| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cláudia Vanzella, Juliana Dalibor Neves, Adriana Fernanda Vizuete, Dirceu Aristimunha, Janaína Kolling, Aline Longoni, Carlos Alberto Saraiva Gonçalves, Angela T S Wyse, Carlos Alexandre Nett. Treadmill running prevents age-related memory deficit and alters neurotrophic factors and oxidative damage in the hippocampus of Wistar rats. Behavioural brain research. vol 334. 2017-12-11. PMID:28756215. |
the present study investigated the effects of a treadmill running protocol in young (3month-old) and aged (22month-old) male wistar rats, on: i) cognitive function, as assessed by spatial reference memory in the morris water maze; ii) oxidative stress parameters and the expression of neurotrophic factors bdnf, nt-3, igf-1 and vegf in the hippocampus. |
2017-12-11 |
2023-08-13 |
rat |
| Cláudia Vanzella, Juliana Dalibor Neves, Adriana Fernanda Vizuete, Dirceu Aristimunha, Janaína Kolling, Aline Longoni, Carlos Alberto Saraiva Gonçalves, Angela T S Wyse, Carlos Alexandre Nett. Treadmill running prevents age-related memory deficit and alters neurotrophic factors and oxidative damage in the hippocampus of Wistar rats. Behavioural brain research. vol 334. 2017-12-11. PMID:28756215. |
results demonstrate that the moderate treadmill running exercise: i) prevented age-related deficits in reference memory in the morris water maze; ii) prevented the age-related increase of reactive oxygen species levels and lipid peroxidation in the hippocampus; iii) caused an increase of bdnf, nt-3 and igf-1 expression in the hippocampus of aged rats. |
2017-12-11 |
2023-08-13 |
rat |
| Xin Gao, Fu-Zhi Zhuang, Shou-Jun Qin, Li Zhou, Yun Wang, Qing-Feng Shen, Mei Li, Michelle Villarreal, Lauren Benefield, Shu-Ling Gu, Teng-Fei M. Dexmedetomidine protects against learning and memory impairments caused by electroconvulsive shock in depressed rats: Involvement of the NMDA receptor subunit 2B (NR2B)-ERK signaling pathway. Psychiatry research. vol 243. 2017-12-08. PMID:27455425. |
to further investigate the underlying mechanisms of dex, hippocampal expression of nr2b, p-erk/erk, p-creb/creb, and bdnf were quantified by western blotting. |
2017-12-08 |
2023-08-13 |
rat |
| Fernanda S Petry, Arethuza S Dornelles, Martina Lichtenfels, Fernanda E Valiati, Caroline Brunetto de Farias, Gilberto Schwartsmann, Marise B Parent, Rafael Roesle. Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. Behavioural brain research. vol 307. 2017-11-28. PMID:27025446. |
in addition, the combination of nab and rc-3095 increased hippocampal levels of the brain-derived neurotrophic factor (bdnf). |
2017-11-28 |
2023-08-13 |
rat |
| Glenn R Yamakawa, Connor Lengkeek, Sabrina Salberg, Simon C Spanswick, Richelle Mychasiu. Behavioral and pathophysiological outcomes associated with caffeine consumption and repetitive mild traumatic brain injury (RmTBI) in adolescent rats. PloS one. vol 12. issue 11. 2017-11-28. PMID:29108016. |
finally, modifications to expression of 12 genes (adora2a, app, aqp4, bdnf, bmal1, clock, cry, gfap, orx1, orx2, per, tau), in the prefrontal cortex, hippocampus, and/or the hypothalamus were assessed. |
2017-11-28 |
2023-08-13 |
rat |
| Amine Bah. Sustained lentiviral-mediated overexpression of microRNA124a in the dentate gyrus exacerbates anxiety- and autism-like behaviors associated with neonatal isolation in rats. Behavioural brain research. vol 311. 2017-11-27. PMID:27211062. |
here, we report a stress model demonstrating that neonatal isolation-induced long-lasting hippocampal elevation of mir124a was associated with reduced expression of its target bdnf mrna. |
