| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ya'el Courtney, Alexandra Hochstetler, Maria K Lehtine. Choroid Plexus Pathophysiology. Annual review of pathology. 2024-10-09. PMID:39383438. |
this review examines the crucial roles of the choroid plexus (chp) in central nervous system (cns) pathology, emphasizing its involvement in disease mechanisms and therapeutic potential. |
2024-10-09 |
2024-10-12 |
human |
| Valentina Visani, Mattia Veronese, Francesca B Pizzini, Annalisa Colombi, Valerio Natale, Corina Marjin, Agnese Tamanti, Julia J Schubert, Noha Althubaity, Inés Bedmar-Gómez, Neil A Harrison, Edward T Bullmore, Federico E Turkheimer, Massimiliano Calabrese, Marco Castellar. ASCHOPLEX: A generalizable approach for the automatic segmentation of choroid plexus. Computers in biology and medicine. vol 182. 2024-09-26. PMID:39326265. |
the choroid plexus (chp) plays a vital role in brain homeostasis, serving as part of the blood-cerebrospinal fluid barrier, contributing to brain clearance pathways and being the main source of cerebrospinal fluid. |
2024-09-26 |
2024-09-29 |
human |
| Lin Lin, Yang Chen, Kai He, Shamseldin Metwally, Roshani Jha, Okan Capuk, Mohammad Iqbal H Bhuiyan, Gazal Singh, Guodong Cao, Yan Yin, Dandan Su. Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation. Journal of neuroinflammation. vol 21. issue 1. 2024-09-11. PMID:39256783. |
the choroid plexus (chp) helps maintain the homeostasis of the brain by forming the blood-csf barrier via tight junctions (tj) at the choroid plexus epithelial cells, and subsequently preventing neuroinflammation by restricting immune cells infiltration into the central nervous system. |
2024-09-11 |
2024-09-13 |
Not clear |
| Cassandre Landes-Château, Vito Ag Ricigliano, Lydiane Mondot, Eric Thouvenot, Pierre Labauge, Céline Louapre, Hélène Zéphir, Françoise Durand-Dubief, Emmanuelle Le Page, Aksel Siva, Mikael Cohen, Arya Yazdan Panah, Christina J Azevedo, Darin T Okuda, Bruno Stankoff, Christine Lebrun-Fréna. Choroid plexus enlargement correlates with periventricular pathology but not with disease activity in radiologically isolated syndrome. Multiple sclerosis (Houndmills, Basingstoke, England). 2024-09-09. PMID:39246289. |
choroid plexus (chp) enlargement is an emerging radiological biomarker in multiple sclerosis (ms). |
2024-09-09 |
2024-09-11 |
Not clear |
| Kim Hoa Ho, Marleen Trapp, Catello Guida, Ekaterina L Ivanova, Anchel De Jaime-Soguero, Ammar Jabali, Christian Thomas, Alena Salasova, Ondřej Bernatík, Chiara Salio, Sandra Horschitz, Martin Hasselblatt, Marco Sassoe-Pognetto, Lukáš Čajánek, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Sergio P Acebrón, Peter Angel, Philipp Koch, Annarita Patriz. Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus. Neuro-oncology. 2024-08-31. PMID:39215664. |
choroid plexus (chp) is the secretory epithelial structure located in brain ventricles. |
2024-08-31 |
2024-09-04 |
Not clear |
| Zhuangzhuang Geng, Yen Teng Tai, Qiang Wang, Zhonghua Ga. AUTS2 disruption causes neuronal differentiation defects in human cerebral organoids through hyperactivation of the WNT/β-catenin pathway. Scientific reports. vol 14. issue 1. 2024-08-22. PMID:39174599. |
our transcriptomic analyses revealed that the absence of auts2 in cerebral organoids reduces the populations of cells committed to the neuronal lineage, resulting in an overabundance of cells with a transcription profile resembling that of choroid plexus (chp) cells. |
2024-08-22 |
2024-08-25 |
human |
