Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Samantha J Thomas, Biswarup Ghosh, Zhicheng Wang, Mengxi Yang, Jia Nong, Jenna Severa, Megan C Wright, Yinghui Zhong, Angelo C Lepor. Hepatocyte growth factor delivery to injured cervical spinal cord using an engineered biomaterial protects respiratory neural circuitry and preserves functional diaphragm innervation. Journal of neurotrauma. 2024-07-30. PMID:39078323. |
implantation of hgf hydrogel after unilateral c5 contusion-type sci in rats preserved diaphragm function, as assessed by in vivo recordings of both compound muscle action potentials and inspiratory electromyography amplitudes. |
2024-07-30 |
2024-08-02 |
rat |
Eduardo D Gomes, Biswarup Ghosh, Rui Lima, Miguel Goulão, Tiago Moreira-Gomes, Joana Martins-Macedo, Mark W Urban, Megan C Wright, Jeffrey M Gimble, Nuno Sousa, Nuno A Silva, Angelo C Lepore, António J Salgad. Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury. Frontiers in bioengineering and biotechnology. vol 8. 2020-10-03. PMID:32984278. |
four weeks after injury, compound muscle action potentials (cmaps) were performed to assess functional phrenic motor neuron (phmn) innervation of the diaphragm; no differences were observed amongst groups, confirming that the phmn pool located between c3 and c5 was not affected by the c2 injury or by the treatments. |
2020-10-03 |
2023-08-13 |
rat |
Harold M Burkhart, Jess L Thompson, Randall M Schwart. C3, C4, and C5 Keeps the Diaphragm Alive… and Reduces Morbidity and Hospital Costs. Seminars in thoracic and cardiovascular surgery. vol 30. issue 3. 2018-12-14. PMID:29935229. |
c3, c4, and c5 keeps the diaphragm alive… and reduces morbidity and hospital costs. |
2018-12-14 |
2023-08-13 |
Not clear |
Santiago Alvarez-Argote, Heather M Gransee, Juan C Mora, Jessica M Stowe, Amy J Jorgenson, Gary C Sieck, Carlos B Mantill. The Impact of Midcervical Contusion Injury on Diaphragm Muscle Function. Journal of neurotrauma. vol 33. issue 5. 2016-12-13. PMID:26413840. |
cervical contusion injuries resulted in diaphragm muscle denervation (c3 contusion: 17 ± 4%; c5 contusion: 7 ± 4%; p = 0.047). |
2016-12-13 |
2023-08-13 |
Not clear |
Santiago Alvarez-Argote, Heather M Gransee, Juan C Mora, Jessica M Stowe, Amy J Jorgenson, Gary C Sieck, Carlos B Mantill. The Impact of Midcervical Contusion Injury on Diaphragm Muscle Function. Journal of neurotrauma. vol 33. issue 5. 2016-12-13. PMID:26413840. |
overall, diaphragm root mean square electromyography activity did not change ipsilaterally after c3 or c5 contusion, but increased contralaterally (∼ 11%) after c3 contusion only on the first day post-injury (p = 0.026). |
2016-12-13 |
2023-08-13 |
Not clear |
Santiago Alvarez-Argote, Heather M Gransee, Juan C Mora, Jessica M Stowe, Amy J Jorgenson, Gary C Sieck, Carlos B Mantill. The Impact of Midcervical Contusion Injury on Diaphragm Muscle Function. Journal of neurotrauma. vol 33. issue 5. 2016-12-13. PMID:26413840. |
the pattern of denervation revealed segmental innervation of the diaphragm muscle, with greater denervation ventrally after c3 contusion and dorsally after c5 contusion. |
2016-12-13 |
2023-08-13 |
Not clear |
André De Troye. The action of the canine diaphragm on the lower ribs depends on activation. Journal of applied physiology (Bethesda, Md. : 1985). vol 111. issue 5. 2012-06-05. PMID:21737824. |
in the first, the c5 and c6 phrenic nerve roots were selectively stimulated in 6 animals with the airway occluded, and the level of diaphragm activation was altered by adjusting the stimulation frequency. |
2012-06-05 |
2023-08-12 |
Not clear |
Eric Verin, Jean-Paul Marie, Thomas Similowsk. Cartography of human diaphragmatic innervation: preliminary data. Respiratory physiology & neurobiology. vol 176. issue 1-2. 2011-07-06. PMID:21073984. |
the diaphragm response to electrical stimulation of c3, c4 and c5 was described in three patients undergoing surgical laryngeal reinnervation with an upper phrenic root (surface chest electrodes at anterior, lateral and posterior sites; oesophageal and gastric pressures (pes and pga) to derive transdiaphragmatic pressure (pdi)). |
2011-07-06 |
2023-08-12 |
human |
Eric Verin, Jean-Paul Marie, Thomas Similowsk. Cartography of human diaphragmatic innervation: preliminary data. Respiratory physiology & neurobiology. vol 176. issue 1-2. 2011-07-06. PMID:21073984. |
these singular observations confirm the dominance of c4 in diaphragm innervation but suggest than c5 can be of importance. |
2011-07-06 |
2023-08-12 |
human |
Susan J Davie. "C3, 4, 5 Keeps the Diaphragm Alive." Is phrenic nerve palsy part of the pathophysiological mechanism in strangulation and hanging? Should diaphragm paralysis be excluded in survived cases?: A review of the literature. The American journal of forensic medicine and pathology. vol 31. issue 1. 2010-06-10. PMID:19935388. |
