| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vykuntaraju K Gowda, Annsmol P Markose, Varunvenkat M Srinivasan, Viveka Santhosh C Redd. Comparison of Cystathionine Beta-Synthase (CBS) and Methylene Tetrahydrofolate Reductase (MTHFR) Deficiency in Children with Homocystinuria. Indian journal of pediatrics. 2024-09-03. PMID:39225921. |
comparison of cystathionine beta-synthase (cbs) and methylene tetrahydrofolate reductase (mthfr) deficiency in children with homocystinuria. |
2024-09-03 |
2024-09-05 |
Not clear |
| Nadeesha Samarasinghe, Dinithi Mahaliyanage, Sumadee De Silva, Eresha Jasinge, Nimal Punyasiri, H W Dilanth. Association of selected genetic variants in CBS and MTHFR genes in a cohort of children with homocystinuria in Sri Lanka. Journal, genetic engineering & biotechnology. vol 20. issue 1. 2022-12-13. PMID:36512268. |
association of selected genetic variants in cbs and mthfr genes in a cohort of children with homocystinuria in sri lanka. |
2022-12-13 |
2023-08-14 |
Not clear |
| Marly Aparecida Spadotto Balarin, Mariângela Torreglosa Ruiz Cintra, Fernanda Cordeiro, Lucila Naves, Roseane Lopes da Silva-Grecc. Screening of six polymorphisms related with folate metabolism in parents of individuals with Down syndrome. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2019-11-20. PMID:29130768. |
the study aim to investigate mthfr c677t, mthfr a1298c, rfc1 a80g, mtr a2756g, cbs 844ins68, mtrr a66g polymorphisms in down syndrome (ds) parents. |
2019-11-20 |
2023-08-13 |
Not clear |
| Atticus H Hainsworth, Natalie E Yeo, Erica M Weekman, Donna M Wilcoc. Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID). Biochimica et biophysica acta. vol 1862. issue 5. 2019-01-24. PMID:26689889. |
while rare genetic mutations (cbs, mthfr) cause severe hyperhomocysteinemia ([hcy]: 100-200μm), mild-moderate hyperhomocysteinemia ([hcy]: 10-100μm) is common in older people, and is an independent risk factor for stroke and cognitive impairment. |
2019-01-24 |
2023-08-13 |
Not clear |
| Ying Fai Ngai, Dian C Sulistyoningrum, Ryan O'Neill, Sheila M Innis, Joanne Weinberg, Angela M Devli. Prenatal alcohol exposure alters methyl metabolism and programs serotonin transporter and glucocorticoid receptor expression in brain. American journal of physiology. Regulatory, integrative and comparative physiology. vol 309. issue 5. 2016-04-26. PMID:26180184. |
in adulthood (55 days), hippocampal mtr and cbs mrna was lower in e compared with c males, whereas mtr, mat2a, mthfr, and cbs mrna were higher in e compared with c females. |
2016-04-26 |
2023-08-13 |
Not clear |
| Joan Blin, Zalinah Ahmad, Lekhraj Rampal S O Gyanchand Rampal, Norhafizah Mohtarrudin, Abdul Karim Haji Tajudin, Rohayu Shahar Adna. Preliminary assessment of differential expression of candidate genes associated with atherosclerosis. Genes & genetic systems. vol 88. issue 3. 2014-03-14. PMID:24025248. |
this preliminary study was aimed at assessing the expression levels of 11 candidate genes, namely tumor protein (tp53), transforming growth factor, beta receptor ii (tgfbr2), cysthathionenine-beta-synthase (cbs), insulin receptor substrate 1 (irs1), lipoprotein lipase (lpl), methylenetetrahydrofolate reductase (mthfr), thrombomodulin (thbd), lecithin-cholesterol acyltransferase (lcat), matrix metallopeptidase 9 (mmp9), low density lipoprotein receptor (ldlr), and arachidonate 5-lipoxygenase-activating protein (alox5ap) genes associated with ath. |
2014-03-14 |
2023-08-12 |
human |
| Michael D Swartz, Christine B Peterson, Philip J Lupo, Xifeng Wu, Michele R Forman, Margaret R Spitz, Ladia M Hernandez, Marina Vannucci, Sanjay Shet. Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer. PloS one. vol 8. issue 1. 2013-07-22. PMID:23372658. |
