roberts, Aron M Geurts, Eva E Redei, Leah C Solberg Wood. Keratinocyte-associated Protein 3May Participate in the Stress Response to Impact Adiposity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554436. |
in contrast, krtcap3has low expression in the adrenal glands, with no change after the cort injection. |
2022-05-13 |
2023-08-13 |
rat |
| Brian J Tornabene, Creagh W Breuner, Blake R Hossack, Erica J Cresp. Effects of salinity and a glucocorticoid antagonist, RU486, on waterborne aldosterone and corticosterone of northern leopard frog larvae. General and comparative endocrinology. 2021-12-27. PMID:34958807. |
although sample sizes were limited and further validation and studies are warranted, our findings expand our understanding of the regulation of adrenal steroid responses to salinization in amphibians and proposes new hypotheses regarding the co-regulation of aldo and cort. |
2021-12-27 |
2023-08-13 |
Not clear |
| Mariana Angoa-Pérez, Branislava Zagorac, Dina M Francescutti, Kevin R Theis, Donald M Kuh. Responses to chronic corticosterone on brain glucocorticoid receptors, adrenal gland, and gut microbiota in mice lacking neuronal serotonin. Brain research. vol 1751. 2021-11-30. PMID:33152342. |
neuronal 5ht depletion impaired the feedback regulation of cort levels but had no putative effect on the cort-induced decrease in hippocampal gr expression and the reduction of the adrenal cortex size. |
2021-11-30 |
2023-08-13 |
mouse |
| Suzanne H Austin, Rayna M Harris, April M Booth, Andrew S Lang, Victoria S Farrar, Jesse S Krause, Tyler A Hallman, Matthew MacManes, Rebecca M Calis. Isolating the Role of Corticosterone in the Hypothalamic-Pituitary-Gonadal Transcriptomic Stress Response. Frontiers in endocrinology. vol 12. 2021-08-10. PMID:34149609. |
investigation of the negative impacts of stress on reproduction has largely centered around the effects of the adrenal steroid hormone, corticosterone (cort), and its influence on a system of tissues vital for reproduction-the hypothalamus of the brain, the pituitary gland, and the gonads (the hpg axis). |
2021-08-10 |
2023-08-13 |
Not clear |
| Ashley L Russell, Lauren Miller, Hannah Yi, Rita Keil, Robert J Handa, T John W. Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive-like behaviors and deficits in startle responses. BMC neuroscience. vol 22. issue 1. 2021-06-17. PMID:33509094. |
additionally, cort levels as well as pituitary and adrenal mrna expression were measured following a mild restraint stress. |
2021-06-17 |
2023-08-13 |
mouse |
| Lorna I F Smith, Zidong Zhao, Jamie Walker, Stafford Lightman, Francesca Spig. Activation and expression of endogenous CREB-regulated transcription coactivators (CRTC) 1, 2 and 3 in the rat adrenal gland. Journal of neuroendocrinology. vol 33. issue 1. 2021-06-15. PMID:33314405. |
plasma acth and corticosterone (cort) were measured and the adrenal glands were processed for measurement of protein by western immunoblotting, rna by a quantitative reverse transcriptase-polymerase chain reaction and association of crtc2 and crtc3 with the star promoter by chromatin immunoprecipitation. |
2021-06-15 |
2023-08-13 |
rat |
| Cara M Hueston, Terrence Dea. Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats. Stress (Amsterdam, Netherlands). vol 23. issue 4. 2021-03-24. PMID:31591928. |
while corticosterone (cort) is a primary factor inhibiting il-1 expression, progesterone (prog) is also released by the adrenal glands in male rats in response to stress and also has potent anti-inflammatory properties. |
2021-03-24 |
2023-08-13 |
rat |
| R J Newsom, R J Garcia, J Stafford, C Osterlund, C E O'Neill, H E W Day, S Campea. Remote CB1 receptor antagonist administration reveals multiple sites of tonic and phasic endocannabinoid neuroendocrine regulation. Psychoneuroendocrinology. vol 113. 2021-01-19. PMID:31884322. |
blood, brains, pituitary and adrenal glands were collected immediately after the procedures for analysis of c-fos and cb1r mrnas, corticosterone (cort) and adrenocorticotropin hormone (acth) plasma levels. |
2021-01-19 |
2023-08-13 |
rat |
| Wang Yu-Lu, L U Meng, Wang Yue-Yue, Jia Ru, Chen Yan, Zhang Shu-Ling, Lin Y. [Effect of Puyu Capsules on behavior,HPA axis and CREB-BDNF pathway expression in hippocampus of depressed mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 20. 2020-12-23. PMID:33350271. |
after the behavioral test, the adrenal index was calculated; the levels of serum corticosterone(cort) and adrenocorticotropic hormone(acth) were detected by enzyme-linked immunosorbent assay(elisa); the levels of glucocorticoid receptor(gr), protein expression of brain-derived neurotrophic factor(bdnf), and the ratio of phosphorylated camp response element binding protein(creb) to total creb were detected by western blot to explore the antidepressant function and mechanism of puyu capsules. |
2020-12-23 |
2023-08-13 |
mouse |
| Wang Yu-Lu, L U Meng, Wang Yue-Yue, Jia Ru, Chen Yan, Zhang Shu-Ling, Lin Y. [Effect of Puyu Capsules on behavior,HPA axis and CREB-BDNF pathway expression in hippocampus of depressed mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 20. 2020-12-23. PMID:33350271. |
at the same time, the drug could prevent the change of adrenal index induced by cus and reverse the abnormal activation of cort and acth in the serum of depressed mice. |
2020-12-23 |
2023-08-13 |
mouse |
| Halima Abobaker, Yun Hu, Nagmeldin A Omer, Zhen Hou, Abdulrahman A Idriss, Ruqian Zha. Maternal betaine suppresses adrenal expression of cholesterol trafficking genes and decreases plasma corticosterone concentration in offspring pullets. Journal of animal science and biotechnology. vol 10. 2020-10-01. PMID:31827786. |
laying hens supplemented with betaine demonstrate activated adrenal steroidogenesis and deposit higher corticosterone (cort) in the egg yolk. |
2020-10-01 |
2023-08-13 |
Not clear |