| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer P Jain, Yifei Ma, Carol Dawson-Rose, Glenn-Milo Santos, Alvina Han, Jennifer Price, Judith A Hahn, Phyllis C Tie. The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California. PloS one. vol 19. issue 10. 2024-10-04. PMID:39365789. |
factors independently associated with peth levels ≥50 ng/ml in adjusted models were: identifying as black/african american (adjusted odds ratio [aor] = 8.34, 95% ci = 2.06-33.72), having an alanine transaminase to aspartate aminotransferase ratio > 1 (aor = 3.10, 95% ci = 1.18-8.13), higher high-density lipoprotein levels (aor = 1.31 per 10 mg/dl increase, 95% ci = 1.01-1.70), and consuming a greater number of drinks per week in the past six months (aor = 1.40, 95% ci = 1.10-1.78). |
2024-10-04 |
2024-10-07 |
Not clear |
| Tarique Aziz, Mukesh K Niraj, Shishir Kumar, Rajendra Kumar, Hina Parvee. Effectiveness of Omega-3 Polyunsaturated Fatty Acids in Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Cureus. vol 16. issue 8. 2024-09-30. PMID:39347373. |
omega-3 supplementation significantly decreased alanine aminotransferase (alt) (mean difference = -2.12, 95% confidence interval (ci) = -3.36, -0.87) and aspartate aminotransferase (ast) (mean difference = -1.50, 95% ci = -2.59, -0.42). |
2024-09-30 |
2024-10-02 |
human |
| Peng Li, Man Zhu, Ao Gao, Haili Guo, An Fu, Anqi Zhao, Daihong Gu. Clinical Characteristics of Moxifloxacin-Related Arrhythmias and Development of a Predictive Nomogram: A Case Control Study. Journal of clinical pharmacology. 2024-08-02. PMID:39092985. |
independent risk factors included medication duration (odds ratio [or] 1.211, 95% confidence interval [ci] 1.156-1.270), concomitant use of meropenem (or 4.977, 95% ci 2.568-9.644), aspartate aminotransferase >40 u/l (or 3.728, 95% ci 1.800-7.721), glucose >6.1 mmol/l (or 2.377, 95% ci 1.531-3.690), and abnormally elevated level of amino-terminal brain natriuretic peptide precursor (or 2.908, 95% ci 1.640-5.156). |
2024-08-02 |
2024-08-05 |
Not clear |
| Ilaria Giangrandi, Monica Dinu, Antonia Napoletano, Valentina Maggini, Niccolò Lombardi, Giada Crescioli, Eugenia Gallo, Vittorio Mascherini, Michele Antonelli, Davide Donelli, Alfredo Vannacci, Fabio Firenzuoli, Francesco Sof. Licorice and liver function in patients with primary liver disease: A systematic review and meta-analysis of RCTs. Phytotherapy research : PTR. 2024-07-30. PMID:39079711. |
licorice significantly reduced alanine aminotransferase (alt) by 15.63 u/l (95% ci: -25.08, -6.18; p = 0.001) and aspartate aminotransferase (ast) by 7.37 u/l (95% ci: -13.13, -1.61; p = 0.01) compared to control groups. |
2024-07-30 |
2024-08-02 |
human |
| Jue Zhang, Chao Chen, Zhaojun Xia, Xi Xiong, Ping Liu, Yanping Xu, Xiufeng Liu, Zixiong L. Prognostic analysis of systemic antitumor therapy in young patients with advanced liver cancer: A cohort study. Oncology letters. vol 28. issue 3. 2024-07-11. PMID:38988447. |
in the subgroup analysis, male sex [hr, 1.73; 95% confidence interval (ci), 1.07-2.79], pathological diagnosis (hr, 1.79; 95% ci, 1.10-2.91), previous surgical treatment (hr, 2.16; 95% ci, 1.18-3.95), no tumor thrombus (hr, 2.45; 95% ci, 1.22-4.93), increased alanine aminotransferase (hr, 2.23; 95% ci, 1.07-4.65), increased aspartate aminotransferase (hr, 3.22; 95% ci, 1.62-6.39), normal total bilirubin (hr, 1.77; 95% ci, 1.09-2.87) and increased afp (hr, 2.02; 95% ci, 1.19-3.41) were associated with shorter survival time in group a compared with those in group b (p<0.05). |