this project investigates genes (mthfr, mtr, mtrr, cbs, shmt1, tyms), folate metabolism related nutrients (b vitamins, methionine, choline, and betaine) and their gene-nutrient interactions. |
2013-07-22 |
2023-08-12 |
Not clear |
| Lonneke M L de Lau, Joyce B J van Meurs, André G Uitterlinden, A David Smith, Helga Refsum, Carole Johnston, Monique M B Bretele. Genetic variation in homocysteine metabolism, cognition, and white matter lesions. Neurobiology of aging. vol 31. issue 11. 2011-01-28. PMID:19019492. |
in the population-based rotterdam scan study, we examined the association of seven polymorphisms of genes involved in homocysteine metabolism (mthfr 677c>t, mthfr 1298a>c, rfc 80g>a, tc 776c>g, mtr 2756a>g, mtrr 66a>g, and cbs 844ins68) with plasma total homocysteine, cognitive performance, and cerebral white matter lesions among 1011 non-demented elderly participants. |
2011-01-28 |
2023-08-12 |
human |
| V E Golimbet, I S Lebedeva, M V Alfimova, A N Barkhatova, T V Lezheĭko, N Iu Kolesina, S A Borozdina, L I Abramov. [Homocysteine-related genes and attention in patients with schizophrenia and schizoaffective psychosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 6. 2010-12-20. PMID:20559280. |
molecular-genetic studies revealed the association between schizophrenia and polymorphisms of two genes - methylenetetrahydrofolate reductase (mthfr) and cystathionine-beta-synthase (cbs) involved in the conversion of homocysteine to methionine and cysteine, respectively. |
2010-12-20 |
2023-08-12 |
Not clear |
| Betti Giusti, Claudia Saracini, Paola Bolli, Alberto Magi, Ida Martinelli, Flora Peyvandi, Maurizia Rasura, Massimo Volpe, Luca A Lotta, Speranza Rubattu, Pier Mannuccio Mannucci, Rosanna Abbat. Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism. Thrombosis and haemostasis. vol 104. issue 2. 2010-12-02. PMID:20458436. |
we investigated 58 polymorphisms in ahcy, bhmt, bhmt2, cbs, enosf1, folh1, mthfd1, mthfr, mtr, mtrr, nnmt, pon1, pon2, slc19a1, shmt1, tcn2, tyms genes on genomic dna from 501 young patients who survived ischaemic stroke and 1,211 sex and age comparable controls. |
2010-12-02 |
2023-08-12 |
Not clear |
| Jitender Kumar, Gaurav Garg, Ganesan Karthikeyan, Shantanu Sengupt. Cystathionine beta-synthase 844Ins68 polymorphism is not associated with the levels of homocysteine and cysteine in an Indian population. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. vol 15. issue 3. 2010-06-14. PMID:20175737. |
we have analysed the association of the cbs 844ins68 polymorphism alone and in combination with methylenetetrahydrofolate reductase (mthfr c677t) and choline dehydrogenase (chdh a119c) polymorphisms (the two polymorphisms recently shown to be associated with levels of homocysteine) with homocysteine, cysteine, folate and vitamin b(12) in 817 individuals (397 patients with coronary artery disease and 420 controls). |
2010-06-14 |
2023-08-12 |
Not clear |
| Nongnuch Sirachainan, Werasak Sasanakul, Anannit Visudtibhan, Pornsri Tapanapruksakul, Pimlak Charoenkwan, Praguywan Kadegasem, Umaporn Udomsubpayakul, Ampaiwan Chuansumri. The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children. Thrombosis research. vol 122. issue 1. 2008-08-11. PMID:17996283. |
the effect of polymorphisms of mthfr c677t, a1298c, ms a2756g and cbs 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in thai children. |
2008-08-11 |
2023-08-12 |
Not clear |
| Ying-dong Zhang, Xiao-yan Ke, Wei Shen, Yang Li. Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. vol 20. issue 4. 2007-03-06. PMID:16422253. |
to investigate the relationship of plasma homocysteine (hcy) levels and the gene polymorphisms of n5, n10-methylenetetrahydrofolate reductase (mthfr), cystathionine beta-synthase (cbs) with alzheimer's disease (ad). |
