| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ken-Ichi Ohta, Shingo Suzuki, Katsuhiko Warita, Tomohiro Kaji, Takashi Kusaka, Takanori Mik. Prolonged maternal separation attenuates BDNF-ERK signaling correlated with spine formation in the hippocampus during early brain development. Journal of neurochemistry. vol 141. issue 2. 2017-07-13. PMID:28178750. |
interestingly, detailed analysis revealed that ms particularly reduced expression of bdnf gene and immediate early genes in the cornu ammonis 1 (ca1) of hippocampus at pd 7. |
2017-07-13 |
2023-08-13 |
rat |
| Liang Zhong, Foquan Luo, Weilu Zhao, Yunlin Feng, Liuqin Wu, Jiamei Lin, Tianyin Liu, Shengqiang Wang, Xuexue You, Wei Zhan. Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway. Journal of cellular and molecular medicine. vol 20. issue 10. 2017-07-11. PMID:27297627. |
after the mwm test, bdnf and trkb transcript and protein levels were measured in rat offspring hippocampus tissues using real-time pcr (rt-pcr) and immunohistochemistry (ihc), respectively. |
2017-07-11 |
2023-08-13 |
rat |
| Liang Zhong, Foquan Luo, Weilu Zhao, Yunlin Feng, Liuqin Wu, Jiamei Lin, Tianyin Liu, Shengqiang Wang, Xuexue You, Wei Zhan. Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway. Journal of cellular and molecular medicine. vol 20. issue 10. 2017-07-11. PMID:27297627. |
it was discovered that maternal exposure to propofol on day e18 impaired spatial learning and memory of rat offspring, decreased mrna and protein levels of bdnf and trkb, and decreased the levels of both phospho-trkb and synaptophysin in the hippocampus. |
2017-07-11 |
2023-08-13 |
rat |
| Deqiang Jing, Francis S Lee, Ipe Nina. The BDNF Val66Met polymorphism enhances glutamatergic transmission but diminishes activity-dependent synaptic plasticity in the dorsolateral striatum. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27378336. |
consistent with the potential role of regulated release of bdnf in synaptic functions, earlier studies have demonstrated that the bdnf val66met polymorphism impairs nmda receptor-mediated synaptic transmission and plasticity in the hippocampus, the medial prefrontal cortex and the central amygdala. |
2017-07-11 |
2023-08-13 |
mouse |
| Qun Wan, Xue Ma, Zhi-Jun Zhang, Ting Sun, Feng Xia, Gang Zhao, Yu-Mei W. Ginsenoside Reduces Cognitive Impairment During Chronic Cerebral Hypoperfusion Through Brain-Derived Neurotrophic Factor Regulated by Epigenetic Modulation. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27021024. |
this improvement was associated with promoted neuron survival and increased bdnf expression in the hippocampus and prefrontal cortex of cch mice. |
2017-07-07 |
2023-08-13 |
mouse |
| Se Jin Jeon, Hong Ju Lee, Hyung Eun Lee, Se Jin Park, Yubeen Gwon, Haneul Kim, Jiabao Zhang, Chan Young Shin, Dong Hyun Kim, Jong Hoon Ry. Oleanolic acid ameliorates cognitive dysfunction caused by cholinergic blockade via TrkB-dependent BDNF signaling. Neuropharmacology. vol 113. issue Pt A. 2017-06-30. PMID:27470063. |
in accordance with previous reports, oleanolic acid enhanced extracellular-signal-regulated kinase 1/2 (erk1/2) and camp response element-binding protein (creb) phosphorylation and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2017-06-30 |
2023-08-13 |
mouse |
| C G Pascuan, M E Di Rosso, J E Pivoz-Avedikian, M R Wald, M A Zorrilla Zubilete, A M Genar. Alteration of neurotrophin and cytokine expression in lymphocytes as novel peripheral markers of spatial memory deficits induced by prenatal stress. Physiology & behavior. vol 173. 2017-06-30. PMID:28167147. |
this alteration occurred in parallel with a decrease in bdnf, an increase in glucocorticoid receptors and an alteration of th1/th2 in the hippocampus. |
2017-06-30 |
2023-08-13 |
mouse |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
hydroxysafflor yellow a increases bdnf and nmdars in the hippocampus in a vascular dementia rat model. |
2017-06-28 |
2023-08-13 |
rat |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
the expression levels of brain-derived neurotrophic factor (bdnf) and two subunits of n-methyl-d-aspartate receptor (nmdar; glun2a and glun2b) in the hippocampus were measured via western blotting. |
2017-06-28 |
2023-08-13 |
rat |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
the western blotting results revealed lower hippocampal bdnf and glun2b expression in the vad group compared with the sham group and significantly higher hippocampal expression in the hsya group compared with the vad group. |
2017-06-28 |
2023-08-13 |
rat |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
the results indicate that hsya may enhance the endogenous expression of bdnf and glun2b, which are associated with the synaptic plasticity of the hippocampus, and may improve spatial learning and memory abilities in a rat model of vad. |
