| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine E Kight, Margaret M McCarth. Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870444. |
sex differences and estrogen regulation of bdnf gene expression, but not propeptide content, in the developing hippocampus. |
2017-11-13 |
2023-08-13 |
rat |
| Katherine E Kight, Margaret M McCarth. Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870444. |
in this report, we examined a potential downstream regulator of the effects of estradiol on hippocampal cell proliferation by measuring gene expression of brain-derived neurotrophin (bdnf) in male and female neonatal rats in response to estradiol. |
2017-11-13 |
2023-08-13 |
rat |
| Katherine E Kight, Margaret M McCarth. Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870444. |
males had higher baseline bdnf gene expression in dentate gyrus and ca1 regions of the hippocampus compared with females. |
2017-11-13 |
2023-08-13 |
rat |
| Katherine E Kight, Margaret M McCarth. Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870444. |
neonatal administration of exogenous estradiol resulted in opposite effects on bdnf expression in these areas of the neonatal hippocampus, such that bdnf transcripts increased in ca1 but decreased in dentate. |
2017-11-13 |
2023-08-13 |
rat |
| Katherine E Kight, Margaret M McCarth. Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus. Journal of neuroscience research. vol 95. issue 1-2. 2017-11-13. PMID:27870444. |
the sex- and region-specific effects of estradiol on bdnf expression in the neonatal hippocampus suggest a complex functional relationship between these pleiotropic factors in regulating developmental neurogenesis. |
2017-11-13 |
2023-08-13 |
rat |
| M M Jukić, N Opel, J Ström, T Carrillo-Roa, S Miksys, M Novalen, A Renblom, S C Sim, E M Peñas-Lledó, P Courtet, A Llerena, B T Baune, D J de Quervain, A Papassotiropoulos, R F Tyndale, E B Binder, U Dannlowski, M Ingelman-Sundber. Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment. Molecular psychiatry. vol 22. issue 8. 2017-11-13. PMID:27895323. |
2c19tg mice showed high stress sensitivity, impaired hippocampal bdnf homeostasis in stress, and more despair-like behavior in the forced swim test (fst). |
2017-11-13 |
2023-08-13 |
mouse |
| Joe Herbert, Paul J Lucasse. Depression as a risk factor for Alzheimer's disease: Genes, steroids, cytokines and neurogenesis - What do we need to know? Frontiers in neuroendocrinology. vol 41. 2017-11-09. PMID:26746105. |
gcs and cytokines also reduce bdnf, implicated in both mdd and ad and hippocampal neurogenesis, reinforcing the notion that those cases of mdd with disordered gcs may be a risk for ad. |
2017-11-09 |
2023-08-13 |
Not clear |
| Mariana Colino-Oliveira, Diogo M Rombo, Raquel B Dias, Joaquim A Ribeiro, Ana M Sebastiã. BDNF-induced presynaptic facilitation of GABAergic transmission in the hippocampus of young adults is dependent of TrkB and adenosine A2A receptors. Purinergic signalling. vol 12. issue 2. 2017-11-09. PMID:26897393. |
we conclude that bdnf facilitates gabaergic signaling at the adult hippocampus via a presynaptic mechanism that depends on trkb and adenosine a2ar activation. |
2017-11-09 |
2023-08-13 |
rat |
| Manoel Osório Albuquerque Filho, Betânia Souza de Freitas, Rebeca Carvalho Lacerda Garcia, Pedro Castilhos de Freitas Crivelaro, Nadja Schröder, Maria Noêmia Martins de Lim. Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats. Neuroscience. vol 344. 2017-11-09. PMID:28089578. |
maternal deprivation, a model of early-life stress, hinders memory in adult rats and lessens brain-derived neurotrophic factor (bdnf) levels in the hippocampus in a very heterogeneous way among individuals. |
2017-11-09 |
2023-08-13 |
rat |
| Manoel Osório Albuquerque Filho, Betânia Souza de Freitas, Rebeca Carvalho Lacerda Garcia, Pedro Castilhos de Freitas Crivelaro, Nadja Schröder, Maria Noêmia Martins de Lim. Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats. Neuroscience. vol 344. 2017-11-09. PMID:28089578. |
the main goal of the present study was to investigate the possible epigenetic modulation underlying recognition memory impairment and reduced bdnf levels in the hippocampus of adult maternally deprived rats. |
2017-11-09 |
2023-08-13 |
rat |
