| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana María Ferreira, Valeria Silva-Álvarez, Igor Kraev, Pinar Uysal-Onganer, Sigrun Lang. Extracellular vesicle and citrullination signatures are novel biomarkers in sturgeon (Acipenser gueldenstaedtii) during chronic stress due to seasonal temperature challenge. Fish & shellfish immunology. 2024-10-19. PMID:39426640. |
the citrullinated proteins and associated gene ontology (go) pathways in sera and serum-evs of chronically heat stressed a. gueldenstaedtii, showed some changes, with specific citrullinated serum protein targets including alpa-2-macroglobulin, alpha globin, calcium-dependent secretion activator, ceruloplasmin, chemokine xc receptor, complement c3 isoforms, complement c9, plectin, selenoprotein and vitellogenin. |
2024-10-19 |
2024-10-22 |
Not clear |
| Elena G Bernea, Viorel I Suica, Elena Uyy, Aurel Cerveanu-Hogas, Raluca M Boteanu, Luminita Ivan, Iuliana Ceausu, Doina A Mihai, Constantin Ionescu-Tîrgoviște, Felicia Antoh. Exosome Proteomics Reveals the Deregulation of Coagulation, Complement and Lipid Metabolism Proteins in Gestational Diabetes Mellitus. Molecules (Basel, Switzerland). vol 27. issue 17. 2022-09-09. PMID:36080270. |
down-regulation of complement c3 (c3), complement c5 (c5), c4-b (c4b), c4b-binding protein beta chain (c4bpb) and c4b-binding protein alpha chain (c4bpa), and up-regulation of c7, c9 and f12 were found in gdm. |
2022-09-09 |
2023-08-14 |
Not clear |
| John O Olanlokun, Wisdom Oshireku Abiodun, Oluwakemi Ebenezer, Neil A Koorbanally, Olufunso Olabode Olorunsog. Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 146. 2021-12-11. PMID:34894518. |
serum tumour necrosis factor alpha (tnf-α), c-reactive protein (crp), interleukins-1 beta (il-1β) and interleukins-6 (il-6) as well as caspases-3, 9 (c3 and c9), p53, serum troponin i (ti) and creatine kinase (ck), were assayed using elisa techniques. |
2021-12-11 |
2023-08-13 |
mouse |
| Moritz Lassé, Anna P Pilbrow, Torsten Kleffmann, Elin Andersson Överström, Anne von Zychlinski, Christopher M A Frampton, Katrina K Poppe, Richard W Troughton, Lynley K Lewis, Timothy C R Prickett, Christopher J Pemberton, Arthur M Richards, Vicky A Camero. Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific reports. vol 11. issue 1. 2021-11-16. PMID:33633217. |
these included (hr = hazard ratio [95% confidence interval] above vs below median): fibrinogen alpha chain (hr = 1.84 [1.19-2.84]); alpha-2-hs-glycoprotein (also called fetuin a) (hr = 1.86 [1.19-2.93]); clusterin isoform 2 (hr = 1.59 [1.06-2.38]); fibrinogen beta chain (hr = 1.55 [1.04-2.30]); hemoglobin subunit beta (hr = 1.49 [1.04-2.15]); complement component c9 (hr = 1.62 [1.01-2.59]), fibronectin isoform 3 (hr = 0.60 [0.37-0.99]); and lipopolysaccharide-binding protein (hr = 1.58 [1.00-2.49]). |
2021-11-16 |
2023-08-13 |
Not clear |
| Milena Fumanal, Daniel E Di Zeo, Victoria Anguís, Catalina Fernández-Diaz, F Javier Alarcón, Rocío Piñera, Nora Albaladejo-Riad, M Angeles Esteban, Miguel A Moriñigo, M Carmen Balebon. Inclusion of dietary Ulva ohnoi 5% modulates Solea senegalensis immune response during Photobacterium damselae subsp. piscicida infection. Fish & shellfish immunology. vol 100. 2020-12-23. PMID:32145450. |
on the contrary, when s. senegalensis specimens were challenged with phdp, modulation of the immune response consisting in increased transcription of genes encoding complement (c1q4, c3, c9), lysozyme g (lysg), tumor necrosis factor alpha (tnfα) as well as those involved in the antioxidant response (gpx, sodmn) and iron metabolism (ferrm, hamp-1) was observed in the liver of fish fed with u. ohnoi. |