2007-03-06 |
2023-08-12 |
Not clear |
| Jun-Min Wu, Tong-Ge Wang, Yue-Qin Li, Xue-Wen Song, Yong-Yi Liu, Hong-Ruo Yun, Zhen-Yu Zhong, Tian-Hong Zho. [Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke]. Yi chuan = Hereditas. vol 26. issue 3. 2006-04-24. PMID:15640007. |
the study revealed that the genetic mutations of mthfr c677t, cbs t833c,were related with the ischemic stroke. |
2006-04-24 |
2023-08-12 |
Not clear |
| Jun-Min Wu, Tong-Ge Wang, Yue-Qin Li, Xue-Wen Song, Yong-Yi Liu, Hong-Ruo Yun, Zhen-Yu Zhong, Tian-Hong Zho. [Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke]. Yi chuan = Hereditas. vol 26. issue 3. 2006-04-24. PMID:15640007. |
to study genetic mutations of methylenetetrahydrofolate reductase (mthfr) c677t and cystathionine-beta-synthase (cbs) t833c related to homocysteine metabolism in patients with ischemic stroke, the mthfr gene c677t gene mutation and the cbs t833c gene mutation were detected by pcr-rflp or arms method in 74 patients with ischemic stroke and 83 normal people for control. |
2006-04-24 |
2023-08-12 |
Not clear |
| Jun-Min Wu, Tong-Ge Wang, Yue-Qin Li, Xue-Wen Song, Yong-Yi Liu, Hong-Ruo Yun, Zhen-Yu Zhong, Tian-Hong Zho. [Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke]. Yi chuan = Hereditas. vol 26. issue 3. 2006-04-24. PMID:15640007. |
multiple logistic regression analysis showed that together with the t allele in mthfr, the c allele in cbs and age were related to ischemic stroke (p<0.05). |
2006-04-24 |
2023-08-12 |
Not clear |
| Jun-Min Wu, Tong-Ge Wang, Yue-Qin Li, Xue-Wen Song, Yong-Yi Liu, Hong-Ruo Yun, Zhen-Yu Zhong, Tian-Hong Zho. [Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke]. Yi chuan = Hereditas. vol 26. issue 3. 2006-04-24. PMID:15640007. |
the genetic mutations of mthfr c677t and cbs t833c may be genetic factors for ischemic stroke. |
2006-04-24 |
2023-08-12 |
Not clear |
| Luciana Rodrigues Jacy da Silva, Naja Vergani, Luciano de Camargo Galdieri, Marianna Picarelli Ribeiro Porto, Silvia Bragagnolo Longhitano, Decio Brunoni, Vânia D'Almeida, Ana Beatriz Alvarez Pere. Relationship between polymorphisms in genes involved in homocysteine metabolism and maternal risk for Down syndrome in Brazil. American journal of medical genetics. Part A. vol 135. issue 3. 2005-07-05. PMID:15889417. |
in the present study, we determined polymorphisms of mthfr a222v (677c > t), mthfr e429a (1298a > c), mtrr i22m (66a > g), mtr d919g (2756a > g), and cbs 844ins68 and total plasma homocysteine levels (thcy) among 154 mothers of children with down syndrome (ds) and 158 control mothers from brazil. |
2005-07-05 |
2023-08-12 |
Not clear |
| Aliza T Brown, Todd P Smith, Carlos P Cruz, Lionel A Poirier, Debra Simmons, D Keith Williams, Yunfang Wang, John F Eidt, Mohammed M Mours. Intimal hyperplasia following carotid endarterectomy in an insulin-resistant rat model. Metabolism: clinical and experimental. vol 52. issue 7. 2003-08-21. PMID:12870157. |
two weeks post-endarterectomy, blood, liver and carotid tissue were removed to measure plasma insulin, folic acid, and homocysteine, 2 key enzymes of homocysteine metabolism-methylenetetrahydrofolate reductase (mthfr) and cystathionine beta-synthase (cbs)-and percent lumenal stenosis (ih%). |
2003-08-21 |
2023-08-12 |
rat |
| Alessandro Pezzini, Elisabetta Del Zotto, Silvana Archetti, Riccardo Negrini, Paolo Bani, Alberto Albertini, Mario Grassi, Deodato Assanelli, Roberto Gasparotti, Luigi Amedeo Vignolo, Mauro Magoni, Alessandro Padovan. Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke. vol 33. issue 3. 2002-03-18. PMID:11872884. |
plasma homocysteine concentration, c677t mthfr genotype, and 844ins68bp cbs genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. |
2002-03-18 |
2023-08-12 |
human |