| Huixin Xu, Peter Lotfy, Sivan Gelb, Aja Pragana, Christine Hehnly, Lillian I J Byer, Frederick B Shipley, Miriam E Zawadzki, Jin Cui, Liwen Deng, Milo Taylor, Mya Webb, Hart G W Lidov, Mark L Andermann, Isaac M Chiu, Jose Ordovas-Montanes, Maria K Lehtine. The choroid plexus synergizes with immune cells during neuroinflammation. Cell. 2024-08-01. PMID:39089253. |
the choroid plexus (chp) is a vital brain barrier and source of cerebrospinal fluid (csf). |
2024-08-01 |
2024-08-05 |
mouse |
| Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M Tijms, Charlotte E Teunissen, Suzanne E Schindler, Frans Verhey, Inez Ramakers, Pablo Martinez-Lage, Mikel Tainta, Rik Vandenberghe, Jolien Schaeverbeke, Sebastiaan Engelborghs, Ellen De Roeck, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Yvonne Freund-Levi, Simon Lovestone, Johannes Streffer, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E Vandenbroucke, Stephanie J B Vo. Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies. Fluids and barriers of the CNS. vol 21. issue 1. 2024-07-17. PMID:39020361. |
structural and functional changes of the choroid plexus (chp) have been reported in alzheimer's disease (ad). |
2024-07-17 |
2024-07-20 |
mouse |
| Jiaxin Li, Yueqin Hu, Yunzhi Xu, Xue Feng, Craig H Meyer, Weiying Dai, Li Zha. Associations between the choroid plexus and tau in Alzheimer's disease using an active learning segmentation pipeline. Fluids and barriers of the CNS. vol 21. issue 1. 2024-07-12. PMID:38997764. |
the cerebrospinal fluid (csf), primarily generated by the choroid plexus (chp), is the major carrier of the glymphatic system. |
2024-07-12 |
2024-07-15 |
Not clear |
| Jiwei Jiang, Zhizheng Zhuo, Anxin Wang, Wenyi Li, Shirui Jiang, Yunyun Duan, Qiwei Ren, Min Zhao, Linlin Wang, Shiyi Yang, Maher Un Nisa Awan, Yaou Liu, Jun X. Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer's continuum. Alzheimer's research & therapy. vol 16. issue 1. 2024-07-04. PMID:38961406. |
enlarged choroid plexus (chp) volume has been reported in patients with alzheimer's disease (ad) and inversely correlated with cognitive performance. |
2024-07-04 |
2024-07-10 |
Not clear |
| Michael J Pearson, Ruth Wagstaff, Rebecca J William. Choroid plexus volumes and auditory verbal learning scores are associated with conversion from mild cognitive impairment to Alzheimer's disease. Brain and behavior. vol 14. issue 7. 2024-07-03. PMID:38956818. |
recent evidence suggests that the choroid plexus (chp), neural substrates implicated in brain clearance, undergo volumetric changes in mci and ad. |
2024-07-03 |
2024-07-06 |
Not clear |
| Aleksandr Taranov, Alicia Bedolla, Eri Iwasawa, Farrah N Brown, Sarah Baumgartner, Elizabeth M Fugate, Joel Levoy, Steven A Crone, June Goto, Yu Lu. The choroid plexus maintains adult brain ventricles and subventricular zone neuroblast pool, which facilitates poststroke neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 28. 2024-07-02. PMID:38954546. |
the brain's neuroreparative capacity after injuries such as ischemic stroke is partly contained in the brain's neurogenic niches, primarily the subventricular zone (svz), which lies in close contact with the cerebrospinal fluid (csf) produced by the choroid plexus (chp). |
2024-07-02 |
2024-07-06 |
mouse |
| Eric Klein, Sophie Marsh, Jordan Becker, Mark Andermann, Maria Lehtinen, Christopher I Moor. BioLuminescent OptoGenetics in the choroid plexus: integrated opto- and chemogenetic control Neurophotonics. vol 11. issue 2. 2024-07-01. PMID:38948888. |
bioluminescent optogenetics in the choroid plexus: integrated opto- and chemogenetic control the choroid plexus (chp) epithelial network displays diverse dynamics, including propagating calcium waves and individuated fluctuations in single cells. |