2017-11-27 |
2023-08-13 |
rat |
| Morgana Moretti, Josiane Budni, Camille Mertins Ribeiro, Débora Kurrle Rieger, Rodrigo Bainy Leal, Ana Lúcia S Rodrigue. Subchronic administration of ascorbic acid elicits antidepressant-like effect and modulates cell survival signaling pathways in mice. The Journal of nutritional biochemistry. vol 38. 2017-11-21. PMID:27721116. |
moreover, we investigated the effect of this vitamin on hippocampal and cerebrocortical brain-derived neurotrophic factor (bdnf) immunocontent, phosphorylation of protein kinase b (akt), extracellular signal-regulated kinase (erk), p38 |
2017-11-21 |
2023-08-13 |
mouse |
| Meysam Amidfar, Gislaine Z Réus, João Quevedo, Yong-Ku Kim, Mohammad Arbab. Effect of co-administration of memantine and sertraline on the antidepressant-like activity and brain-derived neurotrophic factor (BDNF) levels in the rat brain. Brain research bulletin. vol 128. 2017-11-21. PMID:27825855. |
the brain-derived neurotrophic factor (bdnf) levels were assessed in the hippocampus and prefrontal cortex in all groups by elisa sandwich assay. |
2017-11-21 |
2023-08-13 |
rat |
| Meysam Amidfar, Gislaine Z Réus, João Quevedo, Yong-Ku Kim, Mohammad Arbab. Effect of co-administration of memantine and sertraline on the antidepressant-like activity and brain-derived neurotrophic factor (BDNF) levels in the rat brain. Brain research bulletin. vol 128. 2017-11-21. PMID:27825855. |
combined treatment with memantine and sertraline produced stronger increases in the bdnf protein levels in the hippocampus and prefrontal cortex. |
2017-11-21 |
2023-08-13 |
rat |
| Dev Sharan Sams, Stefano Nardone, Dmitriy Getselter, Dana Raz, Moran Tal, Prudhvi Raj Rayi, Hanoch Kaphzan, Ofir Hakim, Evan Elliot. Neuronal CTCF Is Necessary for Basal and Experience-Dependent Gene Regulation, Memory Formation, and Genomic Structure of BDNF and Arc. Cell reports. vol 17. issue 9. 2017-11-21. PMID:27880914. |
in addition, ctcf knockdown attenuates fear-conditioning-induced hippocampal gene expression of key learning genes and loss of long-range interactions at the bdnf and arc loci. |
2017-11-21 |
2023-08-13 |
mouse |
| Bo Cao, Isabelle E Bauer, Ajaykumar N Sharma, Benson Mwangi, Thomas Frazier, Luca Lavagnino, Giovana B Zunta-Soares, Consuelo Walss-Bass, David C Glahn, Flavio Kapczinski, David A Nielsen, Jair C Soare. Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele. Journal of affective disorders. vol 198. 2017-11-20. PMID:27018938. |
reduced hippocampus volume and memory performance in bipolar disorder patients carrying the bdnf val66met met allele. |
2017-11-20 |
2023-08-13 |
Not clear |
| Bo Cao, Isabelle E Bauer, Ajaykumar N Sharma, Benson Mwangi, Thomas Frazier, Luca Lavagnino, Giovana B Zunta-Soares, Consuelo Walss-Bass, David C Glahn, Flavio Kapczinski, David A Nielsen, Jair C Soare. Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele. Journal of affective disorders. vol 198. 2017-11-20. PMID:27018938. |
previous studies investigated the impact of brain-derived neurotrophic factor (bdnf) val66met (rs6265) on hippocampus volumes and neurocognition in bipolar disorders (bd), but the results were not consistent. |
2017-11-20 |
2023-08-13 |
Not clear |
| Bo Cao, Isabelle E Bauer, Ajaykumar N Sharma, Benson Mwangi, Thomas Frazier, Luca Lavagnino, Giovana B Zunta-Soares, Consuelo Walss-Bass, David C Glahn, Flavio Kapczinski, David A Nielsen, Jair C Soare. Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele. Journal of affective disorders. vol 198. 2017-11-20. PMID:27018938. |
