All Relations between brain derived neurotrophic factor and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Youge Qu, Akifumi Eguchi, Li Ma, Xiayun Wan, Chisato Mori, Kenji Hashimot. Role of the gut-brain axis via the subdiaphragmatic vagus nerve in stress resilience of 3,4-methylenedioxymethamphetamine in mice exposed to chronic restrain stress. Neurobiology of disease. 2023-11-13. PMID:37956855. pretreatment with mdma (10\xe2\x80\xafmg/kg/day for 14\xe2\x80\xafdays) blocked anhedonia-like behavior and reduced expression of synaptic proteins and brain-derived neurotrophic factor in the prefrontal cortex (pfc) of crs-exposed mice. 2023-11-13 2023-11-20 mouse
Chao Lyu, Jiahao Zhou, Qiaolin Wu, Xiangyu Fan. Spinal Interferon Regulatory Factor 8 and Brain-derived Neurotrophic Factor in the Prefrontal Cortex are Involved in Pain-induced Depression Relief via Ultrasound-guided Pulsed Radiofrequency in a Rat Spared Nerve Injury Model. Pain physician. vol 26. issue 2. 2023-03-29. PMID:36988364. spinal interferon regulatory factor 8 and brain-derived neurotrophic factor in the prefrontal cortex are involved in pain-induced depression relief via ultrasound-guided pulsed radiofrequency in a rat spared nerve injury model. 2023-03-29 2023-08-14 rat
Thiago \\xc3\\x82ngelo Smaniotto, Angela Maria Casaril, Darling de Andrade Louren\\xc3\\xa7o, Fernanda S Sousa, Fabiana K Seixas, Tiago Collares, Rafael Woloski, Luciano da Silva Pinto, Diego Alves, Lucielli Savegnag. Intranasal administration of interleukin-4 ameliorates depression-like behavior and biochemical alterations in mouse submitted to the chronic unpredictable mild stress: modulation of neuroinflammation and oxidative stress. Psychopharmacology. 2023-03-01. PMID:36856802. moreover, il-4 restored the expression of nuclear factor erythroid 2-related factor 2 (nrf2), nuclear factor kappa b (nf-kb), interleukin 1 beta (il-1\xce\xb2), il-4, brain derived neurotrophic factor (bdnf), and indoleamine 2,3-dioxygenase (ido) in the pfc and hc and modulated oxidative stress markers in these brain structures in stressed mice. 2023-03-01 2023-08-14 mouse
Scott E Hemby, Scot McIntos. Chronic haloperidol administration downregulates select BDNF transcript and protein levels in the dorsolateral prefrontal cortex of rhesus monkeys. Frontiers in psychiatry. vol 14. 2023-02-23. PMID:36816400. post-mortem studies in the prefrontal cortex and hippocampal formation from schizophrenia patients have revealed significant disruptions in the expression molecules associated with cytoarchitecture, synaptic structure, function, and plasticity, known to be regulated in part by brain derived neurotrophic factor (bdnf). 2023-02-23 2023-08-14 monkey
Eleanor Blair Towers, Madison Kilgore, Anousheh Bakhti-Suroosh, Lasyapriya Pidaparthi, Ivy L Williams, Jean M Abel, Wendy J Lync. Sex differences in the neuroadaptations associated with incubated cocaine-craving: A focus on the dorsomedial prefrontal cortex. Frontiers in behavioral neuroscience. vol 16. 2023-01-23. PMID:36688133. the goals of this study were to determine whether cocaine-craving, another key feature of addiction, also develops sooner during withdrawal in females than males and to determine whether there are sex differences in the molecular mechanisms associated with its development focusing on markers known to mediate cocaine-craving in males (i.e., dorsomedial prefrontal cortex, dmpfc, expression of brain-derived neurotrophic factor exon-iv, 2023-01-23 2023-08-14 Not clear
Shuyue Cheng, Wei Wang, Zemeng Zhu, Mingyue Zhao, Hannao Li, Dexiang Liu, Fang Pa. Involvement of brain-derived neurotrophic factor methylation in the prefrontal cortex and hippocampus induced by chronic unpredictable mild stress in male mice. Journal of neurochemistry. 2022-12-01. PMID:36453259. involvement of brain-derived neurotrophic factor methylation in the prefrontal cortex and hippocampus induced by chronic unpredictable mild stress in male mice. 2022-12-01 2023-08-14 mouse