2024-07-01 |
2024-07-03 |
Not clear |
| Inyoung Jeong, Søren N Andreassen, Linh Hoang, Morgane Poulain, Yongbo Seo, Hae-Chul Park, Maximilian Fürthauer, Nanna MacAulay, Nathalie Jurisch-Yaks. The evolutionarily conserved choroid plexus contributes to the homeostasis of brain ventricles in zebrafish. Cell reports. vol 43. issue 6. 2024-06-06. PMID:38843394. |
the choroid plexus (chp) produces cerebrospinal fluid (csf). |
2024-06-06 |
2024-06-10 |
zebrafish |
| Mohammed R Shaker, Andrii Slonchak, Bahaa Al-Mhanawi, Sean D Morrison, Julian D J Sng, Justin Cooper-White, Alexander A Khromykh, Ernst J Wolvetan. Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2. Science advances. vol 10. issue 23. 2024-06-05. PMID:38838150. |
choroid plexus (chp) plays critical roles in barrier function and immune response modulation and expresses the ace2 receptor and the chromosome 21-encoded tmprss2 protease, suggesting its substantial role in establishing sars-cov-2 infection in the brain. |
2024-06-05 |
2024-06-08 |
Not clear |
| b' Martin Sl\\xc3\\xa1dek, Pavel Houdek, Jihwan Myung, Kateryna Semenovykh, Tereza Do\\xc4\\x8dkal, Alena Sumov\\xc3\\xa. The circadian clock in the choroid plexus drives rhythms in multiple cellular processes under the control of the suprachiasmatic nucleus. Fluids and barriers of the CNS. vol 21. issue 1. 2024-05-28. PMID:38802875.' |
choroid plexus (chp), the brain structure primarily responsible for cerebrospinal fluid production, contains a robust circadian clock, whose role remains to be elucidated. |
2024-05-28 |
2024-06-03 |
mouse |
| Weili Kong, Julie Frouard, Guorui Xie, Michael J Corley, Ekram Helmy, Gang Zhang, Roland Schwarzer, Mauricio Montano, Peter Sohn, Nadia R Roan, Lishomwa C Ndhlovu, Li Gan, Warner C Green. Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids. PNAS nexus. vol 3. issue 5. 2024-05-13. PMID:38737767. |
utilizing two different inducible pluripotent stem cell-derived brain organoid models (cerebral and choroid plexus [chp] organoids) containing microglia, we investigated the pathogenic changes associated with hiv infection. |
2024-05-13 |
2024-05-27 |
human |
| Yingfeng Wan, Xiongjie Fu, Tianjie Zhang, Ya Hua, Richard F Keep, Guohua X. Choroid plexus immune cell response in murine hydrocephalus induced by intraventricular hemorrhage. Fluids and barriers of the CNS. vol 21. issue 1. 2024-04-23. PMID:38654318. |
despite proximity to ivh, the immune cell response at the choroid plexus (chp) has been relatively understudied. |
2024-04-23 |
2024-04-26 |
Not clear |
| Zhe Sun, Chenyang Li, Marco Muccio, Li Jiang, Arjun Masurkar, Sagar Buch, Yongsheng Chen, Jiangyang Zhang, E Mark Haacke, Thomas Wisniewski, Yulin G. Vascular Aging in the Choroid Plexus: A 7T Ultrasmall Superparamagnetic Iron Oxide (USPIO)-MRI Study. Journal of magnetic resonance imaging : JMRI. 2024-04-08. PMID:38587279. |
the choroid plexus (chp), a densely vascularized structure, has drawn increasing attention for its involvement in brain homeostasis and waste clearance. |
2024-04-08 |
2024-04-10 |
Not clear |
| Erica Moore, Sushma Bharrhan, Deepak A Rao, Fernando Macian, Chaim Putterma. Characterisation of choroid plexus-infiltrating T cells reveals novel therapeutic targets in murine neuropsychiatric lupus. Annals of the rheumatic diseases. 2024-03-26. PMID:38531610. |
in murine npsle models, choroid plexus (chp)-infiltrating t cells have not been fully evaluated as drivers of neuropsychiatric disease. |
2024-03-26 |
2024-03-29 |
Not clear |