| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohamed K Hankir, Christelle Le Fol. Central nervous system pathways targeted by amylin in the regulation of food intake. Biochimie. 2024-10-19. PMID:39426704. |
in this review, we discuss the evidence derived from preclinical studies showing that amylin and the related peptide salmon calcitonin (sct) directly or indirectly target genetically distinct neurons in the caudal hindbrain (nucleus tractus solitarius and area postrema), rostral hindbrain (lateral parabrachial nucleus), midbrain (lateral dorsal tegmentum and ventral tegmental area) and hypothalamus (arcuate nucleus and parasubthalamic nucleus) via activation of amylin and/or calcitonin receptors. |
2024-10-19 |
2024-10-22 |
Not clear |
| Kirsten Dahl, Kirsten Raun, Jakob Lerche Hansen, Christian Poulsen, Charlotta D de la Cour, Trine Ryberg Clausen, Ann Maria Kruse Hansen, Linu M John, Annette Plesner, Gao Sun, Morten Schlein, Rikke Bjerring Skyggebjerg, Thomas Krus. NN1213 - A Potent, Long-Acting, and Selective Analog of Human Amylin. Journal of medicinal chemistry. 2024-07-03. PMID:38960379. |
amylin, a member of the calcitonin family, acts via amylin receptors in the hindbrain and hypothalamus to suppress appetite. |
2024-07-03 |
2024-07-10 |
human |
| Lauren M Stein, Lauren E McGrath, Rinzin Lhamo, Kieran Koch-Laskowski, Samantha M Fortin, Jolanta Skarbaliene, Tamara Baader-Pagler, Rasmus Just, Matthew R Hayes, Elizabeth G Mietlicki-Baas. The long-acting amylin/calcitonin receptor agonist ZP5461 suppresses food intake and body weight in male rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 321. issue 2. 2021-10-07. PMID:34259025. |
here, we evaluate the ability of the novel long-acting amylin/calcitonin receptor agonist zp5461 to reduce feeding and body weight in rats, and also test the role of calcitonin receptors (ctrs) in the dorsal vagal complex (dvc) of the hindbrain in the energy balance effects of chronic zp5461 administration. |
2021-10-07 |
2023-08-13 |
rat |
| Wenwen Cheng, Ian Gonzalez, Warren Pan, Anthony H Tsang, Jessica Adams, Ermelinda Ndoka, Desiree Gordian, Basma Khoury, Karen Roelofs, Simon S Evers, Andrew MacKinnon, Shuangcheng Wu, Henriette Frikke-Schmidt, Jonathan N Flak, James L Trevaskis, Christopher J Rhodes, So-Ichiro Fukada, Randy J Seeley, Darleen A Sandoval, David P Olson, Clemence Blouet, Martin G Myer. Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding. Cell metabolism. vol 31. issue 2. 2021-06-01. PMID:31955990. |
to understand hindbrain pathways involved in the control of food intake, we examined roles for calcitonin receptor (calcr)-containing neurons in the nts. |
2021-06-01 |
2023-08-13 |
mouse |
| J Terrado, I Gerrikagoitia, D Raldúa, V Sorribas, L Martínez-Millán, M Saras. The two mature transcripts of the chick calcitonin gene are expressed within the central nervous system during embryogenesis. Mechanisms of development. vol 77. issue 1. 1999-01-28. PMID:9784613. |
while cgrp mrna is first expressed in motor neurons at rather advanced stages of embryogenesis, calcitonin mrna is expressed in the floor plate and dorsal rhombencephalon from earliest stages. |
1999-01-28 |
2023-08-12 |
chicken |