| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengchen You, Qi Yao, Jianhong Shen, Zhikai Gu, Hui Xu, Zhonghua Wu, Chuanjun Chen, Luozhu L. Antidepressant-like effects of ginsenoside Rg3 in mice via activation of the hippocampal BDNF signaling cascade. Journal of natural medicines. vol 71. issue 2. 2017-04-26. PMID:28013484. |
moreover, rg3 fully restored the csds-induced decrease in the hippocampal bdnf signaling pathway, and use of the bdnf signaling inhibitor blocked the antidepressant effects of rg3. |
2017-04-26 |
2023-08-13 |
mouse |
| Zhengchen You, Qi Yao, Jianhong Shen, Zhikai Gu, Hui Xu, Zhonghua Wu, Chuanjun Chen, Luozhu L. Antidepressant-like effects of ginsenoside Rg3 in mice via activation of the hippocampal BDNF signaling cascade. Journal of natural medicines. vol 71. issue 2. 2017-04-26. PMID:28013484. |
in conclusion, ginsenoside rg3 has antidepressant effects via promotion of the hippocampal bdnf signaling pathway. |
2017-04-26 |
2023-08-13 |
mouse |
| Ruifeng Duan, Xiaohua Liu, Tianhui Wang, Lei Wu, Xiujie Gao, Zhiqing Zhan. Histone Acetylation Regulation in Sleep Deprivation-Induced Spatial Memory Impairment. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27161370. |
therefore, bdnf and its histone acetylation regulation may play important roles in sd-induced spatial memory impairment, whereas hdac inhibition possibly confers protection against sd-induced impairment in spatial memory and hippocampal functions. |
2017-04-17 |
2023-08-13 |
rat |
| Dongmei Wang, Sanqiang Li, Jing Chen, Ling Liu, Xiaoying Zh. The Effects of Astilbin on Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease. Cellular and molecular neurobiology. vol 37. issue 4. 2017-04-17. PMID:27435287. |
furthermore, the expressions of both the camp responsive element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) were significantly increased and the disturbance of akt/gsk-3β signalling pathway was markedly ameliorated in the hippocampus of astilbin-treated (40 mg/kg per day) group. |
2017-04-17 |
2023-08-13 |
mouse |
| Yi Wei, Junhua Hu, Yubing Liang, Yuling Zhong, Dan He, Yi Qin, Li Li, Jing Chen, Qiang Xiao, Yubo Xi. Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus. Molecular medicine reports. vol 14. issue 4. 2017-04-17. PMID:27571870. |
these in vitro data indicated that dexmedetomidine exerted direct neuroprotective effects to prevent cultured hippocampal neuronal injury caused by propofol, accompanied by an increase in the levels of p‑creb, bcl‑2 and bdnf. |
2017-04-17 |
2023-08-13 |
rat |
| b' Ewa Badowska-Szalewska, Beata Ludkiewicz, Rafa\\xc5\\x82 Krawczyk, Natalia Melka, Janusz Mory\\xc5\\x9. Comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor (BDNF) immunoreactivity in old age rats. Acta neurobiologiae experimentalis. vol 77. issue 1. 2017-04-14. PMID:28379217.' |
comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor (bdnf) immunoreactivity in old age rats. |
2017-04-14 |
2023-08-13 |
rat |
| b' Ewa Badowska-Szalewska, Beata Ludkiewicz, Rafa\\xc5\\x82 Krawczyk, Natalia Melka, Janusz Mory\\xc5\\x9. Comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor (BDNF) immunoreactivity in old age rats. Acta neurobiologiae experimentalis. vol 77. issue 1. 2017-04-14. PMID:28379217.' |
the way hippocampal neurons function during stress in old age (critical times of life) is dependent on brain derived neurotrophin factor (bdnf). |
2017-04-14 |
2023-08-13 |
rat |
| Zhijie Zhang, Hongmei Yuan, Huatang Zhao, Bin Qi, Fayin Li, Lijun A. PPARγ activation ameliorates postoperative cognitive decline probably through suppressing hippocampal neuroinflammation in aged mice. International immunopharmacology. vol 43. 2017-04-11. PMID:27940378. |
herein, we showed that surgery induced profound impairment in cognition that was associated with significant decreases in pparγ and bdnf expression, and significant increases in il-1β, iba1-positive cells, and gfap-positive cells in the hippocampus. |
2017-04-11 |
2023-08-13 |
mouse |
| Esen Gumuslu, Oguz Mutlu, Ipek K Celikyurt, Guner Ulak, Furuzan Akar, Faruk Erden, Merve Erta. Exenatide enhances cognitive performance and upregulates neurotrophic factor gene expression levels in diabetic mice. Fundamental & clinical pharmacology. vol 30. issue 4. 2017-04-06. PMID:26935863. |
as the genes involved in neurite remodelling are among the primary targets of regulation, the effects of diabetes and chronic administration of exenatide on brain-derived neurotrophic factor (bdnf) and cyclic adenosine monophosphate (camp) response element binding protein (creb) messenger ribonucleic acid (mrna) levels in the hippocampus of mice were also determined using quantitative real-time polymerase chain reaction (rt-pcr). |
