| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Faryal Altaf, Nismat Javed, Haider Ghazanfar, Anil De. Schwann Cell Hamartoma Presenting as a Colonic Polyp: A Rare Case Report With a Literature Review. Cureus. vol 16. issue 4. 2024-05-06. PMID:38707060. |
characteristically, these hamartomas test positive for s-100 protein but do not exhibit markers typical of other gastrointestinal growths, such as gastrointestinal stromal tumors (negative for kit), leiomyomas (negative for smooth muscle actin), neurofibromas (negative for cd34), and perineuromas (negative for epithelial membrane antigen or claudin-1). |
2024-05-06 |
2024-05-08 |
Not clear |
| Daisuke Sano, Takako Kihara, Jiayin Yuan, Neinei Kimura, Mizuka Ohkouchi, Yuka Hashikura, Shuichi Ohkubo, Seiichi Hirot. Characterization of cell line with dedifferentiated GIST-like features established from cecal GIST of familial GIST model mice. Pathology international. 2023-02-24. PMID:36825754. |
since the established cells showed spindle-shaped morphology with atypical nuclei, and since immunohistochemistry revealed that they were positive for α-sma but negative for kit, cd34 and desmin, the phenotypes of the cells were reminiscent of dedifferentiated gist-like ones but not the usual gist-like ones. |
2023-02-24 |
2023-08-14 |
mouse |
| Mizuki Tamai, Atsushi Shiozaki, Hitoshi Fujiwara, Hirotaka Konishi, Jun Kiuchi, Takuma Ohashi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Ryo Morimura, Yoshiaki Kuriu, Hisashi Ikoma, Takeshi Kubota, Kazuma Okamoto, Eigo Otsuj. [Mediastinoscope-Assisted Transhiatal Esophagectomy for Esophageal Gastrointestinal Stromal Tumor(GIST)-A Case Report]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 48. issue 13. 2022-01-19. PMID:35045486. |
esophagogastroduodenoscopy revealed a submucosal tumor of 40×25 mm with ulceration in the lower thoracic esophagus and endoscopic ultrasonographic fine needle aspiration histology showed kit(+), cd34(+), dog-1(+), desmin(-), s-100 protein(-). |
2022-01-19 |
2023-08-13 |
Not clear |
| Hitoshi Kameyama, Tatsuo Kanda, Yosuke Tajima, Yoshifumi Shimada, Hiroshi Ichikawa, Takaaki Hanyu, Takashi Ishikawa, Toshifumi Waka. Management of rectal gastrointestinal stromal tumor. Translational gastroenterology and hepatology. vol 3. 2020-10-01. PMID:29552659. |
immunohistochemical evaluation finds that most rectal gist tumors are cd117 (kit) positive, and are sometimes cd34, platelet-derived growth factor receptor alpha (pdgfra), smooth muscle actin, s-100, or vimentin positive. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jiro Shimazaki, Takanobu Tabuchi, Kiyotaka Nishida, Akira Takemura, Hideki Kajiyama, Gyo Motohashi, Shuji Suzuk. Emergency surgery for hemorrhagic shock caused by a gastrointestinal stromal tumor of the ileum: A case report. Molecular and clinical oncology. vol 5. issue 1. 2020-09-30. PMID:27330776. |
histological examination of the excised tumor revealed proliferation of spindle-shaped cells, and immunohistochemical staining of the tumor was positive for cd34, kit and α-smooth muscle actin, but negative for s-100 protein. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hidehiko Uno, Yoshihiro Takahara, Takahiro Nishida, Tatsuya Ohno, Teisuke Komats. [A Case of Laparoscopic Local Resection of the Stomach for an Inflammatory Myofibroblastic Tumor]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 46. issue 13. 2020-04-21. PMID:32157057. |
an endoscopic ultrasound-guided fine needle aspiration biopsy showed spindle-shaped cells with kit, cd34, desmin, and s-100 all testing negative. |
2020-04-21 |
2023-08-13 |
Not clear |
| Tadashi Terad. Smooth muscles and stem cells of embryonic guts express KIT, PDGFRRA, CD34 and many other stem cell antigens: suggestion that GIST arise from smooth muscles and gut stem cells. International journal of clinical and experimental pathology. vol 6. issue 6. 2013-12-23. PMID:23696920. |
in adult gastrointestinal walls (n=30), kit, cd34, pdgfra, and s100 proteins were expressed in auerbach's nerve plexus and icc. |
2013-12-23 |
2023-08-12 |
human |
| Tadashi Terad. TDT (-), KIT (+), CD34 (+), CD99 (+) precursor T lymphoblastic leukemia/lymphoma. International journal of clinical and experimental pathology. vol 5. issue 2. 2012-06-21. PMID:22400079. |
although tdt was negative, other precursor cell markers (kit, cd34, and cd99) were positive and the lymphoid cells showed t-cell lineage, the diagnosis was t-lbl. |
2012-06-21 |
2023-08-12 |
Not clear |
| Jiro Ogino, Hiroko Asanuma, Shinji Sakurai, Yoshihiro Matsuno, Naoyuki Miyokawa, Katsushige Yamashiro, Yuichiro Fukazawa, Shunji Muraoka, Yasuyuki Iwaki, Nobuo Kondo, Tadashi Hasegaw. Use of tissue microarrays and immunohistochemistry to standardize the diagnosis of gastrointestinal stromal tumors. Pathology international. vol 60. issue 11. 2011-01-28. PMID:20946519. |
