| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoting Wang, Jennifer Lynn Romine, Xiang Gao, Jinhui Che. Aging impairs dendrite morphogenesis of newborn neurons and is rescued by 7, 8-dihydroxyflavone. Aging cell. vol 16. issue 2. 2017-06-19. PMID:28256073. |
we found that systemically administration of 7, 8-dihydroxyflavone (dhf), a small molecule imitating brain-derived neurotrophic factor (bdnf), significantly enhanced dendrite length in the newborn neurons, while it did not promote survival of immature neurons, in the hippocampus of 12-month-old mice. |
2017-06-19 |
2023-08-13 |
mouse |
| Lingpeng Zhu, Chen Nang, Fen Luo, Hong Pan, Kai Zhang, Jingyan Liu, Rui Zhou, Jin Gao, Xiayun Chang, He He, Yue Qiu, Jinglei Wang, Hongyan Long, Yu Liu, Tianhua Ya. Esculetin attenuates lipopolysaccharide (LPS)-induced neuroinflammatory processes and depressive-like behavior in mice. Physiology & behavior. vol 163. 2017-06-16. PMID:27133730. |
in addition, neuroprotection of esculetin was attributed to the upregulations of brain derived neurotrophic factor (bdnf) and phosphorylated tyrosine kinase b (p-trkb) protein expression in hippocampus. |
2017-06-16 |
2023-08-13 |
mouse |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
the aim of the present study was to investigate the effect of "nourishing liver and kidney" acupuncture therapy on motor and cognitive deficits, and the underlying mechanism following cerebral ischemia-reperfusion (i/r) via increasing the expression of brain derived neurotrophic factor (bdnf) and synaptophysin (syn) in the hippocampus. |
2017-06-13 |
2023-08-13 |
rat |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
the expression of bdnf and syn in the hippocampus was detected by immunohistochemical sp method and the synaptic structure in hippocampus area was assessed morphologically and quantitatively at the 3rd, 7th and 14th day. |
2017-06-13 |
2023-08-13 |
rat |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
at the each time point, the expression levels of bdnf and syn in the hippocampal regions increased significantly in the model group as compared with the sham operation group and the acupuncture control group. |
2017-06-13 |
2023-08-13 |
rat |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
it was concluded that the "nourishing liver and kidney" acupuncture therapy has positive effects on behavioral recovery, as well as learning and memory abilities, probably by promoting the expression of bdnf and syn, and synaptic structure reconstruction in the ipsilateral hippocampus after i/r in rats. |
2017-06-13 |
2023-08-13 |
rat |
| Gongying Li, Yanmei Wang, Min Yan, Hongxia Ma, Yanjie Gao, Zexuan Li, Changqi Li, Hongjun Tian, Chuanjun Zhu. Time-dependent co-relation of BDNF and CREB mRNAs in adult rat brains following acute psychological stress in the communication box paradigm. Neuroscience letters. vol 624. 2017-06-06. PMID:27132084. |
the mrna levels of bdnf and creb were significantly decreased, then gradually recovered over 24h to maximum levels in the hippocampus (ca1 region), prefrontal cortex (pfc), central amygdaloid nuclei (ag), shell of accumbens nucleus (nac), periaqueductal gray (pag) and ventral tegmental area, except for the ventral tegmental area (vta). |
2017-06-06 |
2023-08-13 |
human |
| Nasra Naeim Ayuob, Soad Shaker Ali, Mansour Suliaman, Manal Galal Abd El Wahab, Samra Mansour Ahme. The antidepressant effect of musk in an animal model of depression: a histopathological study. Cell and tissue research. vol 366. issue 2. 2017-06-01. PMID:27481508. |
surface markers, proteins and gene expressions of brain-derived neurotropic factor (bdnf) and glucocorticoid receptors (grs) in the hippocampus were assessed. |
2017-06-01 |
2023-08-13 |
mouse |
| Jong-Min Park, Ho-Hyun Seong, Han-Byeol Jin, Youn-Jung Ki. The Effect of Long-Term Environmental Enrichment in Chronic Cerebral Hypoperfusion-Induced Memory Impairment in Rats. Biological research for nursing. vol 19. issue 3. 2017-05-29. PMID:28032515. |
in addition, the vad + ee group showed significantly increased expression of bdnf, pcreb, and vegf in the hippocampus compared to the vad group. |
2017-05-29 |
2023-08-13 |
rat |
| Lorena Navigatore-Fonzo, Andrea Castro, Verónica Pignataro, Marisa Garraza, Marilina Casais, Ana Cecilia Anzulovic. Daily rhythms of cognition-related factors are modified in an experimental model of Alzheimer's disease. Brain research. vol 1660. 2017-05-25. PMID:28163090. |
previously, we observed bdnf and rc3 expression follow a daily rhythmic pattern in the hippocampus of young rats. |
2017-05-25 |
2023-08-13 |
rat |
| Lorena Navigatore-Fonzo, Andrea Castro, Verónica Pignataro, Marisa Garraza, Marilina Casais, Ana Cecilia Anzulovic. Daily rhythms of cognition-related factors are modified in an experimental model of Alzheimer's disease. Brain research. vol 1660. 2017-05-25. PMID:28163090. |