2017-04-06 |
2023-08-13 |
mouse |
| Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zha. Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27432087. |
increased protein expression levels of pcreb, bdnf and sdf-1/cxcr4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment. |
2017-04-06 |
2023-08-13 |
rat |
| Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zha. Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27432087. |
the protein expression levels of bdnf, phosphorylated creb (pcreb), protein kinase a catalytic subunit α, sdf‑1 and cxcr4 in the hippocampus were assayed by western blotting. |
2017-04-06 |
2023-08-13 |
rat |
| Xiao Qian Zhang, Jing Wei Mu, Hui Bin Wang, Jukka Jolkkonen, Ting Ting Liu, Ting Xiao, Mei Zhao, Chao Dong Zhang, Chuan Sheng Zha. Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment. Molecular medicine reports. vol 14. issue 3. 2017-04-06. PMID:27432087. |
furthermore, ee enhanced the protein expression levels of bdnf, pcreb, sdf-1 and cxcr4 in the hippocampus. |
2017-04-06 |
2023-08-13 |
rat |
| R Xu, S R Duan, J W Zhao, C Y Wan. Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 48. issue 8. 2017-04-05. PMID:26108098. |
changes in expression of bdnf and its receptors trkb and p75ntr in the hippocampus of a dog model of chronic alcoholism and abstinence. |
2017-04-05 |
2023-08-13 |
dog |
| R Xu, S R Duan, J W Zhao, C Y Wan. Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 48. issue 8. 2017-04-05. PMID:26108098. |
in this study, we examined the expression of bdnf, tropomyosin receptor kinase b (trkb) and p75 neurotrophin receptor (p75ntr) in the hippocampus of a dog model of chronic alcoholism and abstinence. |
2017-04-05 |
2023-08-13 |
dog |
| R Xu, S R Duan, J W Zhao, C Y Wan. Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 48. issue 8. 2017-04-05. PMID:26108098. |
the number and morphological features of bdnf, trkb and p75ntr-positive neurons in the dentate gyrus (dg), and the ca1, ca3 and ca4 regions of the hippocampus were observed using immunohistochemistry. |
2017-04-05 |
2023-08-13 |
dog |
| Hui Xu, Zhengchen You, Zhonghua Wu, Liang Zhou, Jianhong Shen, Zhikai G. WY14643 Attenuates the Scopolamine-Induced Memory Impairments in Mice. Neurochemical research. vol 41. issue 11. 2017-04-05. PMID:27422264. |
moreover, wy14643 treatment significantly enhanced the expression of brain-derived neurotrophic factor (bdnf) signaling cascade in the hippocampus. |
2017-04-05 |
2023-08-13 |
mouse |
| Sourav Kumar, Amal Chandra Monda. Neuroprotective, Neurotrophic and Anti-oxidative Role of Bacopa monnieri on CUS Induced Model of Depression in Rat. Neurochemical research. vol 41. issue 11. 2017-04-05. PMID:27506204. |
the expression of brain derived neurotrophic factor (bdnf), neuronal marker doublecortin (dcx) in the hippocampus were measured and hippocampal neurogenesis was investigated by 5-bromo-2-deoxyuridine/neuronal nuclei (brdu/neun). |
2017-04-05 |
2023-08-13 |
rat |
| Sourav Kumar, Amal Chandra Monda. Neuroprotective, Neurotrophic and Anti-oxidative Role of Bacopa monnieri on CUS Induced Model of Depression in Rat. Neurochemical research. vol 41. issue 11. 2017-04-05. PMID:27506204. |
these findings revealed that bme exerted neuroprotective effects possibly by promoting hippocampal neurogenesis with elevation of bdnf level and antioxidant defense against oxidative stress. |
2017-04-05 |
2023-08-13 |
rat |
| Masatake Fujimura, Fusako Usuk. Site-specific neural hyperactivity via the activation of MAPK and PKA/CREB pathways triggers neuronal degeneration in methylmercury-intoxicated mice. Toxicology letters. vol 271. 2017-03-28. PMID:28267559. |
however, we did not detect any changes in the expression levels of c-fos and bdnf proteins and no signs of neuronal degeneration in the hippocampus and cerebellum, despite the fact that we could detect accumulation of mehg in these two brain regions. |
2017-03-28 |
2023-08-13 |
mouse |
| Ioanna Markostamou, Anestis Ioannidis, Evgenia Dandi, Maria-Aikaterini Mandyla, Evangelia Nousiopoulou, Constantina Simeonidou, Evangelia Spandou, Despina A Tat. Maternal separation prior to neonatal hypoxia-ischemia: Impact on emotional aspects of behavior and markers of synaptic plasticity in hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 52. 2017-03-27. PMID:27165447. |
synaptic plasticity was evaluated based on bdnf and synaptophysin expression in ca3 and dentate gyrus hippocampal regions. |
2017-03-27 |
2023-08-13 |
rat |