2017-06-28 |
2023-08-13 |
rat |
| Camila Simonetti Pase, Karine Roversi, Katiane Roversi, Luciana Taschetto Vey, Verônica Tironi Dias, Juliana Cristiana Veit, Luana Haselein Maurer, Thiago Duarte, Tatiana Emanuelli, Marta Duarte, Marilise Escobar Bürge. Maternal trans fat intake during pregnancy or lactation impairs memory and alters BDNF and TrkB levels in the hippocampus of adult offspring exposed to chronic mild stress. Physiology & behavior. vol 169. 2017-06-28. PMID:27864043. |
maternal trans fat intake during pregnancy or lactation impairs memory and alters bdnf and trkb levels in the hippocampus of adult offspring exposed to chronic mild stress. |
2017-06-28 |
2023-08-13 |
rat |
| Ya-Min Liu, Chun-Yue Hu, Ji-Duo Shen, Su-Hui Wu, Yu-Cheng Li, Li-Tao Y. Elevation of synaptic protein is associated with the antidepressant-like effects of ferulic acid in a chronic model of depression. Physiology & behavior. vol 169. 2017-06-28. PMID:27940143. |
because of the putative relationship between neurotrophic system and antidepressant-like activity, we also investigated the effects of chronic ferulic acid on the brain-derived neurotrophic factor (bdnf), postsynaptic protein psd95, presynaptic protein synapsin i in both prefrontal cortex and hippocampus. |
2017-06-28 |
2023-08-13 |
mouse |
| Ya-Min Liu, Chun-Yue Hu, Ji-Duo Shen, Su-Hui Wu, Yu-Cheng Li, Li-Tao Y. Elevation of synaptic protein is associated with the antidepressant-like effects of ferulic acid in a chronic model of depression. Physiology & behavior. vol 169. 2017-06-28. PMID:27940143. |
in addition, ferulic acid significantly up-regulated the levels of bdnf, psd95 and synapsin i in the prefrontal cortex and hippocampus. |
2017-06-28 |
2023-08-13 |
mouse |
| Hyo Youl Moon, Andreas Becke, David Berron, Benjamin Becker, Nirnath Sah, Galit Benoni, Emma Janke, Susan T Lubejko, Nigel H Greig, Julie A Mattison, Emrah Duzel, Henriette van Praa. Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function. Cell metabolism. vol 24. issue 2. 2017-06-26. PMID:27345423. |
furthermore, recombinant ctsb application enhanced expression of brain-derived neurotrophic factor (bdnf) and doublecortin (dcx) in adult hippocampal progenitor cells through a mechanism dependent on the multifunctional protein p11. |
2017-06-26 |
2023-08-13 |
mouse |
| Emily V Ho, Stephanie J Klenotich, Matthew S McMurray, Stephanie C Dulaw. Activity-Based Anorexia Alters the Expression of BDNF Transcripts in the Mesocorticolimbic Reward Circuit. PloS one. vol 11. issue 11. 2017-06-26. PMID:27861553. |
scheduled feeding increased the levels of both transcripts in the hippocampus (hpc), increased ncam1 mrna expression in the ventral tegmental area (vta), and decreased bdnf mrna levels in the medial prefrontal cortex (mpfc). |
2017-06-26 |
2023-08-13 |
Not clear |
| Rocío Beatriz Foltran, Silvina Laura Dia. BDNF isoforms: a round trip ticket between neurogenesis and serotonin? Journal of neurochemistry. vol 138. issue 2. 2017-06-23. PMID:27167299. |
this review is focused on bdnf isoforms, their participation in the process of neurogenesis taking place in the hippocampus of adult mammals, and the modulation of their expression by serotonergic agents. |
2017-06-23 |
2023-08-13 |
Not clear |
| Mi Kyoung Seo, Nguyen Ngoc Ly, Chan Hong Lee, Hye Yeon Cho, Cheol Min Choi, Le Hoa Nhu, Jung Goo Lee, Bong Ju Lee, Gyung-Mee Kim, Bong June Yoon, Sung Woo Park, Young Hoon Ki. Early life stress increases stress vulnerability through BDNF gene epigenetic changes in the rat hippocampus. Neuropharmacology. vol 105. 2017-06-22. PMID:26877199. |
early life stress increases stress vulnerability through bdnf gene epigenetic changes in the rat hippocampus. |
2017-06-22 |
2023-08-13 |
rat |
| Mi Kyoung Seo, Nguyen Ngoc Ly, Chan Hong Lee, Hye Yeon Cho, Cheol Min Choi, Le Hoa Nhu, Jung Goo Lee, Bong Ju Lee, Gyung-Mee Kim, Bong June Yoon, Sung Woo Park, Young Hoon Ki. Early life stress increases stress vulnerability through BDNF gene epigenetic changes in the rat hippocampus. Neuropharmacology. vol 105. 2017-06-22. PMID:26877199. |
we examined the epigenetic mechanisms of the bdnf gene in the hippocampus, which may underlie stress vulnerability to postnatal maternal separation (ms) and adult restraint stress (rs). |
2017-06-22 |
2023-08-13 |
rat |
| Elsa M Meylan, Olivier Halfon, Pierre J Magistretti, Jean-René Cardinau. The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression. Neuropharmacology. vol 107. 2017-06-21. PMID:26970016. |
supporting the blunted response to this tricyclic antidepressant, we found that desipramine does not significantly increase the expression of bdnf and nr4a1-3 in the hippocampus and prefrontal cortex of crtc1(-/-) mice. |
2017-06-21 |
2023-08-13 |
mouse |