this study aimed to investigate the effect of bdnf polymorphism on hippocampus volumes and memory performance in well-characterized adult populations diagnosed with type i bd (bd-i) and major depressive disorder (mdd) compared with healthy controls (hc). |
2017-11-20 |
2023-08-13 |
Not clear |
| Majid Motaghinejad, Zeinab Seyedjavadein, Manijeh Motevalian, Majid Asad. The neuroprotective effect of lithium against high dose methylphenidate: Possible role of BDNF. Neurotoxicology. vol 56. 2017-11-20. PMID:27343358. |
lithium has the potential to act as a neuroprotective agent against mph induced toxicity in rat brain and this might be mediated by bdnf expression in hippocampus of rats. |
2017-11-20 |
2023-08-13 |
rat |
| Rubén García-Cabrerizo, M Julia García-Fuste. Comparative effects of amphetamine-like psychostimulants on rat hippocampal cell genesis at different developmental ages. Neurotoxicology. vol 56. 2017-11-20. PMID:27373168. |
moreover, the present results, in line with previous data, suggest a possible role for the neuroplasticity marker bdnf and serotonin in regulating cell survival, as mbdnf protein regulation paralleled hippocampal cell survival and 5-ht |
2017-11-20 |
2023-08-13 |
rat |
| Cristina Borralleras, Susana Mato, Thierry Amédée, Carlos Matute, Christophe Mulle, Luis A Pérez-Jurado, Victoria Campuzan. Synaptic plasticity and spatial working memory are impaired in the CD mouse model of Williams-Beuren syndrome. Molecular brain. vol 9. issue 1. 2017-11-17. PMID:27485321. |
reduced levels of brain-derived neurotrophic factor (bdnf) were present in the ca1-ca3 hippocampal region of cd mice, which could account for ltp deficits in these mice. |
2017-11-17 |
2023-08-13 |
mouse |
| Manal Tabbaa, Kelly Lei, Yan Liu, Zuoxin Wan. Paternal deprivation affects social behaviors and neurochemical systems in the offspring of socially monogamous prairie voles. Neuroscience. vol 343. 2017-11-17. PMID:27998780. |
interestingly, mo subjects showed consistent increases in both gene and protein expression of the brain-derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (trkb) as well as the levels of total histone 3 and histone 3 acetylation in the hippocampus compared to mf subjects. |
2017-11-17 |
2023-08-13 |
human |
| J L Hill, N F Hardy, D V Jimenez, K R Maynard, A S Kardian, C J Pollock, R J Schloesser, K Martinowic. Loss of promoter IV-driven BDNF expression impacts oscillatory activity during sleep, sensory information processing and fear regulation. Translational psychiatry. vol 6. issue 8. 2017-11-13. PMID:27552586. |
fear extinction is controlled by hippocampal-prefrontal cortical bdnf signaling, and neurophysiological communication patterns between the hippocampus (hpc) and medial prefrontal cortex (mpfc) correlate with behavioral performance during extinction. |
2017-11-13 |
2023-08-13 |
mouse |
| Ernest Palomer, Adrián Martín-Segura, Shishir Baliyan, Tariq Ahmed, Detlef Balschun, Cesar Venero, Mauricio G Martin, Carlos G Dott. Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons. Cell reports. vol 16. issue 11. 2017-11-13. PMID:27626660. |
aging triggers a repressive chromatin state at bdnf promoters in hippocampal neurons. |
2017-11-13 |
2023-08-13 |
mouse |
| Ernest Palomer, Adrián Martín-Segura, Shishir Baliyan, Tariq Ahmed, Detlef Balschun, Cesar Venero, Mauricio G Martin, Carlos G Dott. Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons. Cell reports. vol 16. issue 11. 2017-11-13. PMID:27626660. |
here, we show that the transcriptional induction of bdnf by a mnemonic stimulus is impaired in aged hippocampal neurons. |
2017-11-13 |
2023-08-13 |
mouse |