2024-07-11 |
2024-07-13 |
Not clear |
| Claudius Mayer, Till Ittermann, Sabine Schipf, Stefan Gross, Simon Kim, Jan Schielke, Robin Bülow, Jens-Peter Kühn, Markus M Lerch, Henry Völzke, Stephan Burkhard Felix, Martin Bahls, Giovanni Targher, Marcus Dörr, Marcello Ricardo Paulista Marku. Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania. European journal of sport science. vol 24. issue 6. 2024-06-14. PMID:38874978. |
specifically, a 10-kg lower hgs was associated with a 0.59% (95% confidence interval [ci]: 0.24-0.94; p = 0.001) higher lfc, a 0.051 µkatal/l (95% ci: 0.005-0.097; p = 0.031) higher gamma-glutamyltransferase (ggt) concentration and a 0.010 µkatal/l (95% ci: 0.001-0.020; p = 0.023) higher aspartate aminotransferase (ast) concentration. |
2024-06-14 |
2024-06-16 |
human |
| Adèle Léger, Simon B Cormier, Arianne Blanchard, Hichem A Menail, Nicolas Pichau. Investigating the thermal sensitivity of key enzymes involved in the energetic metabolism of three insect species. The Journal of experimental biology. 2024-04-29. PMID:38680096. |
specifically, we measured activities of enzymes involved in glycolysis (hexokinase, hk; pyruvate kinase, pk; and lactate dehydrogenase, ldh), pyruvate oxidation and the tricarboxylic acid cycle (pyruvate dehydrogenase, pdh; citrate synthase, cs; malate dehydrogenase, mdh; and aspartate aminotransferase, aat), the electron transport system (complex i, ci; complex ii, cii; mitochondrial glycerol-3-phosphate dehydrogenase, mg3pdh; proline dehydrogenase, prodh; and complex iv, civ) as well as atp synthase (cv) at 18, 24, 30, 36, 42 and 45˚c. |
2024-04-29 |
2024-05-01 |
drosophila_melanogaster |
| Mengyang Yu, Chengying Zhang, Sitong Wan, Yang Lu, Yufei Wang, Ting Liu, Huimin Wang, Wei Chen, Yahua Li. NEW PREDICTIVE BIOMARKERS FOR SCREENING COVID-19 PATIENTS WITH RHABDOMYOLYSIS IN COMBINATION WITH CYSTATIN C. Shock (Augusta, Ga.). vol 61. issue 4. 2024-04-11. PMID:38010067. |
multivariate analysis revealed that sao 2 (hazard ratio [hr], 0.946; 95% confidence interval [ci], 0.906-0.987; p = 0.011), cysc (hr, 2.124; 95% ci, 1.223-3.689; p = 0.008), aspartate aminotransferase (ast) (hr, 1.009; 95% ci, 1.000-1.018; p = 0.041), and hypersensitive c-reactive protein (hr, 1.005; 95% ci, 1.000-1.010; p = 0.045) were significantly associated with survivals. |
2024-04-11 |
2024-04-14 |
human |
| Chun Zhang, Feng Lin, Deng-Fang Guo, Qing-Lin Wang, De-Xian Xiao, Jian-Yuan Lin, Shi Che. Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study. PloS one. vol 19. issue 4. 2024-04-08. PMID:38578756. |
conversely, the results for alkaline phosphatase (alp) (or = 0.997, 95%ci: 0.992-1.002, p = 0.197) and aspartate aminotransferase (ast) (or = 0.939, 95%ci: 0.794-1.111, p = 0.464) did not show a causal effect on acute pancreatitis. |
2024-04-08 |
2024-04-10 |
Not clear |
| Yuuto Tonouchi, Yuki Kataok. Predictive Factors for 30-Day Readmissions in Elderly Patients With Pneumonia: A Single-Center Retrospective Cohort Study. Cureus. vol 15. issue 12. 2024-01-31. PMID:38292965. |
in patients with aspartate transaminase of 38 u/l or more, the or for readmission was 2.99 (95% ci = 1.07-7.68). |