2020-12-23 |
2023-08-13 |
Not clear |
| Atsushi Watanabe, Kazumi Satoh, Tomoko Maniwa, Ken-Ichi Matsumot. Proteomic analysis for the identification of serum diagnostic markers for joint hypermobility syndrome. International journal of molecular medicine. vol 37. issue 2. 2016-10-27. PMID:26709396. |
of the 6 proteins, proteins involved in the complement system including complement c1r subcomponent (c1r), vitronectin (vtn), complement component c9 (c9), and c4b-binding protein alpha chain (c4bpa) were identified as increased proteins in sera from patients with jhs compared with those in sera from controls. |
2016-10-27 |
2023-08-13 |
Not clear |
| Pradeep K Naik, Manu Lopus, Ritu Aneja, Surya N Vangapandu, Harish C Josh. In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin). Journal of computer-aided molecular design. vol 26. issue 2. 2012-08-01. PMID:22170255. |
guided by molecular modelling calculations and structure-activity relationships we conjugated at c9 of noscapine, a folate group-a ligand for cellular folate receptor alpha (frα). |
2012-08-01 |
2023-08-12 |
Not clear |
| Aliesha González-Arenas, S Eréndira Avendaño-Vázquez, Alejandro Cabrera-Wrooman, Diana Tapia-Carrillo, Fernando Larrea, Rocío García-Becerra, J Adolfo García-Sáin. Regulation of LPA receptor function by estrogens. Biochimica et biophysica acta. vol 1783. issue 2. 2008-03-26. PMID:18166159. |
17beta-estradiol induced lpa(1) receptor desensitization in c9 cells stably expressing lpa(1) receptors and transiently expressing estrogen receptor alpha. |
2008-03-26 |
2023-08-12 |
Not clear |
| Aliesha González-Arenas, S Eréndira Avendaño-Vázquez, Alejandro Cabrera-Wrooman, Diana Tapia-Carrillo, Fernando Larrea, Rocío García-Becerra, J Adolfo García-Sáin. Regulation of LPA receptor function by estrogens. Biochimica et biophysica acta. vol 1783. issue 2. 2008-03-26. PMID:18166159. |
the results demonstrated that in c9 cells estrogens modulate lpa(1) action through estrogen receptor alpha with the participation of protein kinase c alpha and phosphoinositide 3-kinase. |
2008-03-26 |
2023-08-12 |
Not clear |
| Akiko Hayashi, Hidetoshi Hayashi, Taku Chiba, Satoshi Sasayama, Kikuo Onozak. N-acetylneuraminic acid coupled human recombinant TNFalpha exhibits enhanced anti-tumor activity against Meth-A fibrosarcoma and reduced toxicity. Cancer immunology, immunotherapy : CII. vol 56. issue 4. 2007-05-16. PMID:17031641. |
in order to study the effect of glycosylation on its biological activities and to develop tumor necrosis factor alpha (tnfalpha) with less deleterious effects, n-acetylneuraminic acid (neuac) with a c9 spacer was chemically coupled to human recombinant tnfalpha. |
2007-05-16 |
2023-08-12 |
mouse |
| Yuxiang Huang, Fei Qiao, Ruben Abagyan, Starr Hazard, Stephen Tomlinso. Defining the CD59-C9 binding interaction. The Journal of biological chemistry. vol 281. issue 37. 2006-10-31. PMID:16844690. |
it functions by binding to c8 (alpha chain) and c9 after their structural rearrangement during mac assembly. |
2006-10-31 |
2023-08-12 |
human |
| Suchira Bose, Fiona L L Stratford, Kerry I Broadfoot, Grant G F Mason, A Jennifer Rivet. Phosphorylation of 20S proteasome alpha subunit C8 (alpha7) stabilizes the 26S proteasome and plays a role in the regulation of proteasome complexes by gamma-interferon. The Biochemical journal. vol 378. issue Pt 1. 2004-04-22. PMID:14583091. |
it also decreases the level of phosphorylation of two proteasome alpha subunits, c8 (alpha7) and c9 (alpha3). |
