Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Walaa Bayoumie El Gazzar, Amina A Farag, Mohamed Samir, Heba Bayoumi, Heba S Youssef, Yasmin Mohammed Marei, Shimaa K Mohamed, Azza M Marei, Reham M Abdelfatah, Manal Moustafa Mahmoud, Elshaimaa Ahmed Fahmy Aboelkomsan, Eman Kamel M Khalfallah, Hala Magdy Anwe. Berberine chloride loaded nano-PEGylated liposomes attenuates imidacloprid-induced neurotoxicity by inhibiting NLRP3/Caspase-1/GSDMD-mediated pyroptosis. BioFactors (Oxford, England). 2024-07-29. PMID:39074847. |
the histopathological changes, anti-oxidant and oxidative stress markers (gsh, sod, and mda), proinflammatory cytokines (il1β and tnf-α), microglia phenotype markers (cd86 and inos for m1; cd163 for m2), the canonical pyroptotic pathway markers (nlrp3, caspase-1, gsdmd, and il-18) and alzheimer's disease markers (neprilysin and beta amyloid [aβ] deposits) were assessed. |
2024-07-29 |
2024-08-02 |
rat |
Keke Zhang, Zhen Qin, Jinyan Chen, Gengyin Guo, Xiaokun Jiang, Feng Wang, Jianfeng Zhuang, Zhen Zhan. TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage. Aging. vol 15. 2024-01-05. PMID:38180747. |
antagonism of trpv1 was effective in ameliorating neurological impairment, brain edema, neuronal damage, and reducing the inflammatory response (evidenced by reducing the number of cd16/32 positive microglia/macrophages, inhibiting the expression of cd16, cd32, cd86, il-1b, tnf-a and blocking nlrp3 inflammasome activation). |
2024-01-05 |
2024-01-07 |
Not clear |
Michael J Butler, Nicholas P Deems, Stephanie Muscat, Christopher M Butt, Martha A Belury, Ruth M Barriento. Dietary DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined carbohydrates. Brain, behavior, and immunity. vol 98. 2021-12-09. PMID:34425209. |
these memory deficits were accompanied by increased expression of inflammatory genes, such as il-1β, cd11b, mhc class ii, cd86, nlrp3, and complement component 3, in the hippocampus and amygdala of aged rats. |
2021-12-09 |
2023-08-13 |
rat |