Ana Paula Farias Waltrick, Ana Carolina Felipe da Silva, Bianca Andretto de Mattos, Yane Costa Chaves, R\\xc3\\xbabia Maria Weffort de Oliveira, Jos Prickaerts, Jana\\xc3\\xadna Menezes Zanovel. Long-term treatment with roflumilast improves learning of fear extinction memory and anxiety-like response in a type-1 diabetes mellitus animal model. Behavioural brain research. 2022-11-18. PMID:36400237. in addition, there was an increase in the product of the creb signaling pathway, the pro brain-derived neurotrophic factor, in the hip and pfc of these animals. 2022-11-18 2023-08-14 Not clear
Junhui He, Dongmei Li, Jie Wei, Sheng Wang, Shifeng Chu, Zhao Zhang, Fei He, Dongmei Wei, Yi Li, Jiaxiu Xie, Kedao Lai, Naihong Chen, Guining We. Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis. Neurochemical research. 2022-10-12. PMID:36222958. the concentrations of neurotransmitters were measured by elisa, the expression of connexin 43 (cx43) protein was measured by immunohistochemistry and western-blot, brain derived neurotrophic factor (bdnf), camp-response element binding protein (creb) proteins were measured by western-blot, the pathological changes of prefrontal cortex were observed by hematoxylin-eosin (h&e) staining. 2022-10-12 2023-08-14 human
Yang Yang, Akihiro Mouri, Qiaohui Lu, Kazuo Kunisawa, Hisayoshi Kubota, Masaya Hasegawa, Mami Hirakawa, Yuko Mori, Zou Libo, Kuniaki Saito, Toshitaka Nabeshim. Loureirin C and Xanthoceraside Prevent Abnormal Behaviors Associated with Downregulation of Brain Derived Neurotrophic Factor and AKT/mTOR/CREB Signaling in the Prefrontal Cortex Induced by Chronic Corticosterone Exposure in Mice. Neurochemical research. 2022-07-24. PMID:35871433. loureirin c and xanthoceraside prevent abnormal behaviors associated with downregulation of brain derived neurotrophic factor and akt/mtor/creb signaling in the prefrontal cortex induced by chronic corticosterone exposure in mice. 2022-07-24 2023-08-14 mouse
V Begni, I Pisano, M Marizzoni, F Marchisella, K C Creutzberg, F De Rosa, A Cattaneo, P Gruca, E Litwa, M Papp, M A Riv. Exposure to chronic stress impairs the ability to cope with an acute challenge: Modulation by lurasidone treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 61. 2022-07-13. PMID:35830759. we found that exposure to as produced an upregulation of brain derived neurotrophic factor (bdnf) in the prefrontal cortex of controls animals. 2022-07-13 2023-08-14 rat
Hanxue Wu, Jinzhu Zhuang, Jiawei Wang, Shenglan Yuan, Hui Sun, Jiaxi X. AT FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556110. in both prefrontal cortex and hippocampus, the mrna levels of bdnf (brain-derived neurotrophic factor) and pi4kiii\xce\xb2 (phosphatidylinositol 4-kinase iii\xce\xb2) were found to be significantly lower in hypertensive nt mice. 2022-05-13 2023-08-13 mouse
Nozomi Tokunaga, Tomoyo Takimoto, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Moriok. Downregulation of connexin 43 potentiates amitriptyline-induced brain-derived neurotrophic factor expression in primary astrocytes through lysophosphatidic acid receptor European journal of pharmacology. 2022-05-01. PMID:35490723. downregulation of connexin 43 potentiates amitriptyline-induced brain-derived neurotrophic factor expression in primary astrocytes through lysophosphatidic acid receptor connexin 43 (cx43) expression is decreased in the prefrontal cortex of patients with depression, but its significance is still unknown. 2022-05-01 2023-08-13 Not clear
Shengying Pan, Yaoying Ma, Rongrong Yang, Xu Lu, Qingsheng You, Ting Ye, Chao Huan. Indole-3-Carbinol Selectively Prevents Chronic Stress-Induced Depression-but not Anxiety-Like Behaviors via Suppressing Pro-Inflammatory Cytokine Production and Oxido-Nitrosative Stress in the Brain. Frontiers in pharmacology. vol 13. 2022-03-04. PMID:35242039. further analysis showed that repeated i3c treatment (60\xc2\xa0mg/kg, 10\xc2\xa0days) prevented csds-induced increases in levels of nitrite and malondialdehyde (mda), decreases in contents of glutathione (gsh), and decreases in levels of brain derived neurotrophic factor (bdnf) protein in the hippocampus and prefrontal cortex. 2022-03-04 2023-08-13 mouse
