| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan-Lin Wang, Feng Li, Xin Che. Piracetam prevents memory deficit induced by postnatal propofol exposure in mice. European journal of pharmacology. vol 779. 2017-01-06. PMID:26957054. |
similar as piracetam, bdnf supplementary also ameliorated propofol-induced abnormalities of synaptic plasticity-related protein expressions, hippocampal ltp and long-term memory. |
2017-01-06 |
2023-08-13 |
mouse |
| Fangfang Qi, Junhua Yang, Yucen Xia, Qunfang Yuan, Kaihua Guo, Juntao Zou, Zhibin Ya. A(H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice. Brain, behavior, and immunity. vol 53. 2017-01-03. PMID:26576725. |
furthermore, aiv vaccination caused microglia to skew toward an m2-like phenotype (increased arginase-1 and ym1 mrna levels), and elevated levels of brain-derived growth factor (bdnf) and insulin-like growth factor-1 (igf-1) were found in the hippocampus, whereas these effects were offset by anti-tcr antibody treatment. |
2017-01-03 |
2023-08-13 |
mouse |
| Xian-cang Ma, Peng Liu, Xiao-ling Zhang, Wen-hui Jiang, Min Jia, Cai-xia Wang, Ying-ying Dong, Yong-hui Dang, Cheng-ge Ga. Intranasal Delivery of Recombinant AAV Containing BDNF Fused with HA2TAT: a Potential Promising Therapy Strategy for Major Depressive Disorder. Scientific reports. vol 6. 2017-01-03. PMID:26935651. |
western-blotting analysis revealed that bdnf-ha2tat/aav nasal administration enhanced hippocampal bdnf content. |
2017-01-03 |
2023-08-13 |
mouse |
| Xian-cang Ma, Peng Liu, Xiao-ling Zhang, Wen-hui Jiang, Min Jia, Cai-xia Wang, Ying-ying Dong, Yong-hui Dang, Cheng-ge Ga. Intranasal Delivery of Recombinant AAV Containing BDNF Fused with HA2TAT: a Potential Promising Therapy Strategy for Major Depressive Disorder. Scientific reports. vol 6. 2017-01-03. PMID:26935651. |
these results indicate intranasal administration of constructed bdnf-ha2tat/aav exerts anti-depression effect in cms mice by increasing hippocampal bdnf, suggesting that this strategy holds a promising therapeutic potential for mdd. |
2017-01-03 |
2023-08-13 |
mouse |
| D-M Kim, Y-H Lee. Chronic stress-induced memory deficits are reversed by regular exercise via AMPK-mediated BDNF induction. Neuroscience. vol 324. 2017-01-03. PMID:26975895. |
in hippocampal primary culture, phosphorylated-ampk (phospho-ampk) and bdnf levels were enhanced in a dose-dependent manner by 5-amimoimidazole-4-carboxamide riboside (aicar) treatment, and aicar-treated increase was blocked by compound c. a 7-day period of aicar intraperitoneal injections enhanced alternation in the y-maze test and reduced escape latency in water maze test, along with enhanced phospho-ampk and bdnf levels in the hippocampus. |
2017-01-03 |
2023-08-13 |
mouse |
| D-M Kim, Y-H Lee. Chronic stress-induced memory deficits are reversed by regular exercise via AMPK-mediated BDNF induction. Neuroscience. vol 324. 2017-01-03. PMID:26975895. |
also, chronic stress reduced hippocampal neurogenesis (lower ki-67- and doublecortin-positive cells) and mrna levels of bdnf, synaptophysin, and psd-95. |
2017-01-03 |
2023-08-13 |
mouse |
| D-M Kim, Y-H Lee. Chronic stress-induced memory deficits are reversed by regular exercise via AMPK-mediated BDNF induction. Neuroscience. vol 324. 2017-01-03. PMID:26975895. |
hippocampal ampk-engaged bdnf induction is at least in part required for exercise-induced protection against chronic stress. |
2017-01-03 |
2023-08-13 |
mouse |
| G Zunino, A Messina, P Sgadò, G Baj, S Casarosa, Y Bozz. Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice. Neuroscience. vol 324. 2017-01-03. PMID:26987954. |
we first evaluated the expression of different bdnf mrna isoforms in the neocortex and hippocampus of wild-type (wt) and en2(-/-) mice. |
2017-01-03 |
2023-08-13 |
mouse |
| G Zunino, A Messina, P Sgadò, G Baj, S Casarosa, Y Bozz. Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice. Neuroscience. vol 324. 2017-01-03. PMID:26987954. |
quantitative rt-pcr showed a marked down-regulation of several splicing variants of bdnf mrna in the neocortex but not hippocampus of adult en2(-/-) mice, as compared to wt controls. |
2017-01-03 |
2023-08-13 |
mouse |
| G Zunino, A Messina, P Sgadò, G Baj, S Casarosa, Y Bozz. Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice. Neuroscience. vol 324. 2017-01-03. PMID:26987954. |
accordingly, levels of mature bdnf protein were lower in the neocortex but not hippocampus of en2(-/-) mice, as compared to wt. |
2017-01-03 |
2023-08-13 |
mouse |
| Atsushi Sawamoto, Satoshi Okuyama, Kana Yamamoto, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukaw. 3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus. Molecules (Basel, Switzerland). vol 21. issue 4. 2017-01-03. PMID:27120588. |
