| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Qiao, Shu-Cheng An, Chang Xu, Xin-Ming M. Role of proBDNF and BDNF in dendritic spine plasticity and depressive-like behaviors induced by an animal model of depression. Brain research. vol 1663. 2017-09-05. PMID:28284898. |
taken together, our results suggest that the ratio of bdnf to probdnf in the hippocampus plays a key role in cums-induced depressive-like behaviors and alterations of dendritic spines in hippocampal ca1 pyramidal neurons. |
2017-09-05 |
2023-08-13 |
rat |
| Luis Eduardo Wearick-Silva, Paul Marshall, Thiago Wendt Viola, Anderson Centeno-Silva, Lucas Araújo de Azeredo, Rodrigo Orso, Xiang Li, Márcio V Donadio, Timothy W Bredy, Rodrigo Grassi-Oliveir. Running during adolescence rescues a maternal separation-induced memory impairment in female mice: Potential role of differential exon-specific BDNF expression. Developmental psychobiology. vol 59. issue 2. 2017-09-04. PMID:27807856. |
the spontaneous object recognition task was performed during adolescence followed by analysis of hippocampal expression of exons i, iv, and ix of the bdnf gene. |
2017-09-04 |
2023-08-13 |
mouse |
| Weisheng Wang, Svetlana Kantorovich, Alex H Babayan, Bowen Hou, Christine M Gall, Gary Lync. Estrogen's Effects on Excitatory Synaptic Transmission Entail Integrin and TrkB Transactivation and Depend Upon β1-integrin function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 11. 2017-08-31. PMID:27272766. |
here we report that brief exposure of adult male hippocampal slices to 1 nm e2 increases the percentage of postsynaptic densities associated with high levels of immunoreactivity for activated forms of the bdnf receptor trkb and β1-integrins, two synaptic receptors that engage actin regulatory rhoa signaling. |
2017-08-31 |
2023-08-13 |
Not clear |
| Filip Bouckaert, Annemiek Dols, Louise Emsell, François-Laurent De Winter, Kristof Vansteelandt, Lene Claes, Stefan Sunaert, Max Stek, Pascal Sienaert, Mathieu Vandenbulck. Relationship Between Hippocampal Volume, Serum BDNF, and Depression Severity Following Electroconvulsive Therapy in Late-Life Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 11. 2017-08-31. PMID:27272769. |
relationship between hippocampal volume, serum bdnf, and depression severity following electroconvulsive therapy in late-life depression. |
2017-08-31 |
2023-08-13 |
Not clear |
| Sooah Jang, Hyunjeong Kim, Jihyeon Jeong, Su Kyoung Lee, Eun Woo Kim, Minsun Park, Chul Hoon Kim, Jong Eun Lee, Kee Namkoong, Eosu Ki. Blunted response of hippocampal AMPK associated with reduced neurogenesis in older versus younger mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 71. 2017-08-30. PMID:27343360. |
administration of either 5-aminoimidazole-4-carboxamide ribonucleoside (aicar; ampk activator) or saline (sham) to young (16-week-old) and old (72-week-old) mice, we measured changes in ampk activity, brain-derived neurotrophic factor (bdnf) expression or neurogenesis in the hippocampus. |
2017-08-30 |
2023-08-13 |
mouse |
| Rongrong Yang, Peng Wang, Zhuo Chen, Wenfeng Hu, Yu Gong, Wei Zhang, Chao Huan. WY-14643, a selective agonist of peroxisome proliferator-activated receptor-α, ameliorates lipopolysaccharide-induced depressive-like behaviors by preventing neuroinflammation and oxido-nitrosative stress in mice. Pharmacology, biochemistry, and behavior. vol 153. 2017-08-25. PMID:28017641. |
in addition, the lps-induced decreases in hippocampal and prefrontal cortical brain-derived neurotrophic factor (bdnf) levels were reversed by wy-14643 pretreatment. |
2017-08-25 |
2023-08-13 |
mouse |
| Yosuke Takeda, Hiroshi Oue, Shinsuke Okada, Akira Kawano, Katsunori Koretake, Makoto Michikawa, Yasumasa Akagawa, Kazuhiro Tsug. Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice. BMC neuroscience. vol 17. issue 1. 2017-08-23. PMID:27919226. |
