| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
the results showed that increased bdnf levels in the hippocampus and serum of meth-sensitized rats returned to control level after 30 days of abstinence. |
2017-10-10 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
these results suggest that despite the reduction in bdnf levels, reducing the number of neurons, perimeter and area of the hippocampus were stable after abstinence. |
2017-10-10 |
2023-08-13 |
rat |
| Dawei Xu, Chengniu Wang, Wei Zhao, Shengfeng Gao, Zhiming Cu. Antidepressant-like effects of ginsenoside Rg5 in mice: Involving of hippocampus BDNF signaling pathway. Neuroscience letters. vol 645. 2017-10-10. PMID:28257788. |
antidepressant-like effects of ginsenoside rg5 in mice: involving of hippocampus bdnf signaling pathway. |
2017-10-10 |
2023-08-13 |
mouse |
| Dawei Xu, Chengniu Wang, Wei Zhao, Shengfeng Gao, Zhiming Cu. Antidepressant-like effects of ginsenoside Rg5 in mice: Involving of hippocampus BDNF signaling pathway. Neuroscience letters. vol 645. 2017-10-10. PMID:28257788. |
the changes in hippocampal brain-derived neurotrophic factor (bdnf) signaling pathway after csds and rg5 treatment were also examined. |
2017-10-10 |
2023-08-13 |
mouse |
| Dawei Xu, Chengniu Wang, Wei Zhao, Shengfeng Gao, Zhiming Cu. Antidepressant-like effects of ginsenoside Rg5 in mice: Involving of hippocampus BDNF signaling pathway. Neuroscience letters. vol 645. 2017-10-10. PMID:28257788. |
rg5 was also effective in the csds model of depression, and restored the csds-induced decrease in hippocampal bdnf signaling cascade. |
2017-10-10 |
2023-08-13 |
mouse |
| Dawei Xu, Chengniu Wang, Wei Zhao, Shengfeng Gao, Zhiming Cu. Antidepressant-like effects of ginsenoside Rg5 in mice: Involving of hippocampus BDNF signaling pathway. Neuroscience letters. vol 645. 2017-10-10. PMID:28257788. |
collectively, ginsenoside rg5 has antidepressant activities via the activation of hippocampal bdnf system. |
2017-10-10 |
2023-08-13 |
mouse |
| Tianheng Hou, Xiaobo Li, Chongsheng Pen. Borneol enhances the antidepressant effects of asiaticoside by promoting its distribution into the brain. Neuroscience letters. vol 646. 2017-10-10. PMID:28263826. |
hippocampal 5-ht, ne, bdnf, and tnf-α levels were detected, and pathological changes were observed by h&e staining. |
2017-10-10 |
2023-08-13 |
rat |
| Cecilia Csölle, Mária Baranyi, Gabriella Zsilla, Agnes Kittel, Flóra Gölöncsér, Peter Illes, Edit Papp, E Sylvester Vizi, Beáta Sperlág. Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. PloS one. vol 8. issue 6. 2017-10-06. PMID:23805233. |
in conclusion there are several potential mechanisms for the antidepressant phenotype of p2rx7-/- mice, such as the absence of p2rx7-mediated glutamate release, elevated basal bdnf production, enhanced neurogenesis and increased 5-ht bioavailability in the hippocampus. |
2017-10-06 |
2023-08-12 |
mouse |
| Katarzyna Młyniec, Gabriela Starowicz, Magdalena Gaweł, Ewelina Frąckiewicz, Gabriel Nowa. Potential antidepressant-like properties of the TC G-1008, a GPR39 (zinc receptor) agonist. Journal of affective disorders. vol 201. 2017-10-02. PMID:27235821. |
we also found hippocampal gpr39 and brain-derived neurotrophic factor (bdnf) up-regulation following administration of the gpr39 agonist, which may be undiscovered so far as a possible novel agent in the treatment of mood disorders. |
2017-10-02 |
2023-08-13 |
mouse |
| Nasra Naeim Ayuo. Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. Anatomical science international. vol 92. issue 4. 2017-09-28. PMID:27444866. |
protein and gene expressions of brain-derived neurotropic factor (bdnf) and glucocorticoid receptors (grs) in the hippocampus were assessed using elisa and real-time rt-pcr, respectively. |
2017-09-28 |
2023-08-13 |
mouse |
| Nasra Naeim Ayuo. Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. Anatomical science international. vol 92. issue 4. 2017-09-28. PMID:27444866. |
histopathological examination of the hippocampus and immunohistochemical techniques using glial fibrillary acidic protein (gfap), ki67, caspase-3, bdnf and gr were performed. |
2017-09-28 |
2023-08-13 |
mouse |
| Nasra Naeim Ayuo. Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. Anatomical science international. vol 92. issue 4. 2017-09-28. PMID:27444866. |