we previously reported that the citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone (hmf) increased the expression of brain-derived neurotrophic factor (bdnf) in the hippocampus of a transient global ischemia mouse model. |
2017-01-03 |
2023-08-13 |
mouse |
| Atsushi Sawamoto, Satoshi Okuyama, Kana Yamamoto, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukaw. 3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus. Molecules (Basel, Switzerland). vol 21. issue 4. 2017-01-03. PMID:27120588. |
we demonstrated that the hmf treatment ameliorated (1) corticosterone-induced body weight loss, (2) corticosterone-induced depression-like behavior, and (3) corticosterone-induced reductions in bdnf production in the hippocampus. |
2017-01-03 |
2023-08-13 |
mouse |
| Anna Morozova, Eugene Zubkov, Tatyana Strekalova, Zurab Kekelidze, Zinaida Storozeva, Careen A Schroeter, Nataliia Bazhenova, Klaus-Peter Lesch, Brandon H Cline, Vladimir Chekhoni. Ultrasound of alternating frequencies and variable emotional impact evokes depressive syndrome in mice and rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 68. 2017-01-02. PMID:27036099. |
rats showed an increased expression of sert and 5-ht2a receptor, a decreased expression of 5-ht1a receptor in the prefrontal cortex and hippocampus, diminished bdnf on gene and protein levels in the hippocampus. |
2017-01-02 |
2023-08-13 |
mouse |
| Robert Eckenstaler, Volkmar Lessmann, Tanja Brigadsk. CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons. Journal of cell science. vol 129. issue 7. 2016-12-30. PMID:26869227. |
caps1 effects on intragranular ph and regulation of bdnf release from secretory granules in hippocampal neurons. |
2016-12-30 |
2023-08-13 |
Not clear |
| Kay L H Wu, Chih-Wei Wu, You-Lin Tain, Li-Tung Huang, Yung-Mei Chao, Chun-Ying Hung, Jin-Cheng Wu, Siang-Ru Chen, Pei-Chia Tsai, Julie Y H Cha. Environmental stimulation rescues maternal high fructose intake-impaired learning and memory in female offspring: Its correlation with redistribution of histone deacetylase 4. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26872592. |
hippocampal brain-derived neurotrophic factor (bdnf) was decreased in the offspring. |
2016-12-30 |
2023-08-13 |
rat |
| Kay L H Wu, Chih-Wei Wu, You-Lin Tain, Li-Tung Huang, Yung-Mei Chao, Chun-Ying Hung, Jin-Cheng Wu, Siang-Ru Chen, Pei-Chia Tsai, Julie Y H Cha. Environmental stimulation rescues maternal high fructose intake-impaired learning and memory in female offspring: Its correlation with redistribution of histone deacetylase 4. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26872592. |
stimulation to the offspring for 4weeks after winning with an enriched-housing environment effectively rescued the decrease in cognitive function and hippocampal bdnf level; alongside a reversal of the increased distribution of nuclear hdac4. |
2016-12-30 |
2023-08-13 |
rat |
| Kay L H Wu, Chih-Wei Wu, You-Lin Tain, Li-Tung Huang, Yung-Mei Chao, Chun-Ying Hung, Jin-Cheng Wu, Siang-Ru Chen, Pei-Chia Tsai, Julie Y H Cha. Environmental stimulation rescues maternal high fructose intake-impaired learning and memory in female offspring: Its correlation with redistribution of histone deacetylase 4. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26872592. |
together these results suggest that later life environmental stimulation effectively rescues the impairment of hippocampal learning and memory in female offspring to maternal hfd intake through redistributing nuclear hdac4 to increase bdnf expression. |
2016-12-30 |
2023-08-13 |
rat |
| Dong-Hee Choi, Kyoung-Hee Lee, Jongmin Le. Effect of exercise-induced neurogenesis on cognitive function deficit in a rat model of vascular dementia. Molecular medicine reports. vol 13. issue 4. 2016-12-30. PMID:26934837. |
in addition, mature brain‑derived neurotrophic factor (bdnf) levels in the hippocampus were increased in the exercise groups. |
2016-12-30 |
2023-08-13 |
rat |
| Mohammad Jodeiri Farshbaf, Kamran Ghaedi, Timothy L Megraw, Jennifer Curtiss, Mahsa Shirani Faradonbeh, Pooneh Vaziri, Mohammad Hossein Nasr-Esfahan. Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders? Neuromolecular medicine. vol 18. issue 1. 2016-12-28. PMID:26611102. |
fndc5 may also increase the expression of the neurotrophic factor bdnf, a neuroprotective agent, in the hippocampus. |
2016-12-28 |
2023-08-13 |
mouse |
| Mohammad Jodeiri Farshbaf, Kamran Ghaedi, Timothy L Megraw, Jennifer Curtiss, Mahsa Shirani Faradonbeh, Pooneh Vaziri, Mohammad Hossein Nasr-Esfahan. Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders? Neuromolecular medicine. vol 18. issue 1. 2016-12-28. PMID:26611102. |
bdnf is secreted from hippocampus, amygdala, cerebral cortex and hypothalamus neurons and initiates intracellular signaling pathways through trkb receptors. |
2016-12-28 |
2023-08-13 |
mouse |