here we examined the effect of molar loss and powder diet on memory ability and the expression of bdnf mrna in the hippocampus of adult c57bl/6j mice. |
2017-08-23 |
2023-08-13 |
mouse |
| Xing-Wen Fan, Huan-Huan Liu, Hong-Bing Wang, Fu Chen, Yu Yang, Yan Chen, Shi-Kuo Guan, Kai-Liang W. Electroacupuncture Improves Cognitive Function and Hippocampal Neurogenesis after Brain Irradiation. Radiation research. vol 187. issue 6. 2017-08-18. PMID:28375680. |
in addition, electroacupuncture promoted mrna and protein expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2017-08-18 |
2023-08-13 |
rat |
| Xing-Wen Fan, Huan-Huan Liu, Hong-Bing Wang, Fu Chen, Yu Yang, Yan Chen, Shi-Kuo Guan, Kai-Liang W. Electroacupuncture Improves Cognitive Function and Hippocampal Neurogenesis after Brain Irradiation. Radiation research. vol 187. issue 6. 2017-08-18. PMID:28375680. |
in conclusion, electroacupuncture could improve cognitive function and hippocampal neurogenesis after irradiation, and the protective effect of electroacupuncture was associated with the modulation of microglia and upregulation of bdnf in the hippocampus. |
2017-08-18 |
2023-08-13 |
rat |
| Di Lian, Dake He, Jing Wu, Ying Liu, Mingjie Zhu, Jiaming Sun, Feng Chen, Ling L. Exogenous BDNF increases neurogenesis in the hippocampus in experimental Streptococcus pneumoniae meningitis. Journal of neuroimmunology. vol 294. 2017-08-17. PMID:27138098. |
exogenous bdnf increases neurogenesis in the hippocampus in experimental streptococcus pneumoniae meningitis. |
2017-08-17 |
2023-08-13 |
Not clear |
| D Wincewicz, A Juchniewicz, N Waszkiewicz, J J Braszk. Angiotensin II type 1 receptor blockade by telmisartan prevents stress-induced impairment of memory via HPA axis deactivation and up-regulation of brain-derived neurotrophic factor gene expression. Pharmacology, biochemistry, and behavior. vol 148. 2017-08-17. PMID:27375198. |
here we aimed to verify this hypothesis using an animal model of chronic psychological stress (wistar rats restrained 2.5h daily for 21days) with simultaneous oral administration of tlm (1mg/kg), gw9662 - pparγ receptor antagonist (0.5mg/kg), or both in combination, followed by a battery of behavioral tests (open field, elevated plus maze, inhibitory avoidance - ia, object recognition - or), quantitative determination of serum corticosterone (cort) and evaluation of brain-derived neurotrophic factor (bdnf) gene expression in the medial prefrontal cortex (mpfc) and hippocampus (hip). |
2017-08-17 |
2023-08-13 |
human |
| Lengqiu Guo, Zhuangli Guo, Xiaoqing Luo, Rui Liang, Shui Yang, Haigang Ren, Guanghui Wang, Xuechu Zhe. Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory. Neuroscience letters. vol 635. 2017-08-15. PMID:27743798. |
accordingly, rem-sd caused a significant decrease of pcreb in hippocampus and striatum and a significant decrease of bdnf in the hippocampus, striatum and amygdala, however, mp-10 reversed the effects of rem-sd in a dose-dependent manner. |
2017-08-15 |
2023-08-13 |
rat |
| Lengqiu Guo, Zhuangli Guo, Xiaoqing Luo, Rui Liang, Shui Yang, Haigang Ren, Guanghui Wang, Xuechu Zhe. Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory. Neuroscience letters. vol 635. 2017-08-15. PMID:27743798. |
our findings suggest that rem-sd disrupts the consolidation of long-term fear memory and that administration of mp-10 protects the rem-sd-induced deficits in fear memory, which may be due to the mp-10-induced expression of bdnf in the hippocampus, striatum and amygdala, and phosphorylation of creb in the hippocampus and striatum. |
2017-08-15 |
2023-08-13 |
rat |