Yuan Zhou, Shao-Fu Li, Li-Sha Deng, Yong-Kang Ma, Gang Lei, Yong-Hui Dan. HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances. Experimental gerontology. 2022-01-07. PMID:34995725. in a battery of behavioural tests, aged wild-type mice showed increased anxiety-like and depression-like behaviours and decreased cognitive performance, along with lower expression levels of glutathione peroxidase, enhanced amount of malondialdehyde, and decreased expression levels of brain-derived neurotrophic factor and tyrosine kinase b in the hippocampus and pfc compared to young wild-type mice. 2022-01-07 2023-08-13 mouse
Euclides Jos\\xc3\\xa9 de Mendon\\xc3\\xa7a Filho, Barbara Barth, Denise Ruschel Bandeira, Randriely Merscher Sobreira de Lima, Danusa Mar Arcego, Carla Dalmaz, Irina Pokhvisneva, Roberto Britto Sassi, Geoffrey B C Hall, Michael J Meaney, Patricia Pelufo Silveir. Cognitive Development and Brain Gray Matter Susceptibility to Prenatal Adversities: Moderation by the Prefrontal Cortex Brain-Derived Neurotrophic Factor Gene Co-expression Network. Frontiers in neuroscience. vol 15. 2021-12-13. PMID:34899157. cognitive development and brain gray matter susceptibility to prenatal adversities: moderation by the prefrontal cortex brain-derived neurotrophic factor gene co-expression network. 2021-12-13 2023-08-13 Not clear
Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. third, early-life selective serotonin reuptake inhibitor exposure alters serotonergic levels, transcription factors expression and brain derived neurotrophic factor levels, resulting in hyperconnectivity within the amygdala and the prefrontal cortex. 2021-11-29 2023-08-13 Not clear
Shuang Zhao, Chengbo Rong, Yi Gao, Linfeng Wu, Xiaoheng Luo, Shuang Song, Yu Liu, Jack Ho Wong, Hexiang Wang, Litao Yi, Tzibun N. Antidepressant-like effect of Ganoderma lucidum spore polysaccharide-peptide mediated by upregulation of prefrontal cortex brain-derived neurotrophic factor. Applied microbiology and biotechnology. vol 105. issue 23. 2021-11-16. PMID:34716786. antidepressant-like effect of ganoderma lucidum spore polysaccharide-peptide mediated by upregulation of prefrontal cortex brain-derived neurotrophic factor. 2021-11-16 2023-08-13 mouse
Gaeul Han, Junhyuk Choi, Seung-Yun Cha, Byung Il Kim, Hee Kyung Kho, Maeng-Jin Jang, Mi Ae Kim, Sungho Maeng, Heeok Hon. Effects of Radix Polygalae on Cognitive Decline and Depression in Estradiol Depletion Mouse Model of Menopause. Current issues in molecular biology. vol 43. issue 3. 2021-10-27. PMID:34698102. in relation to these behaviors, choline acetyltransferase and brain-derived neurotrophic factor in the prefrontal cortex and hippocampus and bcl-2-associated athanogene expression increased in the hippocampus. 2021-10-27 2023-08-13 mouse
Michelle Lima Garcez, Francielle Mina, Tatiani Bellettini-Santos, Fernanda Melo Ribeiro, Alessandra Zanette Ghisi Frassetto, Hemily Batista-Silva, Aline Pereira da Luz, Gustavo Luiz Schiavo, Eduarda Behenck Medeiros, Gabriel Casagrande Zabot, Lara Canever, Alexandra Ioppi Zugno, Josiane Budn. Folic Acid Supplementation in the Gestational Phase of Female Rats Improves Age-Related Memory Impairment and Neuroinflammation in Their Adult and Aged Offspring. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 76. issue 6. 2021-09-15. PMID:33249457. in addition, natural aging and fa deficiency decreased brain-derived neurotrophic factor levels in the hippocampus and nerve growth factor levels in the prefrontal cortex and fa supplementation prevented it. 2021-09-15 2023-08-13 rat
Zhaohong Qin, Li Zhang, Shelly A Cruz, Alexandre F R Stewart, Hsiao-Huei Che. Activation of tyrosine phosphatase PTP1B in pyramidal neurons impairs endocannabinoid signaling by tyrosine receptor kinase trkB and causes schizophrenia-like behaviors in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 11. 2021-06-23. PMID:32610340. modulation of inhibitory inputs onto layer 2/3 pyramidal neurons of the prefrontal cortex relies on ecb signaling from the brain-derived neurotrophic factor receptor trkb, rather than mglur5, and this mechanism was defective in lmo4-deficient mice. 2021-06-23 2023-08-13 mouse