2004-04-22 |
2023-08-12 |
Not clear |
| J M Warren, V A Simon, G Bartolini, K L Erickson, B E Mackey, D S Kelle. Trans-10,cis-12 CLA increases liver and decreases adipose tissue lipids in mice: possible roles of specific lipid metabolism genes. Lipids. vol 38. issue 5. 2004-03-30. PMID:12880104. |
eight-week-old female mice (n = 11 or 12/group) were fed either a control diet or diets supplemented with 0.5% c9,t11-cla or t10,c12-cla isomers or 0.2% of the peroxisome proliferator-activated receptor alpha (pparalpha) agonist fenofibrate for 8 wk. |
2004-03-30 |
2023-08-12 |
mouse |
| Jeffery J Scibek, Mnason E Plumb, James M Sodet. Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit. Biochemistry. vol 41. issue 49. 2003-01-24. PMID:12463754. |
binding of human complement c8 to c9: role of the n-terminal modules in the c8 alpha subunit. |
2003-01-24 |
2023-08-12 |
human |
| Helen M Roche, Enda Noone, Ciaran Sewter, Siobhan Mc Bennett, David Savage, Michael J Gibney, Stephen O'Rahilly, Antonio J Vidal-Pui. Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha. Diabetes. vol 51. issue 7. 2002-07-26. PMID:12086931. |
in contrast, c9,t11-cla increased adipose tissue srebp-1c mrna expression (p = 0.0162) proportionally to the degree of reduction of tumor necrosis factor alpha (tnf-alpha) mrna (p = 0.012). |
2002-07-26 |
2023-08-12 |
mouse |
| A J Rivett, S Bose, P Brooks, K I Broadfoo. Regulation of proteasome complexes by gamma-interferon and phosphorylation. Biochimie. vol 83. issue 3-4. 2001-06-14. PMID:11295498. |
several subunits of proteasomes are phosphorylated including alpha subunits c8 (alpha7) and c9 (alpha3), and atpase subunit s4 (rpt2). |
2001-06-14 |
2023-08-12 |
Not clear |
| S Bose, P Brooks, G G Mason, A J Rivet. gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation. The Biochemical journal. vol 353. issue Pt 2. 2001-03-22. PMID:11139393. |
the c8 alpha subunit showed more than a 50% decrease in phosphorylation, and the phosphorylation of c9 was only barely detectable after gamma-ifn treatment. |
2001-03-22 |
2023-08-12 |
Not clear |
| S F Schreck, C Parker, M E Plumb, J M Sodet. Human complement protein C8 gamma. Biochimica et biophysica acta. vol 1482. issue 1-2. 2000-12-22. PMID:11058761. |
c8 alpha and c8 beta are homologous to c6, c7 and c9 and together these proteins comprise what is referred to as the 'mac protein family'. |
2000-12-22 |
2023-08-12 |
human |
| L Bíró, L Varga, A Pár, E Nemesánszky, A Csepregi, L Telegdy, E Ibrányi, K Dávid, G Horváth, L Szentgyörgyi, I Nagy, L Dalmi, M Abonyi, G Füst, M Horány. Changes in the acute phase complement component and IL-6 levels in patients with chronic hepatitis C receiving interferon alpha-2b. Immunology letters. vol 72. issue 2. 2000-08-25. PMID:10841940. |
in order to study the effect of interferon alpha on the levels of acute phase complement proteins in vivo, serum concentrations of c9 and c1-inhibitor (c1-inh) were measured in patients with chronic hepatitis c before and 3 months after the beginning of interferon alpha2b therapy. |
2000-08-25 |
2023-08-12 |
Not clear |
| L E Anderson, M K Schultz, M C Wiltban. Prostaglandin moieties that determine receptor binding specificity in the bovine corpus luteum. Journal of reproduction and fertility. vol 116. issue 1. 1999-10-12. PMID:10505064. |
the luteal fp receptor binds pgf2 alpha' pgd2 (high affinity), and pge2 (moderate affinity) but not pge1 due to affinity determination by the c9 and c5/c6 moieties, but not the c11 moiety. |
1999-10-12 |
2023-08-12 |
cattle |