| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Su-Zhen Guan, Li Ning, Ning Tao, Yu-Long Lian, Ji-Wen Liu, Tzi Bun N. Effects of maternal stress during pregnancy on learning and memory via hippocampal BDNF, Arc (Arg3.1) expression in offspring. Environmental toxicology and pharmacology. vol 46. 2017-02-08. PMID:27474832. |
the expression of hippocampal bdnf and arc mrna and protein were respectively measured using rt-pcr and western blotting. |
2017-02-08 |
2023-08-13 |
rat |
| Su-Zhen Guan, Li Ning, Ning Tao, Yu-Long Lian, Ji-Wen Liu, Tzi Bun N. Effects of maternal stress during pregnancy on learning and memory via hippocampal BDNF, Arc (Arg3.1) expression in offspring. Environmental toxicology and pharmacology. vol 46. 2017-02-08. PMID:27474832. |
collectively, these findings disclose that long-time maternal stress during pregnancy could destroy spatial learning and memory abilities of the offspring, the mechanism of which is related to been improving maternal plasma corticosterone and reduced hippocampal bdnf, arc of offspring rats. |
2017-02-08 |
2023-08-13 |
rat |
| Y Chandrasekhar, E M Ramya, K Navya, G Phani Kumar, K R Anilakuma. Antidepressant like effects of hydrolysable tannins of Terminalia catappa leaf extract via modulation of hippocampal plasticity and regulation of monoamine neurotransmitters subjected to chronic mild stress (CMS). Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 86. 2017-02-08. PMID:28012396. |
moreover, tc administration significantly restored cms induced changes in concentrations of hippocampal neurotransmitters (5-ht, da and ne) as well as levels of acetyl cholinesterase, cortisol, monoamine oxidases (mao-a, mao-b), bdnf, creb, and p-creb. |
2017-02-08 |
2023-08-13 |
mouse |
| Sita Sharan Patel, Neeraj Mahindroo, Malairaman Udayaban. Urtica dioica leaves modulates hippocampal smoothened-glioma associated oncogene-1 pathway and cognitive dysfunction in chronically stressed mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-07. PMID:27470568. |
cus significantly downregulated smo (p<0.05), gli1 (p<0.01), cyclin d1 (p<0.05), bdnf (p<0.01), trkb (p<0.01) and mapk1 (p<0.01) mrna expression in hippocampus as compared to control mice. |
2017-02-07 |
2023-08-13 |
mouse |
| Sita Sharan Patel, Neeraj Mahindroo, Malairaman Udayaban. Urtica dioica leaves modulates hippocampal smoothened-glioma associated oncogene-1 pathway and cognitive dysfunction in chronically stressed mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-07. PMID:27470568. |
chronic ud administration significantly upregulated hippocampal smo (p<0.05), gli1 (p<0.001), cyclin d1 (p<0.05), bdnf (p<0.05), trkb (p<0.05) and mapk1 (p<0.05) in stressed mice. |
2017-02-07 |
2023-08-13 |
mouse |
| b' S Sivilia, C Mangano, S Beggiato, A Giuliani, R Torricella, V A Baldassarro, M Fernandez, L Lorenzini, L Giardino, A C Borelli, L Ferraro, L Calz\\xc3\\xa. CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice. Genes, brain, and behavior. vol 15. issue 5. 2017-02-06. PMID:27108663.' |
finally, the bdnf mrna expression level in the cerebellum, but not in the hippocampus, was reduced compared with wt animals. |
2017-02-06 |
2023-08-13 |
mouse |
| Iris B Hovens, Barbara L van Leeuwen, Massimo A Mariani, Aletta D Kraneveld, Regien G Schoemake. Postoperative cognitive dysfunction and neuroinflammation; Cardiac surgery and abdominal surgery are not the same. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26867718. |
both surgery types induced hippocampal alterations in bdnf signaling. |
2017-02-01 |
2023-08-13 |
rat |
| Richa S Rathod, Amrita A Khaire, Anvita A Kale, Sadhana R Josh. Effect of vitamin B12 and omega-3 fatty acid supplementation on brain neurotrophins and cognition in rats: A multigeneration study. Biochimie. vol 128-129. 2017-01-31. PMID:27569259. |
vitamin b12 supplementation showed comparable bdnf levels in the hippocampus while their levels were lower in the cortex as compared to the control (p < 0.05). |
2017-01-31 |
2023-08-13 |
rat |
| Richa S Rathod, Amrita A Khaire, Anvita A Kale, Sadhana R Josh. Effect of vitamin B12 and omega-3 fatty acid supplementation on brain neurotrophins and cognition in rats: A multigeneration study. Biochimie. vol 128-129. 2017-01-31. PMID:27569259. |
a combined supplementation of vitamin b12 and omega-3 fatty acid showed higher (p < 0.01) levels of dha and ngf in the hippocampus, higher bdnf in both hippocampus and cortex and improved cognitive performance. |
2017-01-31 |
2023-08-13 |
rat |
| Carlos Borges Filho, Cristiano Ricardo Jesse, Franciele Donato, Lucian Del Fabbro, Marcelo Gomes de Gomes, André Tiago Rossito Goes, Leandro Cattelan Souza, Silvana Peterini Boeir. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice. Chemico-biological interactions. vol 260. 2017-01-31. PMID:27818124. |