we assessed the concordance among seven general pathologists with respect to histologic diagnosis and interpretation of c-kit proto-oncogene (kit) and platelet-derived growth factor receptor alpha (pdgfra) immunostaining of 36 cases of primary spindle-cell tumor, predominantly of the gastrointestinal tract, mesentery, and retroperitoneum, based on review of a tissue microarray (tma) subjected to immunohistochemistry with antibodies to kit/cd117, pdgfra, vimentin, desmin, smooth muscle action, cd34, and s-100 protein. |
2011-01-28 |
2023-08-12 |
Not clear |
| Markku Miettinen, Hala R Makhlouf, Leslie H Sobin, Jerzy Lasot. Plexiform fibromyxoma: a distinctive benign gastric antral neoplasm not to be confused with a myxoid GIST. The American journal of surgical pathology. vol 33. issue 11. 2009-11-12. PMID:19675452. |
immunohistochemically, the tumor cells were positive for alpha smooth muscle actin, and variably for cd10, and were consistently negative for kit, dog1, cd34, desmin, and s100 protein. |
2009-11-12 |
2023-08-12 |
Not clear |
| Guo-Hua Chen, Jian-Pei Fang, Hong-Gui Xu, Si-Xi Liu, Shao-Liang Huan. [Study on the expansion of megakaryocyte progenitors in vitro from cord blood]. Zhongguo shi yan xue ye xue za zhi. vol 13. issue 4. 2008-09-05. PMID:16129055. |
cd34(+) cells were positively isolated using a cd34 progenitor cell isolation kit. |
2008-09-05 |
2023-08-12 |
human |
| Eric P Kleinbaum, Alexander J F Lazar, Elena Tamborini, John C Mcauliffe, Pamela B Sylvestre, Thomas D Sunnenberg, Louise Strong, Lei L Chen, Haesun Choi, Robert S Benjamin, Wei Zhang, Jonathan C Tren. Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor. International journal of cancer. vol 122. issue 3. 2008-01-22. PMID:17943734. |
histopathology revealed microscopic proliferation and nodularity in the myenteric plexus, spindled morphology, diffuse kit but variable cd34 staining and low mitotic rates in the setting of metastatic disease. |
2008-01-22 |
2023-08-12 |
Not clear |
| Ying Jing, Lee R Moore, P Stephen Williams, Jeffrey J Chalmers, Sherif S Farag, Brian Bolwell, Maciej Zborowsk. Blood progenitor cell separation from clinical leukapheresis product by magnetic nanoparticle binding and magnetophoresis. Biotechnology and bioengineering. vol 96. issue 6. 2007-05-17. PMID:17009321. |
the cd34 progenitor cell isolation kit (miltenyi biotec, bergisch gladbach, germany) showed the strongest labeling of kg-1a cells and was selected for progenitor cell enrichment from 11 fresh and 11 cryopreserved clinical leukapheresis samples derived from different donors. |
2007-05-17 |
2023-08-12 |
Not clear |
| Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayam. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions. International journal of molecular medicine. vol 18. issue 6. 2007-01-23. PMID:17089009. |
immunohistochemistry was performed for kit, cd34, ki-67 (as a marker of cell proliferation), and cd31 (as a marker of microvessel density), and apoptosis was assessed by in situ dna nick end-labeling. |
2007-01-23 |
2023-08-12 |
Not clear |
| Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayam. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach. International journal of oncology. vol 28. issue 6. 2006-08-16. PMID:16685437. |
immunohistochemistry was performed for kit, cd34, ki-67 (as a marker of cell proliferation) and cd31 (as a marker of microvessel density), and apoptosis was assessed by in situ dna nick-end labeling. |
2006-08-16 |
2023-08-12 |
Not clear |
| Jean-Michel Coindre, Jean-François Emile, Geneviève Monges, Dominique Ranchère-Vince, Jean-Yves Scoaze. [Gastrointestinal stromal tumors: definition, histological, immunohistochemical, and molecular features, and diagnostic strategy]. Annales de pathologie. vol 25. issue 5. 2006-05-03. PMID:16498290. |
the diagnosis of gist relies on histological arguments (proliferation of spindle-shaped cells in 70% of cases, of epithelioid cells in 20%; histological variants are rare and sometimes misleading) and on immunohistochemical arguments (expression of kit in 95%, usually associated with cd34 expression in 60%-70% of cases). |
2006-05-03 |
2023-08-12 |
Not clear |
| T L Robinson, K Sircar, B R Hewlett, K Chorneyko, R H Riddell, J D Huizing. Gastrointestinal stromal tumors may originate from a subset of CD34-positive interstitial cells of Cajal. The American journal of pathology. vol 156. issue 4. 2000-06-29. PMID:10751339. |
in the human small intestine, sequential immunohistochemical staining for kit and cd34 proteins on the same 3-microm sections showed that some of the icc surrounding auerbach's plexus and icc within the circular muscle layer of the small intestine were positive for both kit and cd34. |
2000-06-29 |
2023-08-12 |
human |