| Olena Bukalo, Philip R Lee, R Douglas Field. BDNF mRNA abundance regulated by antidromic action potentials and AP-LTD in hippocampus. Neuroscience letters. vol 635. 2017-08-15. PMID:27760383. |
bdnf mrna abundance regulated by antidromic action potentials and ap-ltd in hippocampus. |
2017-08-15 |
2023-08-13 |
mouse |
| Olena Bukalo, Philip R Lee, R Douglas Field. BDNF mRNA abundance regulated by antidromic action potentials and AP-LTD in hippocampus. Neuroscience letters. vol 635. 2017-08-15. PMID:27760383. |
here we report that rapid and persistent down-regulation of different mrna transcripts of the bdnf gene accompanies ap-ltd, and that ap-ltd is abolished in mice with the bdnf gene knocked out in ca1 hippocampal neurons. |
2017-08-15 |
2023-08-13 |
mouse |
| N N Kudryavtseva, D A Smagin, I L Kovalenko, A G Galyamina, G B Vishnivetskaya, V N Babenko, Yu L Orlo. [Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data]. Molekuliarnaia biologiia. vol 51. issue 2. 2017-08-14. PMID:28537235. |
using the data of whole transcriptome analysis (rna-seq), the changes in the expression of serotonergic genes involved in the synthesis, inactivation, and reception of serotonin, as well as of the creb1 (transcription factor) gene and the bdnf (brain-derived neurotrophic factor) gene were detected in the striatum (str), ventral tegmental area (vta), midbrain raphe nuclei (mrn), hypothalamus (hyp), and hippocampus (hip) of defeated and aggressive male mice. |
2017-08-14 |
2023-08-13 |
mouse |
| Alessio Travaglia, Reto Bisaz, Eric S Sweet, Robert D Blitzer, Cristina M Alberin. Infantile amnesia reflects a developmental critical period for hippocampal learning. Nature neuroscience. vol 19. issue 9. 2017-08-10. PMID:27428652. |
the formation and storage of this latent memory requires the hippocampus, follows a sharp temporal boundary and occurs through mechanisms typical of developmental critical periods, including the expression switch of the nmda receptor subunits from 2b to 2a, which is dependent on brain-derived neurotrophic factor (bdnf) and metabotropic glutamate receptor 5 (mglur5). |
2017-08-10 |
2023-08-13 |
rat |
| Nai-Ching Chen, Yao-Chung Chuang, Chi-Wei Huang, Chun-Chung Lui, Chen-Chang Lee, Shih-Wei Hsu, Pin-Hsuan Lin, Yan-Ting Lu, Ya-Ting Chang, Che-Wei Hsu, Chiung-Chih Chan. Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 59. 2017-08-09. PMID:27152461. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophin growth factor mainly expressed in the hippocampus, though it is not known whether the circulating level of bdnf reflects cognitive performance or white matter structural changes in chronic tle. |
2017-08-09 |
2023-08-13 |
Not clear |
| Tomoe Y Nakamura, Shu Nakao, Yukako Nakajo, Jun C Takahashi, Shigeo Wakabayashi, Hiroji Yanamot. Possible Signaling Pathways Mediating Neuronal Calcium Sensor-1-Dependent Spatial Learning and Memory in Mice. PloS one. vol 12. issue 1. 2017-08-09. PMID:28122057. |
furthermore, high voltage electric potential stimulation, which increases the levels of bdnf and promotes spatial learning, significantly increased the levels of ncs-1 concomitant with phosphorylated camkii-α in the hippocampus; suggesting a close relationship between ncs-1 and camkii-α. |
2017-08-09 |
2023-08-13 |
mouse |
| Lívia Ferraz D'avila, Verônica Tironi Dias, Luciana Taschetto Vey, Laura Hautrive Milanesi, Karine Roversi, Tatiana Emanuelli, Marilise Escobar Bürger, Fabíola Trevizol, H Luana Maure. Toxicological aspects of interesterified fat: Brain damages in rats. Toxicology letters. vol 276. 2017-08-08. PMID:28528080. |
in addition, if supplementation impaired short and long-term memory, which were related to increased reactive species generation and protein carbonyl levels, decreased catalase activity, bdnf and trkb levels in the hippocampus. |
2017-08-08 |
2023-08-13 |
rat |