musk's action may be related to the upregulation of hippocampal gr and bdnf expressions. |
2017-09-28 |
2023-08-13 |
mouse |
| Gina M Fernandez, Brandon J Lew, Lindsey C Vedder, Lisa M Savag. Chronic intermittent ethanol exposure leads to alterations in brain-derived neurotrophic factor within the frontal cortex and impaired behavioral flexibility in both adolescent and adult rats. Neuroscience. vol 348. 2017-09-26. PMID:28257889. |
experiment 2 examined changes in brain-derived neurotrophic factor (bdnf) levels within the frontal cortex (fc) and hippocampus (hpc) at four time points: during intoxication, 24 h after the final etoh exposure (acute abstinence), 3 weeks following abstinence (recovery) and after behavioral testing. |
2017-09-26 |
2023-08-13 |
rat |
| Yoni Genzer, Maayan Dadon, Chen Burg, Nava Chapnik, Oren Fro. Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF). Molecular and cellular endocrinology. vol 430. 2017-09-25. PMID:27113028. |
clock knockdown in ht-4 hippocampal neurons led to 86% up-regulation of bdnf mrna, whereas it led to 60% down-regulation in aml-12 hepatocytes. |
2017-09-25 |
2023-08-13 |
mouse |
| Yoni Genzer, Maayan Dadon, Chen Burg, Nava Chapnik, Oren Fro. Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF). Molecular and cellular endocrinology. vol 430. 2017-09-25. PMID:27113028. |
dietary fat in mice or cultured hepatocytes and hippocampal neurons led to increased bdnf mrna expression. |
2017-09-25 |
2023-08-13 |
mouse |
| Alice Monnier, Philippe Garnier, Aurore Quirie, Nicolas Pernet, Céline Demougeot, Christine Marie, Anne Prigent-Tessie. Effect of short-term exercise training on brain-derived neurotrophic factor signaling in spontaneously hypertensive rats. Journal of hypertension. vol 35. issue 2. 2017-09-25. PMID:28005701. |
decreased brain-derived neurotrophic factor (bdnf) level has been reported in the hippocampus of hypertensive rats. |
2017-09-25 |
2023-08-13 |
rat |
| Jie Fan, Bing Jin Li, Xue Feng Wang, Li Li Zhong, Ran Ji Cu. Ghrelin produces antidepressant-like effect in the estrogen deficient mice. Oncotarget. vol 8. issue 35. 2017-09-25. PMID:28938610. |
furthermore, the western blotting indicated that brain-derived neurotrophic factor (bdnf) in the hippocampus, but not phosphorylated camp response element-binding protein (pcreb)/creb in the frontal cortex, were affected by ghrelin treatment. |
2017-09-25 |
2023-08-13 |
mouse |
| Miyeon Choi, Seung Hoon Lee, Min Hyeop Park, Yong-Seok Kim, Hyeon So. Ketamine induces brain-derived neurotrophic factor expression via phosphorylation of histone deacetylase 5 in rats. Biochemical and biophysical research communications. vol 489. issue 4. 2017-09-22. PMID:28577999. |
in the current study, we demonstrate that the treatment of rats with ketamine results in the dose-dependent rapid upregulation of bdnf promoter iv activity and expression of bdnf exon iv mrnas in rat hippocampal neurons. |
2017-09-22 |
2023-08-13 |
rat |
| Miyeon Choi, Seung Hoon Lee, Min Hyeop Park, Yong-Seok Kim, Hyeon So. Ketamine induces brain-derived neurotrophic factor expression via phosphorylation of histone deacetylase 5 in rats. Biochemical and biophysical research communications. vol 489. issue 4. 2017-09-22. PMID:28577999. |
transfection of histone deacetylase 5 (hdac5) into rat hippocampal neurons similarly induces bdnf mrna expression in response to ketamine, whereas transfection of a hdac5 phosphorylation-defective mutant (ser259 and ser498 replaced by ala259 and ala498), results in the suppression of ketamine-mediated bdnf promoter iv transcriptional activity. |
2017-09-22 |
2023-08-13 |
rat |
| Miyeon Choi, Seung Hoon Lee, Min Hyeop Park, Yong-Seok Kim, Hyeon So. Ketamine induces brain-derived neurotrophic factor expression via phosphorylation of histone deacetylase 5 in rats. Biochemical and biophysical research communications. vol 489. issue 4. 2017-09-22. PMID:28577999. |
viral-mediated hippocampal knockdown of hdac5 induces bdnf mrna and protein expression, and blocks the enhancing effects of ketamine on bdnf expression in both unstressed and stressed rats, and thereby providing evidence for the role of hdac5 in the regulation of bdnf expression. |
2017-09-22 |
2023-08-13 |
rat |