2024-01-31 |
2024-02-02 |
Not clear |
| Christoph Meyer, Damian Hertig, Janine Arnold, Christian Urzi, Sandra Kurth, Johannes A Mayr, André Schaller, Peter Vermathen, Jean-Marc Nuoffe. Complex I, V, and MDH2 deficient human skin fibroblasts reveal distinct metabolic signatures by Journal of inherited metabolic disease. 2023-12-12. PMID:38084664. |
the extracellular metabolome was discriminative for separating controls from defects but not the specific defects, whereas the intracellular metabolome suggests ci and cv changes and revealed clear mdh2 defect-specific changes in metabolites associated with the tca cycle, malate aspartate shuttle, and the choline metabolism, which are pronounced under galactose condition. |
2023-12-12 |
2023-12-17 |
human |
| Yuansong Zhuang, Quanxu An, Fuhang Wang, Dongjian Han, Zhentao Qiao, Qingjiao Jiang, Miaomiao Liu, Yuhang Li, Jiahong Shangguan, Xuanye Bi, Deliang She. The role of circulating biomarkers in predicting the 30-day mortality of immune checkpoint inhibitors-related myocarditis: a retrospective cohort study. Internal and emergency medicine. 2023-12-12. PMID:38085435. |
after adjusting for potential confounding factors using multivariate analysis tools, we demonstrated the excellent performance of biomarkers in predicting 30-day mortality in patients with icis-m, including plt (hazard ratio (hr), 1.07; 95% confidence interval (95%ci), 1.01-1.14; p = 0.028), alt (hr, 1.23; 95%ci, 1.06-1.41; p = 0.005), ast(hr, 1.06; 95%ci, 1.01-1.10; p = 0.015), ldh (hr, 1.15; 95%ci, 1.04-1.26; p = 0.004), troponin i(hr, 1.44; 95%ci, 1.09-1.89; p = 0.009), plr (blood plate/lymphocyte) (hr, 1.04; 95% ci, 1.01-1.07; p = 0.024), lar (lactate dehydrogenase/albumin) (hr, 1.05; 95%ci, 1.01-1.09; p = 0.012), and aar (aspartate transaminase/albumin) (hr, 1.18; 95%ci, 1.00-1.39; p = 0.048). |
2023-12-12 |
2023-12-17 |
Not clear |
| Rongna Lian, Qianqian Liu, Gengchen Jiang, Xiangyu Zhang, Huiyu Tang, Jing Lu, Ming Yan. Blood biomarkers for sarcopenia: A systematic review and meta-analysis of diagnostic test accuracy studies. Ageing research reviews. 2023-11-30. PMID:38036104. |
the aspartate aminotransferase to alanine aminotransferase ratio demonstrated a pooled sensitivity of 62% (95% ci 56% - 67%) and a pooled specificity of 66% (95% ci 60% - 72%) (3 studies, 11,146 participants). |
2023-11-30 |
2023-12-10 |
human |
| Mi Dai, Lei Luo, Caiyan Xie, Zhongbao Chen, Mingzhe Zhang, Yan Xie, Xuejun Shang, Xubo Shen, Kunming Tian, Yuanzhong Zho. Single and Joint Associations of Polycyclic Aromatic Hydrocarbon Exposure with Liver Function during Early Pregnancy. Toxics. vol 11. issue 10. 2023-10-27. PMID:37888713. |
we found that each 1% increment of urinary 2-hydroxyphenanthrene (2-oh-phe) was associated with 3.36% (95% ci: 0.40%, 6.40%) higher alanine aminotransferase (alt) and 2.22% (95% ci: 0.80%, 3.67%) higher aspartate aminotransferase (ast). |
2023-10-27 |
2023-11-08 |
Not clear |
| Stamatina Vogli, Androniki Naska, Georgios Marinos, Maria-Iosifina Kasdagli, Philippos Orfano. The Effect of Vitamin E Supplementation on Serum Aminotransferases in Non-Alcoholic Fatty Liver Disease (NAFLD): A Systematic Review and Meta-Analysis. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686767. |