the objective of this study was to investigate the effects of an intracerebroventricular (i.c.v) injection of aggregated aβ peptide (1-42) on temporal patterns of apoe protein, bdnf and rc3 mrna, lipid peroxidation (lpo) and reduced glutathione (gsh) levels, in the rat hippocampus. |
2017-05-25 |
2023-08-13 |
rat |
| Liqiong Guo, Peng-Hui Li, Hua Li, Elena Colicino, Silvia Colicino, Yi Wen, Ruiping Zhang, Xiaotian Feng, Timothy M Barrow, Akin Cayir, Andrea A Baccarelli, Hyang-Min Byu. Effects of environmental noise exposure on DNA methylation in the brain and metabolic health. Environmental research. vol 153. 2017-05-24. PMID:27914298. |
we measured dna methylation in the bdnf, comt, crhr1, mc2r, and snca genes in tissue from four brain regions of the rats (hippocampus, frontal lobe, medulla oblongata, and inferior colliculus). |
2017-05-24 |
2023-08-13 |
human |
| Shujun Jiang, Qinghua Wang, Zan Huang, Anying Song, Yu Peng, Siyuan Hou, Shiying Guo, Weiyun Zhu, Sheng Yan, Zhaoyu Lin, Xiang Ga. Gastric Bypass Surgery Reverses Diabetic Phenotypes in Bdnf-Deficient Mice. The American journal of pathology. vol 186. issue 8. 2017-05-16. PMID:27418549. |
the increased bdnf protein levels in hypothalamus and hippocampus may result from microbiota change after djb surgery. |
2017-05-16 |
2023-08-13 |
mouse |
| Eun-Sang Hwang, Hyun-Bum Kim, Ga-Young Choi, Seok Lee, Sung-Ok Lee, SangSeong Kim, Ji-Ho Par. Acute rosmarinic acid treatment enhances long-term potentiation, BDNF and GluR-2 protein expression, and cell survival rate against scopolamine challenge in rat organotypic hippocampal slice cultures. Biochemical and biophysical research communications. vol 475. issue 1. 2017-05-09. PMID:27163641. |
acute rosmarinic acid treatment enhances long-term potentiation, bdnf and glur-2 protein expression, and cell survival rate against scopolamine challenge in rat organotypic hippocampal slice cultures. |
2017-05-09 |
2023-08-13 |
rat |
| Merav Bruchim-Samuel, Elad Lax, Tomer Gazit, Alexander Friedman, Hadas Ahdoot, Maryia Bairachnaya, Albert Pinhasov, Gal Yadi. Electrical stimulation of the vmPFC serves as a remote control to affect VTA activity and improve depressive-like behavior. Experimental neurology. vol 283. issue Pt A. 2017-05-05. PMID:27181412. |
paes of the vta (10hz, 20min) caused significant, long-term improvement of depressive-like behavior of fsls, concurrently with normalizing intra-vta lfp activity, and increasing vta lfp synchronicity and hippocampal bdnf mrna levels. |
2017-05-05 |
2023-08-13 |
human |
| Mahmoud A Alomari, Omar F Khabour, Karem H Alzoubi, Mohammad A Alzub. Combining restricted diet with forced or voluntary exercises improves hippocampal BDNF and cognitive function in rats. The International journal of neuroscience. vol 126. issue 4. 2017-05-03. PMID:26000806. |
combining restricted diet with forced or voluntary exercises improves hippocampal bdnf and cognitive function in rats. |
2017-05-03 |
2023-08-13 |
rat |
| Mahmoud A Alomari, Omar F Khabour, Karem H Alzoubi, Mohammad A Alzub. Combining restricted diet with forced or voluntary exercises improves hippocampal BDNF and cognitive function in rats. The International journal of neuroscience. vol 126. issue 4. 2017-05-03. PMID:26000806. |
hippocampal bdnf was measured using elisa while learning and memory formation were assessed with the radial arm water maze (rawm) paradigm. |
2017-05-03 |
2023-08-13 |
rat |
| Xiaoqian Luan, Jingyan Tao, Jie Zhang, Ying Xie, Xiangyang Zhang, Hang Su, Jincai H. Increased BDNF may not be associated with cognitive impairment in heroin-dependent patients. Medicine. vol 96. issue 15. 2017-04-28. PMID:28403087. |
a growing number of evidence suggests that brain-derived neurotrophic factor (bdnf) plays an important part in modulating the activities on the basis of hippocampus neural plasticity, such as learning and memory. |
2017-04-28 |
2023-08-13 |
human |
| Zhengchen You, Qi Yao, Jianhong Shen, Zhikai Gu, Hui Xu, Zhonghua Wu, Chuanjun Chen, Luozhu L. Antidepressant-like effects of ginsenoside Rg3 in mice via activation of the hippocampal BDNF signaling cascade. Journal of natural medicines. vol 71. issue 2. 2017-04-26. PMID:28013484. |
antidepressant-like effects of ginsenoside rg3 in mice via activation of the hippocampal bdnf signaling cascade. |
2017-04-26 |
2023-08-13 |
mouse |
| Zhengchen You, Qi Yao, Jianhong Shen, Zhikai Gu, Hui Xu, Zhonghua Wu, Chuanjun Chen, Luozhu L. Antidepressant-like effects of ginsenoside Rg3 in mice via activation of the hippocampal BDNF signaling cascade. Journal of natural medicines. vol 71. issue 2. 2017-04-26. PMID:28013484. |
the changes in the hippocampal brain-derived neurotrophic factor (bdnf) signaling pathway after csds and rg3 treatment were investigated. |
2017-04-26 |
2023-08-13 |
mouse |