| Tae-Woon Kim, Yun-Hee Sun. Regular exercise promotes memory function and enhances hippocampal neuroplasticity in experimental autoimmune encephalomyelitis mice. Neuroscience. vol 346. 2017-11-09. PMID:28108255. |
we found decreased memory ability in eae mice, accompanied by impaired myelination, increased apoptosis and cell proliferation, and decreased bdnf in the hippocampus. |
2017-11-09 |
2023-08-13 |
mouse |
| Yu-Fei Ni, Wei Zhang, Xiao-Feng Bao, Wei Wang, Lu Song, Bo Jian. GM1 ganglioside reverses the cognitive deficits induced by MK801 in mice. Behavioural pharmacology. vol 27. issue 5. 2017-11-08. PMID:26960162. |
it was found that mk801-treated mice showed significant deficits in memory ability compared with control mice in different behavior tests, and this was accompanied by decreased hippocampal bdnf signaling pathway. |
2017-11-08 |
2023-08-13 |
mouse |
| Yu-Fei Ni, Wei Zhang, Xiao-Feng Bao, Wei Wang, Lu Song, Bo Jian. GM1 ganglioside reverses the cognitive deficits induced by MK801 in mice. Behavioural pharmacology. vol 27. issue 5. 2017-11-08. PMID:26960162. |
consecutive administration of gm1 fully restored the mk801-induced cognitive deficits and the impaired bdnf signaling in the hippocampus. |
2017-11-08 |
2023-08-13 |
mouse |
| Laura S van Velzen, Lianne Schmaal, Rick Jansen, Yuri Milaneschi, Esther M Opmeer, Bernet M Elzinga, Nic J A van der Wee, Dick J Veltman, Brenda W J H Pennin. Effect of childhood maltreatment and brain-derived neurotrophic factor on brain morphology. Social cognitive and affective neuroscience. vol 11. issue 11. 2017-11-08. PMID:27405617. |
we examined the effects of cm, bdnf (genotype, gene expression and protein level) and their interactions on hippocampus, amygdala and anterior cingulate cortex (acc) morphology. |
2017-11-08 |
2023-08-13 |
human |
| S Jha, B E Dong, Y Xue, D F Delotterie, M G Vail, K Sakat. Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27648918. |
bdnf protein induction by eet in the hippocampus and frontal cortex was also the largest in ed mice and persisted only in the hippocampus of ed kiv mice after discontinuance of eet. |
2017-11-07 |
2023-08-13 |
mouse |
| Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan, Ipe Ninan, Moses V Cha. Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate. eLife. vol 5. 2017-11-06. PMID:27253067. |
moreover, the effects upon hippocampal bdnf expression were observed after direct ventricular application of β-hydroxybutyrate. |
2017-11-06 |
2023-08-13 |
mouse |
| Bo Jiang, Ying-Jie Wang, Hao Wang, Lu Song, Chao Huang, Qing Zhu, Feng Wu, Wei Zhan. Antidepressant-like effects of fenofibrate in mice via the hippocampal brain-derived neurotrophic factor signalling pathway. British journal of pharmacology. vol 174. issue 2. 2017-11-06. PMID:27861729. |
depression is a neuropsychiatric disorder accompanied by a decrease in the brain-derived neurotrophic factor (bdnf) signalling cascade in the hippocampus. |
2017-11-06 |
2023-08-13 |
mouse |
| Elizabeth Kulikova, Alexander Kuliko. Striatal-enriched Tyrosine Protein Phosphatase (STEP) in the Mechanisms of Depressive Disorders. Current protein & peptide science. vol 18. issue 11. 2017-11-06. PMID:28699511. |
the deficit of bdnf results in progressive degeneration of neurons in the hippocampus and cortex and increases depression risk. |
2017-11-06 |
2023-08-13 |
mouse |
| Elizabeth Kulikova, Alexander Kuliko. Striatal-enriched Tyrosine Protein Phosphatase (STEP) in the Mechanisms of Depressive Disorders. Current protein & peptide science. vol 18. issue 11. 2017-11-06. PMID:28699511. |
at the same time, a step inhibitor, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (tc-2153), increases bdnf expression in the hippocampus and attenuated the depressivelike behavior in mice. |
2017-11-06 |
2023-08-13 |
mouse |
| Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, Marco Emili, Beatrice Uguagliati, Maria Elisa Salvalai, Valeria Bortolotto, Mariagrazia Grilli, Roberto Rimondini, Renata Bartesagh. A flavonoid agonist of the TrkB receptor for BDNF improves hippocampal neurogenesis and hippocampus-dependent memory in the Ts65Dn mouse model of DS. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28882412. |
a flavonoid agonist of the trkb receptor for bdnf improves hippocampal neurogenesis and hippocampus-dependent memory in the ts65dn mouse model of ds. |
2017-11-06 |
2023-08-13 |
mouse |