it is formed from c3, c4, and c5 nerve fibers and descends along the anterior surface of the scalenus anterior muscle before entering the thorax to supply motor and sensory input to the diaphragm. |
2010-06-10 |
2023-08-12 |
Not clear |
Susan C Port. Recognition and management of respiratory dysfunction in children with tetraplegia. The journal of spinal cord medicine. vol 27 Suppl 1. 2005-01-07. PMID:15503706. |
respiratory complications of spinal cord injuries at the level of c5 and above may include diaphragm dysfunction, retained airway secretions, recurrent aspiration, nocturnal hypoventilation, and respiratory failure. |
2005-01-07 |
2023-08-12 |
Not clear |
Y Kawaguchi, H Kitagawa, H Nakamura, R Gejo, T Kimur. Neurophysiological tests of respiratory function by compound muscle action potentials from the diaphragm. Detection of lesions in the higher cervical cord. The Journal of bone and joint surgery. British volume. vol 82. issue 5. 2000-09-21. PMID:10963168. |
we recorded compound muscle action potentials (cmaps) from the diaphragm in 15 normal volunteers, nine patients with lesions of the lower cervical cord (c5 to c8), one completely quadriplegic patient (c6) and seven patients with lesions at a higher cervical level (c1 to c4). |
2000-09-21 |
2023-08-12 |
human |
B Sokołowska, K Budzińska, M Pokorsk. [Diaphragmatic electromyogram and respiratory pattern after unilateral and bilateral partial denervation of the diaphragm in the cat]. Pneumonologia i alergologia polska. vol 65. issue 7-8. 1997-12-19. PMID:9410287. |
in the present study we investigated the mechanism of early respiratory compensation of partial paralysis of the sternal and lateral diaphragm due to an unilateral or bilateral section of the c5 rootlet of the phrenic nerves in anesthetized cats. |
1997-12-19 |
2023-08-12 |
cat |
B Sokołowska, K Budzińska, M Pokorsk. [Diaphragmatic electromyogram and respiratory pattern after unilateral and bilateral partial denervation of the diaphragm in the cat]. Pneumonologia i alergologia polska. vol 65. issue 7-8. 1997-12-19. PMID:9410287. |
the results of the study demonstrate that successive c5 denervation of the diaphragm caused a decrease in the ipsilateral diaphragmatic emg. |
1997-12-19 |
2023-08-12 |
cat |
N J Davey, K Murphy, D W Maskill, A Guz, P H Ellawa. Site of facilitation of diaphragm EMG to corticospinal stimulation during inspiration. Respiration physiology. vol 106. issue 2. 1997-03-18. PMID:8971986. |
the electromyographic response of the diaphragm to (a) transcutaneous electrical stimulation (tces) of the spinal cord at c5 and above, (b) transcranial magnetic stimulation (tms) over the motor cortex and (c) transcutaneous electrical stimulation of the phrenic nerve in the neck (tpns), was recorded in six normal subjects at the antero-lateral chest wall. |
1997-03-18 |
2023-08-12 |
human |
J G Enad, M Fournier, G C Siec. Oxidative capacity and capillary density of diaphragm motor units. Journal of applied physiology (Bethesda, Md. : 1985). vol 67. issue 2. 1989-11-15. PMID:2529236. |
motor units in the cat diaphragm (dia) were isolated in situ by microdissection and stimulation of c5 ventral root filaments. |
1989-11-15 |
2023-08-11 |
cat |
M Fournier, G C Siec. Mechanical properties of muscle units in the cat diaphragm. Journal of neurophysiology. vol 59. issue 3. 1988-06-20. PMID:3367195. |
muscle units in the right sternocostal region of the cat diaphragm (dia) were isolated in situ by dissecting filaments of the c5 ventral root. |
1988-06-20 |
2023-08-11 |
cat |
S M Altschuler, R O Davies, A I Pac. Role of medullary inspiratory neurones in the control of the diaphragm during oesophageal stimulation in cats. The Journal of physiology. vol 391. 1988-05-12. PMID:3443947. |
the distension, produced by inflating a balloon in the thoracic portion of the oesophagus, was of sufficient magnitude to induce inhibition of the peri-oesophageal part of the crural diaphragm, with little effect on the respiratory function of the diaphragm as measured by the activity in the c5 branch of the phrenic nerve. |
1988-05-12 |
2023-08-11 |
Not clear |
M L Nochomovitz, A F Dimarco, J T Mortimer, N S Cherniac. Diaphragm activation with intramuscular stimulation in dogs. The American review of respiratory disease. vol 127. issue 3. 1983-04-15. PMID:6830053. |
we studied in 10 supine anesthetized dogs diaphragm contraction produced by electrical activation with intramuscular electrodes surgically implanted in the ventral surface of the diaphragm and compared this with activation of the ipsilateral phrenic nerve (c5, 6, and 7) before it entered the thorax. |
1983-04-15 |
2023-08-12 |
Not clear |