regarding aspartate aminotransferase (ast), patients in the experimental group experienced a reduction in serum levels, though smaller in absolute values [ast md = -4.65 iu/l, 95% ci (-7.44, -1.86) in studies conducted in asian populations] and of lower precision in non-asian studies [md = -5.60 iu/l, 95% ci (-11.48, 0.28)]. |
2023-09-09 |
2023-10-07 |
Not clear |
| Boya Zhang, Ying Zhou, Junyu Gu. Association of volatile methylsiloxanes exposure with non-alcoholic fatty liver disease among Chinese adults. Environmental pollution (Barking, Essex : 1987). 2023-07-03. PMID:37399934. |
with per doubling increase in the total cvmss, we observed a 1.40 (95%ci: 0.31, 2.48) increase in alanine aminotransferase (alt), a 1.56 (95%ci: 0.52, 2.61) increase in aspartate aminotransferase (ast) and a 0.04 (0.00, 0.09) increase in nafld index. |
2023-07-03 |
2023-08-14 |
human |
| Laurence J Dobbie, Daniel J Cuthbertson, Theresa J Hydes, Uazman Alam, Sizheng Steven Zha. Mendelian randomisation reveals Sodium-glucose Cotransporter-1 inhibition's potential in reducing Non-Alcoholic Fatty Liver Disease risk. European journal of endocrinology. vol 188. issue 6. 2023-06-29. PMID:37343141. |
genetically proxied sglt-1i was associated with reduced nafld risk (or 0.36; 95%ci 0.15, 0.87; p = .023) per 1 mmol/mol hba1c reduction, and with reductions in liver enzymes (alanine transaminase, aspartate transaminase, gamma-glutamyl transferase). |
2023-06-29 |
2024-06-23 |
Not clear |
| Chih-Wen Wang, Szu-Chia Chen, Da-Wei Wu, Hung-Hsun Lin, Huang-Chi Chen, Chih-Hsing Hung, Chao-Hung Ku. Arsenic exposure associated with lung interstitial changes in non-smoking individuals living near a petrochemical complex: A repeated cross-sectional study. Environmental pollution (Barking, Essex : 1987). 2023-05-25. PMID:37230174. |
after controlling for age, gender, body mass index, platelet counts, hypertension, aspartate aminotransferase, cholesterol, hba1c, and educational levels, we observed a significant positive association between a unit increase in log urinary arsenic concentrations and the risk of lung fibrotic changes in both cross-sectional study 2016 (odds ratio [or] = 1.40, 95% confidence interval [ci] = 1.04-1.90, p = 0.028) and cross-sectional study 2018 (or = 3.03, 95% ci = 1.38-6.63, p = 0.006). |
2023-05-25 |
2023-08-14 |
human |
| Thitiya Lukkunaprasit, Amarit Tansawet, Suparee Boonmanunt, Abhasnee Sobhonslidsuk, Gareth J McKay, John Attia, Ammarin Thakkinstia. An updated meta-analysis of effects of curcumin on metabolic dysfunction-associated fatty liver disease based on available evidence from Iran and Thailand. Scientific reports. vol 13. issue 1. 2023-04-10. PMID:37037891. |
from an updated meta-analysis, curcumin demonstrated significant improvement in aspartate and alanine aminotransferase with pooled mean difference [95% confidence interval (ci)] of -3.90 (-5.97, -1.82) and -5.61 (-9.37, -1.85) units/l, respectively. |
2023-04-10 |
2023-08-14 |
Not clear |
| Chang Meng, Zejun Song, Lingnan Zhang, Yu Geng, Jing Sun, Guobin Miao, Peng Li. Effects of losartan in patients with NAFLD: A meta-analysis of randomized controlled trial. Open life sciences. vol 18. issue 1. 2023-03-27. PMID:36970603. |
the meta-analysis demonstrated that aspartate transaminase was significantly affected by losartan therapy (mean difference [md] = -5.34, 95% confidence interval [ci] [-6.54, -4.13], |
2023-03-27 |
2023-08-14 |
Not clear |