ob also caused the elevation of tumor necrosis factor-α, interferon-γ, interleukin-1β, interleukin-6, kynurenine (kyn) levels and indoleamine-2,3-dioxygenase activity, as well as occasioned the decrease of 5-hydroxytryptamine (5-ht) and brain-derived neurotrophic factor (bdnf) levels and increase kyn/tryptophan and 5-hydroxyindoleacetic acid/5-ht ratio in the hippocampus. |
2017-01-31 |
2023-08-13 |
mouse |
| Wei Li, Xu Li, Xin Xin, Peng-Cheng Kan, Yan Ya. MicroRNA-613 regulates the expression of brain-derived neurotrophic factor in Alzheimer's disease. Bioscience trends. vol 10. issue 5. 2017-01-30. PMID:27545218. |
in the present study, the mrna and protein expression level of bdnf was detected in serum, and cerebrospinal fluid (csf) of patients with mild cognitive impairment (mci), dementia of alzheimer's type (dat), and hippocampus in app/ps1 mice. |
2017-01-30 |
2023-08-13 |
mouse |
| Wei Li, Xu Li, Xin Xin, Peng-Cheng Kan, Yan Ya. MicroRNA-613 regulates the expression of brain-derived neurotrophic factor in Alzheimer's disease. Bioscience trends. vol 10. issue 5. 2017-01-30. PMID:27545218. |
a significant decrease of bdnf mrna and protein expression was observed in serum and csf of patients and hippocampus in app/ps1 mice compared with the corresponding controls. |
2017-01-30 |
2023-08-13 |
mouse |
| Wei Li, Xu Li, Xin Xin, Peng-Cheng Kan, Yan Ya. MicroRNA-613 regulates the expression of brain-derived neurotrophic factor in Alzheimer's disease. Bioscience trends. vol 10. issue 5. 2017-01-30. PMID:27545218. |
opposite to the alteration of bdnf, mir-613 expression in serum, csf and hippocampus were obviously increased compared to the controls. |
2017-01-30 |
2023-08-13 |
mouse |
| Fabien Boulle, Jodi L Pawluski, Judith R Homberg, Barbie Machiels, Yvet Kroeze, Neha Kumar, Harry W M Steinbusch, Gunter Kenis, Daniel L A Van den Hov. Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring. Developmental psychobiology. vol 58. issue 4. 2017-01-17. PMID:26608001. |
prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal bdnf gene expression in adult male offspring. |
2017-01-17 |
2023-08-13 |
Not clear |
| Fabien Boulle, Jodi L Pawluski, Judith R Homberg, Barbie Machiels, Yvet Kroeze, Neha Kumar, Harry W M Steinbusch, Gunter Kenis, Daniel L A Van den Hov. Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring. Developmental psychobiology. vol 58. issue 4. 2017-01-17. PMID:26608001. |
in the hippocampus, developmental fluoxetine exposure decreased bdnf iv and trkb mrna expression. |
2017-01-17 |
2023-08-13 |
Not clear |
| Fabien Boulle, Jodi L Pawluski, Judith R Homberg, Barbie Machiels, Yvet Kroeze, Neha Kumar, Harry W M Steinbusch, Gunter Kenis, Daniel L A Van den Hov. Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring. Developmental psychobiology. vol 58. issue 4. 2017-01-17. PMID:26608001. |
prenatal stress alone also decreased escape behaviors and decreased hippocampal bdnf iv mrna expression. |
2017-01-17 |
2023-08-13 |
Not clear |
| J Rogers, U Vo, L S Buret, T Y Pang, H Meiklejohn, A Zeleznikow-Johnston, L Churilov, M van den Buuse, A J Hannan, T Renoi. Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment. Translational psychiatry. vol 6. 2017-01-11. PMID:27115125. |
in agreement with these findings, only ex increased hippocampal cell survival and bdnf protein levels. |
2017-01-11 |
2023-08-13 |
mouse |
| Li-Li Qiu, Mu-Huo Ji, Hui Zhang, Jiao-Jiao Yang, Xiao-Ru Sun, Hui Tang, Jing Wang, Wen-Xue Liu, Jian-Jun Yan. NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26254234. |
the levels of nox2, 8-hydroxy-2'-deoxyguanosine (8-oh-dg, a marker of dna oxidation), cd11b (a marker of microglial activation), interleukin-1β (il-1β), and brain-derived neurotrophic factor (bdnf) were determined in the hippocampus and prefrontal cortex at 1 d and 7 d post-surgery, respectively. |
2017-01-10 |
2023-08-13 |
mouse |
| Li-Li Qiu, Mu-Huo Ji, Hui Zhang, Jiao-Jiao Yang, Xiao-Ru Sun, Hui Tang, Jing Wang, Wen-Xue Liu, Jian-Jun Yan. NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26254234. |
our results showed that exploratory laparotomy with isoflurane anesthesia impaired the contextual fear memory, increased expression of nox2, 8-oh-dg, cd11b, and il-1β, and down-regulated bdnf expression in the hippocampus at 7 d post-surgery. |
2017-01-10 |
2023-08-13 |
mouse |
| Miriam S W Wisniewski, Milena Carvalho-Silva, Lara M Gomes, Hugo G Zapelini, Patrícia F Schuck, Gustavo C Ferreira, Giselli Scaini, Emilio L Strec. Intracerebroventricular administration of α-ketoisocaproic acid decreases brain-derived neurotrophic factor and nerve growth factor levels in brain of young rats. Metabolic brain disease. vol 31. issue 2. 2017-01-10. PMID:26586008. |
ours results showed that intracerebroventricular administration of kic decreased bdnf levels in hippocampus, striatum and cerebral cortex, without induce a detectable change in pro-bdnf levels. |
2017-01-10 |
2023-08-13 |
rat |